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List of works by Helena Castro

Automatic Annotation of Leishmania Infections in Fluorescence Microscopy Images

Automatic Assessment of Leishmania Infection Indexes on In Vitro Macrophage Cell Cultures

article

Automatic Spectral Unmixing of Leishmania Infection Macrophage Cell Cultures Image

article

Calcium and magnesium ions modulate the oligomeric state and function of mitochondrial 2-Cys peroxiredoxins in Leishmania parasites.

scientific article published on 14 March 2017

Chaperone activation and client binding of a 2-cysteine peroxiredoxin

scientific article published in Nature Communications

Chapter 16. The Redox Metabolism and Oxidative Stress in Leishmania as a Crossroads for the Lethal Effect of Drugs

Chemicals with sweet aroma descriptors found in Portuguese wines from the Douro region: 2,6,6-trimethylcyclohex-2-ene-1,4-dione and diacetyl

scientific article

Complementary antioxidant defense by cytoplasmic and mitochondrial peroxiredoxins in Leishmania infantum

scientific article

Detection and separation of overlapping cells based on contour concavity for Leishmania images

scientific article published on 9 April 2014

Development of an automated image analysis protocol for quantification of intracellular forms of Leishmania spp

scientific article published in PLoS ONE

Functional insight into the glycosomal peroxiredoxin of Leishmania

scientific article published on 09 October 2019

Genetic and chemical analyses reveal that trypanothione synthetase but not glutathionylspermidine synthetase is essential for Leishmania infantum

scientific article published on 20 May 2014

Heme as a source of iron to Leishmania infantum amastigotes

scientific article published on 01 November 2008

Identification of antibodies to Leishmania silent information regulatory 2 (SIR2) protein homologue during canine natural infections: pathological implications.

scientific article published in April 2003

Investigation of trypanothione reductase inhibitory activity by 1,3,4-thiadiazolium-2-aminide derivatives and molecular docking studies

scientific article published on 14 January 2012

Leishmania infantum Enhances Migration of Macrophages via a Phosphoinositide 3-Kinase γ-Dependent Pathway

scientific article published on 07 May 2020

Leishmania infantum: Provision of reducing equivalents to the mitochondrial tryparedoxin/tryparedoxin peroxidase system

scientific article published on 09 September 2008

Leishmania mitochondrial peroxiredoxin plays a crucial peroxidase-unrelated role during infection: insight into its novel chaperone activity

scientific article

LiZIP3 is a cellular zinc transporter that mediates the tightly regulated import of zinc in Leishmania infantum parasites

scientific article published on 11 March 2015

Mitochondrial peroxiredoxin functions as crucial chaperone reservoir in Leishmania infantum

scientific article

Mitochondrial redox metabolism in trypanosomatids is independent of tryparedoxin activity

scientific article

Peroxidases of trypanosomatids

scientific article published on September 2008

Plasmodium chabaudi chabaudi malaria parasites can develop stable resistance to atovaquone with a mutation in the cytochrome b gene

scientific article

Redox Metabolism in Mitochondria of Trypanosomatids

scientific article published on November 15, 2012

Specificity and kinetics of a mitochondrial peroxiredoxin of Leishmania infantum

scientific article

Synthesis and evaluation of novel chromanone and quinolinone analogues of uniflorol as anti-leishmanial agents

scientific article published on 20 March 2020

Targeted delivery of paromomycin in murine infectious diseases through association to nano lipid systems

scientific article published on 11 July 2015

The cytosolic tryparedoxin of Leishmania infantum is essential for parasite survival

scientific article

Thiol Peroxidases of Trypanosomatids

Tryparedoxin Peroxidase of Leishmania donovani: Molecular Cloning, Heterologous Expression, Specificity, and Catalytic Mechanism

scientific article published in 2002

Tryparedoxin peroxidase of Leishmania donovani: molecular cloning, heterologous expression, specificity, and catalytic mechanism

scientific article published in January 2002

Two linked genes of Leishmania infantum encode tryparedoxins localised to cytosol and mitochondrion.

scientific article published in August 2004