List of works - Klaus Korn

A novel CDK7 inhibitor of the Pyrazolotriazine class exerts broad-spectrum antiviral activity at nanomolar concentrations.

scientific article

A reporter system for Epstein-Barr virus (EBV) lytic replication: anti-EBV activity of the broad anti-herpesviral drug artesunate.

scientific article published on 17 March 2011

BK viremia and polyomavirus nephropathy in 352 kidney transplants; risk factors and potential role of mTOR inhibition.

scientific article

Computational methods for the design of effective therapies against drug resistant HIV strains

scientific article

Delayed seroconversion and rapid onset of lymphoproliferative disease after transmission of human T-cell lymphotropic virus type 1 from a multiorgan donor

scientific article published on 15 August 2013

Differential effects of P-class versus other CpG oligodeoxynucleotide classes on the impaired innate immunity of plasmacytoid dendritic cells in HIV type 1 infection.

scientific article published in February 2010

Dual selection pressure by drugs and HLA class I-restricted immune responses on human immunodeficiency virus type 1 protease

scientific article published on 3 January 2007

Early mortality of brain cancer patients and its connection to cytomegalovirus reactivation during radiochemotherapy

scientific article published on 14 February 2020

Elevated CD40 ligand silences α interferon production in an HIV-related immune reconstitution inflammatory syndrome.

scientific article published in January 2013

Epigenetic analysis of HIV-1 proviral genomes from infected individuals: predominance of unmethylated CpG's.

scientific article

Estimates and Determinants of SARS-Cov-2 Seroprevalence and Infection Fatality Ratio Using Latent Class Analysis: The Population-Based Tirschenreuth Study in the Hardest-Hit German County in Spring 2020

scientific article published in 2021

European guidelines on the clinical management of HIV-1 tropism testing

scientific article published on 21 March 2011

HIV-1 seroreversion following antiretroviral therapy in an HIV-infected child initially presenting with acquired immunodeficiency syndrome

scientific article published on 01 January 2010

HIV-1 subtype distribution and its demographic determinants in newly diagnosed patients in Europe suggest highly compartmentalized epidemics

scientific article published on 14 January 2013

HIV-GRADE: a publicly available, rules-based drug resistance interpretation algorithm integrating bioinformatic knowledge

scientific article published on 24 January 2012

HTLV-1 associated myelopathy after renal transplantation

scientific article published on 9 October 2015

Images in clinical medicine. Cowpox infection

scientific article published on 01 January 2003

Impaired plasmacytoid dendritic cell innate immune responses in patients with herpes virus-associated acute retinal necrosis.

scientific article

Increase in transmitted resistance to non-nucleoside reverse transcriptase inhibitors among newly diagnosed HIV-1 infections in Europe

scientific article

Influence of major HIV-1 protease inhibitor resistance mutations on CTL recognition

scientific article published on 01 February 2011

Limited cross-border infections in patients newly diagnosed with HIV in Europe

scientific article published on 3 April 2013

Low level of cross-resistance to amprenavir (141W94) in samples from patients pretreated with other protease inhibitors

scientific article

Molecular typing of enteroviruses: current status and future requirements. The European Union Concerted Action on Virus Meningitis and Encephalitis

scientific article

Multicenter quality assessment of PCR methods for detection of enteroviruses.

scientific article

No evidence for persistence of multidrug-resistant viral strains after a 7-month treatment interruption in an HIV-1-infected individual

scientific article published on 01 October 2002

Optimized protocol for detection of HIV-1 drug mutations in patients with low viral load

article

Patterns of transmitted HIV drug resistance in Europe vary by risk group

scientific article (publication date: 2014)

Prediction of abacavir resistance from genotypic data: impact of zidovudine and lamivudine resistance in vitro and in vivo

scientific article

Prevalence of drug-resistant HIV-1 variants in untreated individuals in Europe: implications for clinical management

scientific article published on 15 August 2005

Prevalence of key resistance mutations K65R, K103N, and M184V as minority HIV-1 variants in chronically HIV-1 infected, treatment-naïve patients

scientific article published on 4 November 2010

Safety and efficacy of a NRTI-sparing HAART regimen of efavirenz and lopinavir/ritonavir in HIV-1-infected children.

scientific article

Sensitivity of human herpesvirus 6 and other human herpesviruses to the broad-spectrum antiinfective drug artesunate.

scientific article published on 4 June 2009

Seroreversion in vertically HIV-1-infected children treated early and efficiently: rule or exception?

scientific article published on 01 November 2010

Single-point mutations causing more than 100-fold underestimation of human immunodeficiency virus type 1 (HIV-1) load with the Cobas TaqMan HIV-1 real-time PCR assay.

scientific article published on 04 February 2009

Tenofovir resistance and resensitization

scientific article published on November 2003

The Calculated Genetic Barrier for Antiretroviral Drug Resistance Substitutions Is Largely Similar for Different HIV-1 Subtypes

article

The N-Terminus of the HIV-1 p6 Gag Protein Regulates Susceptibility to Degradation by IDE

article

Time Trend in SARS-CoV-2 Seropositivity, Surveillance Detection- and Infection Fatality Ratio until Spring 2021 in the Tirschenreuth County—Results from a Population-Based Longitudinal Study in Germany

scientific article published in 2022

Tracing the HIV-1 subtype B mobility in Europe: a phylogeographic approach

scientific article published on 20 May 2009

Transmission of drug-resistant HIV-1 is stabilizing in Europe

scientific article published in November 2009

Treatment-associated polymorphisms in protease are significantly associated with higher viral load and lower CD4 count in newly diagnosed drug-naive HIV-1 infected patients

scientific article

List of works by Klaus Korn

A novel CDK7 inhibitor of the Pyrazolotriazine class exerts broad-spectrum antiviral activity at nanomolar concentrations.

A reporter system for Epstein-Barr virus (EBV) lytic replication: anti-EBV activity of the broad anti-herpesviral drug artesunate.

BK viremia and polyomavirus nephropathy in 352 kidney transplants; risk factors and potential role of mTOR inhibition.

Computational methods for the design of effective therapies against drug resistant HIV strains

Delayed seroconversion and rapid onset of lymphoproliferative disease after transmission of human T-cell lymphotropic virus type 1 from a multiorgan donor

Differential effects of P-class versus other CpG oligodeoxynucleotide classes on the impaired innate immunity of plasmacytoid dendritic cells in HIV type 1 infection.

Dual selection pressure by drugs and HLA class I-restricted immune responses on human immunodeficiency virus type 1 protease

Early mortality of brain cancer patients and its connection to cytomegalovirus reactivation during radiochemotherapy

Elevated CD40 ligand silences α interferon production in an HIV-related immune reconstitution inflammatory syndrome.

Epigenetic analysis of HIV-1 proviral genomes from infected individuals: predominance of unmethylated CpG's.

Estimates and Determinants of SARS-Cov-2 Seroprevalence and Infection Fatality Ratio Using Latent Class Analysis: The Population-Based Tirschenreuth Study in the Hardest-Hit German County in Spring 2020

European guidelines on the clinical management of HIV-1 tropism testing

HIV-1 seroreversion following antiretroviral therapy in an HIV-infected child initially presenting with acquired immunodeficiency syndrome

HIV-1 subtype distribution and its demographic determinants in newly diagnosed patients in Europe suggest highly compartmentalized epidemics

HIV-GRADE: a publicly available, rules-based drug resistance interpretation algorithm integrating bioinformatic knowledge

HTLV-1 associated myelopathy after renal transplantation

Images in clinical medicine. Cowpox infection

Impaired plasmacytoid dendritic cell innate immune responses in patients with herpes virus-associated acute retinal necrosis.

Increase in transmitted resistance to non-nucleoside reverse transcriptase inhibitors among newly diagnosed HIV-1 infections in Europe

Influence of major HIV-1 protease inhibitor resistance mutations on CTL recognition

Limited cross-border infections in patients newly diagnosed with HIV in Europe

Low level of cross-resistance to amprenavir (141W94) in samples from patients pretreated with other protease inhibitors

Molecular typing of enteroviruses: current status and future requirements. The European Union Concerted Action on Virus Meningitis and Encephalitis

Multicenter quality assessment of PCR methods for detection of enteroviruses.

No evidence for persistence of multidrug-resistant viral strains after a 7-month treatment interruption in an HIV-1-infected individual

Optimized protocol for detection of HIV-1 drug mutations in patients with low viral load

Patterns of transmitted HIV drug resistance in Europe vary by risk group

Prediction of abacavir resistance from genotypic data: impact of zidovudine and lamivudine resistance in vitro and in vivo

Prevalence of drug-resistant HIV-1 variants in untreated individuals in Europe: implications for clinical management

Prevalence of key resistance mutations K65R, K103N, and M184V as minority HIV-1 variants in chronically HIV-1 infected, treatment-naïve patients

Safety and efficacy of a NRTI-sparing HAART regimen of efavirenz and lopinavir/ritonavir in HIV-1-infected children.

Sensitivity of human herpesvirus 6 and other human herpesviruses to the broad-spectrum antiinfective drug artesunate.

Seroreversion in vertically HIV-1-infected children treated early and efficiently: rule or exception?

Single-point mutations causing more than 100-fold underestimation of human immunodeficiency virus type 1 (HIV-1) load with the Cobas TaqMan HIV-1 real-time PCR assay.

Tenofovir resistance and resensitization

The Calculated Genetic Barrier for Antiretroviral Drug Resistance Substitutions Is Largely Similar for Different HIV-1 Subtypes

The N-Terminus of the HIV-1 p6 Gag Protein Regulates Susceptibility to Degradation by IDE

Time Trend in SARS-CoV-2 Seropositivity, Surveillance Detection- and Infection Fatality Ratio until Spring 2021 in the Tirschenreuth County—Results from a Population-Based Longitudinal Study in Germany

Tracing the HIV-1 subtype B mobility in Europe: a phylogeographic approach

Transmission of drug-resistant HIV-1 is stabilizing in Europe

Treatment-associated polymorphisms in protease are significantly associated with higher viral load and lower CD4 count in newly diagnosed drug-naive HIV-1 infected patients