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List of works by Deborah Mash

A Common DIO2 Polymorphism And Alzheimer's Disease Dementia in African And European Americans.

scientific article published on 22 February 2018

A genomic pathway approach to a complex disease: axon guidance and Parkinson disease

scientific article

A review of brain biorepository management and operations

article

ATP13A2 variability in Parkinson disease.

scientific article published on March 2009

Absence of C9ORF72 expanded or intermediate repeats in autopsy-confirmed Parkinson's disease

scientific article

Adaptive increase in D3 dopamine receptors in the brain reward circuits of human cocaine fatalities

scientific article

Alpha synuclein protein levels are increased in serum from recently abstinent cocaine abusers

scientific article published on 4 December 2007

Alpha-synuclein aggregation and its relation to neurodegenerative diseases

scientific article published in April 2005

Altered Dopamine Synaptic Markers in Postmortem Brain of Obese Subjects.

scientific article published on 3 August 2017

Alzheimer disease (AD) specific transcription, DNA methylation and splicing in twenty AD associated loci

scientific article published on 21 May 2015

An evaluation of the impact of MAPT, SNCA and APOE on the burden of Alzheimer's and Lewy body pathology

scientific article published on 30 January 2012

Assessment of stress markers in restrained individuals following physical stress with and without sham CED activation

scientific article published on 26 June 2020

Assessment of the Association of D2 Dopamine Receptor Gene and Reported Allele Frequencies With Alcohol Use Disorders: A Systematic Review and Meta-analysis

scientific article published on 01 November 2019

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Beyond Guam: the cyanobacteria/BMAA hypothesis of the cause of ALS and other neurodegenerative diseases

scientific article

BisQC: an operational pipeline for multiplexed bisulfite sequencing

scientific article

Brain CYP2E1 is induced by nicotine and ethanol in rat and is higher in smokers and alcoholics.

scientific article

Brain biomarkers for identifying excited delirium as a cause of sudden death

scientific article published on 21 June 2009

Breaking the cycle of opioid use disorder with Ibogaine

scientific article published on 7 December 2017

CNVs in neurodevelopmental disorders

scientific article published on July 2015

CYP3A5 Mediates Effects of Cocaine on Human Neocorticogenesis: Studies using an In Vitro 3D Self-Organized hPSC Model with a Single Cortex-Like Unit.

scientific article published on 18 August 2016

Cause, seasonality of death and co-morbidities in progressive supranuclear palsy (PSP).

scientific article published on 9 September 2005

Causes of death in multiple system atrophy

scientific article published on March 2007

Cerebral uptake and protein incorporation of cyanobacterial toxin β-N-methylamino-L-alanine

scientific article published in October 2013

Cholinergic nucleus basalis tauopathy emerges early in the aging-MCI-AD continuum.

scientific article published on June 2004

Clinical Heterogeneity of the LRRK2 G2019S Mutation

Cocaine abuse elevates alpha-synuclein and dopamine transporter levels in the human striatum

scientific article published in September 2005

Cocaine abusers have an overexpression of alpha-synuclein in dopamine neurons.

scientific article published in April 2003

Cocaine promotes primary human astrocyte proliferation via JNK-dependent up-regulation of cyclin A2.

scientific article published in November 2016

Cocaine-induced alterations in nucleus accumbens ionotropic glutamate receptor subunits in human and non-human primates

scientific article published on December 2005

Cocaine-related DNA methylation in caudate neurons alters 3D chromatin structure of the IRXA gene cluster

scientific article published on 12 October 2020

Commentary on: Johnson MM, David JA, Michelhaugh SK, Schmidt CJ, Bannon MJ. Increased heat shock protein 70 gene expression in the brains of cocaine-related fatalities may be reflective of postdrug survival and intervention rather than excited delir

scientific article published in March 2013

Common human 5' dopamine transporter (SLC6A3) haplotypes yield varying expression levels in vivo

scientific article

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

scientific article

Correction: Somatic mtDNA Mutation Spectra in the Aging Human Putamen.

scientific article published on 24 December 2013

Correlating human and animal studies of cocaine abuse and gene expression.

scientific article published on October 2008

Corrigendum to "Determinants of denervation-independent depletion of putamen dopamine in Parkinson's disease and multiple system atrophy" [Parkinsonism Relat. Disord. 35 (2017) 88-91]

scientific article published on 06 April 2017

Cortical and amygdalar Lewy body burden in Parkinson's disease patients with visual hallucinations

scientific article published on 20 December 2005

Criteria for the interpretation of cocaine levels in human biological samples and their relation to the cause of death

scientific article published on March 2004

Cyanobacterial Neurotoxin BMAA and Mercury in Sharks

scientific article

Cyanobacterial Neurotoxin β-N-Methylamino-L-alanine (BMAA) in Shark Fins ⬇️

scientific article published on February 21, 2012

Cyanobacterial blooms and the occurrence of the neurotoxin, beta-N-methylamino-l-alanine (BMAA), in South Florida aquatic food webs ⬇️

scientific article published on September 1, 2010

Cyanobacterial neurotoxin BMAA and brain pathology in stranded dolphins

scientific article published on 20 March 2019

DNA Methylation Dynamics and Cocaine in the Brain: Progress and Prospects

scientific article

Decreased expression of the transcription factor NURR1 in dopamine neurons of cocaine abusers

scientific article

Decreased vesicular storage and aldehyde dehydrogenase activity in multiple system atrophy

scientific article published on 20 March 2015

Deficient vesicular storage: A common theme in catecholaminergic neurodegeneration.

scientific article

Determinants of buildup of the toxic dopamine metabolite DOPAL in Parkinson's disease

scientific article

Determinants of denervation-independent depletion of putamen dopamine in Parkinson's disease and multiple system atrophy.

scientific article published on 15 December 2016

Dietary exposure to an environmental toxin triggers neurofibrillary tangles and amyloid deposits in the brain

scientific article

Differential expression of human COMT alleles in brain and lymphoblasts detected by RT-coupled 5' nuclease assay

scientific article

Disparities in death certificates of Parkinson's disease patients: a report from a population of brain donors

scientific article published in October 2006

Do vervets and macaques respond differently to BMAA?

scientific article published on 28 April 2016

Does cigarette smoking provide clinically significant neuroprotection among patients diagnosed with Parkinson's disease?

scientific article published on 01 May 2005

Dopamine transport function is elevated in cocaine users

scientific article

Dopaminergic innervation of the human striatum in Parkinson's disease

scientific article published on 01 January 2007

Dynamics of hippocampal neurogenesis in adult humans

scientific article

EXCITATION study: Unexplained in-custody deaths: Evaluating biomarkers of stress and agitation

scientific article published on 21 June 2019

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study

scientific article

Environmental neurotoxins β-N-methylamino-l-alanine (BMAA) and mercury in shark cartilage dietary supplements

scientific article published on 19 April 2014

Excited Delirium Syndrome (ExDS): Defining Based on a Review of the Literature ⬇️

scientific article published on March 25, 2011

Excited Delirium and Sudden Death: A Syndromal Disorder at the Extreme End of the Neuropsychiatric Continuum

scientific article

Expression of alpha-synuclein mRNA in Parkinson's disease

scientific article published in May 2007

FGF20 and Parkinson's disease: no evidence of association or pathogenicity via alpha-synuclein expression

scientific article

Family history of dementia: dementia with lewy bodies and dementia in Parkinson's disease

scientific article published in January 2006

First-in-class thyrotropin-releasing hormone (TRH)-based compound binds to a pharmacologically distinct TRH receptor subtype in human brain and is effective in neurodegenerative models

scientific article published on 30 September 2014

GABAergic gene expression in postmortem hippocampus from alcoholics and cocaine addicts; corresponding findings in alcohol-naïve P and NP rats

scientific article

GCH1 expression in human cerebellum from healthy individuals is not gender dependent

scientific article published on 30 June 2009

Galanin receptor over-expression within the amygdala in early Alzheimer's disease: an in vitro autoradiographic analysis

scientific article published in July 2002

Gene Network Dysregulation in Dorsolateral Prefrontal Cortex Neurons of Humans with Cocaine Use Disorder

scientific article

Gene expression in human hippocampus from cocaine abusers identifies genes which regulate extracellular matrix remodeling

scientific article

Generation of disease-specific autopsy-confirmed iPSCs lines from postmortem isolated Peripheral Blood Mononuclear Cells

scientific article published on 4 November 2016

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

Genetic variation in human NPY expression affects stress response and emotion

scientific article published on 02 April 2008

Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias

scientific article

Genome-wide brain DNA methylation analysis suggests epigenetic reprogramming in Parkinson disease

scientific article published on 24 June 2019

Glucocerebrosidase mutations in diffuse Lewy body disease

scientific article

Glucosidase-beta variations and Lewy body disorders

scientific article

Hallucinations in multiple system atrophy

scientific article published on 13 October 2006

Human BDNF isoforms are differentially expressed in cocaine addicts and are sorted to the regulated secretory pathway independent of the Met66 substitution

scientific article

Human Serotonin Transporter Coding Variation Establishes Conformational Bias with Functional Consequences

scientific article published on 05 February 2019

Hypothesizing Las Vegas and Sutherland Springs Mass Shooters Suffer from Reward Deficiency Syndrome: "Born Bad"

scientific article published on 30 December 2017

Ibogaine Detoxification Transitions Opioid and Cocaine Abusers Between Dependence and Abstinence: Clinical Observations and Treatment Outcomes.

scientific article published on 5 June 2018

Ibogaine analogues. Synthesis and preliminary pharmacological evaluation of 7-heteroaryl-2-azabicyclo[2.2.2]oct-7-enes

scientific article published on 01 March 2003

Identification of the sites of tau hyperphosphorylation and activation of tau kinases in synucleinopathies and Alzheimer's diseases

scientific article

Identifying consensus disease pathways in Parkinson's disease using an integrative systems biology approach

scientific article

Induction of the drug metabolizing enzyme CYP2D in monkey brain by chronic nicotine treatment

scientific article published on 19 July 2008

Insular pathology in Parkinson's disease patients with orthostatic hypotension

scientific article published on 7 September 2006

Integrated whole transcriptome and DNA methylation analysis identifies gene networks specific to late-onset Alzheimer's disease

scientific article

Intronic Polymorphisms Affecting Alternative Splicing of Human Dopamine D2 Receptor Are Associated with Cocaine Abuse ⬇️

scientific article published on December 8, 2010

Localization of muscarinic receptor subtypes in brain stem areas regulating sleep

scientific article published in August 1994

Locus coeruleus neurofibrillary degeneration in aging, mild cognitive impairment and early Alzheimer's disease

scientific article published on 29 March 2006

Lrrk2 and Lewy body disease

scientific article published in February 2006

MDMA self-administration in rats: acquisition, progressive ratio responding and serotonin transporter binding

scientific article

Markers for dopaminergic neurotransmission in the cerebellum in normal individuals and patients with Parkinson's disease examined by RT-PCR.

scientific article published in November 2003

Medication Development of Ibogaine as a Pharmacotherapy for Drug Dependencea

Melatonin MT1 and MT2 receptor expression in Parkinson's disease

scientific article

Molecular profiling of midbrain dopamine regions in cocaine overdose victims ⬇️

scientific article published on May 1, 2003

Multiregional gene expression profiling identifies MRPS6 as a possible candidate gene for Parkinson's disease

scientific article published in January 2006

National Association of Medical Examiners position paper on the certification of cocaine-related deaths

scientific article published in March 2004

Natural history of progressive supranuclear palsy: a clinicopathologic study from a population of brain donors

scientific article published on 05 July 2005

Neurofibrillary tangles, amyloid, and memory in aging and mild cognitive impairment

scientific article

Nicotinic α5 receptor subunit mRNA expression is associated with distant 5' upstream polymorphisms

scientific article

Norepinephrine transporter immunoblotting and radioligand binding in cocaine abusers

scientific article

Noribogaine is a G-protein biased κ-opioid receptor agonist

scientific article

Noribogaine reduces nicotine self-administration in rats

scientific article

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

scientific article

Oral noribogaine shows high brain uptake and anti-withdrawal effects not associated with place preference in rodents.

scientific article published on 4 April 2016

PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease

scientific article

Phenotypic associations of tau and ApoE in Parkinson's disease

scientific article published on 3 January 2007

Prevalent polymorphism in thyroid hormone-activating enzyme leaves a genetic fingerprint that underlies associated clinical syndromes

scientific article

Quantitative PCR-based screening of alpha-synuclein multiplication in multiple system atrophy

scientific article published on 8 February 2007

RIG-1 receptor expression in the pathology of Alzheimer's disease

scientific article published on 02 April 2014

RNA sequencing of transcriptomes in human brain regions: protein-coding and non-coding RNAs, isoforms and alleles

scientific article published on 23 November 2015

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

scientific article

Rarity of the Alzheimer disease-protective APP A673T variant in the United States

scientific article

Reading LINEs within the cocaine addicted brain

scientific article

Reduced LRRK2 in association with retromer dysfunction in post-mortem brain tissue from LRRK2 mutation carriers

scientific article published on 14 December 2017

Regional and cellular expression of CYP2D6 in human brain: higher levels in alcoholics.

scientific article

Repeat expansions in the C9ORF72 gene contribute to Alzheimer's disease in Caucasians ⬇️

scientific article published on October 27, 2012

Response of rats to low levels of sarin.

scientific article published in October 2002

Restriction Enzyme Based Enriched L1Hs Sequencing (REBELseq): A Scalable Technique for Detection of Ta Subfamily L1Hs in the Human Genome

scientific article published on 04 March 2020

Robust single-cell DNA methylome profiling with snmC-seq2

scientific article published in Nature Communications

Smoking, alcoholism and genetic polymorphisms alter CYP2B6 levels in human brain

scientific article

Somatic mtDNA mutation spectra in the aging human putamen

scientific article

Species and cell-type properties of classically defined human and rodent neurons and glia

scientific article published on 15 October 2018

Substance-specific and shared transcription and epigenetic changes in the human hippocampus chronically exposed to cocaine and alcohol

scientific article

THE HUMAN BRAINOME: HUMAN BRAIN GENOME, TRANSCRIPTOME, AND PROTEOME INTEGRATION

The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target

The natural non-protein amino acid N-β-methylamino-L-alanine (BMAA) is incorporated into protein during synthesis

scientific article published on 6 August 2014

The neurochemical mechanism of rebound psychosis in Parkinson's disease

scientific article published in April 2005

The neuroprotective enzyme CYP2D6 increases in the brain with age and is lower in Parkinson's disease patients.

scientific article

The rhesus macaque is three times as diverse but more closely equivalent in damaging coding variation as compared to the human

scientific article (publication date: 29 June 2012)

Thinning of the arterial media layer as a possible preclinical stage in HIV vasculopathy: a pilot study

scientific article published on 22 December 2011

Visual hallucinations in progressive supranuclear palsy

scientific article published on 01 January 2005

Vitamin D receptor and Alzheimer's disease: a genetic and functional study ⬇️

scientific article published on February 4, 2012

Zhou et al. reply

scientific article published in Nature

l-Serine Reduces Spinal Cord Pathology in a Vervet Model of Preclinical ALS/MND

scientific article published on 01 April 2020

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