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List of works by Javier Espino

A jerte valley cherry-based product as a supply of tryptophan.

scientific article published on 16 April 2012

A nutraceutical product based on Jerte Valley cherries improves sleep and augments the antioxidant status in humans

Autophagy-related proteins are functionally active in human spermatozoa and may be involved in the regulation of cell survival and motility.

scientific article published on 16 September 2016

Bioavailability of Bioactive Molecules from Olive Leaf Extracts and its Functional Value.

scientific article published on 3 May 2016

Caspase-3 and -9 are activated in human myeloid HL-60 cells by calcium signal.

scientific article

Chemical composition and bioactivity of essential oils from flower and fruit of Thymbra capitata and Thymus species.

scientific article published on 10 April 2017

Exogenous melatonin supplementation prevents oxidative stress-evoked DNA damage in human spermatozoa.

scientific article

Extracellular heat shock proteins protect U937 cells from H2O2-induced apoptotic cell death.

scientific article published on 3 November 2015

FMLP-, thapsigargin-, and H2O2-evoked changes in intracellular free calcium concentration in lymphocytes and neutrophils of type 2 diabetic patients

scientific article published on 15 November 2013

High endogenous melatonin concentrations enhance sperm quality and short-term in vitro exposure to melatonin improves aspects of sperm motility

scientific article published on 21 October 2010

Impact of Melatonin Supplementation in Women with Unexplained Infertility Undergoing Fertility Treatment

scientific article published on 23 August 2019

Jerte Valley cherry-based product modulates serum inflammatory markers in rats and ringdoves

MICU3 is a tissue-specific enhancer of mitochondrial calcium uptake.

scientific article published on 3 May 2018

Melatonin and tryptophan affect the activity-rest rhythm, core and peripheral temperatures, and interleukin levels in the ringdove: changes with age

scientific article published on 10 February 2009

Melatonin as a potential tool against oxidative damage and apoptosis in ejaculated human spermatozoa.

scientific article published on 12 February 2010

Melatonin counteracts alterations in oxidative metabolism and cell viability induced by intracellular calcium overload in human leucocytes: changes with age.

scientific article

Melatonin enhances hydrogen peroxide-induced apoptosis in human promyelocytic leukaemia HL-60 cells.

scientific article

Melatonin increases the effect of 5-fluorouracil-based chemotherapy in human colorectal adenocarcinoma cells in vitro.

scientific article

Melatonin induces mitochondrial-mediated apoptosis in human myeloid HL-60 cells

scientific article

Melatonin is able to delay endoplasmic reticulum stress-induced apoptosis in leukocytes from elderly humans

scientific article published on 18 November 2010

Melatonin potentiates chemotherapy-induced cytotoxicity and apoptosis in rat pancreatic tumor cells

scientific article published on 31 January 2012

Melatonin protects human spermatozoa from apoptosis via melatonin receptor– and extracellular signal–regulated kinase-mediated pathways

scientific article published on 16 April 2011

Melatonin reduces apoptosis induced by calcium signaling in human leukocytes: Evidence for the involvement of mitochondria and Bax activation

scientific article published on 4 February 2010

Melatonin sensitizes human cervical cancer HeLa cells to cisplatin-induced cytotoxicity and apoptosis: effects on oxidative stress and DNA fragmentation

scientific article published on 14 October 2015

Oxidative stress and immunosenescence: therapeutic effects of melatonin

scientific article published on 31 December 2012

Participation of MT3 melatonin receptors in the synergistic effect of melatonin on cytotoxic and apoptotic actions evoked by chemotherapeutics

scientific article published on 27 September 2017

Plant Phenolics: Bioavailability as a Key Determinant of Their Potential Health-Promoting Applications

scientific article published on 12 December 2020

Pro-oxidant effect of melatonin in tumour leucocytes: relation with its cytotoxic and pro-apoptotic effects

scientific article published on January 2011

Protective effect of melatonin against human leukocyte apoptosis induced by intracellular calcium overload: relation with its antioxidant actions

scientific article published on 07 April 2011

Reduced levels of intracellular calcium releasing in spermatozoa from asthenozoospermic patients

scientific article published on 6 February 2009

Relationship between caspase activity and apoptotic markers in human sperm in response to hydrogen peroxide and progesterone

scientific article

Role of melatonin on diabetes-related metabolic disorders

scientific article

Selenium modulates oxidative stress-induced cell apoptosis in human myeloid HL-60 cells through regulation of calcium release and caspase-3 and -9 activities.

scientific article

Systemic inflammatory load in young and old ringdoves is modulated by consumption of a Jerte Valley cherry-based product.

scientific article

Tempranillo-derived grape seed extract induces apoptotic cell death and cell growth arrest in human promyelocytic leukemia HL-60 cells.

scientific article published on 16 October 2013

The MCU complex in cell death

scientific article published on 25 August 2017

The consumption of a Jerte Valley cherry product in humans enhances mood, and increases 5-hydroxyindoleacetic acid but reduces cortisol levels in urine.

scientific article

The correlation between urinary 5-hydroxyindoleacetic acid and sperm quality in infertile men and rotating shift workers.

scientific article

The inhibition of TNF-α-induced leucocyte apoptosis by melatonin involves membrane receptor MT1/MT2 interaction.

scientific article

Zinc(II) complexes with novel 1,3-thiazine/pyrazole derivative ligands: Synthesis, structural characterization and effect of coordination on the phagocytic activity of human neutrophils

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