List of works - Margareta Törnqvist

A new general pathway for synthesis of reference compounds of N-terminal valine-isocyanate adducts

scientific article published in March 2010

A new modified Edman procedure for analysis of N-terminal valine adducts in hemoglobin by LC-MS/MS.

scientific article published on 24 March 2010

Acrylamide exposure measured by food frequency questionnaire and hemoglobin adduct levels and prostate cancer risk in the Cancer of the Prostate in Sweden Study

scientific article

Acrylamide in food: the discovery and its implications: a historical perspective

scientific article

Adductomic Screening of Hemoglobin Adducts and Monitoring of Micronuclei in School-Age Children.

scientific article published on 11 April 2017

Alcohol influence on acrylamide to glycidamide metabolism assessed with hemoglobin-adducts and questionnaire data

scientific article

An Adductomic Approach to Identify Electrophiles In Vivo

scientific article published on 27 November 2016

Analysis of acrylamide, a carcinogen formed in heated foodstuffs

scientific article

Analysis of hemoglobin adducts from acrylamide, glycidamide, and ethylene oxide in paired mother/cord blood samples from Denmark

scientific article published on 15 September 2011

Applicability of a modified Edman procedure for measurement of protein adducts: mechanisms of formation and degradation of phenylthiohydantoins

scientific article

Approach for cancer risk estimation of acrylamide in food on the basis of animal cancer tests and in vivo dosimetry

scientific article published on 15 July 2008

Birth weight, head circumference, and prenatal exposure to acrylamide from maternal diet: the European prospective mother-child study (NewGeneris).

scientific article published on 23 September 2012

Both replication bypass fidelity and repair efficiency influence the yield of mutations per target dose in intact mammalian cells induced by benzo[a]pyrene-diol-epoxide and dibenzo[a,l]pyrene-diol-epoxide

scientific article

Bulky dna adducts in cord blood, maternal fruit-and-vegetable consumption, and birth weight in a European mother-child study (NewGeneris).

scientific article published on 23 July 2013

Cancer risk assessment, indicators, and guidelines for polycyclic aromatic hydrocarbons in the ambient air

scientific article

Characterization of a Hemoglobin Adduct from Ethyl Vinyl Ketone Detected in Human Blood Samples.

scientific article published on 8 October 2015

Characterization of alkyl-cobalamins formed on trapping of epoxide metabolites of 1,3-butadiene

scientific article published in May 2004

Characterization of glycidol-hemoglobin adducts as biomarkers of exposure and in vivo dose

scientific article published on 25 January 2014

Chronic intake of potato chips in humans increases the production of reactive oxygen radicals by leukocytes and increases plasma C-reactive protein: a pilot study

scientific article

Cob(I)alamin for trapping butadiene epoxides in metabolism with rat S9 and for determining associated kinetic parameters

scientific article published in September 2009

Conditions for sample preparation and quantitative HPLC/MS-MS analysis of bulky adducts to serum albumin with diolepoxides of polycyclic aromatic hydrocarbons as models.

scientific article published on 4 January 2014

DNA repair and replication influence the number of mutations per adduct of polycyclic aromatic hydrocarbons in mammalian cells

scientific article published on 2 July 2011

Dietary acrylamide intake during pregnancy and fetal growth-results from the Norwegian mother and child cohort study (MoBa)

scientific article published on 29 November 2012

Differences in hemoglobin adduct levels of acrylamide in the general population with respect to dietary intake, smoking habits and gender.

scientific article published on February 2005

Differences in micronucleus frequency and acrylamide adduct levels with hemoglobin between vegetarians and non-vegetarians.

scientific article

Differences in the frequency of micronucleated erythrocytes in humans in relation to consumption of fried carbohydrate-rich food

scientific article published on 7 April 2008

Discovery of Novel N-(4-Hydroxybenzyl)valine Hemoglobin Adducts in Human Blood

scientific article published on 19 November 2018

Effects on the peripheral nervous system of tunnel workers exposed to acrylamide and N-methylolacrylamide.

scientific article published in February 2004

Evaluation of cancer tests of 1,3-butadiene using internal dose, genotoxic potency, and a multiplicative risk model

scientific article published in October 2008

Evaluation of molecularly imprinted solid-phase extraction for a 1,2:3,4-diepoxybutane adduct to valine

scientific article

Evaluation of retinol binding protein 4 and carbamoylated haemoglobin as potential renal toxicity biomarkers in adult mice treated with (177)Lu-octreotate

scientific article published on 31 October 2014

Evidence for phosphate adducts in DNA from mice treated with 4-(N-Methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

scientific article

Factors that influence the acrylamide content of heated foods

scientific article published in January 2005

Global gene expression analysis in cord blood reveals gender-specific differences in response to carcinogenic exposure in utero

scientific article published on 9 August 2012

Hemoglobin adduct levels in rat and mouse treated with 1,2:3,4-diepoxybutane

scientific article

Hemoglobin adducts and micronuclei in rodents after treatment with isoprene monoxide or butadiene monoxide

scientific article published in August 2005

Hemoglobin adducts and micronucleus frequencies in mouse and rat after acrylamide or N-methylolacrylamide treatment

scientific article

Hemoglobin adducts as a measure of variations in exposure to acrylamide in food and comparison to questionnaire data

scientific article

Hemoglobin adducts from glycidamide: acetonization of hydrophilic groups for reproducible gas chromatography/tandem mass spectrometric analysis

scientific article published in January 2003

In vitro studies of the influence of certain enzymes on the detoxification of acrylamide and glycidamide in blood

scientific article published in January 2005

In vitro studies of the influence of glutathione transferases and epoxide hydrolase on the detoxification of acrylamide and glycidamide in blood

scientific article published in February 2005

In vivo doses of butadiene epoxides as estimated from in vitro enzyme kinetics by using cob(I)alamin and measured hemoglobin adducts: an inter-species extrapolation approach

scientific article published on 5 November 2014

Induction of micronuclei in mouse and rat by glycidamide, genotoxic metabolite of acrylamide

scientific article

Interaction of benzo[a]pyrene diol epoxide isomers with human serum albumin: Site specific characterisation of adducts and associated kinetics

scientific article

Internal Doses of Glycidol in Children and Estimation of Associated Cancer Risk

article

Internal doses of acrylamide and glycidamide in mice fed diets with low acrylamide contents

scientific article published in August 2008

Investigations of Factors That Influence the Acrylamide Content of Heated Foodstuffs ⬇️

scientific article published on November 19, 2003

LC-MS/MS screening strategy for unknown adducts to N-terminal valine in hemoglobin applied to smokers and nonsmokers

scientific article published on 6 November 2014

Maternal diet during pregnancy and micronuclei frequency in peripheral blood T lymphocytes in mothers and newborns (Rhea cohort, Crete).

scientific article published on 21 September 2016

Measurement of micronuclei and internal dose in mice demonstrates that 3-monochloropropane-1,2-diol (3-MCPD) has no genotoxic potency in vivo

scientific article published on 13 September 2017

Methyl vinyl ketone--identification and quantification of adducts to N-terminal valine in human hemoglobin

scientific article published on 27 March 2010

Micronuclei in cord blood lymphocytes and associations with biomarkers of exposure to carcinogens and hormonally active factors, gene polymorphisms, and gene expression: the NewGeneris cohort ⬇️

scientific article

Parallelogram based approach for in vivo dose estimation of genotoxic metabolites in humans with relevance to reduction of animal experiments

scientific article published on 14 December 2017

Quantification of the mutagenic potency and repair of glycidol-induced DNA lesions.

scientific article published on 27 May 2016

Strategy for identifying unknown hemoglobin adducts using adductome LC-MS/MS data: Identification of adducts corresponding to acrylic acid, glyoxal, methylglyoxal, and 1-octen-3-one

scientific article

The genotoxic potency of glycidol established from micronucleus frequency and hemoglobin adduct levels in mice

scientific article published on 21 December 2016

Validation of a food frequency questionnaire measurement of dietary acrylamide intake using hemoglobin adducts of acrylamide and glycidamide

scientific article

Who knows whether acrylamide in food is hazardous to humans?

scientific article

List of works by Margareta Törnqvist

A new general pathway for synthesis of reference compounds of N-terminal valine-isocyanate adducts

A new modified Edman procedure for analysis of N-terminal valine adducts in hemoglobin by LC-MS/MS.

Acrylamide exposure measured by food frequency questionnaire and hemoglobin adduct levels and prostate cancer risk in the Cancer of the Prostate in Sweden Study

Acrylamide in food: the discovery and its implications: a historical perspective

Adductomic Screening of Hemoglobin Adducts and Monitoring of Micronuclei in School-Age Children.

Alcohol influence on acrylamide to glycidamide metabolism assessed with hemoglobin-adducts and questionnaire data

An Adductomic Approach to Identify Electrophiles In Vivo

Analysis of acrylamide, a carcinogen formed in heated foodstuffs

Analysis of hemoglobin adducts from acrylamide, glycidamide, and ethylene oxide in paired mother/cord blood samples from Denmark

Applicability of a modified Edman procedure for measurement of protein adducts: mechanisms of formation and degradation of phenylthiohydantoins

Approach for cancer risk estimation of acrylamide in food on the basis of animal cancer tests and in vivo dosimetry

Birth weight, head circumference, and prenatal exposure to acrylamide from maternal diet: the European prospective mother-child study (NewGeneris).

Both replication bypass fidelity and repair efficiency influence the yield of mutations per target dose in intact mammalian cells induced by benzo[a]pyrene-diol-epoxide and dibenzo[a,l]pyrene-diol-epoxide

Bulky dna adducts in cord blood, maternal fruit-and-vegetable consumption, and birth weight in a European mother-child study (NewGeneris).

Cancer risk assessment, indicators, and guidelines for polycyclic aromatic hydrocarbons in the ambient air

Characterization of a Hemoglobin Adduct from Ethyl Vinyl Ketone Detected in Human Blood Samples.

Characterization of alkyl-cobalamins formed on trapping of epoxide metabolites of 1,3-butadiene

Characterization of glycidol-hemoglobin adducts as biomarkers of exposure and in vivo dose

Chronic intake of potato chips in humans increases the production of reactive oxygen radicals by leukocytes and increases plasma C-reactive protein: a pilot study

Cob(I)alamin for trapping butadiene epoxides in metabolism with rat S9 and for determining associated kinetic parameters

Conditions for sample preparation and quantitative HPLC/MS-MS analysis of bulky adducts to serum albumin with diolepoxides of polycyclic aromatic hydrocarbons as models.

DNA repair and replication influence the number of mutations per adduct of polycyclic aromatic hydrocarbons in mammalian cells

Dietary acrylamide intake during pregnancy and fetal growth-results from the Norwegian mother and child cohort study (MoBa)

Differences in hemoglobin adduct levels of acrylamide in the general population with respect to dietary intake, smoking habits and gender.

Differences in micronucleus frequency and acrylamide adduct levels with hemoglobin between vegetarians and non-vegetarians.

Differences in the frequency of micronucleated erythrocytes in humans in relation to consumption of fried carbohydrate-rich food

Discovery of Novel N-(4-Hydroxybenzyl)valine Hemoglobin Adducts in Human Blood

Effects on the peripheral nervous system of tunnel workers exposed to acrylamide and N-methylolacrylamide.

Evaluation of cancer tests of 1,3-butadiene using internal dose, genotoxic potency, and a multiplicative risk model

Evaluation of molecularly imprinted solid-phase extraction for a 1,2:3,4-diepoxybutane adduct to valine

Evaluation of retinol binding protein 4 and carbamoylated haemoglobin as potential renal toxicity biomarkers in adult mice treated with (177)Lu-octreotate

Evidence for phosphate adducts in DNA from mice treated with 4-(N-Methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

Factors that influence the acrylamide content of heated foods

Global gene expression analysis in cord blood reveals gender-specific differences in response to carcinogenic exposure in utero

Hemoglobin adduct levels in rat and mouse treated with 1,2:3,4-diepoxybutane

Hemoglobin adducts and micronuclei in rodents after treatment with isoprene monoxide or butadiene monoxide

Hemoglobin adducts and micronucleus frequencies in mouse and rat after acrylamide or N-methylolacrylamide treatment

Hemoglobin adducts as a measure of variations in exposure to acrylamide in food and comparison to questionnaire data

Hemoglobin adducts from glycidamide: acetonization of hydrophilic groups for reproducible gas chromatography/tandem mass spectrometric analysis

In vitro studies of the influence of certain enzymes on the detoxification of acrylamide and glycidamide in blood

In vitro studies of the influence of glutathione transferases and epoxide hydrolase on the detoxification of acrylamide and glycidamide in blood

In vivo doses of butadiene epoxides as estimated from in vitro enzyme kinetics by using cob(I)alamin and measured hemoglobin adducts: an inter-species extrapolation approach

Induction of micronuclei in mouse and rat by glycidamide, genotoxic metabolite of acrylamide

Interaction of benzo[a]pyrene diol epoxide isomers with human serum albumin: Site specific characterisation of adducts and associated kinetics

Internal Doses of Glycidol in Children and Estimation of Associated Cancer Risk

Internal doses of acrylamide and glycidamide in mice fed diets with low acrylamide contents

Investigations of Factors That Influence the Acrylamide Content of Heated Foodstuffs ⬇️

LC-MS/MS screening strategy for unknown adducts to N-terminal valine in hemoglobin applied to smokers and nonsmokers

Maternal diet during pregnancy and micronuclei frequency in peripheral blood T lymphocytes in mothers and newborns (Rhea cohort, Crete).

Measurement of micronuclei and internal dose in mice demonstrates that 3-monochloropropane-1,2-diol (3-MCPD) has no genotoxic potency in vivo

Methyl vinyl ketone--identification and quantification of adducts to N-terminal valine in human hemoglobin

Micronuclei in cord blood lymphocytes and associations with biomarkers of exposure to carcinogens and hormonally active factors, gene polymorphisms, and gene expression: the NewGeneris cohort ⬇️

Parallelogram based approach for in vivo dose estimation of genotoxic metabolites in humans with relevance to reduction of animal experiments

Quantification of the mutagenic potency and repair of glycidol-induced DNA lesions.

Strategy for identifying unknown hemoglobin adducts using adductome LC-MS/MS data: Identification of adducts corresponding to acrylic acid, glyoxal, methylglyoxal, and 1-octen-3-one

The genotoxic potency of glycidol established from micronucleus frequency and hemoglobin adduct levels in mice

Validation of a food frequency questionnaire measurement of dietary acrylamide intake using hemoglobin adducts of acrylamide and glycidamide

Who knows whether acrylamide in food is hazardous to humans?