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List of works by James R Burke

A novel human disease with abnormal prion protein sensitive to protease

scientific article

APOE genotype-specific differences in human and mouse macrophage nitric oxide production

scientific article published in February 2004

Alternative ion channel splicing in mesial temporal lobe epilepsy and Alzheimer's disease

scientific article published on January 2007

Alzheimer's disease, anesthesia, and surgery: a clinically focused review

scientific article published on 26 September 2014

Amino Acid Sequence Requirements of Peptides That Inhibit Polyglutamine-Protein Aggregation and Cell Death

scientific article published on 01 November 2001

An international perspective on advanced neuroimaging: cometh the hour or ivory tower?

scientific article published on September 2011

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Cognitive performance and informant reports in the diagnosis of cognitive impairment and dementia in African Americans and whites

scientific article

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

scientific article

Disrupted spermine homeostasis: a novel mechanism in polyglutamine-mediated aggregation and cell death.

scientific article published on August 2004

Disruption of the toxic conformation of the expanded polyglutamine stretch leads to suppression of aggregate formation and cytotoxicity

scientific article published in May 2004

Duke Twins Study of Memory in Aging in the NAS-NRC Twin Registry

scientific article published in December 2006

Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.

scientific article published on August 2002

Effect of tissue transglutaminase on the solubility of proteins containing expanded polyglutamine repeats.

scientific article published in March 2004

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study

scientific article

Emotional enhancement of perceptual priming is preserved in aging and early-stage Alzheimer's disease

scientific article published on 25 February 2005

Event-related functional magnetic resonance imaging changes during relational retrieval in normal aging and amnestic mild cognitive impairment

scientific article published on 24 May 2012

Expanded polyglutamine domain proteins bind neurofilament and alter the neurofilament network.

scientific article published on February 1999

Expanded polyglutamine stretches form an 'aggresome'.

scientific article published in May 2002

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

Genome-wide scan of copy number variation in late-onset Alzheimer's disease

scientific article

Glyceraldehyde 3-phosphate dehydrogenase abnormality in metabolically stressed Huntington disease fibroblasts.

scientific article published in January 1998

Identification of chemical inhibitors to human tissue transglutaminase by screening existing drug libraries

scientific article

Impact of ¹⁸F-florbetapir PET imaging of β-amyloid neuritic plaque density on clinical decision-making

scientific article published on 14 May 2013

In vitro effects of polyglutamine tracts on Ca2+-dependent depolarization of rat and human mitochondria: relevance to Huntington's disease.

scientific article

Incidence of dementia and cognitive impairment, not dementia in the United States

scientific article

Inhibition of protein misfolding/aggregation using polyglutamine binding peptide QBP1 as a therapy for the polyglutamine diseases

scientific article published on July 2013

Inhibition of α-ketoglutarate-and pyruvate dehydrogenase complexes in E. coli by a glutathione S-transferase containing a pathological length poly-Q domain: A possible role of energy deficit in neurological diseases associated with poly-Q expansions

scientific article published on 01 January 1998

Job demands and dementia risk among male twin pairs

scientific article

Longitudinal magnetic resonance imaging vascular changes, apolipoprotein E genotype, and development of dementia in the neurocognitive outcomes of depression in the elderly study

scientific article

Metabolomic changes in autopsy-confirmed Alzheimer's disease

scientific article

Metabolomics in early Alzheimer's disease: identification of altered plasma sphingolipidome using shotgun lipidomics

scientific article

Methodology and preliminary results from the neurocognitive outcomes of depression in the elderly study.

scientific article

Midlife activity predicts risk of dementia in older male twin pairs

scientific article published on September 2008

Neuroanatomical correlates of malingered memory impairment: event-related fMRI of deception on a recognition memory task

scientific article

Neuropsychological predictors of dementia in late-life major depressive disorder

scientific article

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

scientific article

Optimization of a polyglutamine aggregation inhibitor peptide (QBP1) using a thioflavin T fluorescence assay

scientific article

Phage display screening for peptides that inhibit polyglutamine aggregation

scientific article published in January 2006

Phenotypic regional functional imaging patterns during memory encoding in mild cognitive impairment and Alzheimer's disease

scientific article published on 28 July 2012

Polyglutamine expansion inhibits respiration by increasing reactive oxygen species in isolated mitochondria

scientific article published on 13 January 2006

Postmortem delay has minimal effect on brain RNA integrity

scientific article published on December 2007

Pre-clinical cognitive phenotypes for Alzheimer disease: a latent profile approach

scientific article published on 27 September 2013

Prevalence of dementia in the United States: the aging, demographics, and memory study.

scientific article

Prevention of polyglutamine oligomerization and neurodegeneration by the peptide inhibitor QBP1 in Drosophila

scientific article

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

scientific article

Rarity of the Alzheimer disease-protective APP A673T variant in the United States

scientific article

Risk factors and preventive interventions for Alzheimer disease: state of the science

scientific article published on 09 May 2011

Screening for cognitive impairment: comparing the performance of four instruments in primary care

scientific article published on 30 May 2012

Sound induced vertigo: superior canal dehiscence resulting from blast exposure

scientific article

Specificity, sensitivity, and predictive value of apolipoprotein-E genotyping for sporadic Alzheimer's disease

scientific article published in July 1996

Stability of Diagnoses of Cognitive Impairment, Not Dementia in a Veterans Affairs Primary Care Population

scientific article

Systematic review: factors associated with risk for and possible prevention of cognitive decline in later life

scientific article published on 14 June 2010

Temporoparietal hypometabolism in frontotemporal lobar degeneration and associated imaging diagnostic errors.

scientific article

The Alzheimer's associated 5' region of the SORL1 gene cis regulates SORL1 transcripts expression

scientific article

The Haw River syndrome: dentatorubropallidoluysian atrophy (DRPLA) in an African-American family

scientific article (publication date: August 1994)

The cis-regulatory effect of an Alzheimer's disease-associated poly-T locus on expression of TOMM40 and apolipoprotein E genes

scientific article

The effect of SNCA 3' region on the levels of SNCA-112 splicing variant

scientific article

Toxicity of expanded polyglutamine-domain proteins in Escherichia coli.

scientific article

Twin pairs discordant for neuropathologically confirmed Lewy body dementia

scientific article published on May 2009

Using genetics to enable studies on the prevention of Alzheimer's disease

scientific article

Validation of consensus panel diagnosis in dementia

scientific article published on December 2010

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