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List of works by James B Leverenz

A Peruvian family with a novel PARK2 mutation: Clinical and pathological characteristics

scientific article published on 15 January 2015

A novel X-linked four-repeat tauopathy with Parkinsonism and spasticity

scientific article

A novel progranulin mutation associated with variable clinical presentation and tau, TDP43 and alpha-synuclein pathology

scientific article published on 17 April 2007

A randomized, double-blind phase I/IIa study of intranasal glutathione in Parkinson's disease

scientific article

ADAM10 expression and promoter haplotype in Alzheimer's disease

scientific article

APOE ε4 increases risk for dementia in pure synucleinopathies

scientific article published on February 2013

APOE, MAPT, and SNCA genes and cognitive performance in Parkinson disease

scientific article

Aberrant detergent-insoluble excitatory amino acid transporter 2 accumulates in Alzheimer disease.

scientific article

Aging-associated neuropathology in Werner syndrome

scientific article published in October 1998

Alpha- and beta-secretase activity as a function of age and beta-amyloid in Down syndrome and normal brain

scientific article

Alpha-synuclein in motor neuron disease: an immunohistologic study.

scientific article published on 29 November 2003

Alpha1-adrenoreceptor in human hippocampus: binding and receptor subtype mRNA expression

scientific article published in October 2005

Alternative processing of γ-secretase substrates in common forms of mild cognitive impairment and Alzheimer's disease: evidence for γ-secretase dysfunction

scientific article

Alzheimer's Disease and Maternal Age ⬇️

scientific article published on October 1, 1982

Alzheimer's disease phenotypes and genotypes associated with mutations in presenilin 2.

scientific article

Analysis of shared heritability in common disorders of the brain

scientific article published on 21 June 2018

Analysis of the LRRK2 G2019S mutation in Alzheimer Disease

scientific article

Apolipoprotein E highly correlates with AbetaPP- and tau-related markers in human cerebrospinal fluid.

scientific article

Application of targeted quantitative proteomics analysis in human cerebrospinal fluid using a liquid chromatography matrix-assisted laser desorption/ionization time-of-flight tandem mass spectrometer (LC MALDI TOF/TOF) platform

scientific article

Assessment of low-flow CSF drainage as a treatment for AD: results of a randomized pilot study

scientific article published in October 2002

Association between lifetime cigarette smoking and lewy body accumulation

scientific article

Association of cerebrospinal fluid Aβ42 with A2M gene in cognitively normal subjects

scientific article published on 04 September 2013

Association of cognitive domains with postural instability/gait disturbance in Parkinson's disease.

scientific article published on 14 April 2015

Associations between Markers of Glucose and Insulin Function and Cognitive Function in Healthy African American Elders

scientific article

Ataxin 1 and ataxin 3 in neuronal intranuclear inclusion disease

scientific article published on 01 August 1999

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Basic Mechanisms in Neurodegenerative Disease: Implications for Behavioral Pathogenesis and Treatment

scientific article published in October 1996

Biochemical, neuropathological, and neuroimaging characteristics of early-onset Alzheimer's disease due to a novel PSEN1 mutation

scientific article

Biomarker-driven phenotyping in Parkinson's disease: A translational missing link in disease-modifying clinical trials

scientific article published on 24 February 2017

BuChE-K and APOE epsilon4 allele frequencies in Lewy body dementias, and influence of genotype and hyperhomocysteinemia on cognitive decline.

scientific article

CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration.

scientific article

CSF Aβ(42) and tau in Parkinson's disease with cognitive impairment.

scientific article

Cerebellar Amyloid-β Plaques: How Frequent Are They, and Do They Influence 18F-Florbetaben SUV Ratios?

scientific article published on 30 June 2016

Cerebral perfusion and cortical thickness indicate cortical involvement in mild Parkinson's disease

scientific article

Cerebrospinal fluid Aβ42 levels and APP processing pathway genes in Parkinson's disease

scientific article published on 24 March 2015

Cerebrospinal fluid biomarkers and cognitive performance in non-demented patients with Parkinson's disease.

scientific article

Changes in adrenoreceptors in the prefrontal cortex of subjects with dementia: evidence of compensatory changes.

scientific article

Cheek cell-derived α-synuclein and DJ-1 do not differentiate Parkinson's disease from control

scientific article

Chronic cortisol exposure promotes the development of a GABAergic phenotype in the primate hippocampus.

scientific article published in November 2004

Chronic cortisol suppresses pituitary and hypothalamic peptide message expression in pigtailed macaques.

scientific article

Clinical and biochemical differences in patients having Parkinson disease with vs without GBA mutations.

scientific article

Clinical and molecular studies reveal a PSEN1 mutation (L153V) in a Peruvian family with early-onset Alzheimer's disease.

scientific article published on 02 February 2014

Clinical and neuropathological characteristics of hippocampal sclerosis: a community-based study

scientific article

Clinical aspects of hippocampal sclerosis

scientific article published in January 2008

Clinico-neuropathological correlation of Alzheimer's disease in a community-based case series

scientific article

Clinicopathologic correlations of soluble amyloid beta-protein precursor in cerebrospinal fluid in patients with Alzheimer disease and controls

scientific article published in December 1997

Clinicopathological concordance and discordance in three monozygotic twin pairs with familial Alzheimer's disease

scientific article

Co-morbidity of TDP-43 proteinopathy in Lewy body related diseases

scientific article

Cognitive impairment and dementia in patients with Parkinson disease.

scientific article published on January 2009

Cognitive impairment in older adults without dementia: clinical and pathologic outcomes in a community-based sample

scientific article published on 11 May 2009

Cognitive performance and neuropsychiatric symptoms in early, untreated Parkinson's disease.

scientific article published on 4 March 2015

Cognitive profile of LRRK2-related Parkinson's disease

scientific article

Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

scientific article

Compensatory changes in the noradrenergic nervous system in the locus ceruleus and hippocampus of postmortem subjects with Alzheimer's disease and dementia with Lewy bodies.

scientific article published in January 2006

Complement 3 and factor h in human cerebrospinal fluid in Parkinson's disease, Alzheimer's disease, and multiple-system atrophy

scientific article

Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature

scientific article published on May 2012

DJ-1 and αSYN in LRRK2 CSF do not correlate with striatal dopaminergic function

scientific article published on 21 October 2011

DOCK2 is a microglial specific regulator of central nervous system innate immunity found in normal and Alzheimer's disease brain.

scientific article published on 03 September 2009

Dementia with Lewy bodies

scientific article published on 01 May 2002

Detection of biomarkers with a multiplex quantitative proteomic platform in cerebrospinal fluid of patients with neurodegenerative disorders.

scientific article published in August 2006

Detergent-insoluble EAAC1/EAAT3 aberrantly accumulates in hippocampal neurons of Alzheimer's disease patients

scientific article published on 02 July 2008

Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium

scientific article

Diet intervention and cerebrospinal fluid biomarkers in amnestic mild cognitive impairment

scientific article published in June 2011

Diet-induced hypercholesterolemia enhances brain A beta accumulation in transgenic mice

scientific article

Differential response of the central noradrenergic nervous system to the loss of locus coeruleus neurons in Parkinson's disease and Alzheimer's disease

scientific article

Early amyloid deposition in the medial temporal lobe of young Down syndrome patients: a regional quantitative analysis

scientific article published in April 1998

Ecology of the aging human brain

scientific article published on August 2011

Effect of apolipoprotein E genotype and diet on apolipoprotein E lipidation and amyloid peptides: randomized clinical trial

scientific article

Effect of chronic high-dose exogenous cortisol on hippocampal neuronal number in aged nonhuman primates

scientific article published in March 1999

Effect of statins on Alzheimer's disease biomarkers in cerebrospinal fluid.

scientific article published in December 2006

Effect of vascular lesions on cognition in Alzheimer's disease: a community-based study

scientific article

Effects of chronic glucocorticoid administration on insulin-degrading enzyme and amyloid-beta peptide in the aged macaque.

scientific article

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study

scientific article

Empiric refinement of the pathologic assessment of Lewy-related pathology in the dementia patient

scientific article published on 29 January 2008

Evaluation of alpha-synuclein immunohistochemical methods used by invited experts

scientific article

Evaluation of mild cognitive impairment subtypes in Parkinson's disease.

scientific article

Familial dementia with lewy bodies: a clinical and neuropathological study of 2 families

scientific article published in October 2002

Familial prion disease with alzheimer disease‐like tau pathology and clinical phenotype ⬇️

scientific article published on March 17, 2011

Florbetaben PET imaging to detect amyloid beta plaques in Alzheimer's disease: phase 3 study

scientific article published on 27 March 2015

From model system to clinical medicine: pathophysiologic links of common proteinopathies.

scientific article

GBA Variants are associated with a distinct pattern of cognitive deficits in Parkinson's disease

scientific article

GBA mutations increase risk for Lewy body disease with and without Alzheimer disease pathology

scientific article

Genetic association between the APOE*4 allele and Lewy bodies in Alzheimer disease.

scientific article

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

Glucocerebrosidase gene mutations: a risk factor for Lewy body disorders

scientific article

Glucocorticoid induction of the glaucoma gene MYOC in human and monkey trabecular meshwork cells and tissues

scientific article

Glycoproteomics in neurodegenerative diseases

scientific article

Group comparison of spatiotemporal dynamics of intrinsic networks in Parkinson's disease

scientific article

Haptoglobin phenotype modifies serum iron levels and the effect of smoking on Parkinson disease risk

scientific article

High-intensity physical activity modulates diet effects on cerebrospinal amyloid-β levels in normal aging and mild cognitive impairment.

scientific article published on January 2012

Homocysteine and cognitive function in Parkinson's disease.

scientific article

Hyperphosphorylation of RNA polymerase II and reduced neuronal RNA levels precede neurofibrillary tangles in Alzheimer disease

scientific article

Immunoglobulins, cognitive status and duration of illness in alzheimer's disease

scientific article published in January 1980

Impact of Alzheimer's Disease, Lewy Body and Vascular Co-Pathologies on Clinical Transition to Dementia in a National Autopsy Cohort

scientific article

Impact of Training Method on the Robustness of the Visual Assessment of 18F-Florbetaben PET Scans: Results from a Phase-3 Study

scientific article published on 28 January 2016

Increased alpha 2-adrenergic receptor binding in locus coeruleus projection areas in dementia with Lewy bodies.

scientific article published in July 2001

Infection of Macaca nemestrina brain with human immunodeficiency virus type 1 ⬇️

scientific article published on October 1, 1995

Influence of lifestyle modifications on age-related free radical injury to brain

scientific article

Interrater reliability and accuracy in identifying ischemic strokes using computed tomography scans in people with dementia

scientific article published in October 2005

Lewy body pathology in familial Alzheimer disease: evidence for disease- and mutation-specific pathologic phenotype

scientific article published in March 2006

Lewy body pathology in late-onset familial Alzheimer's disease: a clinicopathological case series.

scientific article published in August 2006

Little evidence of reduced survival to adulthood of apoE epsilon4 homozygotes in Down's syndrome.

scientific article published in November 1997

Longitudinal change in regional brain volumes with exposure to repetitive head impacts

scientific article published on 23 December 2019

Lower plasma apolipoprotein A1 levels are found in Parkinson's disease and associate with apolipoprotein A1 genotype

scientific article

MSUT2 is a determinant of susceptibility to tau neurotoxicity

scientific article

Memory, mood, and vitamin D in persons with Parkinson's disease

scientific article published on January 2013

MicroRNA in Alzheimer's disease: an exploratory study in brain, cerebrospinal fluid and plasma

scientific article published on 03 July 2013

Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy

scientific article

Neuropathologic substrates of Parkinson disease dementia

scientific article

Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria

scientific article published on December 2009

Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis ⬇️

scientific article published on 19 October 2020

PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease

scientific article

Parkinson's disease in patients with Alzheimer's disease

scientific article published in July 1986

Pathologic correlates of dementia in individuals with Lewy body disease

scientific article

Pathological changes in frontal cortex from biopsy to autopsy in Alzheimer's disease

scientific article published in November 1993

Pathological correlates of dementia in a longitudinal, population-based sample of aging

scientific article published in October 2007

Phosphorylated α-synuclein in Parkinson's disease: correlation depends on disease severity

scientific article

Predicting lewy body pathology in a community-based sample with clinical diagnosis of Alzheimer's disease

scientific article published in December 2006

Preservation of noradrenergic neurons in the locus ceruleus that coexpress galanin mRNA in Alzheimer's disease.

scientific article published on November 1999

Protein changes during aging and the effects of long-term cortisol treatment in macaque monkey lens

scientific article published on 01 April 1997

Proteomic identification of novel proteins in cortical lewy bodies

scientific article published in April 2007

R47H Variant of TREM2 Associated With Alzheimer Disease in a Large Late-Onset Family: Clinical, Genetic, and Neuropathological Study

scientific article

Rarity of the Alzheimer disease-protective APP A673T variant in the United States

scientific article

Rate of progression differs in frontotemporal dementia and Alzheimer disease.

scientific article

Regulatory region genetic variation is associated with FYN expression in Alzheimer's disease.

scientific article published on 15 November 2016

Research criteria for the diagnosis of prodromal dementia with Lewy bodies

scientific article published on 02 April 2020

Response to the letter "Haptoglobin phenotype and Parkinson disease risk" by Delanghe et al.

scientific article published on January 2016

Retinal Nerve Fiber Layer Thinning in Alzheimer's Disease: A Case-Control Study in Comparison to Normal Aging, Parkinson's Disease, and Non-Alzheimer's Dementia

scientific article published on 16 February 2016

Rosiglitazone attenuates learning and memory deficits in Tg2576 Alzheimer mice

scientific article published on 3 March 2006

SNCA variant associated with Parkinson disease and plasma alpha-synuclein level

scientific article

SNPs associated with cerebrospinal fluid phospho-tau levels influence rate of decline in Alzheimer's disease

scientific article

Salivary α-synuclein and DJ-1: potential biomarkers for Parkinson's disease.

scientific article published on 24 February 2011

Selective dendritic degeneration of medium spiny neurons in dementia with Lewy bodies.

scientific article published in May 2006

Sex differences in progression to mild cognitive impairment and dementia in Parkinson's disease

scientific article published on 9 February 2018

Significance and confounders of peripheral DJ-1 and alpha-synuclein in Parkinson's disease.

scientific article

Sleep and Neurodegeneration: A Critical Appraisal.

scientific article published on 10 January 2017

Specific downregulation of presenilin 2 gene expression is prominent during early stages of sporadic late-onset Alzheimer's disease

scientific article published in May 2000

TREM2 and Neurodegenerative Disease

scientific article published on 01 October 2013

TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models.

scientific article

Tau isoform regulation is region- and cell-specific in mouse brain.

scientific article

Tau phosphorylation pathway genes and cerebrospinal fluid tau levels in Alzheimer's disease

scientific article published on 27 August 2012

Temporoparietal hypometabolism in frontotemporal lobar degeneration and associated imaging diagnostic errors.

scientific article

The RAB39B p.G192R mutation causes X-linked dominant Parkinson's disease

scientific article

The biomarker and therapeutic potential of miRNA in Alzheimer's disease.

scientific article

The effect of apolipoprotein E genotype on expression of an autosomal dominant schizophreniform disorder with progressive dementia and neurofibrillary tangles

scientific article published in January 1997

The expanding role of genetics in the lewy body diseases: the glucocerebrosidase gene.

scientific article published on May 2009

The neurobiological basis of cognitive impairment in Parkinson's disease

scientific article

The tau tubulin kinases TTBK1/2 promote accumulation of pathological TDP-43

scientific article (publication date: December 2014)

Tyrosine hydroxylase and norepinephrine transporter mRNA expression in the locus coeruleus in Alzheimer's disease

scientific article published in December 2000

Validation of consensus panel diagnosis in dementia

scientific article published on December 2010

Visual hallucinations in dementia: a prospective community-based study with autopsy

scientific article published on April 2009

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