Search filters

List of works by Jean-Marc Daran

A CRISPR/Cas9-based exploration into the elusive mechanism for lactate export in Saccharomyces cerevisiae

scientific article published on 14 November 2017

A Minimal Set of Glycolytic Genes Reveals Strong Redundancies in Saccharomyces cerevisiae Central Metabolism

scientific article published on 12 June 2015

A new laboratory evolution approach to select for constitutive acetic acid tolerance in Saccharomyces cerevisiae and identification of causal mutations.

scientific article published on 12 August 2016

A new physiological role for Pdr12p in Saccharomyces cerevisiae: export of aromatic and branched-chain organic acids produced in amino acid catabolism.

scientific article published on September 2006

A protocol for introduction of multiple genetic modifications in Saccharomyces cerevisiae using CRISPR/Cas9

scientific article published in 2018

A toolkit for rapid CRISPR-SpCas9 assisted construction of hexose-transport-deficient Saccharomyces cerevisiae strains

article

A versatile, efficient strategy for assembly of multi-fragment expression vectors in Saccharomyces cerevisiae using 60 bp synthetic recombination sequences.

scientific article

Acclimation of Saccharomyces cerevisiae to low temperature: a chemostat-based transcriptome analysis

scientific article published on 10 October 2007

Allele-specific genome editing using CRISPR-Cas9 is associated with loss of heterozygosity in diploid yeast

scientific article published on 01 February 2019

Alleviation of feedback inhibition in Saccharomyces cerevisiae aromatic amino acid biosynthesis: quantification of metabolic impact

scientific article published on 20 February 2008

Alternative reactions at the interface of glycolysis and citric acid cycle in Saccharomyces cerevisiae

scientific article published on 18 February 2016

An alternative, arginase-independent pathway for arginine metabolism in Kluyveromyces lactis involves guanidinobutyrase as a key enzyme.

scientific article published on 23 June 2014

An atypical PMR2 locus is responsible for hypersensitivity to sodium and lithium cations in the laboratory strain Saccharomyces cerevisiae CEN.PK113-7D

scientific article published on 14 May 2009

An internal deletion in MTH1 enables growth on glucose of pyruvate-decarboxylase negative, non-fermentative Saccharomyces cerevisiae.

scientific article published on 15 September 2012

CRISPR-Cas9 mediated gene deletions in lager yeast Saccharomyces pastorianus

scientific article published on 5 December 2017

CRISPR/Cas9: a molecular Swiss army knife for simultaneous introduction of multiple genetic modifications in Saccharomyces cerevisiae

scientific article published on 04 March 2015

Carbon dioxide fixation by Calvin-Cycle enzymes improves ethanol yield in yeast

scientific article published on 29 August 2013

Chemostat-based micro-array analysis in baker's yeast.

scientific article published on January 2009

Chromosomal Copy Number Variation in Saccharomyces pastorianus Is Evidence for Extensive Genome Dynamics in Industrial Lager Brewing Strains.

scientific article

Combinatorial effects of environmental parameters on transcriptional regulation in Saccharomyces cerevisiae: a quantitative analysis of a compendium of chemostat-based transcriptome data.

scientific article

Combined engineering of disaccharide transport and phosphorolysis for enhanced ATP yield from sucrose fermentation in Saccharomyces cerevisiae.

scientific article

Comparative assessment of native and heterologous 2-oxo acid decarboxylases for application in isobutanol production by Saccharomyces cerevisiae.

scientific article published on December 2015

Comparative genotyping of the Saccharomyces cerevisiae laboratory strains S288C and CEN.PK113-7D using oligonucleotide microarrays.

scientific article published in December 2003

Connecting central carbon and aromatic amino acid metabolisms to improve de novo 2-phenylethanol production in Saccharomyces cerevisiae

scientific article published on 28 September 2019

Construction of an hdfA Penicillium chrysogenum strain impaired in non-homologous end-joining and analysis of its potential for functional analysis studies

scientific article published on 6 March 2009

Contribution of the Saccharomyces cerevisiae transcriptional regulator Leu3p to physiology and gene expression in nitrogen- and carbon-limited chemostat cultures.

scientific article

Control of the Glycolytic Flux inSaccharomyces cerevisiaeGrown at Low Temperature

scientific article published in Journal of Biological Chemistry

Correlation between transcript profiles and fitness of deletion mutants in anaerobic chemostat cultures of Saccharomyces cerevisiae.

scientific article published on March 2007

De novo detection of copy number variation by co-assembly.

scientific article published on 9 October 2012

De novo production of the flavonoid naringenin in engineered Saccharomyces cerevisiae

scientific article published on 8 December 2012

De novo sequencing, assembly and analysis of the genome of the laboratory strain Saccharomyces cerevisiae CEN.PK113-7D, a model for modern industrial biotechnology

scientific article published on 26 March 2012

Degeneration of penicillin production in ethanol-limited chemostat cultivations of Penicillium chrysogenum: A systems biology approach

scientific article published on August 19, 2011

Deletion of theSaccharomyces cerevisiae ARO8gene, encoding an aromatic amino acid transaminase, enhances phenylethanol production from glucose

article

Determination of the Cytosolic NADPH/NADP Ratio in Saccharomyces cerevisiae using Shikimate Dehydrogenase as Sensor Reaction.

scientific article published on 5 August 2015

Discovery and Synthetic Applications of a NAD(P)H-Dependent Reductive Aminase from

scientific article published on 3 January 2025

Efficient simultaneous excision of multiple selectable marker cassettes using I-SceI-induced double-strand DNA breaks in Saccharomyces cerevisiae

scientific article published on 27 June 2014

Elimination of sucrose transport and hydrolysis in Saccharomyces cerevisiae: a platform strain for engineering sucrose metabolism.

scientific article published on 12 January 2017

Engineering acetyl coenzyme A supply: functional expression of a bacterial pyruvate dehydrogenase complex in the cytosol of Saccharomyces cerevisiae.

scientific article

Engineering and analysis of a Saccharomyces cerevisiae strain that uses formaldehyde as an auxiliary substrate

scientific article (publication date: May 2008)

Engineering de novo anthocyanin production in Saccharomyces cerevisiae.

scientific article published on 3 July 2018

Engineering of Penicillium chrysogenum for fermentative production of a novel carbamoylated cephem antibiotic precursor.

scientific article published in March 2009

Engineering topology and kinetics of sucrose metabolism in Saccharomyces cerevisiae for improved ethanol yield

scientific article published on 22 September 2011

Evolutionary Engineering in Chemostat Cultures for Improved Maltotriose Fermentation Kinetics in Saccharomyces pastorianus Lager Brewing Yeast.

scientific article published on 8 September 2017

Excessive by-product formation: A key contributor to low isobutanol yields of engineered Saccharomyces cerevisiae strains

scientific article published on 20 January 2016

Exploiting combinatorial cultivation conditions to infer transcriptional regulation

scientific article

Exploring and dissecting genome-wide gene expression responses of Penicillium chrysogenum to phenylacetic acid consumption and penicillinG production

scientific article

Exploring the abundance of oleate hydratases in the genus Rhodococcus-discovery of novel enzymes with complementary substrate scope

scientific article published on 01 May 2020

Fermentation of glucose-xylose-arabinose mixtures by a synthetic consortium of single-sugar-fermenting Saccharomyces cerevisiae strains

scientific article published on 01 December 2018

FnCpf1: a novel and efficient genome editing tool for Saccharomyces cerevisiae

scientific article published on 2 November 2017

Functional analysis and transcriptional regulation of two orthologs of ARO10, encoding broad-substrate-specificity 2-oxo-acid decarboxylases, in the brewing yeast Saccharomyces pastorianus CBS1483.

scientific article

Functional characterization of a Penicillium chrysogenum mutanase gene induced upon co-cultivation with Bacillus subtilis

scientific article

Functional characterization of the oxaloacetase encoding gene and elimination of oxalate formation in the β-lactam producer Penicillium chrysogenum.

scientific article published on 29 April 2011

Functional expression of a heterologous nickel-dependent, ATP-independent urease in Saccharomyces cerevisiae

scientific article published on 30 May 2015

Genetic and Biochemical Characterization of the UGP1 Gene Encoding the UDP‐Glucose Pyrophosphorylase from Saccharomyces cerevisiae

scientific article published on October 15, 1995

Genome duplication and mutations in ACE2 cause multicellular, fast-sedimenting phenotypes in evolved Saccharomyces cerevisiae.

scientific article published on 21 October 2013

Genome editing in Kluyveromyces and Ogataea yeasts using a broad-host-range Cas9/gRNA co-expression plasmid

scientific article published on 9 February 2018

Genome sequencing and analysis of the filamentous fungus Penicillium chrysogenum

scientific article

Genome-wide analytical approaches for reverse metabolic engineering of industrially relevant phenotypes in yeast.

scientific article published on 10 January 2012

Heterologous carotenoid production in Saccharomyces cerevisiae induces the pleiotropic drug resistance stress response

scientific article published on 01 December 2010

Himalayan Saccharomyces eubayanus Genome Sequences Reveal Genetic Markers Explaining Heterotic Maltotriose Consumption by Saccharomyces pastorianus Hybrids

scientific article published on 30 October 2019

Identification of Oxygen-Independent Pathways for Pyridine Nucleotide and Coenzyme A Synthesis in Anaerobic Fungi by Expression of Candidate Genes in Yeast

scientific article published on 22 June 2021

Identity of the growth-limiting nutrient strongly affects storage carbohydrate accumulation in anaerobic chemostat cultures of Saccharomyces cerevisiae

scientific article published on 4 September 2009

Impact of velvet complex on transcriptome and penicillin G production in glucose-limited chemostat cultures of a β-lactam high-producing Penicillium chrysogenum strain.

scientific article published on 22 March 2012

In vivo analysis of Saccharomyces cerevisiae plasma membrane ATPase Pma1p isoforms with increased in vitro H+/ATP stoichiometry.

scientific article published on 10 April 2012

In vivo recombination of Saccharomyces eubayanus maltose-transporter genes yields a chimeric transporter that enables maltotriose fermentation

article

Increasing free-energy (ATP) conservation in maltose-grown Saccharomyces cerevisiae by expression of a heterologous maltose phosphorylase

scientific article published on 17 June 2011

Industrial Relevance of Chromosomal Copy Number Variation in Saccharomyces Yeasts.

scientific article published on 24 March 2017

Integrating genome assemblies with MAIA.

scientific article published on September 2010

Involvement of Snf7p and Rim101p in the transcriptional regulation of TIR1 and other anaerobically upregulated genes in Saccharomyces cerevisiae.

scientific article

Involvement of vacuolar sequestration and active transport in tolerance of Saccharomyces cerevisiae to hop iso-alpha-acids.

scientific article published on 13 November 2009

Laboratory Evolution of a Biotin-Requiring Saccharomyces cerevisiae Strain for Full Biotin Prototrophy and Identification of Causal Mutations.

scientific article published on 9 June 2017

Laboratory Evolution of a × Hybrid Under Simulated Lager-Brewing Conditions

scientific article published on 29 March 2019

Laboratory evolution of a glucose-phosphorylation-deficient, arabinose-fermenting S. cerevisiae strain reveals mutations in GAL2 that enable glucose-insensitive l-arabinose uptake

scientific article published on 01 September 2018

Laboratory evolution of new lactate transporter genes in a jen1Δ mutant of Saccharomyces cerevisiae and their identification as ADY2 alleles by whole-genome resequencing and transcriptome analysis

scientific article published on 18 January 2012

Lager-brewing yeasts in the era of modern genetics

scientific article published on 01 November 2019

Long-term adaptation of Saccharomyces cerevisiae to the burden of recombinant insulin production

scientific article published on 14 May 2013

Membrane potential independent transport of NH3 in the absence of ammonium permeases in Saccharomyces cerevisiae.

scientific article

Metabolic engineering of β-oxidation in Penicillium chrysogenum for improved semi-synthetic cephalosporin biosynthesis

scientific article published on 22 February 2012

Multiplex genome editing of microorganisms using CRISPR-Cas

scientific article published on 01 April 2019

Mutations in PMR1 stimulate xylose isomerase activity and anaerobic growth on xylose of engineered Saccharomyces cerevisiae by influencing manganese homeostasis.

scientific article published on 12 April 2017

Nanopore sequencing enables near-complete de novo assembly of Saccharomyces cerevisiae reference strain CEN.PK113-7D.

scientific article

One-step assembly and targeted integration of multigene constructs assisted by the I-SceI meganuclease in Saccharomyces cerevisiae

scientific article

Pathway swapping: Toward modular engineering of essential cellular processes.

scientific article

Phenotype-Independent Isolation of Interspecies Hybrids by Dual-Dye Fluorescent Staining and Fluorescence-Activated Cell Sorting

scientific article published on 26 April 2019

Physiological and morphological effects of genetic alterations leading to a reduced synthesis of UDP-glucose in Saccharomyces cerevisiae

scientific article published on August 1, 1997

Physiological and transcriptional responses of Saccharomyces cerevisiae to zinc limitation in chemostat cultures

scientific article published on 12 October 2007

Physiological characterization of the ARO10-dependent, broad-substrate-specificity 2-oxo acid decarboxylase activity of Saccharomyces cerevisiae.

scientific article

Polycistronic expression of a β-carotene biosynthetic pathway in Saccharomyces cerevisiae coupled to β-ionone production

scientific article published on 28 January 2014

Predicting metabolic fluxes using gene expression differences as constraints

scientific article published in January 2011

Replacement of the Saccharomyces cerevisiae acetyl-CoA synthetases by alternative pathways for cytosolic acetyl-CoA synthesis

scientific article published on 19 November 2013

Replacement of the initial steps of ethanol metabolism in Saccharomyces cerevisiae by ATP-independent acetylating acetaldehyde dehydrogenase.

scientific article published on 26 January 2016

Requirements for Carnitine Shuttle-Mediated Translocation of Mitochondrial Acetyl Moieties to the Yeast Cytosol

scientific article published on 3 May 2016

Resolving phenylalanine metabolism sheds light on natural synthesis of penicillin G in Penicillium chrysogenum.

scientific article published on 9 December 2011

Role of transcriptional regulation in controlling fluxes in central carbon metabolism of Saccharomyces cerevisiae. A chemostat culture study.

scientific article published on 20 November 2003

S. cerevisiae × S. eubayanus interspecific hybrid, the best of both worlds and beyond

scientific article published on 4 March 2015

Selection of Pof-Saccharomyces eubayanus Variants for the Construction of S. cerevisiae × S. eubayanus Hybrids With Reduced 4-Vinyl Guaiacol Formation

scientific article published on 27 July 2018

Stress-induced expression is enriched for evolutionarily young genes in diverse budding yeasts

scientific article published on 01 May 2020

Structural, Physiological and Regulatory Analysis of Maltose Transporter Genes in CBS 12357

article

Substrate specificity of thiamine pyrophosphate-dependent 2-oxo-acid decarboxylases in Saccharomyces cerevisiae.

scientific article

The Ehrlich pathway for fusel alcohol production: a century of research on Saccharomyces cerevisiae metabolism

scientific article

The Penicillium chrysogenum aclA gene encodes a broad-substrate-specificity acyl-coenzyme A ligase involved in activation of adipic acid, a side-chain precursor for cephem antibiotics

scientific article published on January 2010

The Penicillium chrysogenum transporter PcAraT enables high-affinity, glucose-insensitive l-arabinose transport in Saccharomyces cerevisiae.

scientific article

The fluxes through glycolytic enzymes in Saccharomyces cerevisiae are predominantly regulated at posttranscriptional levels

scholarly article

The genome sequence of the popular hexose-transport-deficient Saccharomyces cerevisiae strain EBY.VW4000 reveals LoxP/Cre-induced translocations and gene loss

scientific article published on March 2015

Toward Developing a Yeast Cell Factory for the Production of Prenylated Flavonoids

scientific article published on 02 May 2019

Transcriptional responses ofSaccharomyces cerevisiaeto preferred and nonpreferred nitrogen sources in glucose-limited chemostat cultures

article

Two-dimensional transcriptome analysis in chemostat cultures. Combinatorial effects of oxygen availability and macronutrient limitation in Saccharomyces cerevisiae.

scientific article published on 20 October 2004

Under pressure: evolutionary engineering of yeast strains for improved performance in fuels and chemicals production

scientific article published on 17 November 2017

Vitamin requirements and biosynthesis in Saccharomyces cerevisiae

scientific article published on 06 February 2020

When transcriptome meets metabolome: fast cellular responses of yeast to sudden relief of glucose limitation.

scientific article published on 12 September 2006

amdSYM, a new dominant recyclable marker cassette for Saccharomyces cerevisiae

scientific article published on 17 December 2012