List of works - Martin J Stoermer

Activity of recombinant dengue 2 virus NS3 protease in the presence of a truncated NS2B co-factor, small peptide substrates, and inhibitors.

scientific article published on October 2001

Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria

scientific article

Structure of West Nile virus NS3 protease: ligand stabilization of the catalytic conformation

scientific article

Enzymatic characterization and homology model of a catalytically active recombinant West Nile virus NS3 protease

scientific article published on 18 August 2004

Insights to substrate binding and processing by West Nile Virus NS3 protease through combined modeling, protease mutagenesis, and kinetic studies

scientific article published on 19 October 2006

Potent cyclic antagonists of the complement C5a receptor on human polymorphonuclear leukocytes. Relationships between structures and activity.

scientific article published in April 2004

In silico screening of small molecule libraries using the dengue virus envelope E protein has identified compounds with antiviral activity against multiple flaviviruses

scientific article

Orally Absorbed Cyclic Peptides

scientific article published on 25 May 2017

Potent cationic inhibitors of West Nile virus NS2B/NS3 protease with serum stability, cell permeability and antiviral activity

scientific article published on 26 August 2008

Site-directed mutagenesis and kinetic studies of the West Nile Virus NS3 protease identify key enzyme-substrate interactions.

scientific article published on 19 October 2004

Mutagenesis of the West Nile virus NS2B cofactor domain reveals two regions essential for protease activity

scientific article

Flavones are inhibitors of HIV-1 proteinase

scientific article (publication date: 30 October 1992)

An interaction between the methyltransferase and RNA dependent RNA polymerase domains of the West Nile virus NS5 protein

scientific article published on 5 June 2013

Receptor residence time trumps drug-likeness and oral bioavailability in determining efficacy of complement C5a antagonists.

scientific article

Cyclic Penta- and Hexaleucine Peptides without N-Methylation Are Orally Absorbed

scientific article

Generation and characterization of proteolytically active and highly stable truncated and full-length recombinant West Nile virus NS3.

scientific article published on 7 November 2006

Simultaneous uncoupled expression and purification of the Dengue virus NS3 protease and NS2B co-factor domain.

scientific article published on 29 November 2015

Downsizing a human inflammatory protein to a small molecule with equal potency and functionality.

scientific article

Virtual Screening of Peptide and Peptidomimetic Fragments Targeted to Inhibit Bacterial Dithiol Oxidase DsbA

scientific article

Structural mimicry of two cytochrome b(562) interhelical loops using macrocycles constrained by oxazoles and thiazoles

scientific article

Three Homology Models of PAR2 Derived from Different Templates: Application to Antagonist Discovery.

scientific article published on 22 May 2015

Cycloadditions of isobenzofuran to a constrained template bearing neighboring dienophiles

scientific article published in May 2003

Identification and characterization of bi-thiazole-2,2'-diamines as kinase inhibitory scaffolds.

scientific article published on 11 February 2013

Potent heterocyclic ligands for human complement c3a receptor

scientific article published on 8 October 2014

Regioselective Synthesis of Antiparallel Loops on a Macrocyclic Scaffold Constrained by Oxazoles and Thiazoles

scientific article published on 01 October 2002

Synthesis and cannabinoid activity of 1-substituted-indole-3-oxadiazole derivatives: novel agonists for the CB1 receptor.

scientific article

Structures of peptide agonists for human protease activated receptor 2.

scientific article

Identification of crotonyl glycine in urine of sheep after 48 h road transport

scientific article published on 25 April 2012

List of works by Martin J Stoermer

Activity of recombinant dengue 2 virus NS3 protease in the presence of a truncated NS2B co-factor, small peptide substrates, and inhibitors.

Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria

Structure of West Nile virus NS3 protease: ligand stabilization of the catalytic conformation

Enzymatic characterization and homology model of a catalytically active recombinant West Nile virus NS3 protease

Insights to substrate binding and processing by West Nile Virus NS3 protease through combined modeling, protease mutagenesis, and kinetic studies

Potent cyclic antagonists of the complement C5a receptor on human polymorphonuclear leukocytes. Relationships between structures and activity.

In silico screening of small molecule libraries using the dengue virus envelope E protein has identified compounds with antiviral activity against multiple flaviviruses

Orally Absorbed Cyclic Peptides

Potent cationic inhibitors of West Nile virus NS2B/NS3 protease with serum stability, cell permeability and antiviral activity

Site-directed mutagenesis and kinetic studies of the West Nile Virus NS3 protease identify key enzyme-substrate interactions.

Mutagenesis of the West Nile virus NS2B cofactor domain reveals two regions essential for protease activity

Flavones are inhibitors of HIV-1 proteinase

An interaction between the methyltransferase and RNA dependent RNA polymerase domains of the West Nile virus NS5 protein

Receptor residence time trumps drug-likeness and oral bioavailability in determining efficacy of complement C5a antagonists.

Cyclic Penta- and Hexaleucine Peptides without N-Methylation Are Orally Absorbed

Generation and characterization of proteolytically active and highly stable truncated and full-length recombinant West Nile virus NS3.

Simultaneous uncoupled expression and purification of the Dengue virus NS3 protease and NS2B co-factor domain.

Downsizing a human inflammatory protein to a small molecule with equal potency and functionality.

Virtual Screening of Peptide and Peptidomimetic Fragments Targeted to Inhibit Bacterial Dithiol Oxidase DsbA

Structural mimicry of two cytochrome b(562) interhelical loops using macrocycles constrained by oxazoles and thiazoles

Three Homology Models of PAR2 Derived from Different Templates: Application to Antagonist Discovery.

Cycloadditions of isobenzofuran to a constrained template bearing neighboring dienophiles

Identification and characterization of bi-thiazole-2,2'-diamines as kinase inhibitory scaffolds.

Potent heterocyclic ligands for human complement c3a receptor

Regioselective Synthesis of Antiparallel Loops on a Macrocyclic Scaffold Constrained by Oxazoles and Thiazoles

Synthesis and cannabinoid activity of 1-substituted-indole-3-oxadiazole derivatives: novel agonists for the CB1 receptor.

Structures of peptide agonists for human protease activated receptor 2.

Identification of crotonyl glycine in urine of sheep after 48 h road transport