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List of works by Guruprasad P. Aithal

1 and 5 year survival estimates for people with cirrhosis of the liver in England, 1998-2009: a large population study

scientific article published on 12 October 2013

A Missense Variant in PTPN22 is a Risk Factor for Drug-induced Liver Injury

scientific article published on 18 January 2019

A Randomized, Placebo-Controlled Trial of Cenicriviroc for Treatment of Nonalcoholic Steatohepatitis with Fibrosis.

scientific article published on 17 August 2017

A low calorie morning meal prevents the decline of hepatic glycogen stores: a pilot in vivo13C magnetic resonance study

scientific article published on 01 September 2014

A not-so-simple collapse

scientific article published on 01 September 2003

A role for the pregnane X receptor in flucloxacillin-induced liver injury.

scientific article published in May 2010

A study of T₁ relaxation time as a measure of liver fibrosis and the influence of confounding histological factors.

scientific article published on 24 April 2015

ADAPT: An Algorithm Incorporating PRO-C3 Accurately Identifies Patients With NAFLD and Advanced Fibrosis

scientific article published on 01 March 2019

Abnormal liver tests in people aged 75 and above: prevalence and association with mortality

scientific article published on 01 June 2011

Accuracy of EUS for detection of intraductal papillary mucinous tumor of the pancreas

scientific article published on 01 November 2002

Accurate non-invasive diagnosis and staging of non-alcoholic fatty liver disease using the urinary steroid metabolome

scientific article published on 16 April 2020

Acute Hyperenergetic, High-Fat Feeding Increases Circulating FGF21, LECT2, and Fetuin-A in Healthy Men

scientific article published on 09 January 2020

Adjuvant treatment for colorectal cancer. Reducing avoidable delays in establishing the diagnosis is also important

scientific article published in June 1996

All‐cause mortality in people with cirrhosis compared with the general population: a population‐based cohort study ⬇️

scientific article published on April 6, 2011

Analysis of genotyping for predicting liver injury marker, procollagen III in persons at risk of non-alcoholic fatty liver disease

scientific article published on 25 March 2018

Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study

scientific article published on 30 December 2016

Association of non-alcoholic steatohepatitis without significant fibrosis with hepatocellular carcinoma

scientific article published on 01 October 2004

Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications

scientific article published on 01 February 1999

Association of single nucleotide polymorphisms in the interleukin-4 gene and interleukin-4 receptor gene with Crohn's disease in a British population

scientific article published on 01 February 2001

Autoimmune cholestatic liver disease in people with coeliac disease: a population-based study of their association.

scientific article

Biomarkers in liver disease: emerging methods and potential applications

scientific article

Brunner's gland hyperplasia at the ampulla of Vater.

scientific article

CYP2C9 polymorphism and warfarin dose requirements

scientific article published on April 2002

Care standards for non-alcoholic fatty liver disease in the United Kingdom 2016: a cross-sectional survey

scientific article published on 28 April 2017

Case definition and phenotype standardization in drug-induced liver injury.

scientific article published on 04 May 2011

Causality assessment for suspected DILI during clinical phases of drug development

scientific article

Cenicriviroc Treatment for Adults with Nonalcoholic Steatohepatitis and Fibrosis: Final Analysis of the Phase 2b CENTAUR Study

scientific article published on 13 January 2020

Chest pain in achalasia is an age-dependent phenomenon

scientific article published on 01 November 1999

Clinical and microbiological features of infection in alcoholic hepatitis: an international cohort study

scientific article published on 7 April 2017

Clinical diagnostic scale: a useful tool in the evaluation of suspected hepatotoxic adverse drug reactions

scientific article published in December 2000

Cohort profile: the Trivandrum non-alcoholic fatty liver disease (NAFLD) cohort

scientific article published on 05 May 2019

Concurrent mucinous cystadenoma of the liver and bile duct: a rare cause of jaundice

scientific article

Dangerous liaisons: drug, host and the environment

scientific article published on 09 April 2007

Defining 'acute on chronic liver failure': an identity crisis!

scientific article published on 01 September 2010

Development and evaluation of a nurse-led transient elastography service for the staging of hepatic fibrosis in patients with suspected chronic liver disease

scientific article published on 09 March 2012

Diagnosis, presentation and initial severity of Autoimmune Hepatitis (AIH) in patients attending 28 hospitals in the UK.

scientific article published on 17 February 2018

Diagnostic accuracy of non-invasive tests for advanced fibrosis in patients with NAFLD: an individual patient data meta-analysis

scientific article published in 2021

Diclofenac-induced liver injury: a paradigm of idiosyncratic drug toxicity

scientific article published in November 2004

Diffuse nesidioblastosis causing hyperinsulinemic hypoglycemia: the importance of pancreatic sampling on EUS

scientific article published on 11 June 2008

Direct targeting of risk factors significantly increases the detection of liver cirrhosis in primary care: a cross-sectional diagnostic study utilising transient elastography

scientific article published on 3 May 2015

Drug Development for Nonalcoholic Fatty Liver Disease: Landscape and Challenges

scientific article published on 13 March 2019

Drug-Induced Liver Injury due to Flucloxacillin: Relevance of Multiple Human Leukocyte Antigen Alleles

scientific article published on 19 March 2019

Drug-induced liver injury: recent advances in diagnosis and risk assessment

scientific article

Dynamics of 5-carboxylcytosine during hepatic differentiation: Potential general role for active demethylation by DNA repair in lineage specification.

scientific article

Dyspnoea in a patient with cirrhosis

scientific article published on 01 January 2009

EUS-guided Trucut mural biopsies in the investigation of unexplained thickening of the esophagogastric wall

scientific article published on 01 October 2005

EUS-guided pancreatic cyst brushing: a comparative study in a tertiary referral centre

scientific article published on 05 March 2010

EUS-guided tissue sampling: comparison of "dual sampling" (Trucut biopsy plus FNA) with "sequential sampling" (Trucut biopsy and then FNA as required)

scientific article published on 10 July 2007

Economic evaluation of a community-based diagnostic pathway to stratify adults for non-alcoholic fatty liver disease: a Markov model informed by a feasibility study

scientific article

Economic modelling of early transjugular intrahepatic portosystemic shunt insertion for acute variceal haemorrhage

scientific article published in February 2013

Editorial: treating hepatorenal syndrome-a window and the views

scientific article published on 01 September 2020

Effect of exercise intensity on circulating hepatokine concentrations in healthy men

scientific article published on 27 August 2019

Effectiveness of a nurse-led alcohol liaison service in a secondary care medical unit.

scientific article published on October 2010

Effects of Environmental Factors on Severity and Mortality of COVID-19

scientific article

Effects of environmental factors on severity and mortality of COVID-19

scientific article

Effects of short-term energy restriction on liver lipid content and inflammatory status in severely obese adults: Results of a randomized controlled trial using 2 dietary approaches

scientific article

Effects of sprint interval training on ectopic lipids and tissue-specific insulin sensitivity in men with non-alcoholic fatty liver disease

scientific article published on 6 February 2018

Efficacy of recombinant human interleukin-10 in prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis in subjects with increased risk

scientific article published in April 2009

Efficacy, safety, and predictive factors for a positive yield of EUS-guided Trucut biopsy: a large tertiary referral center experience

scientific article

Elevated serum alanine transaminase in patients with type 1 or type 2 diabetes mellitus.

scientific article published on December 2006

Elevation of alanine transaminase and markers of liver fibrosis after a mixed meal challenge in individuals with type 2 diabetes

scientific article published on 17 May 2012

End-stage methotrexate-related liver disease is rare and associated with features of the metabolic syndrome

scientific article

Endoscopic-ultrasound-guided mural trucut biopsy in the investigation of unexplained thickening of esophagogastric wall

scientific article published in April 2009

Evaluation of laboratory tests for cirrhosis and for alcohol use, in the context of alcoholic cirrhosis

scientific article

Fast-food hyper-alimentation and exercise restriction in healthy subjects.

scientific article published in March 2009

Fracture Risk in People With Primary Biliary Cirrhosis: A Population-Based Cohort Study

scientific article published on 08 September 2006

Genetic basis of drug-induced liver injury: present and future

scientific article published on 31 May 2014

Genetic regulation of warfarin metabolism and response

scientific article

Genetic susceptibility to diclofenac-induced hepatotoxicity: contribution of UGT2B7, CYP2C8, and ABCC2 genotypes

scientific article published on 17 November 2006

Genetic variation in HSD17B13 reduces the risk of developing cirrhosis and hepatocellular carcinoma in alcohol misusers

scientific article published on 19 October 2019

Genome-Wide Association Studies in Drug-Induced Liver Injury: Step Change in Understanding the Pathogenesis

scientific article

Genome-wide association study of non-alcoholic fatty liver and steatohepatitis in a histologically-characterised cohort

scientific article published on 13 April 2020

Glycaemic, gastrointestinal and appetite responses to breakfast porridges from ancient cereal grains: A MRI pilot study in healthy humans

article

Glycaemic, gastrointestinal, hormonal and appetitive responses to pearl millet or oats porridge breakfasts: a randomised, crossover trial in healthy humans

scientific article published on 01 November 2019

Guidelines on the management of ascites in cirrhosis

scientific article published on 16 October 2020

HLA associations with infliximab-induced liver injury

scientific article published on 06 February 2020

HLA-B*14:01 and HLA-B*35:01 are associated with trimethoprim-sulfamethoxazole induced liver injury

scientific article published on 09 April 2020

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

scientific article

HLA-DRB1*16: 01-DQB1*05: 02 is a novel genetic risk factor for flupirtine-induced liver injury

scientific article published on 9 March 2016

Healthcare costs of transarterial chemoembolization in the treatment of hepatocellular carcinoma

scientific article

Helical CT versus EUS with fine needle aspiration for celiac nodal assessment in patients with esophageal cancer

scientific article published on 01 May 2002

Hepatic adducts, circulating antibodies, and cytokine polymorphisms in patients with diclofenac hepatotoxicity

scientific article

Hepatotoxicity Related to Anti-tuberculosis Drugs: Mechanisms and Management

scientific article published on 20 December 2012

Hepatotoxicity related to antirheumatic drugs ⬇️

scientific article published on January 25, 2011

High serum IgG4 concentrations in patients with sclerosing pancreatitis

scientific article published on 01 July 2001

High-resolution endoscopy and endoscopic ultrasound for evaluation of early neoplasia in Barrett's esophagus

scientific article

Hip fracture risk in patients with alcoholic cirrhosis: A population-based study using English and Danish data

scientific article published on 17 April 2018

How to tackle rising rates of liver disease in the UK

scientific article published in the British Medical Journal

Human leucocyte antigen class II genotype in susceptibility and resistance to co-amoxiclav-induced liver injury

scientific article published on August 2010

Human leukocyte antigen genetic risk factors of drug-induced liver toxicology

scientific article published on 10 December 2014

Immune dysfunction in patients with obstructive jaundice before and after endoscopic retrograde cholangiopancreatography

scientific article published on June 2016

Immunosuppression, IBD, and risk of lymphoma

scientific article published on August 2002

Incidence and Etiology of Drug-Induced Liver Injury in Mainland China

scientific article published on 08 February 2019

Incidence and prevalence of cirrhosis in the United Kingdom, 1992–2001: A general population-based study

scientific article published on 25 June 2008

Incidence of post-ERCP pancreatitis from direct pancreatic juice collection in hereditary pancreatitis and familial pancreatic cancer before and after the introduction of prophylactic pancreatic stents and rectal diclofenac

scientific article published on 01 March 2015

Increased liver fat and glycogen stores after consumption of high versus low glycaemic index food: A randomized crossover study

scholarly article by Stephen Bawden et al published 29 September 2016 in Diabetes, Obesity and Metabolism

Influence of ursodeoxycholic acid on the mortality and malignancy associated with primary biliary cirrhosis: a population-based cohort study.

scientific article

Investigating the effects of an oral fructose challenge on hepatic ATP reserves in healthy volunteers: A (31)P MRS study

scientific article published on 14 April 2015

Investigation of Oxidative Stress-Related Candidate Genes as Risk Factors for Drug-Induced Liver Injury due to Co-Amoxiclav

scientific article published on 06 January 2020

Is clinical examination an art?

scientific article published on 01 February 2000

JournalScan

article published in 2003

JournalScan

JournalScan.

scientific article published in July 2003

Lack of efficacy of an inhibitor of PDE4 in phase 1 and 2 trials of patients with nonalcoholic steatohepatitis

scientific article published on 12 February 2014

Lesson of the month. Beware the eosinophils

scientific article published on 26 May 2007

Limited contribution of common genetic variants to risk for liver injury due to a variety of drugs ⬇️

scientific article published on November 1, 2012

Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study

scientific article published on 19 November 2015

Long-Term Pioglitazone Treatment for Patients With Nonalcoholic Steatohepatitis

scientific article published on 01 February 2017

Lower gut microbiome diversity and higher abundance of proinflammatory genus Collinsella are associated with biopsy-proven nonalcoholic steatohepatitis

scientific article published on 07 November 2019

Mass spectrometric characterization of circulating covalent protein adducts derived from a drug acyl glucuronide metabolite: multiple albumin adductions in diclofenac patients

scientific article

Measurement of carbohydrate-deficient transferrin (CDT) in a general medical clinic: is this test useful in assessing alcohol consumption

scientific article published in May 1998

Mind the gap

scientific article published on 01 December 2010

Minocycline hepatotoxicity: Clinical characterization and identification of HLA-B∗35:02 as a risk factor.

scientific article published on 17 March 2017

Mitochondrial DNA does not contribute to the heritability of non-alcoholic fatty liver disease

scientific article published on 01 October 2010

Monitoring liver function during methotrexate therapy for psoriasis: are routine biopsies really necessary?

scientific article

Monitoring methotrexate-induced hepatic fibrosis in patients with psoriasis: are serial liver biopsies justified?

scientific article published in February 2004

Monozygotic twins with NASH cirrhosis: cumulative effect of multiple single nucleotide polymorphisms?

Multi-organ assessment of compensated cirrhosis patients using quantitative magnetic resonance imaging

scientific article published on 08 June 2018

Multicenter experience from the UK and Ireland of use of lumen-apposing metal stent for transluminal drainage of pancreatic fluid collections.

scientific article published on 28 February 2018

N-acetyltransferase 2 (NAT2) genotype as a risk factor for development of drug-induced liver injury relating to antituberculosis drug treatment in a mixed-ethnicity patient group

article

Natural history of histologically proven alcohol-related liver disease: A systematic review

scientific article published on 05 June 2019

No difference between high-fructose and high-glucose diets on liver triacylglycerol or biochemistry in healthy overweight men.

scientific article published on 19 July 2013

Non-invasive assessment of portal hypertension using quantitative magnetic resonance imaging

scientific article published on 27 July 2016

Noninvasive markers of fibrosis in nonalcoholic fatty liver disease: Validating the European Liver Fibrosis Panel and exploring simple markers

scientific article

Nonsteroidal anti-inflammatory drug-induced hepatotoxicity

scientific article published on August 2007

Obesity Is the Most Common Risk Factor for Chronic Liver Disease: Results From a Risk Stratification Pathway Using Transient Elastography

scientific article published on 01 November 2019

Obesity and type 2 diabetes are important risk factors underlying previously undiagnosed cirrhosis in general practice: a cross-sectional study using transient elastography.

scientific article

Pharmacogenetic testing in idiosyncratic drug-induced liver injury: current role in clinical practice

scientific article published on 20 April 2015

Polygenic architecture informs potential vulnerability to drug-induced liver injury

scientific article published on 07 September 2020

Portal hypertension secondary to arterio-portal fistulae: two unusual cases

scientific article published on 01 August 1999

Portal inflammation is associated with advanced histological changes in alcoholic and non-alcoholic fatty liver disease

scientific article published on September 2010

Posttransplant Outcome of Lean Compared With Obese Nonalcoholic Steatohepatitis in the United States: The Obesity Paradox

scientific article published on 01 January 2020

Preempting and preventing drug-induced liver injury ⬇️

scientific article published on 01 August 2010

Preoperative drainage in pancreatic cancer

Prevalence and natural history of histologically proven chronic liver disease in a longitudinal cohort of patients with type 1 diabetes

scientific article published on 28 May 2014

Pro-adrenomedullin in acute decompensation of liver cirrhosis: relationship with acute-on-chronic liver failure and short-term survival

scientific article published on 01 June 2020

Randomized, placebo-controlled trial of pioglitazone in nondiabetic subjects with nonalcoholic steatohepatitis

scientific article

Regional anthropometric measures associated with the severity of liver injury in patients with non-alcoholic fatty liver disease

scientific article published on 7 January 2013

Relationship of polymorphism in CYP2C9 to genetic susceptibility to diclofenac-induced hepatitis

scientific article published in August 2000

Reply to: "Hip fracture risk in patients with alcoholic cirrhosis: Do comorbidities and complications matter?"

scientific article published on 10 November 2018

Risk of cardiovascular and cerebrovascular events in primary biliary cirrhosis: a population-based cohort study.

scientific article published on 27 August 2008

Risk of hepatocellular carcinoma among individuals with different aetiologies of cirrhosis: a population-based cohort study

scientific article published on February 2017

Role of polymorphisms in the interleukin-10 gene in determining disease susceptibility and phenotype in inflamatory bowel disease

scientific article published on 01 July 2001

Safety and long term efficacy of porfimer sodium photodynamic therapy in locally advanced biliary tract carcinoma

scientific article

Shared Genetic Risk Factors Across Carbamazepine-Induced Hypersensitivity Reactions

scientific article published on 03 July 2019

Short-term changes observed in multiparametric liver MRI following therapy with direct-acting antivirals in chronic hepatitis C virus patients.

scientific article

Squamous cell carcinoma of the pancreas: report of a case and review of the literature

scientific article

Steering azathioprine safely: lessons from pharmacogenetics

scientific article published on 01 November 2001

Subclinical esophageal peristaltic dysfunction during the early phase following a stroke

scientific article published on 01 February 1999

Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles

scientific article

TM6SF2 rs58542926 influences hepatic fibrosis progression in patients with non-alcoholic fatty liver disease

scientific article

The Evaluation and Use of a Food Frequency Questionnaire Among the Population in Trivandrum, South Kerala, India

scientific article published on 31 January 2020

The XL probe: A luxury or a necessity? Risk stratification in an obese community cohort using transient elastography

scientific article published on 18 April 2018

The antecedents of biliary cancer: a primary care case-control study in the United Kingdom.

scientific article

The communication of a secondary care diagnosis of autoimmune hepatitis to primary care practitioners: a population-based study.

scientific article

The detection of oesophageal varices using a novel, disposable, probe-based transnasal endoscope: a prospective diagnostic pilot study.

scientific article published on 28 April 2016

The effect of exercise training on intrahepatic triglyceride and hepatic insulin sensitivity: a systematic review and meta-analysis

scientific article published on 09 August 2018

The effect of prone positioning with surgical bolsters on liver blood flow in healthy volunteers.

scientific article published on 7 March 2016

The influence of adiposity and acute exercise on circulating hepatokines in normal weight and overweight/obese men.

scientific article published on 8 December 2017

The pathological response to neoadjuvant chemotherapy with FOLFOX-4 for colorectal liver metastases: a comparative study

scientific article published on 06 September 2007

The performance of transient elastography compared to clinical acumen and routine tests - what is the incremental diagnostic value?

scientific article published on 8 November 2012

The phenotype standardization project: improving pharmacogenetic studies of serious adverse drug reactions.

scientific article published on June 2011

The quest for an evidence-based approach to surveillance for methotrexate-related hepatotoxicity: promise and perils

scientific article published on 29 April 2015

The rate of decompensation and clinical progression of disease in people with cirrhosis: a cohort study

scientific article published on 04 October 2010

The utility of scoring systems in predicting early and late mortality in alcoholic hepatitis: whose score is it anyway?

scientific article published on 4 September 2012

To feed or what to feed in cirrhosis?

scientific article published on 06 July 2012

Toll-like receptor 4 status influences hepatic metabolism, although its interaction with a high-fructose, energy, and prebiotic diet remains uncertain

scientific article published in April 2010

Transient elastography for screening of liver fibrosis: Cost-effectiveness analysis from six prospective cohorts in Europe and Asia

scientific article published on 27 August 2019

Upstream and coding region CYP2C9 polymorphisms: correlation with warfarin dose and metabolism

scientific article published in December 2004

Using MRI to study the alterations in liver blood flow, perfusion, and oxygenation in response to physiological stress challenges: Meal, hyperoxia, and hypercapnia

article

Validation of a Model for Identification of Patients With Compensated Cirrhosis at High Risk of Decompensation

scientific article published on 01 February 2019

Validation of terminal peptide of procollagen III for the detection and assessment of nonalcoholic steatohepatitis in patients with nonalcoholic fatty liver disease

scientific article

Validation of the AASLD recommendations for classification of oesophageal varices in clinical practice

scientific article published on 08 December 2019

Visual morphometry and three non-invasive markers in the evaluation of liver fibrosis in chronic liver disease

scientific article published on 12 September 2016

Volixibat in adults with non-alcoholic steatohepatitis: 24-week interim analysis from a randomized, phase II study

scientific article published on 28 March 2020

When acquired thrombophilia mattered

scientific article published in August 2005

When is a herb a drug?

scientific article published on 01 April 2005

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