List of works - Vicky M. Avery

Chemical genetics of Plasmodium falciparum

scientific article (publication date: 20 May 2010)

A novel multiple-stage antimalarial agent that inhibits protein synthesis

scientific article (publication date: 18 June 2015)

Quinolone-3-diarylethers: a new class of antimalarial drug.

scientific article published in March 2013

Identification of inhibitors of Plasmodium falciparum gametocyte development

scientific article published on November 11, 2013

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

scientific article

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

scientific article (publication date: July 2016)

(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium.

scientific article

Advanced cell culture techniques for cancer drug discovery.

scientific article published on 30 May 2014

Diversity-oriented synthesis yields novel multistage antimalarial inhibitors

scientific article (publication date: 7 September 2016)

Identification of MMV malaria box inhibitors of plasmodium falciparum early-stage gametocytes using a luciferase-based high-throughput assay

scientific article

Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum

scientific article

Development of an Alamar Blue viability assay in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427.

scientific article published in October 2009

Development and Optimization of a Novel 384-Well Anti-Malarial Imaging Assay Validated for High-Throughput Screening

scientific article published on January 1, 2012

3,5-Diaryl-2-aminopyridines as a novel class of orally active antimalarials demonstrating single dose cure in mice and clinical candidate potential

scientific article

Flinderoles A-C: antimalarial bis-indole alkaloids from Flindersia species

scientific article

Identification of compounds with anti-proliferative activity against Trypanosoma brucei brucei strain 427 by a whole cell viability based HTS campaign

scientific article

Profiling the anti-protozoal activity of anti-cancer HDAC inhibitors against Plasmodium and Trypanosoma parasites

scientific article published on 20 June 2015

Approaches to protozoan drug discovery: phenotypic screening.

scientific article published on 20 August 2013

Natural Products, Stylissadines A and B, Specific Antagonists of the P2X7Receptor, an Important Inflammatory Target1

article

Antimalarial activity of pyrroloiminoquinones from the Australian marine sponge Zyzzya sp.

scientific article

Alkaloids from the Chinese vine Gnetum montanum

scientific article

Lysine acetylation in sexual stage malaria parasites is a target for antimalarial small molecules.

scientific article

Screening the Medicines for Malaria Venture Pathogen Box across Multiple Pathogens Reclassifies Starting Points for Open-Source Drug Discovery.

scientific article

Screening and hit evaluation of a chemical library against blood-stage Plasmodium falciparum

scientific article

Luciferase-Based, High-Throughput Assay for Screening and Profiling Transmission-Blocking Compounds against Plasmodium falciparum Gametocytes

scientific article published on 19 January 2016

Discovery of HDAC inhibitors with potent activity against multiple malaria parasite life cycle stages

scientific article

Leishmaniasis drug discovery: recent progress and challenges in assay development

scientific article

Evaluation of chemotherapeutics in a three-dimensional breast cancer model

scientific article

Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans

scientific article

7',8'-Dihydroobolactone, a typanocidal alpha-pyrone from the rainforest tree Cryptocarya obovata.

scientific article published on 25 May 2010

Whole-cell in vitro screening for gametocytocidal compounds

scientific article

Clavatadines C-E, guanidine alkaloids from the Australian sponge Suberea clavata.

scientific article published in May 2009

Antimalarial bromotyrosine derivatives from the Australian marine sponge Hyattella sp.

scientific article

Convolutamines I and J, antitrypanosomal alkaloids from the bryozoan Amathia tortusa.

scientific article

Ianthelliformisamines A-C, antibacterial bromotyrosine-derived metabolites from the marine sponge Suberea ianthelliformis.

scientific article

Miniaturized three-dimensional cancer model for drug evaluation

scientific article published on September 2013

Thiaplakortones A-D: antimalarial thiazine alkaloids from the Australian marine sponge Plakortis lita

scientific article

Clavatadine A, a natural product with selective recognition and irreversible inhibition of factor XIa

scientific article

A simple and predictive phenotypic High Content Imaging assay for Plasmodium falciparum mature gametocytes to identify malaria transmission blocking compounds

scientific article published on 10 November 2015

The response of fenestrations, actin, and caveolin-1 to vascular endothelial growth factor in SK Hep1 cells

scientific article

Endiandrin A, a Potent Glucocorticoid Receptor Binder Isolated from the Australian PlantEndiandraanthropophagorum

article

Antitrypanosomal cyclic polyketide peroxides from the Australian marine sponge Plakortis sp.

scientific article published in April 2010

Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles

scientific article published on 14 September 2016

Pseudoceramines A-D, new antibacterial bromotyrosine alkaloids from the marine sponge Pseudoceratina sp.

scientific article published on 17 August 2011

Antimalarial activity of azafluorenone alkaloids from the Australian tree Mitrephora diversifolia

scientific article published in August 2009

Large-scale production of Plasmodium falciparum gametocytes for malaria drug discovery

scientific article published on 28 April 2016

A luciferase based viability assay for ATP detection in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427.

scientific article

Detection of complement protein mRNA in human astrocytes by the polymerase chain reaction

scientific article published in December 1992

In vivo biomarker expression patterns are preserved in 3D cultures of Prostate Cancer

scientific article

Leptoclinidamines A-C, indole alkaloids from the Australian ascidian Leptoclinides durus

scientific article published on April 2009

List of works by Vicky M. Avery

Chemical genetics of Plasmodium falciparum

A novel multiple-stage antimalarial agent that inhibits protein synthesis

Quinolone-3-diarylethers: a new class of antimalarial drug.

Identification of inhibitors of Plasmodium falciparum gametocyte development

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium.

Advanced cell culture techniques for cancer drug discovery.

Diversity-oriented synthesis yields novel multistage antimalarial inhibitors

Identification of MMV malaria box inhibitors of plasmodium falciparum early-stage gametocytes using a luciferase-based high-throughput assay

Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum

Development of an Alamar Blue viability assay in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427.

Development and Optimization of a Novel 384-Well Anti-Malarial Imaging Assay Validated for High-Throughput Screening

3,5-Diaryl-2-aminopyridines as a novel class of orally active antimalarials demonstrating single dose cure in mice and clinical candidate potential

Flinderoles A-C: antimalarial bis-indole alkaloids from Flindersia species

Identification of compounds with anti-proliferative activity against Trypanosoma brucei brucei strain 427 by a whole cell viability based HTS campaign

Profiling the anti-protozoal activity of anti-cancer HDAC inhibitors against Plasmodium and Trypanosoma parasites

Approaches to protozoan drug discovery: phenotypic screening.

Natural Products, Stylissadines A and B, Specific Antagonists of the P2X7Receptor, an Important Inflammatory Target1

Antimalarial activity of pyrroloiminoquinones from the Australian marine sponge Zyzzya sp.

Alkaloids from the Chinese vine Gnetum montanum

Lysine acetylation in sexual stage malaria parasites is a target for antimalarial small molecules.

Screening the Medicines for Malaria Venture Pathogen Box across Multiple Pathogens Reclassifies Starting Points for Open-Source Drug Discovery.

Screening and hit evaluation of a chemical library against blood-stage Plasmodium falciparum

Luciferase-Based, High-Throughput Assay for Screening and Profiling Transmission-Blocking Compounds against Plasmodium falciparum Gametocytes

Discovery of HDAC inhibitors with potent activity against multiple malaria parasite life cycle stages

Leishmaniasis drug discovery: recent progress and challenges in assay development

Evaluation of chemotherapeutics in a three-dimensional breast cancer model

Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans

7',8'-Dihydroobolactone, a typanocidal alpha-pyrone from the rainforest tree Cryptocarya obovata.

Whole-cell in vitro screening for gametocytocidal compounds

Clavatadines C-E, guanidine alkaloids from the Australian sponge Suberea clavata.

Antimalarial bromotyrosine derivatives from the Australian marine sponge Hyattella sp.

Convolutamines I and J, antitrypanosomal alkaloids from the bryozoan Amathia tortusa.

Ianthelliformisamines A-C, antibacterial bromotyrosine-derived metabolites from the marine sponge Suberea ianthelliformis.

Miniaturized three-dimensional cancer model for drug evaluation

Thiaplakortones A-D: antimalarial thiazine alkaloids from the Australian marine sponge Plakortis lita

Clavatadine A, a natural product with selective recognition and irreversible inhibition of factor XIa

A simple and predictive phenotypic High Content Imaging assay for Plasmodium falciparum mature gametocytes to identify malaria transmission blocking compounds

The response of fenestrations, actin, and caveolin-1 to vascular endothelial growth factor in SK Hep1 cells

Endiandrin A, a Potent Glucocorticoid Receptor Binder Isolated from the Australian PlantEndiandraanthropophagorum

Antitrypanosomal cyclic polyketide peroxides from the Australian marine sponge Plakortis sp.

Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles

Pseudoceramines A-D, new antibacterial bromotyrosine alkaloids from the marine sponge Pseudoceratina sp.

Antimalarial activity of azafluorenone alkaloids from the Australian tree Mitrephora diversifolia

Large-scale production of Plasmodium falciparum gametocytes for malaria drug discovery

A luciferase based viability assay for ATP detection in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427.

Detection of complement protein mRNA in human astrocytes by the polymerase chain reaction

In vivo biomarker expression patterns are preserved in 3D cultures of Prostate Cancer

Leptoclinidamines A-C, indole alkaloids from the Australian ascidian Leptoclinides durus