List of works - Vicky M. Avery

Development and application of a sensitive, phenotypic, high-throughput image-based assay to identify compound activity against Trypanosoma cruzi amastigotes

scientific article

N-aryl-2-aminobenzimidazoles: novel, efficacious, antimalarial lead compounds

scientific article published on 21 July 2014

Isolation, structure elucidation and cytotoxic evaluation of endiandrin B from the Australian rainforest plant Endiandra anthropophagorum

scientific article

Two-pronged attack: dual inhibition of Plasmodium falciparum M1 and M17 metalloaminopeptidases by a novel series of hydroxamic acid-based inhibitors

scientific article

Copper, nickel, and zinc cyclam-amino acid and cyclam-peptide complexes may be synthesized with "click" chemistry and are noncytotoxic

scientific article

Euodenine A: A Small-Molecule Agonist of Human TLR4

scientific article published on 07 February 2014

Synthesis, antimalarial properties, and SAR studies of alkoxyurea-based HDAC inhibitors.

scientific article published on 4 February 2014

A new quinoline epoxide from the Australian plant Drummondita calida

scientific article

Antitrypanosomal pyridoacridine alkaloids from the Australian ascidian Polysyncraton echinatum

article

Tomentosones A and B, hexacyclic phloroglucinol derivatives from the Thai shrub Rhodomyrtus tomentosa

scientific article published on 28 November 2011

Doxorubicin resistance in breast cancer cells is mediated by extracellular matrix proteins

scientific article published on 6 January 2018

Polydiscamides B-D from a marine sponge Ircinia sp. as potent human sensory neuron-specific G protein coupled receptor agonists

scientific article

Antiparasitic activity of alkaloids from plant species of Papua New Guinea and Australia.

scientific article published on 26 June 2010

Repositioning: the fast track to new anti-malarial medicines?

scientific article

Vanillic acid derivatives from the green algae Cladophora socialis as potent protein tyrosine phosphatase 1B inhibitors

scientific article published on 20 October 2007

(+)-7-Bromotrypargine: an antimalarial β-carboline from the Australian marine sponge Ancorina sp

article

Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy

scientific article published on 10 September 2016

Iotrochamides A and B, antitrypanosomal compounds from the Australian marine sponge Iotrochota sp.

scientific article published on 17 May 2012

Spermatinamine, the first natural product inhibitor of isoprenylcysteine carboxyl methyltransferase, a new cancer target.

scientific article published on 16 October 2007

Screening a Natural Product-Based Library against Kinetoplastid Parasites.

scientific article published on 12 October 2017

Aplysamine 6, an alkaloidal inhibitor of Isoprenylcysteine carboxyl methyltransferase from the sponge Pseudoceratina sp.

scientific article

Niphatoxin C, a cytotoxic tripyridine alkaloid from Callyspongia sp.

scientific article published on 21 November 2007

Antimalarial benzylisoquinoline alkaloid from the rainforest tree Doryphora sassafras

scientific article published in August 2009

Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides

scientific article published on 22 August 2016

Pyridyl benzamides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei.

scientific article

Small-molecule inhibitors of the cancer target, isoprenylcysteine carboxyl methyltransferase, from Hovea parvicalyx

scientific article published on 06 May 2008

A novel approach for the discovery of chemically diverse anti-malarial compounds targeting the Plasmodium falciparum Coenzyme A synthesis pathway

scientific article

Surface phagocytosis and host defence in the peritoneal cavity during continuous ambulatory peritoneal dialysis

scientific article published on 01 March 1990

The isolation, structure determination and cytotoxicity of the new fungal metabolite, trichodermamide C

scientific article published on 08 April 2008

Acrotrione: An Oxidized Xanthene from the Roots of Acronychia pubescens

scientific article published on 13 March 2019

(-)-Dibromophakellin: an alpha2B adrenoceptor agonist isolated from the Australian marine sponge, Acanthella costata

scientific article

Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions

scientific article

Aplidiopsamine A, an antiplasmodial alkaloid from the temperate Australian ascidian, Aplidiopsis confluata

scientific article published on 3 November 2010

Splenic retention of Plasmodium falciparum gametocytes to block the transmission of malaria

scientific article published on 4 May 2015

Albopunctatone, an antiplasmodial anthrone-anthraquinone from the Australian ascidian Didemnum albopunctatum

scientific article published on 8 June 2012

Bone-stromal cells up-regulate tumourigenic markers in a tumour-stromal 3D model of prostate cancer

scientific article published on 30 September 2013

Solving the supply of resveratrol tetramers from Papua New Guinean rainforest anisoptera species that inhibit bacterial type III secretion systems

scientific article

Medicinal chemistry optimization of antiplasmodial imidazopyridazine hits from high throughput screening of a SoftFocus kinase library: part 1.

scientific article

Trypanocidal activity of marine natural products

scientific article

Wilsoniamines A and B: novel alkaloids from the temperate Australian bryozoan, Amathia wilsoni

article

Optimization of 2-Anilino 4-Amino Substituted Quinazolines into Potent Antimalarial Agents with Oral in Vivo Activity

scientific article published on 12 January 2017

Antibacterial properties of breast milk: Requirements for surface phagocytosis and chemiluminescence

scientific article published on December 1, 1991

Mechanical clearance of red blood cells by the human spleen: Potential therapeutic applications of a biomimetic RBC filtration method

scientific article published on 29 June 2015

Citronamides A and B, tetrapeptides from the Australian sponge Citronia astra

scientific article published in April 2009

The functional antagonist Met-RANTES: a modified agonist that induces differential CCR5 trafficking

scientific article published on 14 May 2009

SC83288 is a clinical development candidate for the treatment of severe malaria.

scientific article published on 31 January 2017

Chemokine receptor expression on integrin-mediated stellate projections of prostate cancer cells in 3D culture

scientific article published on 3 August 2013

Hexahydroquinolines are antimalarial candidates with potent blood-stage and transmission-blocking activity

scientific article published on 14 August 2017

Antimalarial activity of natural product extracts from Papua New Guinean and Australian plants against Plasmodium falciparum

scientific article

3-(Oxazolo[4,5-b]pyridin-2-yl)anilides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei, the causative agent for human African trypanosomiasis.

scientific article published on 16 May 2013

List of works by Vicky M. Avery

Development and application of a sensitive, phenotypic, high-throughput image-based assay to identify compound activity against Trypanosoma cruzi amastigotes

N-aryl-2-aminobenzimidazoles: novel, efficacious, antimalarial lead compounds

Isolation, structure elucidation and cytotoxic evaluation of endiandrin B from the Australian rainforest plant Endiandra anthropophagorum

Two-pronged attack: dual inhibition of Plasmodium falciparum M1 and M17 metalloaminopeptidases by a novel series of hydroxamic acid-based inhibitors

Copper, nickel, and zinc cyclam-amino acid and cyclam-peptide complexes may be synthesized with "click" chemistry and are noncytotoxic

Euodenine A: A Small-Molecule Agonist of Human TLR4

Synthesis, antimalarial properties, and SAR studies of alkoxyurea-based HDAC inhibitors.

A new quinoline epoxide from the Australian plant Drummondita calida

Antitrypanosomal pyridoacridine alkaloids from the Australian ascidian Polysyncraton echinatum

Tomentosones A and B, hexacyclic phloroglucinol derivatives from the Thai shrub Rhodomyrtus tomentosa

Doxorubicin resistance in breast cancer cells is mediated by extracellular matrix proteins

Polydiscamides B-D from a marine sponge Ircinia sp. as potent human sensory neuron-specific G protein coupled receptor agonists

Antiparasitic activity of alkaloids from plant species of Papua New Guinea and Australia.

Repositioning: the fast track to new anti-malarial medicines?

Vanillic acid derivatives from the green algae Cladophora socialis as potent protein tyrosine phosphatase 1B inhibitors

(+)-7-Bromotrypargine: an antimalarial β-carboline from the Australian marine sponge Ancorina sp

Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy

Iotrochamides A and B, antitrypanosomal compounds from the Australian marine sponge Iotrochota sp.

Spermatinamine, the first natural product inhibitor of isoprenylcysteine carboxyl methyltransferase, a new cancer target.

Screening a Natural Product-Based Library against Kinetoplastid Parasites.

Aplysamine 6, an alkaloidal inhibitor of Isoprenylcysteine carboxyl methyltransferase from the sponge Pseudoceratina sp.

Niphatoxin C, a cytotoxic tripyridine alkaloid from Callyspongia sp.

Antimalarial benzylisoquinoline alkaloid from the rainforest tree Doryphora sassafras

Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides

Pyridyl benzamides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei.

Small-molecule inhibitors of the cancer target, isoprenylcysteine carboxyl methyltransferase, from Hovea parvicalyx

A novel approach for the discovery of chemically diverse anti-malarial compounds targeting the Plasmodium falciparum Coenzyme A synthesis pathway

Surface phagocytosis and host defence in the peritoneal cavity during continuous ambulatory peritoneal dialysis

The isolation, structure determination and cytotoxicity of the new fungal metabolite, trichodermamide C

Acrotrione: An Oxidized Xanthene from the Roots of Acronychia pubescens

(-)-Dibromophakellin: an alpha2B adrenoceptor agonist isolated from the Australian marine sponge, Acanthella costata

Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions

Aplidiopsamine A, an antiplasmodial alkaloid from the temperate Australian ascidian, Aplidiopsis confluata

Splenic retention of Plasmodium falciparum gametocytes to block the transmission of malaria

Albopunctatone, an antiplasmodial anthrone-anthraquinone from the Australian ascidian Didemnum albopunctatum

Bone-stromal cells up-regulate tumourigenic markers in a tumour-stromal 3D model of prostate cancer

Solving the supply of resveratrol tetramers from Papua New Guinean rainforest anisoptera species that inhibit bacterial type III secretion systems

Medicinal chemistry optimization of antiplasmodial imidazopyridazine hits from high throughput screening of a SoftFocus kinase library: part 1.

Trypanocidal activity of marine natural products

Wilsoniamines A and B: novel alkaloids from the temperate Australian bryozoan, Amathia wilsoni

Optimization of 2-Anilino 4-Amino Substituted Quinazolines into Potent Antimalarial Agents with Oral in Vivo Activity

Antibacterial properties of breast milk: Requirements for surface phagocytosis and chemiluminescence

Mechanical clearance of red blood cells by the human spleen: Potential therapeutic applications of a biomimetic RBC filtration method

Citronamides A and B, tetrapeptides from the Australian sponge Citronia astra

The functional antagonist Met-RANTES: a modified agonist that induces differential CCR5 trafficking

SC83288 is a clinical development candidate for the treatment of severe malaria.

Chemokine receptor expression on integrin-mediated stellate projections of prostate cancer cells in 3D culture

Hexahydroquinolines are antimalarial candidates with potent blood-stage and transmission-blocking activity

Antimalarial activity of natural product extracts from Papua New Guinean and Australian plants against Plasmodium falciparum

3-(Oxazolo[4,5-b]pyridin-2-yl)anilides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei, the causative agent for human African trypanosomiasis.