List of works - David W. Threadgill

The Collaborative Cross, a community resource for the genetic analysis of complex traits

article

Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function

scientific article

Mouse behavioral tasks relevant to autism: phenotypes of 10 inbred strains

scientific article

EGF receptor is required for KRAS-induced pancreatic tumorigenesis

scientific journal article

Genetic analysis of complex traits in the emerging Collaborative Cross

scientific article

Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer

scientific article published on January 2007

The nature and identification of quantitative trait loci: a community's view

scientific article published in November 2003

The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics

scientific article published on June 2008

The polymorphism architecture of mouse genetic resources elucidated using genome-wide resequencing data: implications for QTL discovery and systems genetics

scientific article

Luteinizing hormone-dependent activation of the epidermal growth factor network is essential for ovulation

scientific article published on 28 December 2006

EGFR signaling promotes TGFβ-dependent renal fibrosis

scientific article published on 17 November 2011

Genetic dissection of complex and quantitative traits: from fantasy to reality via a community effort

scientific article

A Gnotobiotic Mouse Model Demonstrates That Dietary Fiber Protects against Colorectal Tumorigenesis in a Microbiota- and Butyrate-Dependent Manner

scientific article published on September 29, 2014

Modeling host genetic regulation of influenza pathogenesis in the collaborative cross

scientific article (publication date: February 2013)

Role of the Angiotensin Type 2 Receptor Gene in Congenital Anomalies of the Kidney and Urinary Tract, CAKUT, of Mice and Men

article

Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis

scientific article

Activation of the epidermal growth factor receptor signal transduction pathway stimulates tyrosine phosphorylation of protein kinase C delta

scientific article published on 01 March 1996

Genealogy of the 129 inbred strains: 129/SvJ is a contaminated inbred strain

scientific article published on 01 June 1997

Analyses of allele-specific gene expression in highly divergent mouse crosses identifies pervasive allelic imbalance.

scientific article

Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans

scientific article published on 05 May 2009

Status and access to the Collaborative Cross population.

scientific article

SNP array profiling of mouse cell lines identifies their strains of origin and reveals cross-contamination and widespread aneuploidy

scientific article

Genetics of dark skin in mice

scientific article

Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation

scientific article

The collaborative cross: a recombinant inbred mouse population for the systems genetic era.

scientific article published on January 2011

Cardiac response to pressure overload in 129S1/SvImJ and C57BL/6J mice: temporal- and background-dependent development of concentric left ventricular hypertrophy

scientific article published on 15 December 2006

Requirement of epidermal growth factor receptor for hyperplasia induced by E5, a high-risk human papillomavirus oncogene

scientific article published on August 2005

Ten years of the Collaborative Cross

scientific article published on February 2012

Large-scale gene expression differences across brain regions and inbred strains correlate with a behavioral phenotype

scientific article

Characterization of a common deletion polymorphism of the UGT2B17 gene linked to UGT2B15

article

High expression of ErbB family members and their ligands in lung adenocarcinomas that are sensitive to inhibition of epidermal growth factor receptor

scientific article published in December 2005

Ten years of the collaborative cross

scientific article

Expression quantitative trait Loci for extreme host response to influenza a in pre-collaborative cross mice

scientific article published on February 2012

Tumor fibroblast-derived epiregulin promotes growth of colitis-associated neoplasms through ERK

scientific article published on 15 March 2013

Genome Wide Identification of SARS-CoV Susceptibility Loci Using the Collaborative Cross

scientific article published on 9 October 2015

Quantitative trait locus analysis using recombinant inbred intercrosses: theoretical and empirical considerations

scientific article

Quantitative PCR assays for mouse enteric flora reveal strain-dependent differences in composition that are influenced by the microenvironment

article

Epiregulin is not essential for development of intestinal tumors but is required for protection from intestinal damage

scientific article published on October 2004

Comparative genomic sequence analysis and isolation of human and mouse alternative EGFR transcripts encoding truncated receptor isoforms.

scientific article published on 01 January 2001

Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal

scientific article

Azoxymethane Is a Genetic Background-Dependent Colorectal Tumor Initiator and Promoter in Mice: Effects of Dose, Route, and Diet

scientific article published on 08 September 2005

Genetic analysis of hematological parameters in incipient lines of the collaborative cross

scientific article published on February 2012

Generation and validation of mice carrying a conditional allele of the epidermal growth factor receptor

scientific article

Architecture of energy balance traits in emerging lines of the Collaborative Cross

scientific article

EGFR regulates the expression of keratinocyte-derived granulocyte/macrophage colony-stimulating factor in vitro and in vivo

scientific article published on 5 November 2009

Using the emerging Collaborative Cross to probe the immune system

scientific article

Inferring missing genotypes in large SNP panels using fast nearest-neighbor searches over sliding windows

scientific article published on July 2007

Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium

scientific article published on 17 August 2009

Population-based discovery of toxicogenomics biomarkers for hepatotoxicity using a laboratory strain diversity panel

scientific article published on 06 May 2009

Genome-level analysis of genetic regulation of liver gene expression networks

scientific article

List of works by David W. Threadgill

The Collaborative Cross, a community resource for the genetic analysis of complex traits

Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function

Mouse behavioral tasks relevant to autism: phenotypes of 10 inbred strains

EGF receptor is required for KRAS-induced pancreatic tumorigenesis

Genetic analysis of complex traits in the emerging Collaborative Cross

Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer

The nature and identification of quantitative trait loci: a community's view

The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics

The polymorphism architecture of mouse genetic resources elucidated using genome-wide resequencing data: implications for QTL discovery and systems genetics

Luteinizing hormone-dependent activation of the epidermal growth factor network is essential for ovulation

EGFR signaling promotes TGFβ-dependent renal fibrosis

Genetic dissection of complex and quantitative traits: from fantasy to reality via a community effort

A Gnotobiotic Mouse Model Demonstrates That Dietary Fiber Protects against Colorectal Tumorigenesis in a Microbiota- and Butyrate-Dependent Manner

Modeling host genetic regulation of influenza pathogenesis in the collaborative cross

Role of the Angiotensin Type 2 Receptor Gene in Congenital Anomalies of the Kidney and Urinary Tract, CAKUT, of Mice and Men

Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis

Activation of the epidermal growth factor receptor signal transduction pathway stimulates tyrosine phosphorylation of protein kinase C delta

Genealogy of the 129 inbred strains: 129/SvJ is a contaminated inbred strain

Analyses of allele-specific gene expression in highly divergent mouse crosses identifies pervasive allelic imbalance.

Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans

Status and access to the Collaborative Cross population.

SNP array profiling of mouse cell lines identifies their strains of origin and reveals cross-contamination and widespread aneuploidy

Genetics of dark skin in mice

Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation

The collaborative cross: a recombinant inbred mouse population for the systems genetic era.

Cardiac response to pressure overload in 129S1/SvImJ and C57BL/6J mice: temporal- and background-dependent development of concentric left ventricular hypertrophy

Requirement of epidermal growth factor receptor for hyperplasia induced by E5, a high-risk human papillomavirus oncogene

Ten years of the Collaborative Cross

Large-scale gene expression differences across brain regions and inbred strains correlate with a behavioral phenotype

Characterization of a common deletion polymorphism of the UGT2B17 gene linked to UGT2B15

High expression of ErbB family members and their ligands in lung adenocarcinomas that are sensitive to inhibition of epidermal growth factor receptor

Ten years of the collaborative cross

Expression quantitative trait Loci for extreme host response to influenza a in pre-collaborative cross mice

Tumor fibroblast-derived epiregulin promotes growth of colitis-associated neoplasms through ERK

Genome Wide Identification of SARS-CoV Susceptibility Loci Using the Collaborative Cross

Quantitative trait locus analysis using recombinant inbred intercrosses: theoretical and empirical considerations

Quantitative PCR assays for mouse enteric flora reveal strain-dependent differences in composition that are influenced by the microenvironment

Epiregulin is not essential for development of intestinal tumors but is required for protection from intestinal damage

Comparative genomic sequence analysis and isolation of human and mouse alternative EGFR transcripts encoding truncated receptor isoforms.

Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal

Azoxymethane Is a Genetic Background-Dependent Colorectal Tumor Initiator and Promoter in Mice: Effects of Dose, Route, and Diet

Genetic analysis of hematological parameters in incipient lines of the collaborative cross

Generation and validation of mice carrying a conditional allele of the epidermal growth factor receptor

Architecture of energy balance traits in emerging lines of the Collaborative Cross

EGFR regulates the expression of keratinocyte-derived granulocyte/macrophage colony-stimulating factor in vitro and in vivo

Using the emerging Collaborative Cross to probe the immune system

Inferring missing genotypes in large SNP panels using fast nearest-neighbor searches over sliding windows

Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium

Population-based discovery of toxicogenomics biomarkers for hepatotoxicity using a laboratory strain diversity panel

Genome-level analysis of genetic regulation of liver gene expression networks