List of works - David W. Threadgill

Wa5 is a novel ENU-induced antimorphic allele of the epidermal growth factor receptor

scientific article published in July 2004

Epidermal growth factor receptor plays an anabolic role in bone metabolism in vivo

scientific article

A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2

scientific article

Interstrain differences in the liver effects of trichloroethylene in a multistrain panel of inbred mice

scientific article

Sensitivity to hepatotoxicity due to epigallocatechin gallate is affected by genetic background in diversity outbred mice

scientific article

PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1

scientific article published on 14 February 2009

Reduced EGFR causes abnormal valvular differentiation leading to calcific aortic stenosis and left ventricular hypertrophy in C57BL/6J but not 129S1/SvImJ mice

scientific article published on 15 May 2009

Identification of MAGI-3 as a transforming growth factor-alpha tail binding protein

scientific article

The epidermal growth factor receptor critically regulates endometrial function during early pregnancy

scientific article

Cross-talk between epidermal growth factor receptor and protein kinase C during calcium-induced differentiation of keratinocytes

scientific article published on June 2000

Toxicogenetics: population-based testing of drug and chemical safety in mouse models

scientific article

Characterization of Variability in Toxicokinetics and Toxicodynamics of Tetrachloroethylene Using the Collaborative Cross Mouse Population.

scientific article published on 30 May 2017

Phenotypic variation resulting from a deficiency of epidermal growth factor receptor in mice is caused by extensive genetic heterogeneity that can be genetically and molecularly partitioned

scientific article

ERBBs in the gastrointestinal tract: recent progress and new perspectives

scientific article

Editor's Highlight: Collaborative Cross Mouse Population Enables Refinements to Characterization of the Variability in Toxicokinetics of Trichloroethylene and Provides Genetic Evidence for the Role of PPAR Pathway in Its Oxidative Metabolism.

scientific article published on 27 March 2017

The PGE2 EP3 Receptor Regulates Diet-Induced Adiposity in Male Mice

scientific article

Targeted inactivation of EGF receptor inhibits renal collecting duct development and function.

scientific article

The gastrointestinal microbiome: a malleable, third genome of mammals

scientific article

Maternal dioxin exposure combined with a diet high in fat increases mammary cancer incidence in mice.

scientific article

Mechanism for prevention of alcohol-induced liver injury by dietary methyl donors

scientific article

Deficient NRG1-ERBB signaling alters social approach: relevance to genetic mouse models of schizophrenia

scientific article

Genotype X diet interactions in mice predisposed to mammary cancer: II. Tumors and metastasis

scientific article published on 21 February 2008

Dietary fat alters body composition, mammary development, and cytochrome p450 induction after maternal TCDD exposure in DBA/2J mice with low-responsive aryl hydrocarbon receptors

scientific article published on 18 May 2009

Animal models of autism spectrum disorders: information for neurotoxicologists

scientific article

Genome-wide association mapping of loci for antipsychotic-induced extrapyramidal symptoms in mice

scientific article

Chronic pharmacologic inhibition of EGFR leads to cardiac dysfunction in C57BL/6J mice

scientific article published on 07 March 2008

Epidermal growth factor receptor is required for colonic tumor promotion by dietary fat in the azoxymethane/dextran sulfate sodium model: roles of transforming growth factor-{alpha} and PTGS2.

scientific article

Phosphatidylinositol 3-kinase signaling determines kidney size

scientific article published on 18 May 2015

Epidermal growth factor receptor plays a role in the regulation of liver and plasma lipid levels in adult male mice

scientific article published on 09 January 2014

The EGFR is required for proper innervation to the skin

scientific article published on 02 October 2008

Murine models of colorectal cancer

scientific article

Loss of hepatocyte EGFR has no effect alone but exacerbates carbon tetrachloride-induced liver injury and impairs regeneration in hepatocyte Met-deficient mice

scientific article

Replication and narrowing of gene expression quantitative trait loci using inbred mice

scientific article published on 17 July 2009

Modeling the cancer patient with genetically engineered mice: prediction of toxicity from molecule-targeted therapies

scientific article published on February 2004

Placental and embryonic growth restriction in mice with reduced function epidermal growth factor receptor alleles

scientific article published on 29 June 2009

The untapped potential of genetically engineered mouse models in chemoprevention research: opportunities and challenges

scientific article published on August 2008

Genetic mapping of a Ptch1-associated rhabdomyosarcoma susceptibility locus on mouse chromosome 2

scientific article published on 01 November 2004

Parent-of-origin effects on cardiac response to pressure overload in mice

scientific article published on 26 June 2009

Flat Colorectal Cancers Are Genetically Determined and Progress to Invasion without Going through a Polypoid Stage

scientific article published on 01 December 2007

Epiregulin-dependent amphiregulin expression and ERBB2 signaling are involved in luteinizing hormone-induced paracrine signaling pathways in mouse ovary

scientific article published on 13 January 2011

TreeQA: quantitative genome wide association mapping using local perfect phylogeny trees.

scientific article published on January 2009

Bayesian multiple quantitative trait loci mapping for complex traits using markers of the entire genome

scientific article

Conditional inactivation of TNFα-converting enzyme in chondrocytes results in an elongated growth plate and shorter long bones

scientific article

Dietary fat alters pulmonary metastasis of mammary cancers through cancer autonomous and non-autonomous changes in gene expression

article

Mouse breast cancer model-dependent changes in metabolic syndrome-associated phenotypes caused by maternal dioxin exposure and dietary fat.

scientific article published on 07 October 2008

MicroRNA expression in the livers of inbred mice

scientific article

Impact of Nonalcoholic Fatty Liver Disease on Toxicokinetics of Tetrachloroethylene in Mice.

scientific article published in February 2017

Differential expression of the full-length and truncated forms of the epidermal growth factor receptor in the preimplantation mouse uterus and blastocyst

scientific article published on 01 April 1996

Placental overgrowth and fertility defects in mice with a hypermorphic allele of epidermal growth factor receptor

scientific article published on 23 May 2009

Modeling cancer patient populations in mice: complex genetic and environmental factors

scientific article published on January 2008

List of works by David W. Threadgill

Wa5 is a novel ENU-induced antimorphic allele of the epidermal growth factor receptor

Epidermal growth factor receptor plays an anabolic role in bone metabolism in vivo

A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2

Interstrain differences in the liver effects of trichloroethylene in a multistrain panel of inbred mice

Sensitivity to hepatotoxicity due to epigallocatechin gallate is affected by genetic background in diversity outbred mice

PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1

Reduced EGFR causes abnormal valvular differentiation leading to calcific aortic stenosis and left ventricular hypertrophy in C57BL/6J but not 129S1/SvImJ mice

Identification of MAGI-3 as a transforming growth factor-alpha tail binding protein

The epidermal growth factor receptor critically regulates endometrial function during early pregnancy

Cross-talk between epidermal growth factor receptor and protein kinase C during calcium-induced differentiation of keratinocytes

Toxicogenetics: population-based testing of drug and chemical safety in mouse models

Characterization of Variability in Toxicokinetics and Toxicodynamics of Tetrachloroethylene Using the Collaborative Cross Mouse Population.

Phenotypic variation resulting from a deficiency of epidermal growth factor receptor in mice is caused by extensive genetic heterogeneity that can be genetically and molecularly partitioned

ERBBs in the gastrointestinal tract: recent progress and new perspectives

Editor's Highlight: Collaborative Cross Mouse Population Enables Refinements to Characterization of the Variability in Toxicokinetics of Trichloroethylene and Provides Genetic Evidence for the Role of PPAR Pathway in Its Oxidative Metabolism.

The PGE2 EP3 Receptor Regulates Diet-Induced Adiposity in Male Mice

Targeted inactivation of EGF receptor inhibits renal collecting duct development and function.

The gastrointestinal microbiome: a malleable, third genome of mammals

Maternal dioxin exposure combined with a diet high in fat increases mammary cancer incidence in mice.

Mechanism for prevention of alcohol-induced liver injury by dietary methyl donors

Deficient NRG1-ERBB signaling alters social approach: relevance to genetic mouse models of schizophrenia

Genotype X diet interactions in mice predisposed to mammary cancer: II. Tumors and metastasis

Dietary fat alters body composition, mammary development, and cytochrome p450 induction after maternal TCDD exposure in DBA/2J mice with low-responsive aryl hydrocarbon receptors

Animal models of autism spectrum disorders: information for neurotoxicologists

Genome-wide association mapping of loci for antipsychotic-induced extrapyramidal symptoms in mice

Chronic pharmacologic inhibition of EGFR leads to cardiac dysfunction in C57BL/6J mice

Epidermal growth factor receptor is required for colonic tumor promotion by dietary fat in the azoxymethane/dextran sulfate sodium model: roles of transforming growth factor-{alpha} and PTGS2.

Phosphatidylinositol 3-kinase signaling determines kidney size

Epidermal growth factor receptor plays a role in the regulation of liver and plasma lipid levels in adult male mice

The EGFR is required for proper innervation to the skin

Murine models of colorectal cancer

Loss of hepatocyte EGFR has no effect alone but exacerbates carbon tetrachloride-induced liver injury and impairs regeneration in hepatocyte Met-deficient mice

Replication and narrowing of gene expression quantitative trait loci using inbred mice

Modeling the cancer patient with genetically engineered mice: prediction of toxicity from molecule-targeted therapies

Placental and embryonic growth restriction in mice with reduced function epidermal growth factor receptor alleles

The untapped potential of genetically engineered mouse models in chemoprevention research: opportunities and challenges

Genetic mapping of a Ptch1-associated rhabdomyosarcoma susceptibility locus on mouse chromosome 2

Parent-of-origin effects on cardiac response to pressure overload in mice

Flat Colorectal Cancers Are Genetically Determined and Progress to Invasion without Going through a Polypoid Stage

Epiregulin-dependent amphiregulin expression and ERBB2 signaling are involved in luteinizing hormone-induced paracrine signaling pathways in mouse ovary

TreeQA: quantitative genome wide association mapping using local perfect phylogeny trees.

Bayesian multiple quantitative trait loci mapping for complex traits using markers of the entire genome

Conditional inactivation of TNFα-converting enzyme in chondrocytes results in an elongated growth plate and shorter long bones

Dietary fat alters pulmonary metastasis of mammary cancers through cancer autonomous and non-autonomous changes in gene expression

Mouse breast cancer model-dependent changes in metabolic syndrome-associated phenotypes caused by maternal dioxin exposure and dietary fat.

MicroRNA expression in the livers of inbred mice

Impact of Nonalcoholic Fatty Liver Disease on Toxicokinetics of Tetrachloroethylene in Mice.

Differential expression of the full-length and truncated forms of the epidermal growth factor receptor in the preimplantation mouse uterus and blastocyst

Placental overgrowth and fertility defects in mice with a hypermorphic allele of epidermal growth factor receptor

Modeling cancer patient populations in mice: complex genetic and environmental factors