List of works - Nushin Aghajari

A flexible loop at the dimer interface is a part of the active site of the adjacent monomer of Escherichia coli orotate phosphoribosyltransferase

scientific article

Active site coupling in Plasmodium falciparum GMP synthetase is triggered by domain rotation

scientific article

An enzyme family reunion — similarities, differences and eccentricities in actions on α-glucans

Biased mutagenesis in the N-terminal region by degenerate oligonucleotide gene shuffling enhances secretory expression of barley alpha-amylase 2 in yeast

scientific article

C-terminal residues regulate localization and function of the antiapoptotic protein Bfl-1.

scientific article published on 15 September 2009

Crystal structures of a psychrophilic metalloprotease reveal new insights into catalysis by cold-adapted proteases

scientific article (publication date: March 2003)

Crystallization and preliminary X-ray diffraction studies on the Apo form of orotate phosphoribosyltransferase from Escherichia coli.

scientific article

Diffraction anisotropy falloff in the direction of the detergent belt for two centered monoclinic crystals of OmpF

scientific article

Efficient bioconversion of lactose in milk and whey: immobilization and biochemical characterization of a beta-galactosidase from the dairy Streptococcus thermophilus LMD9 strain.

scientific article published on 28 May 2010

Engineered glucose isomerase from Streptomyces sp. SK is resistant to Ca²⁺ inhibition and Co²⁺ independent

scientific article published on 4 December 2011

Engineering of the alpha-amylase from Geobacillus stearothermophilus US100 for detergent incorporation

scientific article

Enhancement of the thermostability and the catalytic efficiency of Bacillus pumilus CBS protease by site-directed mutagenesis

scientific article published on 21 January 2010

Enhancement of the thermostability of the maltogenic amylase MAUS149 by Gly312Ala and Lys436Arg substitutions.

scientific article

Expanding the Kinome World: A New Protein Kinase Family Widely Conserved in Bacteria.

scientific article published on 7 September 2017

Exploring the acidotolerance of beta-galactosidase from Lactobacillus delbrueckii subsp. bulgaricus: an attractive enzyme for lactose bioconversion

scientific article published on 26 September 2009

Expression, purification and preliminary crystallographic studies of alpha-amylase isozyme 1 from barley seeds

scientific article published on 22 March 2002

Expression, purification, crystallization and preliminary X-ray crystallographic studies of a psychrophilic cellulase from Pseudoalteromonas haloplanktis

scientific article

Identification and characterization of inhibitors of cytoplasmic 5'-nucleotidase cN-II issued from virtual screening

scientific article

Identification of Noncompetitive Inhibitors of Cytosolic 5'-Nucleotidase II Using a Fragment-Based Approach

scientific article

Insights into Early Extracellular Matrix Evolution: Spongin Short Chain Collagen-Related Proteins Are Homologous to Basement Membrane Type IV Collagens and Form a Novel Family Widely Distributed in Invertebrates

article

Interactions of barley α-amylase isozymes with Ca2 + , substrates and proteinaceous inhibitors

Lead optimization and biological evaluation of fragment-based cN-II inhibitors

scientific article published on 14 February 2019

Multi-site substrate binding and interplay in barley alpha-amylase 1

scientific article

Mutations inducing an active-site aperture in Rhizobium sp. sucrose isomerase confer hydrolytic activity

scientific article

Oligosaccharide binding to barley alpha-amylase 1.

scientific article

Probing the Role of Divalent Metal Ions in a Bacterial Psychrophilic Metalloprotease: Binding Studies of an Enzyme in the Crystalline State by X-Ray Crystallography

scientific article

Probing the crucial role of Leu31 and Thr33 of the Bacillus pumilus CBS alkaline protease in substrate recognition and enzymatic depilation of animal hide

scientific article

Probing the essential catalytic residues and substrate affinity in the thermoactive Bacillus stearothermophilus US100 L-arabinose isomerase by site-directed mutagenesis.

scientific article published on 2 March 2007

Production and crystallization of the C-propeptide trimer from human procollagen III.

scientific article

Rational design of Bacillus stearothermophilus US100 L-arabinose isomerase: potential applications for D-tagatose production

scientific article published on 6 February 2009

Roles of multiple surface sites, long substrate binding clefts, and carbohydrate binding modules in the action of amylolytic enzymes on polysaccharide substrates

Specificity modulation of barley alpha-amylase through biased random mutagenesis involving a conserved tripeptide in beta --> alpha loop 7 of the catalytic (beta/alpha)(8)-barrel domain.

scientific article published on October 2001

Structural Basis for the Acceleration of Procollagen Processing by Procollagen C-Proteinase Enhancer-1

scientific article published on 2 August 2018

Structural basis of fibrillar collagen trimerization and related genetic disorders

scientific article

Structural basis of homo- and heterotrimerization of collagen I

scientific article

Structural determinants increasing flexibility confer cold adaptation in psychrophilic phosphoglycerate kinase

scientific article published on 30 May 2019

Structural determinants of product specificity of sucrose isomerases

scientific article

Structure and catalytic regulation of Plasmodium falciparum IMP specific nucleotidase

scientific article published on 26 June 2020

Structure of a full length psychrophilic cellulase from Pseudoalteromonas haloplanktis revealed by X-ray diffraction and small angle X-ray scattering

scientific article

Structuring detergents for extracting and stabilizing functional membrane proteins

scientific article

Supramolecular stabilization of acid tolerant l-arabinose isomerase from Lactobacillus sakei

scientific article published on 20 October 2011

The 'pair of sugar tongs' site on the non-catalytic domain C of barley alpha-amylase participates in substrate binding and activity

scientific article

The ABC transporter BmrA from Bacillus subtilis is a functional dimer when in a detergent-solubilized state.

scientific article published in April 2006

The acid tolerant L-arabinose isomerase from the food grade Lactobacillus sakei 23K is an attractive D-tagatose producer.

scientific article published on 14 July 2010

The acid tolerant and cold-active β-galactosidase from Lactococcus lactis strain is an attractive biocatalyst for lactose hydrolysis.

scientific article published on 21 November 2012

The acid-tolerant L-arabinose isomerase from the mesophilic Shewanella sp. ANA-3 is highly active at low temperatures

scientific article published on 10 November 2011

The attractive recombinant phytase from Bacillus licheniformis: biochemical and molecular characterization

scientific article published on 13 December 2013

The importance of an extra loop in the B-domain of an alpha-amylase from B. stearothermophilus US100.

scientific article published on 5 May 2009

The overexpression of the SAPB of Bacillus pumilus CBS and mutated sapB-L31I/T33S/N99Y alkaline proteases in Bacillus subtilis DB430: new attractive properties for the mutant enzyme.

scientific article published on 3 December 2011

The structure of barley alpha-amylase isozyme 1 reveals a novel role of domain C in substrate recognition and binding: a pair of sugar tongs

scientific article

Trehalulose synthase native and carbohydrate complexed structures provide insights into sucrose isomerization

scientific article

Two different centered monoclinic crystals of the E. coli outer-membrane protein OmpF originate from the same building block

scientific article

X-Ray Crystal Structure of the Multidomain Endoglucanase Cel9G from Clostridium cellulolyticum Complexed with Natural and Synthetic Cello-Oligosaccharides

scientific article

List of works by Nushin Aghajari

A flexible loop at the dimer interface is a part of the active site of the adjacent monomer of Escherichia coli orotate phosphoribosyltransferase

Active site coupling in Plasmodium falciparum GMP synthetase is triggered by domain rotation

An enzyme family reunion — similarities, differences and eccentricities in actions on α-glucans

Biased mutagenesis in the N-terminal region by degenerate oligonucleotide gene shuffling enhances secretory expression of barley alpha-amylase 2 in yeast

C-terminal residues regulate localization and function of the antiapoptotic protein Bfl-1.

Crystal structures of a psychrophilic metalloprotease reveal new insights into catalysis by cold-adapted proteases

Crystallization and preliminary X-ray diffraction studies on the Apo form of orotate phosphoribosyltransferase from Escherichia coli.

Diffraction anisotropy falloff in the direction of the detergent belt for two centered monoclinic crystals of OmpF

Efficient bioconversion of lactose in milk and whey: immobilization and biochemical characterization of a beta-galactosidase from the dairy Streptococcus thermophilus LMD9 strain.

Engineered glucose isomerase from Streptomyces sp. SK is resistant to Ca²⁺ inhibition and Co²⁺ independent

Engineering of the alpha-amylase from Geobacillus stearothermophilus US100 for detergent incorporation

Enhancement of the thermostability and the catalytic efficiency of Bacillus pumilus CBS protease by site-directed mutagenesis

Enhancement of the thermostability of the maltogenic amylase MAUS149 by Gly312Ala and Lys436Arg substitutions.

Expanding the Kinome World: A New Protein Kinase Family Widely Conserved in Bacteria.

Exploring the acidotolerance of beta-galactosidase from Lactobacillus delbrueckii subsp. bulgaricus: an attractive enzyme for lactose bioconversion

Expression, purification and preliminary crystallographic studies of alpha-amylase isozyme 1 from barley seeds

Expression, purification, crystallization and preliminary X-ray crystallographic studies of a psychrophilic cellulase from Pseudoalteromonas haloplanktis

Identification and characterization of inhibitors of cytoplasmic 5'-nucleotidase cN-II issued from virtual screening

Identification of Noncompetitive Inhibitors of Cytosolic 5'-Nucleotidase II Using a Fragment-Based Approach

Insights into Early Extracellular Matrix Evolution: Spongin Short Chain Collagen-Related Proteins Are Homologous to Basement Membrane Type IV Collagens and Form a Novel Family Widely Distributed in Invertebrates

Interactions of barley α-amylase isozymes with Ca2 + , substrates and proteinaceous inhibitors

Lead optimization and biological evaluation of fragment-based cN-II inhibitors

Multi-site substrate binding and interplay in barley alpha-amylase 1

Mutations inducing an active-site aperture in Rhizobium sp. sucrose isomerase confer hydrolytic activity

Oligosaccharide binding to barley alpha-amylase 1.

Probing the Role of Divalent Metal Ions in a Bacterial Psychrophilic Metalloprotease: Binding Studies of an Enzyme in the Crystalline State by X-Ray Crystallography

Probing the crucial role of Leu31 and Thr33 of the Bacillus pumilus CBS alkaline protease in substrate recognition and enzymatic depilation of animal hide

Probing the essential catalytic residues and substrate affinity in the thermoactive Bacillus stearothermophilus US100 L-arabinose isomerase by site-directed mutagenesis.

Production and crystallization of the C-propeptide trimer from human procollagen III.

Rational design of Bacillus stearothermophilus US100 L-arabinose isomerase: potential applications for D-tagatose production

Roles of multiple surface sites, long substrate binding clefts, and carbohydrate binding modules in the action of amylolytic enzymes on polysaccharide substrates

Specificity modulation of barley alpha-amylase through biased random mutagenesis involving a conserved tripeptide in beta --> alpha loop 7 of the catalytic (beta/alpha)(8)-barrel domain.

Structural Basis for the Acceleration of Procollagen Processing by Procollagen C-Proteinase Enhancer-1

Structural basis of fibrillar collagen trimerization and related genetic disorders

Structural basis of homo- and heterotrimerization of collagen I

Structural determinants increasing flexibility confer cold adaptation in psychrophilic phosphoglycerate kinase

Structural determinants of product specificity of sucrose isomerases

Structure and catalytic regulation of Plasmodium falciparum IMP specific nucleotidase

Structure of a full length psychrophilic cellulase from Pseudoalteromonas haloplanktis revealed by X-ray diffraction and small angle X-ray scattering

Structuring detergents for extracting and stabilizing functional membrane proteins

Supramolecular stabilization of acid tolerant l-arabinose isomerase from Lactobacillus sakei

The 'pair of sugar tongs' site on the non-catalytic domain C of barley alpha-amylase participates in substrate binding and activity

The ABC transporter BmrA from Bacillus subtilis is a functional dimer when in a detergent-solubilized state.

The acid tolerant L-arabinose isomerase from the food grade Lactobacillus sakei 23K is an attractive D-tagatose producer.

The acid tolerant and cold-active β-galactosidase from Lactococcus lactis strain is an attractive biocatalyst for lactose hydrolysis.

The acid-tolerant L-arabinose isomerase from the mesophilic Shewanella sp. ANA-3 is highly active at low temperatures

The attractive recombinant phytase from Bacillus licheniformis: biochemical and molecular characterization

The importance of an extra loop in the B-domain of an alpha-amylase from B. stearothermophilus US100.

The overexpression of the SAPB of Bacillus pumilus CBS and mutated sapB-L31I/T33S/N99Y alkaline proteases in Bacillus subtilis DB430: new attractive properties for the mutant enzyme.

The structure of barley alpha-amylase isozyme 1 reveals a novel role of domain C in substrate recognition and binding: a pair of sugar tongs

Trehalulose synthase native and carbohydrate complexed structures provide insights into sucrose isomerization

Two different centered monoclinic crystals of the E. coli outer-membrane protein OmpF originate from the same building block

X-Ray Crystal Structure of the Multidomain Endoglucanase Cel9G from Clostridium cellulolyticum Complexed with Natural and Synthetic Cello-Oligosaccharides