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List of works by Florence Nguyen-Khac

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TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis

scientific journal article
Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia

scientific article published on 29 July 2009
A new recurrent and specific cryptic translocation, t(5;14)(q35;q32), is associated with expression of the Hox11L2 gene in T acute lymphoblastic leukemia.

scientific article
Involvement of a human gene related to the Drosophila spen gene in the recurrent t(1;22) translocation of acute megakaryocytic leukemia

scientific article
Acquired initiating mutations in early hematopoietic cells of CLL patients

scientific article
Five members of the CEBP transcription factor family are targeted by recurrent IGH translocations in B-cell precursor acute lymphoblastic leukemia (BCP-ALL).

scientific article
Results of a randomized trial of chlorambucil versus fludarabine for patients with untreated Waldenström macroglobulinemia, marginal zone lymphoma, or lymphoplasmacytic lymphoma

scientific article
MYC-containing double minutes in hematologic malignancies: evidence in favor of the episome model and exclusion of MYC as the target gene

article
NUP98 rearrangements in hematopoietic malignancies: a study of the Groupe Francophone de Cytogénétique Hématologique.

scientific article
A new recurrent translocation t(11;14)(q24;q32) involving IGH@ and miR-125b-1 in B-cell progenitor acute lymphoblastic leukemia.

scientific article published on 20 May 2010
The t(1;12)(q21;p13) translocation of human acute myeloblastic leukemia results in a TEL-ARNT fusion.

scientific article published on June 2000
Presence of multiple recurrent mutations confers poor trial outcome of relapsed/refractory CLL.

scientific article published on 27 August 2015
Report of 34 patients with clonal chromosomal abnormalities in Philadelphia-negative cells during imatinib treatment of Philadelphia-positive chronic myeloid leukemia.

scientific article published on August 2004
Chromosomal translocations and karyotype complexity in chronic lymphocytic leukemia: a systematic reappraisal of classic cytogenetic data

scientific article
Clinical effect of stereotyped B-cell receptor immunoglobulins in chronic lymphocytic leukaemia: a retrospective multicentre study

scientific article
Antiviral therapy is associated with a better survival in patients with hepatitis C virus and B‐cell non‐Hodgkin lymphomas, ANRS HC‐13 lympho‐C study

scientific article published on November 24, 2014
Early-onset invasive aspergillosis and other fungal infections in patients treated with ibrutinib

scientific article published in February 2018
Chromosome 21 abnormalities with AML1 amplification in acute lymphoblastic leukemia

scientific article
Overexpression of CEBPA resulting from the translocation t(14;19)(q32;q13) of human precursor B acute lymphoblastic leukemia.

scientific article
A new human mast cell line expressing a functional IgE receptor converts to tumorigenic growth by KIT D816V transfection

scientific article published on 27 March 2014
Gain of the short arm of chromosome 2 (2p) is a frequent recurring chromosome aberration in untreated chronic lymphocytic leukemia (CLL) at advanced stages

article
Activating mutation in the TSLPR gene in B-cell precursor lymphoblastic leukemia

scientific article published on 12 November 2009
B-cell regulator of immunoglobulin heavy-chain transcription (Bright)/ARID3a is a direct target of the oncomir microRNA-125b in progenitor B-cells.

scientific article published on 3 April 2012
Acute myeloid leukaemia with 8p11 (MYST3) rearrangement: an integrated cytologic, cytogenetic and molecular study by the groupe francophone de cytogénétique hématologique.

scientific article published on 5 June 2008
Drug-perturbation-based stratification of blood cancer

scientific article published on 11 December 2017
Recurrence of OTT-MAL fusion in t(1;22) of infant AML-M7.

scientific article published on January 2002
t(5;14)/HOX11L2-positive T-cell acute lymphoblastic leukemia. A collaborative study of the Groupe Français de Cytogénétique Hématologique (GFCH).

scientific article published in September 2003
Description of a novel FR1 IgH PCR strategy and its comparison with three other strategies for the detection of clonality in B cell malignancies

scientific article published on 01 March 1995
Chromosomal aberrations and their prognostic value in a series of 174 untreated patients with Waldenström's macroglobulinemia

scientific article published on 12 October 2012
Hypoxia enhances human B19 erythrovirus gene expression in primary erythroid cells.

scientific article
Autologous stem cell transplantation as a first-line treatment strategy for chronic lymphocytic leukemia: a multicenter, randomized, controlled trial from the SFGM-TC and GFLLC

scientific article published on 15 March 2011
STAT3 mutations identified in human hematologic neoplasms induce myeloid malignancies in a mouse bone marrow transplantation model.

scientific article published on 19 July 2013
Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations

scientific article
Analyses of TET2 mutations in post-myeloproliferative neoplasm acute myeloid leukemias

scientific article published on 27 August 2009
The most frequent t(14;19)(q32;q13)-positive B-cell malignancy corresponds to an aggressive subgroup of atypical chronic lymphocytic leukemia

article
Minimally differentiated erythroleukaemia (AML M6 Variant'): a rare subset of AML distinct from AML M6

scientific article published on 01 August 1995
Gene expression profiling of chronic lymphocytic leukemia can discriminate cases with stable disease and mutated Ig genes from those with progressive disease and unmutated Ig genes.

scientific article published in November 2005
Haploinsufficiency for NR3C1, the gene encoding the glucocorticoid receptor, in blastic plasmacytoid dendritic cell neoplasms

scientific article published on 08 April 2016
A common alternative splicing signature is associated with SF3B1 mutations in malignancies from different cell lineages.

scientific article
CD47 agonist peptides induce programmed cell death in refractory chronic lymphocytic leukemia B cells via PLCγ1 activation: evidence from mice and humans

scientific article
Prognosis of Binet stage A chronic lymphocytic leukemia patients: the strength of routine parameters

scientific article published on 25 August 2010
Genome profiling of acute myelomonocytic leukemia: alteration of the MYB locus in MYST3-linked cases

scientific article published on 25 September 2008
Telomere dysfunction-induced foci arise with the onset of telomeric deletions and complex chromosomal aberrations in resistant chronic lymphocytic leukemia cells

article published in 2010
Spliceosome and other novel mutations in chronic lymphocytic leukemia and myeloid malignancies.

scientific article published on 09 April 2012
Antibody-dependent cellular cytotoxicity of the optimized anti-CD20 monoclonal antibody ublituximab on chronic lymphocytic leukemia cells with the 17p deletion

Different spectra of recurrent gene mutations in subsets of chronic lymphocytic leukemia harboring stereotyped B-cell receptors

scientific article published on 19 May 2016
Cytogenetic study of 75 erythroleukemias.

scientific article
Trisomy 4, a new chromosomal abnormality in Waldenström's macroglobulinemia: a study of 39 cases

scientific article published on 13 July 2006
MLL-AF1q fusion resulting from t(1;11) in acute leukemia

scientific article published on 01 February 1999
Chronic lymphocytic leukemia and prolymphocytic leukemia with MYC translocations: a subgroup with an aggressive disease course

scientific article published on 30 December 2011

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