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List of works by Florence Nguyen-Khac

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IGHV gene mutational status and LPL/ADAM29 gene expression as clinical outcome predictors in CLL patients in remission following treatment with oral fludarabine plus cyclophosphamide

scientific article
Deregulation of cyclin D2 by juxtaposition with T-cell receptor alpha/delta locus in t(12;14)(p13;q11)-positive childhood T-cell acute lymphoblastic leukemia.

scientific article
Sex chromosome loss may represent a disease-associated clonal population in chronic lymphocytic leukemia

Functional analyses of the TEL-ARNT fusion protein underscores a role for oxygen tension in hematopoietic cellular differentiation

scientific article published on 20 March 2006
The value of the monoclonal antibody, DBA44, in the diagnosis of B-lymphoid disorders

scientific article published on 01 November 1996
Abnormalities of the short arm of chromosome 12 in T cell prolymphocytic leukemia

scientific article published in June 1998
Additional trisomies amongst patients with chronic lymphocytic leukemia carrying trisomy 12: the accompanying chromosome makes a difference

scientific article published on 21 April 2016
Cytogenetic complexity in chronic lymphocytic leukemia: definitions, associations, and clinical impact

scientific article published on 02 January 2019
EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia.

scientific article published on 28 November 2016
Chromosomal translocations involving the IGH@ locus in B-cell precursor acute lymphoblastic leukemia: 29 new cases and a review of the literature

scientific article published on May 2013
Chronic lymphocytic leukemia: Time to go past genomics?

scientific article
Refinement of 1p36 alterations not involving PRDM16 in myeloid and lymphoid malignancies

scientific article
CALM-AF10 fusion gene in leukemias: simple and inversion-associated translocation (10;11).

scientific article published in October 2000
14q deletions are associated with trisomy 12,NOTCH1mutations and unmutatedIGHVgenes in chronic lymphocytic leukemia and small lymphocytic lymphoma

scientific article published on 12 April 2014
Chromosomal abnormalities in transformed Ph-negative myeloproliferative neoplasms are associated to the transformation subtype and independent of JAK2 and the TET2 mutations

scientific article published in October 2010
AML1-MTG16 fusion gene in therapy-related acute leukemia with t(16;21)(q24;q22); two new cases

article
Establishment and characterization of a new human erythroleukemic cell line, ERY-1.

scientific article
A Scoring System for the Classification of CD5- B CLL versus CD5+ B CLL and B PLL

Fluorescence in situ hybridization analysis of chromosome 1 abnormalities in hematopoietic disorders: rearrangements of DNA satellite II and new recurrent translocations

scientific article
FISH detection of chromosome 14q32/IgH translocations: evaluation in follicular lymphoma

scientific article published on 01 November 1998
Aberrant telomere structure is characteristic of resistant chronic lymphocytic leukaemia cells

scientific article published on 22 October 2009
Functional assessment of p53 in chronic lymphocytic leukemia

scientific article published on 25 February 2011
Evaluating abbreviated induction with fludarabine, cyclophosphamide, and dose-dense rituximab in elderly patients with chronic lymphocytic leukemia

scientific article published on 3 July 2015
Rituximab maintenance versus observation following abbreviated induction with chemoimmunotherapy in elderly patients with previously untreated chronic lymphocytic leukaemia (CLL 2007 SA): an open-label, randomised phase 3 study

scientific article published on 20 December 2017
High frequency of somatic mutations in the VH genes expressed in prolymphocytic leukemia.

scientific article published in November 1996
Chronic lymphocytic leukaemia genomics and the precision medicine era.

scientific article
Concomitant heterochromatinisation and down-regulation of gene expression unveils epigenetic silencing of RELB in an aggressive subset of chronic lymphocytic leukemia in males

scientific article
Obinutuzumab and ibrutinib induction therapy followed by a minimal residual disease-driven strategy in patients with chronic lymphocytic leukaemia (ICLL07 FILO): a single-arm, multicentre, phase 2 trial

scientific article published on 16 July 2019
Transcriptional activation of the cardiac homeobox gene CSX1/NKX2-5 in a B-cell chronic lymphoproliferative disorder

article
Mutational and cytogenetic analyses of 188 CLL patients with trisomy 12: A retrospective study from the French Innovative Leukemia Organization (FILO) working group

article
Specific chromosomal IG translocations have different prognoses in chronic lymphocytic leukemia

scientific article published on 15 April 2011
Trisomy 4 associated with double minute chromosomes and MYC amplification in acute myeloblastic leukemia

scientific article
Gain in the short arm of chromosome 2 (2p+) induces gene overexpression and drug resistance in chronic lymphocytic leukemia: analysis of the central role of XPO1.

scientific article
No improvement in long-term survival over time for chronic lymphocytic leukemia patients in stereotyped subsets #1 and #2 treated with chemo(immuno)therapy

scientific article published on 21 December 2017
Cyclin D3 deregulation by juxtaposition with IGH locus in a t(6;14)(p21;q32)-positive T-cell acute lymphoblastic leukemia

scientific article published on 08 August 2009
Therapy-related myelodysplastic syndrome after allogeneic BMT: successful treatment by donor lymphocyte infusions

scientific article published on 25 January 2010
Identical abnormality of the short arm of chromosome 18 in two Philadelphia-positive chronic myelocytic leukemia patients with erythroblastic transformation, resulting in duplication of BCR-ABL1 fusion.

scientific article published in October 2002
Concomitant telomere shortening, acquisition of multiple chromosomal aberrations and in vitro resistance to apoptosis in a single case of progressive CLL

article published in 2011
LHX2 deregulation by juxtaposition with the IGH locus in a pediatric case of chronic myeloid leukemia in B-cell lymphoid blast crisis.

scientific article published on 22 June 2012
Evidence of chromosomal inversion using fluorescence in situ hybridization to stretched DNA.

scientific article
Poor prognosis of chromosome 7 clonal aberrations in Philadelphia-negative metaphases and relevance of potential underlying myelodysplastic features in chronic myeloid leukemia

scientific article published on 20 December 2018
Absence of microsatellite instability in human chronic lymphocytic leukaemia B cells

Cryptic translocations involving chromosome 20 in polycythemia vera

scientific article published on 01 October 2004
Mutations des gènes impliqués dans l’épissage dans les hémopathies malignes humaines

article
A Recurrent Activating Missense Mutation in Waldenström Macroglobulinemia Affects the DNA Binding of the ETS Transcription Factor SPI1 and Enhances Proliferation

scientific article published on 24 April 2019
Anomalies chromosomiques et macroglobulinémie de Waldenström

scientific article published on 05 May 2008
Correlation of cytoplasmic Ig mu (C mu) and E2A-PBX1 fusion transcripts in t(1;19) B lineage ALL: discrepancy in C mu detection by slide immunofluorescence and flow cytometry

scientific article published on 01 March 1995
Cytogenetics in the management of chronic lymphocytic leukemia: an update by the Groupe francophone de cytogénétique hématologique (GFCH).

scientific article published on 14 September 2016
Targeting chronic lymphocytic leukemia with N-methylated thrombospondin-1-derived peptides overcomes drug resistance

scientific article published on 01 October 2019
Recommendations for cytogenomic analysis of hematologic malignancies: comments from the Francophone Group of Hematological Cytogenetics (GFCH)

scientific article published on 20 December 2019

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