List of works by Vesa P. Hytönen

(Strept)avidin as a template for ligands other than biotin: An overview

scientific article published on 20 November 2019

188. Internalization of Novel Delivery Vector TAT-Streptavidin into Human Cells

3D-Printable Bioactivated Nanocellulose-Alginate Hydrogels.

scientific article published on 9 June 2017

A Coxsackievirus B vaccine protects against virus-induced diabetes in an experimental mouse model of type 1 diabetes

scientific article published on 18 November 2017

A DNA-nanoparticle actuator enabling optical monitoring of nanoscale movements induced by an electric field

A Novel Chimeric Avidin with Increased Thermal Stability Using DNA Shuffling

scientific article

A comparative study of the effect of UV and formalin inactivation on the stability and immunogenicity of a Coxsackievirus B1 vaccine

scientific article published on 27 August 2019

A comparison of immunogenicity of norovirus GII-4 virus-like particles and P-particles

scientific article published in January 2012

A comparison of methods for purification and concentration of norovirus GII-4 capsid virus-like particles.

scientific article published on 19 August 2010

A hexavalent Coxsackievirus B vaccine is highly immunogenic and has a strong protective capacity in mice and nonhuman primates

scientific article published on 06 May 2020

A multipurpose vector system for the screening of libraries in bacteria, insect and mammalian cells and expression in vivo

scientific article

A novel rat CVB1-VP1 monoclonal antibody 3A6 detects a broad range of enteroviruses.

scientific article published on 8 January 2018

Acetaldehyde-derived modifications on cytosolic human carbonic anhydrases

scientific article published on 16 June 2011

All Subdomains of the Talin Rod Are Mechanically Vulnerable and May Contribute To Cellular Mechanosensing

scientific article

Analysis of a shortened form of human carbonic anhydrase VII expressed in vitro compared to the full-length enzyme

scientific article published on 21 May 2010

Antibody Responses against Enterovirus Proteases are Potential Markers for an Acute Infection

scientific article published on 09 January 2020

Approaching infinite affinity through engineering of peptide-protein interaction

scientific article published on 10 December 2019

Artificial Avidin-Based Receptors for a Panel of Small Molecules

scientific article

Association of neuroimmune guidance cue netrin-1 and its chemorepulsive receptor UNC5B with atherosclerotic plaque expression signatures and stability in human(s): Tampere Vascular Study (TVS).

scientific article

Avidin related protein 2 shows unique structural and functional features among the avidin protein family.

scientific article

Avidin-Conjugated Nanofibrillar Cellulose Hydrogel Functionalized with Biotinylated Fibronectin and Vitronectin Promotes 3D Culture of Fibroblasts

Bacterial avidins are a widely distributed protein family in Actinobacteria, Proteobacteria and Bacteroidetes

Beta carbonic anhydrases: novel targets for pesticides and anti-parasitic agents in agriculture and livestock husbandry

scientific article

Bifunctional avidin with covalently modifiable ligand binding site.

scientific article

Binding Properties of HABA-Type Azo Derivatives to Avidin and Avidin-Related Protein 4

scientific article published on 01 October 2006

Biochemical and structural characterisation of a protozoan beta-carbonic anhydrase from Trichomonas vaginalis

scientific article published on 01 December 2020

Biofunctional hybrid materials: bimolecular organosilane monolayers on FeCr alloys

scientific article published on 09 October 2014

Biolayer Interferometry: A Novel Method to Elucidate Protein-Protein and Protein-DNA Interactions in the Mitochondrial DNA Replisome

scientific article

Bradavidin II from Bradyrhizobium japonicum: a new avidin-like biotin-binding protein.

scientific article

Brave new (strept)avidins in biotechnology

scientific article published on 12 April 2007

Cancer associated talin point mutations disorganise cell adhesion and migration

scientific article

Carbon nanotubes as electrodes for dielectrophoresis of DNA.

scientific article published in July 2006

Cationic polymer brush-modified cellulose nanocrystals for high-affinity virus binding

scientific article

Cell Adhesion by Integrins

scientific article published on 01 October 2019

Characterization of poultry egg-white avidins and their potential as a tool in pretargeting cancer treatment.

scientific article published in May 2003

Characterization of the first beta-class carbonic anhydrase from an arthropod (Drosophila melanogaster) and phylogenetic analysis of beta-class carbonic anhydrases in invertebrates

scientific article

Chicken avidin-related protein 4/5 shows superior thermal stability when compared with avidin while retaining high affinity to biotin.

scientific article

Chicken avidin-related proteins show altered biotin-binding and physico-chemical properties as compared with avidin.

scientific article published on May 2002

Chicken genome analysis reveals novel genes encoding biotin-binding proteins related to avidin family

scientific article

Chimeric Avidin – NMR Structure and Dynamics of a 56 kDa Homotetrameric Thermostable Protein

scientific article

Chimeric avidin shows stability against harsh chemical conditions--biochemical analysis and 3D structure

scientific article

Combination of three virus-derived nanoparticles as a vaccine against enteric pathogens; enterovirus, norovirus and rotavirus

scientific article published on 01 October 2019

Comparative analysis of two paradigm bacteriophytochromes reveals opposite functionalities in two-component signaling

scientific article

Competition for Membrane Receptors: Norovirus Detachment via Lectin Attachment

scientific article published on 02 October 2019

Competitive binding assay for biotin and biotin derivatives, based on avidin and biotin-4-fluorescein

scientific article published on 20 November 2019

Connection between absorption properties and conformational changes in Deinococcus radiodurans phytochrome

scientific article published on 7 November 2014

Construction of a dual chain pseudotetrameric chicken avidin by combining two circularly permuted avidins.

scientific article

Construction of chimeric dual-chain avidin by tandem fusion of the related avidins

scientific article

Controlling quaternary structure assembly: subunit interface engineering and crystal structure of dual chain avidin

scientific article published on 6 May 2006

Core-Shell Nanorod Columnar Array Combined with Gold Nanoplate-Nanosphere Assemblies Enable Powerful In Situ SERS Detection of Bacteria.

scientific article published on 30 August 2016

Correction to "Neutralized Chimeric Avidin Binding at a Reference Biosensor Surface".

scientific article published on 28 May 2015

Correction: Saarinen, N.V.V., et al. Multiplexed High-Throughput Serological Assay for Human Enteroviruses. Microorganismis 2020, 8, 963

scientific article published on 17 September 2020

Covalent Biofunctionalization of Cellulose Acetate with Thermostable Chimeric Avidin

scientific article published on 16 June 2011

Coxsackievirus B3 VLPs purified by ion exchange chromatography elicit strong immune responses in mice.

scientific article published on 28 January 2014

Critical importance of loop conformation to avidin-enhanced hydrolysis of an active biotin ester

scientific article

Crystal structure of rhizavidin: insights into the enigmatic high-affinity interaction of an innate biotin-binding protein dimer

scientific article

Crystal structure of the FERM-folded talin head reveals the determinants for integrin binding

scientific article published on 07 December 2020

Cyanidin-3-glucoside binds to talin and modulates colon cancer cell adhesions and 3D growth

scientific article published on 09 January 2020

Cysteine-tagged chimeric avidin forms high binding capacity layers directly on gold

article published in 2012

DNA family shuffling within the chicken avidin protein family - A shortcut to more powerful protein tools

Defined-size DNA triple crossover construct for molecular electronics: modification, positioning and conductance properties.

scientific article published on 25 May 2011

Design and construction of highly stable, protease-resistant chimeric avidins.

scientific article published on 13 January 2005

Design of modular gellan gum hydrogel functionalized with avidin and biotinylated adhesive ligands for cell culture applications

scientific article published on 30 August 2019

Dual-affinity avidin molecules.

scientific article published in November 2005

Dynamic piezoelectric stimulation enhances osteogenic differentiation of human adipose stem cells

scientific article published on 11 November 2014

Efficient preparation of shuffled DNA libraries through recombination (Gateway) cloning

scientific article published on December 2014

Efficient production of active chicken avidin using a bacterial signal peptide in Escherichia coli

scientific article published on December 2004

Enhanced gene delivery by avidin-displaying baculovirus

scientific article published on February 2004

Enhancement of adhesion and promotion of osteogenic differentiation of human adipose stem cells by poled electroactive poly(vinylidene fluoride).

scientific article published on 29 May 2014

Enhancing the thermal stability of avidin. Introduction of disulfide bridges between subunit interfaces

scientific article published on 20 November 2002

Enteroviral proteases: structure, host interactions and pathogenicity.

scientific article published on 4 May 2016

Expression of Exogenous Antigens in the Mycobacterium bovis BCG Vaccine via Non-genetic Surface Decoration with the Avidin-biotin System

scientific article published on 31 January 2018

Factors Dictating the Pseudocatalytic Efficiency of Avidins

scientific article published on 03 March 2006

Food supplementation reveals constraints and adaptability of egg quality in the magpie Pica pica

article by Heli Siitari et al published 1 December 2015 in Avian Biology Research

Force-dependent ligand sensing enables αVβ3 integrin to differentiate between fibronectin and high-affinity ligands

Formalin treatment increases the stability and immunogenicity of coxsackievirus B1 VLP vaccine

scientific article published on 03 September 2019

GFP's mechanical intermediate states

scientific article

Genetically engineered avidins and streptavidins.

scientific article

Global analysis of human nonreceptor tyrosine kinase specificity using high-density peptide microarrays

scientific article

Growth of immobilized DNA by polymerase: bridging nanoelectrodes with individual dsDNA molecules.

scientific article published on 3 August 2011

High-resolution crystal structure of an avidin-related protein: insight into high-affinity biotin binding and protein stability

scientific article published on 20 April 2005

His-tagged norovirus-like particles: A versatile platform for cellular delivery and surface display.

scientific article published on 10 July 2015

Horizontal transfer of β-carbonic anhydrase genes from prokaryotes to protozoans, insects, and nematodes

scientific article published on 16 March 2016

Host Cell Calpains Can Cleave Structural Proteins from the Enterovirus Polyprotein

scientific article published on 28 November 2019

How force might activate talin's vinculin binding sites: SMD reveals a structural mechanism

scientific article

How force might activate talin's vinculin binding sites: SMD reveals a structural mechanism

scholarly article by Vesa P. Hytönen published in January 2005

Identification and characterization of a novel zebrafish (Danio rerio) pentraxin-carbonic anhydrase

scientific article published on 7 December 2017

Identification of proprotein convertase substrates using genome-wide expression correlation analysis.

scientific article

Identifying yeasts using surface enhanced Raman spectroscopy

scientific article published on 13 April 2019

Illuminating a Phytochrome Paradigm – a Light-Activated Phosphatase in Two-Component Signaling Uncovered

scientific article

Improved antifouling properties and selective biofunctionalization of stainless steel by employing heterobifunctional silane-polyethylene glycol overlayers and avidin-biotin technology

scientific article

Improved generation of recombinant baculovirus genomes in Escherichia coli

scientific article published in September 2003

Improving the Immunogenicity of the Mycobacterium bovis BCG Vaccine by Non-Genetic Bacterial Surface Decoration Using the Avidin-Biotin System

scientific article published on 30 December 2015

Induction of ligand promiscuity of αVβ3 integrin by mechanical force

scientific article published on 19 March 2020

Inhibition of the newly discovered β‑carbonic anhydrase from the protozoan pathogen Trichomonas vaginalis with inorganic anions and small molecules

scientific article published on 07 October 2020

Inhibition of the β-carbonic anhydrase from the protozoan pathogen <i>Trichomonas vaginalis</i> with sulphonamides

scientific article published on 01 December 2021

Integrin cytoplasmic domain and pITAM compete for spleen tyrosine kinase binding

scientific article

Intelectin 3 is dispensable for resistance against a mycobacterial infection in zebrafish (Danio rerio)

scientific article published in Scientific Reports

Internalization of novel non-viral vector TAT-streptavidin into human cells

scientific article

Introduction of histidine residues into avidin subunit interfaces allows pH-dependent regulation of quaternary structure and biotin binding

scientific article published on December 2003

Investigating the binding behaviour of two avidin-based testosterone binders using molecular recognition force spectroscopy

scientific article published on 01 February 2014

Involvement of β-Carbonic Anhydrase Genes in Bacterial Genomic Islands and Their Horizontal Transfer to Protists

article

Kindlin 3 (FERMT3) is associated with unstable atherosclerotic plaques, anti-inflammatory type II macrophages and upregulation of beta-2 integrins in all major arterial beds

scientific article published on 13 July 2015

Kinetics of bioconjugate nanoparticle label binding in a sandwich-type immunoassay

scientific article published on 22 November 2013

Mechanical Unfolding of Proteins-A Comparative Nonequilibrium Molecular Dynamics Study

scientific article published on 06 August 2020

Mechanical stability of talin rod controls cell migration and substrate sensing

scientific article

Mechanical unfolding reveals stable 3-helix intermediates in talin and α-catenin.

scientific article

Mechanosensing in cell-matrix adhesions - Converting tension into chemical signals

scientific article

Mechanotransduction in talin through the interaction of the R8 domain with DLC1

scientific article published on 20 July 2018

Membrane Deformation Induces Clustering of Norovirus Bound to Glycosphingolipids in a Supported Cell-Membrane Mimic.

scientific article published on 6 April 2018

Mixture of PLA-PEG and biotinylated albumin enables immobilization of avidins on electrospun fibers

scientific article published on 29 September 2016

Modern Tools for Rapid Diagnostics of Antimicrobial Resistance

scientific article published on 15 July 2020

Modification of the loops in the ligand-binding site turns avidin into a steroid-binding protein

scientific article

Modular vaccine platform based on the norovirus-like particle

scholarly article by Vili Lampinen et al published 19 January 2021 in Journal of Nanobiotechnology

Molecular engineering of avidin and hydrophobin for functional self-assembling interfaces

scientific article published on 22 May 2014

Molecular features of steroid-binding antidins and their use for assaying serum progesterone

scientific article published on 20 February 2019

Molecular tools for selective recovery and detection of lignin-derived molecules

Multiplexed High-Throughput Serological Assay for Human Enteroviruses

scientific article published on 26 June 2020

Mutation of the important Tyr-33 residue of chicken avidin: functional and structural consequences

scientific article published on January 2003

Neutralized chimeric avidin binding at a reference biosensor surface

scientific article published on 4 February 2015

New Coxsackievirus 2Apro and 3Cpro protease antibodies for virus detection and discovery of pathogenic mechanisms.

scientific article published on 6 February 2018

New PI(4,5)P2- and membrane proximal integrin-binding motifs in the talin head control beta3-integrin clustering

scientific article

Novel avidin-like protein from a root nodule symbiotic bacterium, Bradyrhizobium japonicum.

scientific article published on 28 January 2005

Optimal Relays Deployment for 802.16j Networks

scientific article

Optimized Streptavidin for Fluorescent Labeling of Biotinylated Targets

scientific article published in August 2017

Optimized production and purification of Coxsackievirus B1 vaccine and its preclinical evaluation in a mouse model.

scientific article published on June 2017

PIP2 and Talin Join Forces to Activate Integrin

article

Peptide-functionalized chitosan-DNA nanoparticles for cellular targeting

scientific article

Phosphorylated immunoreceptor tyrosine-based activation motifs and integrin cytoplasmic domains activate spleen tyrosine kinase via distinct mechanisms.

scientific article published on 12 February 2018

Polyphenols Epigallocatechin Gallate and Resveratrol, and Polyphenol-Functionalized Nanoparticles Prevent Enterovirus Infection through Clustering and Stabilization of the Viruses

scientific article

Positive association between biotin and the abundance of root-feeding nematodes

scholarly article by Aki Sinkkonen et al published June 2014 in Soil Biology and Biochemistry

Prevalence of norovirus GII-4 antibodies in Finnish children.

scientific article published in March 2011

Priming of innate antimycobacterial immunity by heat-killed Listeria monocytogenes induces sterilizing response in the adult zebrafish tuberculosis model

scientific article

Printable and flexible macroporous organosilica film with high protein adsorption capacity

Production and characterization of virus-like particles and the P domain protein of GII.4 norovirus

scientific article published on 12 May 2011

Proprotein convertase subtilisin/kexin type 7 (PCSK7) is essential for the zebrafish development and bioavailability of transforming growth factor β1a (TGFβ1a).

scientific article published on 31 October 2013

Protein conformation as a regulator of cell-matrix adhesion

scientific article published on 28 January 2014

Protein–Protein Interactions: Inhibition of Mammalian Carbonic Anhydrases I–XV by the Murine Inhibitor of Carbonic Anhydrase and Other Members of the Transferrin Family

scientific article published on 18 May 2012

Purification of norovirus-like particles (VLPs) by ion exchange chromatography

scientific article published on 14 January 2012

Quantitative pigment extraction analysis for human pluripotent stem cell derived retinal pigment epithelial cells

Rapid and sensitive detection of norovirus antibodies in human serum with a biolayer interferometry biosensor

article published in 2015

Rational Modification of Ligand-Binding Preference of Avidin by Circular Permutation and Mutagenesis

scholarly article by Juha A. E. Määttä published in May 2008

Rational design of an active avidin monomer.

scientific article published on 27 November 2002

Rational modification of ligand-binding preference of avidin by circular permutation and mutagenesis

scientific article

Regenerable Biosensors for Small-Molecule Kinetic Characterization Using SPR

scientific article published on 08 December 2020

Regenerative biosensor chips based on switchable mutants of avidin—A systematic study

Resonance assignments of the 56 kDa chimeric avidin in the biotin-bound and free forms

scientific article published on 06 March 2012

Reversible biofunctionalization of surfaces with a switchable mutant of avidin

scientific article published on 9 September 2013

Rotavirus Inner Capsid VP6 Acts as an Adjuvant in Formulations with Particulate Antigens Only

scientific article published on 07 July 2020

SERS detection of cell surface and intracellular components of microorganisms using nano-aggregated Ag substrate

scholarly article by Tibebe Lemma et al published March 2016 in Vibrational Spectroscopy

Search for KPNA7 cargo proteins in human cells reveals MVP and ZNF414 as novel regulators of cancer cell growth

scientific article published on 21 September 2016

Stable immobilisation of His-tagged proteins on BLI biosensor surface using cobalt

scholarly article by Sanna Auer et al published May 2017 in Sensors and Actuators B

Structural Insight into CVB3-VLP Non-Adjuvanted Vaccine

scientific article published on 24 August 2020

Structural and Functional Characteristics of Chimeric Avidins Physically Adsorbed onto Functionalized Polythiophene Thin Films

scientific article published on 24 July 2012

Structural and functional analysis of LIM domain-dependent recruitment of paxillin to αvβ3 integrin-positive focal adhesions

Structural and functional characteristics of xenavidin, the first frog avidin from Xenopus tropicalis

scientific article

Structural characterization of core-bradavidin in complex with biotin

scientific article

Structure and characterization of a novel chicken biotin-binding protein A (BBP-A)

scientific article

Structure of Bradavidin – C-Terminal Residues Act as Intrinsic Ligands

scientific article

StructureMapper: a high-throughput algorithm for analyzing protein sequence locations in structural data

scientific article published on 14 February 2018

Sulphonamide inhibition profile of Staphylococcus aureus β-carbonic anhydrase

scientific article published on 01 December 2020

Surface Modification of Bioactive Glass Promotes Cell Attachment and Spreading

Surface Modification of Bioresorbable Phosphate Glasses for Controlled Protein Adsorption

Surface characteristics control the attachment and functionality of (chimeric) avidin

scientific article published on 27 November 2018

Switchavidin: reversible biotin-avidin-biotin bridges with high affinity and specificity.

scientific article published on December 2014

Syndecan-4 tunes cell mechanics by activating the kindlin-integrin-RhoA pathway

scientific article published on 06 January 2020

Synergistic Expression of Histone Deacetylase 9 and Matrix Metalloproteinase 12 in M4 Macrophages in Advanced Carotid Plaques.

scientific article published on 23 March 2017

Synergistic enhancement via plasmonic nanoplate-bacteria-nanorod supercrystals for highly efficient SERS sensing of food-borne bacteria

article by Weiqiang Wang et al published February 2017 in Sensors and Actuators B

Talin and vinculin are downregulated in atherosclerotic plaque; Tampere Vascular Study

scientific article

Talin-bound NPLY motif recruits integrin-signaling adapters to regulate cell spreading and mechanosensing ⬇️

scientific article published on April 2014

Talin-mediated force transmission and talin rod domain unfolding independently regulate adhesion signaling

scientific article published on 03 April 2019

Talin2-mediated traction force drives matrix degradation and cell invasion.

scientific article published on October 2016

Tetravalent single-chain avidin: from subunits to protein domains via circularly permuted avidins

scientific article published on December 2005

The F1 loop of the talin head domain acts as a gatekeeper in integrin activation and clustering

scientific article published on 12 October 2020

The Minor Capsid Protein VP11 of Thermophilic Bacteriophage P23-77 Facilitates Virus Assembly by Using Lipid-Protein Interactions

scientific article published on 13 May 2015

The highly dynamic oligomeric structure of bradavidin II is unique among avidin proteins

scientific article

The molecular basis of talin2's high affinity toward β1-integrin

scientific article published on 3 February 2017

The talin-integrin interface under mechanical stress

scientific article

Toward Single Electron Nanoelectronics Using Self-Assembled DNA Structure

scientific article published on 12 October 2016

Translating Mechanical Force into Discrete Biochemical Signal Changes

Trapping of 27 bp–8 kbp DNA and immobilization of thiol-modified DNA using dielectrophoresis

Versatile bio-ink for covalent immobilization of chimeric avidin on sol-gel substrates.

scientific article

WINSE: WiMAX NS-2 extension

Zebavidin - An Avidin-Like Protein from Zebrafish

scientific article

pH-Dependent Deformations of the Energy Landscape of Avidin-like Proteins Investigated by Single Molecule Force Spectroscopy

scientific article published on 18 August 2014

β1D integrin splice variant stabilizes integrin dynamics and reduces integrin signaling by limiting paxillin recruitment

scientific article published on 25 April 2019

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