List of works - Marcus Ståhlman

A LC-MS-based workflow for measurement of branched fatty acid esters of hydroxy fatty acids

scientific article published on 17 March 2016

A mouse model reveals an important role for catecholamine-induced lipotoxicity in the pathogenesis of stress-induced cardiomyopathy

scientific article

ARAP2 promotes GLUT1-mediated basal glucose uptake through regulation of sphingolipid metabolism

scientific article published on 27 July 2016

ARF6 regulates neuron differentiation through glucosylceramide synthase

scientific article

AdipoR1 and AdipoR2 maintain membrane fluidity in most human cell types and independently of adiponectin

scientific article published in 2019

Altered Microbiota Contributes to Reduced Diet-Induced Obesity upon Cold Exposure

scientific article

An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans.

scientific article

ApoCIII-enriched LDL in type 2 diabetes displays altered lipid composition, increased susceptibility for sphingomyelinase, and increased binding to biglycan

scientific article published on 05 June 2009

Association of dietary and gut microbiota-related metabolites with calcific aortic stenosis

scientific article published on 18 December 2020

Associations between Dietary Patterns and Bile Acids-Results from a Cross-Sectional Study in Vegans and Omnivores

scientific article published on 23 December 2019

Atrial fibrillation in patients admitted to coronary care units in western Sweden - focus on obesity and lipotoxicity

scientific article published on 13 December 2014

Bifidobacteria or Fiber Protects against Diet-Induced Microbiota-Mediated Colonic Mucus Deterioration

scientific article published on 16 December 2017

Caenorhabditis elegans PAQR-2 and IGLR-2 Protect against Glucose Toxicity by Modulating Membrane Lipid Composition

scientific article published on 15 April 2016

Ceramides are associated with inflammatory processes in human mediastinal adipose tissue

scientific article published on 07 October 2013

Characterization of different fat depots in NAFLD using inflammation-associated proteome, lipidome and metabolome

scientific article published in Scientific Reports

Cholesteryl esters accumulate in the heart in a porcine model of ischemia and reperfusion

scientific article

Clinical dyslipidaemia is associated with changes in the lipid composition and inflammatory properties of apolipoprotein-B-containing lipoproteins from women with type 2 diabetes

scientific article published on 18 January 2012

Colesevelam attenuates cholestatic liver and bile duct injury in Mdr2-/- mice by modulating composition, signalling and excretion of faecal bile acids.

scientific article published on 10 April 2018

Correction: Caenorhabditis elegans PAQR-2 and IGLR-2 Protect against Glucose Toxicity by Modulating Membrane Lipid Composition

scientific article published on 3 June 2016

Crosstalk between Bile Acids and Gut Microbiota and Its Impact on Farnesoid X Receptor Signalling

scientific article

Cyp3a11 is not essential for the formation of murine bile acids

scientific article published on 8 March 2017

Deficiency in perilipin 5 reduces mitochondrial function and membrane depolarization in mouse hearts

scientific article published on 12 August 2017

Dietary Omega-3 Fatty Acids Increase Survival and Decrease Bacterial Load in Mice Subjected to Staphylococcus aureus-Induced Sepsis

scientific article

Dyslipidemia, but not hyperglycemia and insulin resistance, is associated with marked alterations in the HDL lipidome in type 2 diabetic subjects in the DIWA cohort: impact on small HDL particles

scientific article

Establishment of a transgenic mouse model specifically expressing human serum amyloid A in adipose tissue

scientific article

Evolutionarily conserved long-chain Acyl-CoA synthetases regulate membrane composition and fluidity

scientific article published on 26 November 2019

Genetic Disruption of Protein Kinase STK25 Ameliorates Metabolic Defects in a Diet-Induced Type 2 Diabetes Model

scientific article published on 06 April 2015

Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism

scientific article published on 5 May 2016

High-throughput analysis of sulfatides in cerebrospinal fluid using automated extraction and UPLC-MS/MS.

scientific article

High-throughput shotgun lipidomics by quadrupole time-of-flight mass spectrometry

scientific article published on 24 February 2009

Histo-blood group antigens of glycosphingolipids predict susceptibility of human intestinal enteroids to norovirus infection

scientific article published on 10 September 2020

Hypoxia Converts Human Macrophages Into Triglyceride-Loaded Foam Cells

scientific article published on 01 June 2006

Increased expression of the very low-density lipoprotein receptor mediates lipid accumulation in clear-cell renal cell carcinoma

scientific article

Induction of farnesoid X receptor signaling in germ-free mice colonized with a human microbiota

scientific article

Inhibition of intestinal bile acid absorption improves cholestatic liver and bile duct injury in a mouse model of sclerosing cholangitis

article

LDL-associated apolipoprotein J and lysozyme are associated with atherogenic properties of LDL found in type 2 diabetes and the metabolic syndrome

scientific article published on 01 March 2011

Leveraging a gain-of-function allele of Caenorhabditis elegans paqr-1 to elucidate membrane homeostasis by PAQR proteins

scientific article published on 04 August 2020

Lipid droplet-associated kinase STK25 regulates peroxisomal activity and metabolic stress response in steatotic liver

scientific article published on 19 December 2019

Liver receptor homolog-1 is a critical determinant of methyl-pool metabolism

scientific article published on 12 August 2015

Membrane fluidity is regulated by the transmembrane protein FLD-1 and its human homologs TLCD1/2

Metabolic effects of Lactobacillus reuteri DSM 17938 in people with type 2 diabetes: A randomized controlled trial.

scientific article published on 23 December 2016

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug

scientific article

Microbiome of prebiotic-treated mice reveals novel targets involved in host response during obesity

scientific article

Microbiota-induced obesity requires farnesoid X receptor

scientific article published on 6 January 2016

Network analyses identify liver-specific targets for treating liver diseases

scientific article published on 21 August 2017

NorUrsodeoxycholic acid ameliorates cholemic nephropathy in bile duct ligated mice

scientific article published on 24 February 2017

Obesity-associated microbiota contributes to mucus layer defects in genetically obese mice

scientific article published on 08 September 2020

Overexpression of protein kinase STK25 in mice exacerbates ectopic lipid accumulation, mitochondrial dysfunction and insulin resistance in skeletal muscle.

scientific article published on 16 December 2016

PAQR-2 regulates fatty acid desaturation during cold adaptation in C. elegans

scientific article

Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) affects hepatic VLDL secretion in humans and in vitro

scientific article published on 06 August 2012

Perilipin 5 is protective in the ischemic heart.

scientific article published on 16 June 2016

Personal model-assisted identification of NAD+ and glutathione metabolism as intervention target in NAFLD.

scientific article published on 02 March 2017

Pilot study with IBAT inhibitor A4250 for the treatment of cholestatic pruritus in primary biliary cholangitis.

scientific article

Plasma Imidazole Propionate Is Positively Correlated with Blood Pressure in Overweight and Obese Humans

Plin2-deficiency reduces lipophagy and results in increased lipid accumulation in the heart

Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice

Protein kinase STK25 controls lipid partitioning in hepatocytes and correlates with liver fat content in humans

scientific article published on 9 November 2015

Protein kinase STK25 regulates hepatic lipid partitioning and progression of liver steatosis and NASH.

scientific article

Proteomics and lipids of lipoproteins isolated at low salt concentrations in D2O/sucrose or in KBr.

scientific article

Rapid quantification of yeast lipid using microwave-assisted total lipid extraction and HPLC-CAD.

scientific article published on 13 May 2013

Rip2 deficiency leads to increased atherosclerosis despite decreased inflammation

scientific article published on 29 September 2011

Roux-en-Y Gastric Bypass and Vertical Banded Gastroplasty Induce Long-Term Changes on the Human Gut Microbiome Contributing to Fat Mass Regulation.

scientific article

STK25 is a critical determinant in nonalcoholic steatohepatitis

scientific article published on 15 July 2016

Serine/threonine protein kinase 25 antisense oligonucleotide treatment reverses glucose intolerance, insulin resistance, and nonalcoholic fatty liver disease in mice.

scientific article published on 20 November 2017

Sphingolipids Contribute to Human Atherosclerotic Plaque Inflammation

scientific article published on 07 April 2016

Suppression of bile acid synthesis as a tipping point in the disease course of primary sclerosing cholangitis

scientific article published in 2022

Targeting GGTase-I activates RHOA, increases macrophage reverse cholesterol transport, and reduces atherosclerosis in mice

scientific article published on 18 January 2013

Targeting acid sphingomyelinase reduces cardiac ceramide accumulation in the post-ischemic heart

scientific article

The BUME method: a new rapid and simple chloroform-free method for total lipid extraction of animal tissue

scientific article published on 10 June 2016

The BUME method: a novel automated chloroform-free 96-well total lipid extraction method for blood plasma.

scientific article published on 29 May 2012

The Gut Microbiota Modulates Energy Metabolism in the Hibernating Brown Bear Ursus arctos

scientific article published on 3 February 2016

The adiponectin receptor AdipoR2 and its Caenorhabditis elegans homolog PAQR-2 prevent membrane rigidification by exogenous saturated fatty acids

scientific article published on 8 September 2017

The impact of Roux-en-Y gastric bypass surgery on normal metabolism in a porcine model

scientific article

The importance of GLUT3 for de novo lipogenesis in hypoxia-induced lipid loading of human macrophages

scientific article

Vimentin deficiency in macrophages induces increased oxidative stress and vascular inflammation but attenuates atherosclerosis in mice

scientific article published in Scientific Reports

Zfp148 deficiency causes lung maturation defects and lethality in newborn mice that are rescued by deletion of p53 or antioxidant treatment

scientific article

p110α Hot Spot Mutations E545K and H1047R Exert Metabolic Reprogramming Independently of p110α Kinase Activity

scientific article

List of works by Marcus Ståhlman

A LC-MS-based workflow for measurement of branched fatty acid esters of hydroxy fatty acids

A mouse model reveals an important role for catecholamine-induced lipotoxicity in the pathogenesis of stress-induced cardiomyopathy

ARAP2 promotes GLUT1-mediated basal glucose uptake through regulation of sphingolipid metabolism

ARF6 regulates neuron differentiation through glucosylceramide synthase

AdipoR1 and AdipoR2 maintain membrane fluidity in most human cell types and independently of adiponectin

Altered Microbiota Contributes to Reduced Diet-Induced Obesity upon Cold Exposure

An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans.

ApoCIII-enriched LDL in type 2 diabetes displays altered lipid composition, increased susceptibility for sphingomyelinase, and increased binding to biglycan

Association of dietary and gut microbiota-related metabolites with calcific aortic stenosis

Associations between Dietary Patterns and Bile Acids-Results from a Cross-Sectional Study in Vegans and Omnivores

Atrial fibrillation in patients admitted to coronary care units in western Sweden - focus on obesity and lipotoxicity

Bifidobacteria or Fiber Protects against Diet-Induced Microbiota-Mediated Colonic Mucus Deterioration

Caenorhabditis elegans PAQR-2 and IGLR-2 Protect against Glucose Toxicity by Modulating Membrane Lipid Composition

Ceramides are associated with inflammatory processes in human mediastinal adipose tissue

Characterization of different fat depots in NAFLD using inflammation-associated proteome, lipidome and metabolome

Cholesteryl esters accumulate in the heart in a porcine model of ischemia and reperfusion

Clinical dyslipidaemia is associated with changes in the lipid composition and inflammatory properties of apolipoprotein-B-containing lipoproteins from women with type 2 diabetes

Colesevelam attenuates cholestatic liver and bile duct injury in Mdr2-/- mice by modulating composition, signalling and excretion of faecal bile acids.

Correction: Caenorhabditis elegans PAQR-2 and IGLR-2 Protect against Glucose Toxicity by Modulating Membrane Lipid Composition

Crosstalk between Bile Acids and Gut Microbiota and Its Impact on Farnesoid X Receptor Signalling

Cyp3a11 is not essential for the formation of murine bile acids

Deficiency in perilipin 5 reduces mitochondrial function and membrane depolarization in mouse hearts

Dietary Omega-3 Fatty Acids Increase Survival and Decrease Bacterial Load in Mice Subjected to Staphylococcus aureus-Induced Sepsis

Dyslipidemia, but not hyperglycemia and insulin resistance, is associated with marked alterations in the HDL lipidome in type 2 diabetic subjects in the DIWA cohort: impact on small HDL particles

Establishment of a transgenic mouse model specifically expressing human serum amyloid A in adipose tissue

Evolutionarily conserved long-chain Acyl-CoA synthetases regulate membrane composition and fluidity

Genetic Disruption of Protein Kinase STK25 Ameliorates Metabolic Defects in a Diet-Induced Type 2 Diabetes Model

Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism

High-throughput analysis of sulfatides in cerebrospinal fluid using automated extraction and UPLC-MS/MS.

High-throughput shotgun lipidomics by quadrupole time-of-flight mass spectrometry

Histo-blood group antigens of glycosphingolipids predict susceptibility of human intestinal enteroids to norovirus infection

Hypoxia Converts Human Macrophages Into Triglyceride-Loaded Foam Cells

Increased expression of the very low-density lipoprotein receptor mediates lipid accumulation in clear-cell renal cell carcinoma

Induction of farnesoid X receptor signaling in germ-free mice colonized with a human microbiota

Inhibition of intestinal bile acid absorption improves cholestatic liver and bile duct injury in a mouse model of sclerosing cholangitis

LDL-associated apolipoprotein J and lysozyme are associated with atherogenic properties of LDL found in type 2 diabetes and the metabolic syndrome

Leveraging a gain-of-function allele of Caenorhabditis elegans paqr-1 to elucidate membrane homeostasis by PAQR proteins

Lipid droplet-associated kinase STK25 regulates peroxisomal activity and metabolic stress response in steatotic liver

Liver receptor homolog-1 is a critical determinant of methyl-pool metabolism

Membrane fluidity is regulated by the transmembrane protein FLD-1 and its human homologs TLCD1/2

Metabolic effects of Lactobacillus reuteri DSM 17938 in people with type 2 diabetes: A randomized controlled trial.

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug

Microbiome of prebiotic-treated mice reveals novel targets involved in host response during obesity

Microbiota-induced obesity requires farnesoid X receptor

Network analyses identify liver-specific targets for treating liver diseases

NorUrsodeoxycholic acid ameliorates cholemic nephropathy in bile duct ligated mice

Obesity-associated microbiota contributes to mucus layer defects in genetically obese mice

Overexpression of protein kinase STK25 in mice exacerbates ectopic lipid accumulation, mitochondrial dysfunction and insulin resistance in skeletal muscle.

PAQR-2 regulates fatty acid desaturation during cold adaptation in C. elegans

Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) affects hepatic VLDL secretion in humans and in vitro

Perilipin 5 is protective in the ischemic heart.

Personal model-assisted identification of NAD+ and glutathione metabolism as intervention target in NAFLD.

Pilot study with IBAT inhibitor A4250 for the treatment of cholestatic pruritus in primary biliary cholangitis.

Plasma Imidazole Propionate Is Positively Correlated with Blood Pressure in Overweight and Obese Humans

Plin2-deficiency reduces lipophagy and results in increased lipid accumulation in the heart

Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice

Protein kinase STK25 controls lipid partitioning in hepatocytes and correlates with liver fat content in humans

Protein kinase STK25 regulates hepatic lipid partitioning and progression of liver steatosis and NASH.

Proteomics and lipids of lipoproteins isolated at low salt concentrations in D2O/sucrose or in KBr.

Rapid quantification of yeast lipid using microwave-assisted total lipid extraction and HPLC-CAD.

Rip2 deficiency leads to increased atherosclerosis despite decreased inflammation

Roux-en-Y Gastric Bypass and Vertical Banded Gastroplasty Induce Long-Term Changes on the Human Gut Microbiome Contributing to Fat Mass Regulation.

STK25 is a critical determinant in nonalcoholic steatohepatitis

Serine/threonine protein kinase 25 antisense oligonucleotide treatment reverses glucose intolerance, insulin resistance, and nonalcoholic fatty liver disease in mice.

Sphingolipids Contribute to Human Atherosclerotic Plaque Inflammation

Suppression of bile acid synthesis as a tipping point in the disease course of primary sclerosing cholangitis

Targeting GGTase-I activates RHOA, increases macrophage reverse cholesterol transport, and reduces atherosclerosis in mice

Targeting acid sphingomyelinase reduces cardiac ceramide accumulation in the post-ischemic heart

The BUME method: a new rapid and simple chloroform-free method for total lipid extraction of animal tissue

The BUME method: a novel automated chloroform-free 96-well total lipid extraction method for blood plasma.

The Gut Microbiota Modulates Energy Metabolism in the Hibernating Brown Bear Ursus arctos

The adiponectin receptor AdipoR2 and its Caenorhabditis elegans homolog PAQR-2 prevent membrane rigidification by exogenous saturated fatty acids

The impact of Roux-en-Y gastric bypass surgery on normal metabolism in a porcine model

The importance of GLUT3 for de novo lipogenesis in hypoxia-induced lipid loading of human macrophages

Vimentin deficiency in macrophages induces increased oxidative stress and vascular inflammation but attenuates atherosclerosis in mice

Zfp148 deficiency causes lung maturation defects and lethality in newborn mice that are rescued by deletion of p53 or antioxidant treatment

p110α Hot Spot Mutations E545K and H1047R Exert Metabolic Reprogramming Independently of p110α Kinase Activity