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List of works by Bruno Pagano

Application of “magnetic tongue” to the sensory evaluation of extra virgin olive oil

scholarly article by Ilaria Lauri et al published October 2013 in Food Chemistry

Applications of isothermal titration calorimetry in biophysical studies of G-quadruplexes

scientific article published on June 2009

Assessing the influence of pH and cationic strength on i-motif DNA structure

scientific article published on 16 September 2019

Binding of Harmine Derivatives to DNA: A Spectroscopic Investigation.

scientific article published on 27 October 2017

Bio-Inspired Dual-Selective BCL-2/c-MYC G-Quadruplex Binders: Design, Synthesis, and Anticancer Activity of Drug-like Imidazo[2,1-i]purine Derivatives

scientific article published on 10 July 2019

Bis-indole derivatives with antitumor activity turn out to be specific ligands of human telomeric G-quadruplex

scientific article

Characterisation of the Dynamic Interactions between Complex N-Glycans and Human CD22

scientific article published on 17 October 2019

Characterization of monovarietal extra virgin olive oils from the province of Béjaïa (Algeria)

scholarly article by Firdousse Laincer et al published November 2016 in Food Research International

Controlled Pore Glass-based oligonucleotide affinity support: towards High Throughput Screening methods for the identification of conformation-selective G-quadruplex ligands

scientific article published on 03 May 2018

Cross-talk between prion protein and quadruplex-forming nucleic acids: a dynamic complex formation

scientific article published on 27 October 2012

Cyclodextrin-assisted assembly of PEGylated polyester nanoparticles decorated with folate

scientific article published on 22 January 2016

Design, synthesis, biophysical and biological studies of trisubstituted naphthalimides as G-quadruplex ligands

scientific article published on September 2011

Differential scanning calorimetry to investigate G-quadruplexes structural stability

scientific article published on 14 March 2013

Discovery of the first dual G-triplex/G-quadruplex stabilizing compound: a new opportunity in the targeting of G-rich DNA structures?

scientific article

Energetics of Ligand Binding to G-Quadruplexes ⬇️

scientific article published on January 1, 2013

Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis

scientific article published on 11 December 2013

Exploring the chemical space of G-quadruplex binders: discovery of a novel chemotype targeting the human telomeric sequence

scientific article published on 27 November 2013

Fluorescence enhancement upon G-quadruplex folding: synthesis, structure, and biophysical characterization of a dansyl/cyclodextrin-tagged thrombin binding aptamer.

scientific article published on 25 October 2013

Folding intermediate states of the parallel human telomeric G-quadruplex DNA explored using Well-Tempered Metadynamics

scientific article published on 21 February 2020

G-Quadruplex Binders Induce Immunogenic Cell Death Markers in Aggressive Breast Cancer Cells

scientific article published on 15 November 2019

G-Quadruplex on Oligo Affinity Support (G4-OAS): An Easy Affinity Chromatography-Based Assay for the Screening of G-Quadruplex Ligands

scientific article published on 14 April 2014

HMGB1 binds to the KRAS promoter G-quadruplex: a new player in oncogene transcriptional regulation?

scientific article published on 01 August 2018

How are thermodynamically stable G-quadruplex–duplex hybrids?

Identification of an acetal derivative of the piperonyl methyl ketone in tablets seized for suspected drug trafficking

Identification of novel interactors of human telomeric G-quadruplex DNA

Impact of phytosterols on liver and distal colon metabolome in experimental murine colitis model: an explorative study

scientific article published on 01 December 2019

In silico phosphorylation of the autoinhibited form of p47(phox): insights into the mechanism of activation

scientific article

Insights into telomeric G-quadruplex DNA recognition by HMGB1 protein

scientific article published on 01 October 2019

Intragenic G-quadruplex structure formed in the human CD133 and its biological and translational relevance

scientific article published on 27 October 2015

Lead Discovery of Dual G-Quadruplex Stabilizers and Poly(ADP-ribose) Polymerases (PARPs) Inhibitors: A New Avenue in Anticancer Treatment.

scientific article

Ligand binding to G-quadruplex DNA: new insights from ultraviolet resonance Raman spectroscopy

scientific article published on 04 April 2020

Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations

scientific article published on 23 February 2017

Looking for efficient G-quadruplex ligands: evidence for selective stabilizing properties and telomere damage by drug-like molecules

scientific article

Molecular dynamics study of the conformational stability of esterase 2 from Alicyclobacillus acidocaldarius.

scientific article published on 10 September 2011

Monohydrazone Based G-Quadruplex Selective Ligands Induce DNA Damage and Genome Instability in Human Cancer Cells

scientific article published on 18 March 2020

Mutants of the tumour suppressor p53 L1 loop as second-site suppressors for restoring DNA binding to oncogenic p53 mutations: structural and biochemical insights

article

Native Ion Mobility Mass Spectrometry: When Gas-Phase Ion Structures Depend on the Electrospray Charging Process

scientific article published on 28 March 2019

Noncanonical DNA secondary structures as drug targets: the prospect of the i-motif

scientific article published on 24 June 2014

Probing the interaction of distamycin A with S100β: the “unexpected” ability of S100β to bind to DNA-binding ligands

scholarly article by Linda Cerofolini published in February 2015

Relative Stereochemistry of a Diterpene from Salvia cinnabarina

Screening of DNA G-quadruplex stabilizing ligands by nano differential scanning fluorimetry

scientific article published on 01 November 2019

Selective Binding of Distamycin A Derivative to G-Quadruplex Structure [d(TGGGGT)](4).

scientific article

Shading the TRF2 Recruiting Function: A New Horizon in Drug Development

article

Shedding Light on the Interaction between TMPyP4 and Human Telomeric Quadruplexes

article by Luigi Martino et al published 5 November 2009 in Journal of Physical Chemistry

Shooting for Selective Druglike G-Quadruplex Binders: Evidence for Telomeric DNA Damage and Tumor Cell Death

article

Stability and Cations Coordination of DNA and RNA 14-Mer G-Quadruplexes: A Multiscale Computational Approach

Stability and binding properties of a modified thrombin binding aptamer

scientific article published on 21 September 2007

State-of-the-art methodologies for the discovery and characterization of DNA G-quadruplex binders.

scientific article published on January 2012

Structural and conformational investigation of nemorosone: A combined X-ray and quantum mechanical study

scientific article published in September 2008

Structural and conformational requisites in DNA quadruplex groove binding: another piece to the puzzle

scientific article

Structural and thermodynamic studies of the interaction of distamycin A with the parallel quadruplex structure [d(TGGGGT)]4

scientific article

Structural insight into the h TERT intron 6 sequence d(GGGGTGAAAGGGG) from 1H-NMR study

scholarly article by Ada Virno et al published 26 November 2007 in Nucleosides, Nucleotides & Nucleic Acids

Structure and stability insights into tumour suppressor p53 evolutionary related proteins

scientific article

Structure of a Stable G-Hairpin.

scientific article published on 20 February 2017

Studying the effect of crowding and dehydration on DNA G-quadruplexes

scientific article

Tandem application of ligand-based virtual screening and G4-OAS assay to identify novel G-quadruplex-targeting chemotypes.

scientific article

Targeting DNA quadruplexes with distamycin A and its derivatives: an ITC and NMR study

scientific article published on 28 March 2008

Targeting G-quadruplex structure in the human c-Kit promoter with short PNA sequences

scientific article

Targeting multiple G-quadruplex-forming DNA sequences: Design, biophysical and biological evaluations of indolo-naphthyridine scaffold derivatives

scientific article published on 16 August 2019

Targeting the BCL2 Gene Promoter G-Quadruplex with a New Class of Furopyridazinone-Based Molecules

scientific article published on 18 January 2018

The G-Triplex DNA

The triazatruxene derivative azatrux binds to the parallel form of the human telomeric G-quadruplex under molecular crowding conditions: Biophysical and molecular modeling studies

scientific article published in 2011

Thermodynamic analysis of quadruplex DNA-drug interaction

scientific article published in January 2007

Thermodynamics and kinetics of PNA-DNA quadruplex-forming chimeras

scientific article

Toward G-Quadruplex-Based Anticancer Agents: Biophysical and Biological Studies of Novel AS1411 Derivatives

scientific article published on 21 October 2020

Toward the Development of Specific G-Quadruplex Binders: Synthesis, Biophysical, and Biological Studies of New Hydrazone Derivatives

article

Use of NMR in profiling of cocaine seizures

scientific article published on 17 May 2013

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