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List of works by Andrew Pierce

A hierarchical statistical modeling approach to analyze proteomic isobaric tag for relative and absolute quantitation data

scientific article

A novel mechanism for BCR-ABL action: stimulated secretion of CCN3 is involved in growth and differentiation regulation

scientific article (publication date: September 2006)

A pathway from leukemogenic oncogenes and stem cell chemokines to RNA processing via THOC5.

scientific article

A specific PTPRC/CD45 phosphorylation event governed by stem cell chemokine CXCL12 regulates primitive hematopoietic cell motility

scientific article published on September 2013

AXL Inhibition Extinguishes Primitive JAK2 Mutated Myeloproliferative Neoplasm Progenitor Cells

scientific article published on 04 June 2019

Acquired cross-linker resistance associated with a novel spliced BRCA2 protein variant for molecular phenotyping of BRCA2 disruption.

scientific article published on 15 June 2017

Activation of granulocyte-macrophage colony-stimulating factor and interleukin-3 receptor subunits in a multipotential hematopoietic progenitor cell line leads to differential effects on development.

scientific article published on September 1999

An activated protein kinase C alpha gives a differentiation signal for hematopoietic progenitor cells and mimicks macrophage colony-stimulating factor-stimulated signaling events

scientific journal article

Antibody-based detection of protein phosphorylation status to track the efficacy of novel therapies using nanogram protein quantities from stem cells and cell lines

scientific article

Assessment of downstream effectors of BCR/ABL protein tyrosine kinase using combined proteomic approaches

scientific article published on September 2010

BCR-ABL alters the proliferation and differentiation response of multipotent hematopoietic cells to stem cell factor

scientific article published on May 2002

BCR/ABL modulates protein phosphorylation associated with the etoposide-induced DNA damage response

scientific article

Bcr-Abl protein tyrosine kinase activity induces a loss of p53 protein that mediates a delay in myeloid differentiation

scientific article

Bcr-Abl-mediated molecular mechanism for apoptotic suppression in multipotent haemopoietic cells: a role for PKCbetaII.

scientific article published on February 2004

Chronic myeloid leukemia CD34+ cells have elevated levels of phosphatidylinositol 3,4,5 trisphosphate (PtdIns(3,4,5)P3) and lack a PtdIns(3,4,5)P3 response to cytokines and chemotactic factors; effects reversed by imatinib.

scientific article published in October 2005

Combination of curaxin and tyrosine kinase inhibitors display enhanced killing of primitive Chronic Myeloid Leukaemia cells

scientific article published on 31 March 2022

Comparative proteomics of primitive hematopoietic cell populations reveals differences in expression of proteins regulating motility

scientific article published on 05 February 2004

Correction: Identification of Nuclear Protein Targets for Six Leukemogenic Tyrosine Kinases Governed by Post-Translational Regulation.

scientific article published on 27 June 2013

Development of a selected reaction monitoring mass spectrometry-based assay to detect asparaginyl endopeptidase activity in biological fluids

scientific article published on 23 September 2016

Differential effect of leukaemogenic tyrosine kinases on cell motility is governed by subcellular localisation.

scientific article published on May 2006

Dual targeting of p53 and c-MYC selectively eliminates leukaemic stem cells

scientific article

ERK and AKT phosphorylation status in lung cancer and emphysema using nanocapillary isoelectric focusing

scientific article published on 17 February 2016

EVI1 carboxy-terminal phosphorylation is ATM-mediated and sustains transcriptional modulation and self-renewal via enhanced CtBP1 association

scientific article published on 01 September 2018

Ectopic interleukin-5 receptor expression promotes proliferation without development in a multipotent hematopoietic cell line

scientific article published on March 1998

Eight-channel iTRAQ enables comparison of the activity of six leukemogenic tyrosine kinases

scientific article published on 21 October 2007

Generation of a conditionally immortalized myeloid progenitor cell line requiring the presence of both interleukin-3 and stem cell factor to survive and proliferate

scientific article published on September 2003

Global effects of BCR/ABL and TEL/PDGFRbeta expression on the proteome and phosphoproteome: identification of the Rho pathway as a target of BCR/ABL.

scientific article

Haemopoietic growth factors and leukaemogenesis

scientific article published on May 1997

Hypoxia-induced down-regulation of BRCA1 expression by E2Fs.

scientific article

Identification of nuclear protein targets for six leukemogenic tyrosine kinases governed by post-translational regulation

scientific article

Identification of primary structural features that define the differential actions of IL-3 and GM-CSF receptors

scientific article published on November 2002

Influence of chemotherapeutants and cytokines on growth and transgene expression of bone marrow cells from MT/p210(bcr-abl) transgenic mice

scientific article published on 01 January 1999

Lysophospholipids synergistically promote primitive hematopoietic cell chemotaxis via a mechanism involving Vav 1

scientific article published on 26 June 2003

MPL W515L expression induces TGFβ secretion and leads to an increase in chemokinesis via phosphorylation of THOC5.

scientific article published on 23 February 2016

Oncogenic MYC amplifies mitotic perturbations

scientific article published on 28 August 2019

Phosphorylation of the leukemic oncoprotein EVI1 on serine 196 modulates DNA binding, transcriptional repression and transforming ability

scientific article published in 2013

Proteomic Analysis of an Induced Pluripotent Stem Cell Model Reveals Strategies to Treat Juvenile Myelomonocytic Leukemia

scientific article published on 12 November 2019

Proteomic analysis of JAK2V617F-induced changes identifies potential new combinatorial therapeutic approaches

scientific article published on 23 May 2017

Proteomic analysis reveals a novel mechanism induced by the leukemic oncogene Tel/PDGFRβ in stem cells: activation of the interferon response pathways

scientific article published on 26 August 2010

Quantitative proteomic analysis using isobaric protein tags enables rapid comparison of changes in transcript and protein levels in transformed cells

scientific article

Quantitative proteomics reveals posttranslational control as a regulatory factor in primary hematopoietic stem cells

scientific article published on 28 February 2006

Role of the C-terminal actin binding domain in BCR/ABL-mediated survival and drug resistance.

scientific article published on March 2006

THOC5 controls 3'end-processing of immediate early genes via interaction with polyadenylation specific factor 100 (CPSF100).

scientific article

THOC5 couples M-CSF receptor signaling to transcription factor expression

scientific article

THOC5 spliceosome protein: a target for leukaemogenic tyrosine kinases that affects inositol lipid turnover

scientific article

The antiproliferative activity of kinase inhibitors in chronic myeloid leukemia cells is mediated by FOXO transcription factors

scientific article

The effect of Bcr-Abl protein tyrosine kinase on maturation and proliferation of primitive haematopoietic cells

scientific article published on October 2000

The specific enhancement of interferon alpha induced growth inhibition by BCR/ABL only occurs in multipotent cells

scientific article published on January 2001

Transforming growth factor-beta 1 induces apoptosis independently of p53 and selectively reduces expression of Bcl-2 in multipotent hematopoietic cells

scientific article published on December 2000

Transglutaminase 2 expression in acute myeloid leukemia: association with adhesion molecule expression and leukemic blast motility

scientific article published on 6 June 2013

p210 Bcr-Abl expression in a primitive multipotent haematopoietic cell line models the development of chronic myeloid leukaemia.

scientific article published on August 1998

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