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Chronic myeloid leukemia CD34+ cells have elevated levels of phosphatidylinositol 3,4,5 trisphosphate (PtdIns(3,4,5)P3) and lack a PtdIns(3,4,5)P3 response to cytokines and chemotactic factors; effects reversed by imatinib.

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Description scientific article published in October 2005
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author: Elaine Spooncer  Anthony D Whetton  Alexander Gray  Andrew Pierce 

Publication date October 1, 2005
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