Advanced search

Authors whose works are in public domain in at least one jurisdiction

List of works by Patrício Soares-da-Silva

1-50 of 337 results

View this query on the Wikidata Query Service
Pharmacokinetic and safety profile of trans-resveratrol in a rising multiple-dose study in healthy volunteers

scientific article published in May 2009
Efficacy and safety of eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures: a randomized, double-blind, placebo-controlled, parallel-group phase III study

scientific article published on 21 February 2009
Anticonvulsant and sodium channel-blocking properties of novel 10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide derivatives

scientific article published on 01 July 1999
Impaired synthesis or cellular storage of norepinephrine, dopamine, and 5-hydroxytryptamine in human inflammatory bowel disease.

scientific article published on January 2002
Efficacy and safety of 800 and 1200 mg eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures

scientific article published in November 2009
Eslicarbazepine acetate as adjunctive therapy in adult patients with partial epilepsy

scientific article published on 17 March 2010
Mice lacking D5 dopamine receptors have increased sympathetic tone and are hypertensive

scientific article (publication date: 15 December 2002)
Mechanisms of action of carbamazepine and its derivatives, oxcarbazepine, BIA 2-093, and BIA 2-024.

scientific article
Dopamine and G protein-coupled receptor kinase 4 in the kidney: role in blood pressure regulation

scientific article
Dopamine 5 receptor mediates Ang II type 1 receptor degradation via a ubiquitin-proteasome pathway in mice and human cells.

scientific article
Eslicarbazepine acetate (BIA 2-093).

scientific article
Decrease of adenosine A1 receptor density and of adenosine neuromodulation in the hippocampus of kindled rats

scientific article published in August 2003
Catechol-O-methyltransferase and its inhibitors in Parkinson's disease

scientific article
Pharmacokinetics and drug interactions of eslicarbazepine acetate.

scientific article
Pharmacokinetics of trans-resveratrol following repeated administration in healthy elderly and young subjects

scientific article published in October 2009
Pharmacokinetics of eslicarbazepine acetate in patients with moderate hepatic impairment

scientific article published on 21 December 2007
Interaction of the novel anticonvulsant, BIA 2-093, with voltage-gated sodium channels: comparison with carbamazepine

scientific article
Single-dose and steady-state pharmacokinetics of eslicarbazepine acetate (BIA 2-093) in healthy elderly and young subjects

scientific article published in September 2005
Long-term efficacy and safety of eslicarbazepine acetate: results of a 1-year open-label extension study in partial-onset seizures in adults with epilepsy

scientific article published on October 2010
Eslicarbazepine Acetate: A Double-blind, Add-on, Placebo-controlled Exploratory Trial in Adult Patients with Partial-onset Seizures

scientific article published on 21 February 2007
Oxidative and non-oxidative mechanisms of neuronal cell death and apoptosis by L-3,4-dihydroxyphenylalanine (L-DOPA) and dopamine.

scientific article published in December 2002
Metabolism of two new antiepileptic drugs and their principal metabolites S(+)- and R(-)-10,11-dihydro-10-hydroxy carbamazepine

scientific article published in May 2001
Long-term safety and efficacy of eslicarbazepine acetate as adjunctive therapy in the treatment of partial-onset seizures in adults with epilepsy: results of a 1-year open-label extension study

scientific article published on 4 August 2012
Long-term effect of convulsive behavior on the density of adenosine A1 and A 2A receptors in the rat cerebral cortex

scientific article published in January 2005
Angiotensin-II type 1 receptor-mediated hypertension in D4 dopamine receptor-deficient mice

scientific article published on 27 December 2005
Eslicarbazepine acetate as adjunctive therapy in patients with uncontrolled partial-onset seizures: Results of a phase III, double-blind, randomized, placebo-controlled trial

scientific article
Eslicarbazepine and the enhancement of slow inactivation of voltage-gated sodium channels: a comparison with carbamazepine, oxcarbazepine and lacosamide.

scientific article published on 19 September 2014
Carbamazepine inhibits L-type Ca2+ channels in cultured rat hippocampal neurons stimulated with glutamate receptor agonists.

scientific article published in September 1999
Steady-state plasma and cerebrospinal fluid pharmacokinetics and tolerability of eslicarbazepine acetate and oxcarbazepine in healthy volunteers

scientific article
Pharmacokinetics, efficacy, and tolerability of eslicarbazepine acetate in children and adolescents with epilepsy

scientific article published on 28 May 2008
Discovery of a long-acting, peripherally selective inhibitor of catechol-O-methyltransferase.

scientific article published in April 2010
Aging increases oxidative stress and renal expression of oxidant and antioxidant enzymes that are associated with an increased trend in systolic blood pressure.

scientific article published on July 2009
Targeting pharmacoresistant epilepsy and epileptogenesis with a dual-purpose antiepileptic drug

scientific article published on 2 December 2014
Dopamine 5 receptor mediates Ang II type 1 receptor degradation via a ubiquitin-proteasome pathway in mice and human cells

Why healthy subjects volunteer for phase I studies and how they perceive their participation?

scientific article published on 20 September 2007
Safety, tolerability, and pharmacokinetic profile of BIA 2-093, a novel putative antiepileptic, in a rising multiple-dose study in young healthy humans

scientific article
Kinetics and crystal structure of catechol-o-methyltransferase complex with co-substrate and a novel inhibitor with potential therapeutic application

scientific article
Role of cAMP-PKA-PLC signaling cascade on dopamine-induced PKC-mediated inhibition of renal Na(+)-K(+)-ATPase activity.

scientific article published in June 2002
Effect of gender on the pharmacokinetics of eslicarbazepine acetate (BIA 2-093), a new voltage-gated sodium channel blocker

scientific article published in July 2007
Pharmacokinetics, pharmacodynamics and tolerability of opicapone, a novel catechol-O-methyltransferase inhibitor, in healthy subjects: prediction of slow enzyme-inhibitor complex dissociation of a short-living and very long-acting inhibitor.

scientific article published in February 2013
Neurotoxicity induced by antiepileptic drugs in cultured hippocampal neurons: a comparative study between carbamazepine, oxcarbazepine, and two new putative antiepileptic drugs, BIA 2-024 and BIA 2-093.

scientific article published in December 2004
Effects of tolcapone upon soluble and membrane-bound brain and liver catechol-O-methyltransferase

scientific article published on 01 March 1999
Defective D1-like receptor-mediated inhibition of the Cl-/HCO3- exchanger in immortalized SHR proximal tubular epithelial cells

scientific article published on 17 February 2004
A kinetic study of the rate of formation of dopamine, 3,4-dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA) in the brain of the rat: implications for the origin of DOPAC.

scientific article published in October 1990
Opicapone as an adjunct to levodopa in patients with Parkinson's disease and end-of-dose motor fluctuations: a randomised, double-blind, controlled trial

scientific article published on 22 December 2015
Pharmacokinetics of eslicarbazepine acetate at steady-state in adults with partial-onset seizures

article
Computation of the binding affinities of catechol-O-methyltransferase inhibitors: multisubstate relative free energy calculations.

scientific article published on 25 January 2012
Renal amino acid transport systems and essential hypertension

scientific article published on April 24, 2013
The novel anticonvulsant BIA 2-093 inhibits transmitter release during opening of voltage-gated sodium channels: a comparison with carbamazepine and oxcarbazepine

scientific article published in April 2002
Safety, tolerability and pharmacokinetic profile of BIA 2-093, a novel putative antiepileptic agent, during first administration to humans

scientific article published in January 2003

Paulina is supported by:

About Paulina

Help