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List of works by Jukka Rantanen

A New Approach to Dissolution Testing by UV Imaging and Finite Element Simulations

scientific article published on 11 January 2013

A case study of real-time monitoring of solid-state phase transformations in acoustically levitated particles using near infrared and Raman spectroscopy

scientific article

A high throughput platform for understanding the influence of excipients on physical and chemical stability

scientific article published on 24 August 2012

A novel image analysis methodology for online monitoring of nucleation and crystal growth during solid state phase transformations

scientific article published on 04 May 2012

A novel method of producing a microcrystalline beta-sitosterol suspension in oil.

scientific article

A step toward development of printable dosage forms for poorly soluble drugs

scientific article published on 31 July 2013

Amino acids as stabilizers for spray-dried simvastatin powder for inhalation

scientific article published on 31 October 2019

Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging

scientific article

Analytical aspects of printed oral dosage forms

scientific article published on 11 October 2018

Analytical method development for powder characterization: Visualization of the critical drug loading affecting the processability of a formulation for direct compression

scientific article published on 09 June 2016

Anhydrate to hydrate solid-state transformations of carbamazepine and nitrofurantoin in biorelevant media studied in situ using time-resolved synchrotron X-ray diffraction

scientific article published on 13 January 2016

Anti-tuberculosis drug combination for controlled oral delivery using 3D printed compartmental dosage forms: From drug product design to in vivo testing

scientific article published on 6 October 2017

Assessment of crystalline disorder in cryo-milled samples of indomethacin using atomic pair-wise distribution functions.

scientific article

Atomic pairwise distribution function analysis of the amorphous phase prepared by different manufacturing routes.

scientific article published on 31 January 2012

Behaviour of HPMC compacts investigated using UV-imaging.

scientific article published on 3 March 2012

Budesonide nanocrystal-loaded hyaluronic acid microparticles for inhalation: In vitro and in vivo evaluation.

scientific article

Building quality into a coating process

scientific article published on 01 January 2010

Building the quality into pellet manufacturing environment--feasibility study and validation of an in-line quantitative near infrared (NIR) method

scientific article

Cardiac vagal tone, a non-invasive measure of parasympathetic tone, is a clinically relevant tool in Type 1 diabetes mellitus

scientific article

Characterisation of blends of paracetamol and citric acid

scientific article published on 01 March 2007

Characterisation of pore structures of pharmaceutical tablets: A review.

scientific article published on 13 January 2018

Characterization of polymorphic solid-state changes using variable temperature X-ray powder diffraction

scientific article published in September 2005

Characterization of spray dried bioadhesive metformin microparticles for oromucosal administration

scientific article published on 15 June 2013

Characterization of wet massing behavior of silicified microcrystalline cellulose and alpha-lactose monohydrate using near-infrared spectroscopy

scientific article published in January 2001

Chemical imaging and solid state analysis at compact surfaces using UV imaging

scientific article published on 31 October 2014

Chitosan-Based Nano-Embedded Microparticles: Impact of Nanogel Composition on Physicochemical Properties

scientific article published on 22 December 2016

Ciprofloxacin-loaded sodium alginate/poly (lactic-co-glycolic acid) electrospun fibrous mats for wound healing

scientific article published on 9 November 2017

Classification of lyophilised mixtures using multivariate analysis of NIR spectra.

scientific article

Colorimetry as Quality Control Tool for Individual Inkjet-Printed Pediatric Formulations

scientific article published on 13 October 2016

Comparison of the effects of two drying methods on polymorphism of theophylline

scientific article published in May 2004

Comparison of torque measurements and near-infrared spectroscopy in characterization of a wet granulation process

scientific article

Complementing high-throughput X-ray powder diffraction data with quantum-chemical calculations: Application to piroxicam form III.

scientific article

Computational Dehydration of Crystalline Hydrates Using Molecular Dynamics Simulations.

scientific article published on 15 November 2016

Correlation between calculated molecular descriptors of excipient amino acids and experimentally observed thermal stability of lysozyme.

scientific article published on 20 March 2017

Critical solvent properties affecting the particle formation process and characteristics of celecoxib-loaded plga microparticles via spray-drying.

scientific article published on 11 December 2012

Cryptopharmaceuticals: Increasing the Safety of Medication by a Blockchain of Pharmaceutical Products

scientific article published on 02 May 2019

Crystal Morphology Modification by the Addition of Tailor-Made Stereocontrolled Poly(N-isopropyl acrylamide)

article

Crystal morphology engineering of pharmaceutical solids: tabletting performance enhancement

scientific article published on 30 January 2009

Crystallization of a polymorphic hydrate system.

scientific article published in February 2010

Crystallization of glycine with ultrasound.

scientific article

Current advances and future trends in characterizing poorly water-soluble drugs using spectroscopic, imaging and data analytical techniques.

scientific article

Dehydration studies using a novel multichamber microscale fluid bed dryer with in-line near-infrared measurement

scientific article published in October 2003

Design space approach in the optimization of the spray-drying process

scientific article published on 29 September 2011

Designing CAF-adjuvanted dry powder vaccines: spray drying preserves the adjuvant activity of CAF01.

scientific article published on 8 February 2013

Detecting Blending End-Point Using Mean Squares Successive Difference Test and Near-Infrared Spectroscopy.

scientific article published on 10 June 2015

Detecting phase separation of freeze-dried binary amorphous systems using pair-wise distribution function and multivariate data analysis.

scientific article

Determination of amorphous content in the pharmaceutical process environment

scientific article published on 01 February 2007

Determining Thermal Conductivity of Small Molecule Amorphous Drugs with Modulated Differential Scanning Calorimetry and Vacuum Molding Sample Preparation

scientific article published on 10 December 2019

Development and characterization of aqueous amylose-rich maize starch dispersion for film formation.

scientific article published in September 2003

Development of an automation system for a tablet coater.

scientific article published in January 2002

Disproportionation of the calcium salt of atorvastatin in the presence of acidic excipients

scientific article published on 21 July 2012

Dissolution study of nanocrystal powders of a poorly soluble drug by UV imaging and channel flow methods

scientific article published on 30 August 2013

Dissolution testing of amorphous solid dispersions

scientific article published on 28 January 2013

Drug hydrate systems and dehydration processes studied by terahertz pulsed spectroscopy

scientific article published on 21 October 2006

Edible solid foams as porous substrates for inkjet-printable pharmaceuticals

scientific article published on 08 January 2019

Effect of ethanol as a co-solvent on the aerosol performance and stability of spray-dried lysozyme.

scientific article published on 9 September 2016

Effect of thermal and shear stresses in the spray drying process on the stability of siRNA dry powders

scientific article published on 08 May 2019

Effects of Water on Powder Flowability of Diverse Powders Assessed by Complimentary Techniques

scientific article published on 20 March 2019

Effects of excipients on hydrate formation in wet masses containing theophylline

scientific article published in March 2003

Effects of polymer additives on the crystallization of hydrates: a molecular-level modulation.

scientific article

Electrospinnability of Poly Lactic-co-glycolic Acid (PLGA): the Role of Solvent Type and Solvent Composition.

scientific article published on 24 January 2017

Engineering of an inhalable DDA/TDB liposomal adjuvant: a quality-by-design approach towards optimization of the spray drying process

scientific article

Enhanced dissolution rate and synchronized release of drugs in binary systems through formulation: Amorphous naproxen-cimetidine mixtures prepared by mechanical activation

scientific article

Establishing quantitative in-line analysis of multiple solid-state transformations during dehydration.

scientific article

Evaluating the effect of coating equipment on tablet film quality using terahertz pulsed imaging

scientific article published on 4 April 2013

Evaluation of droplet size distributions using univariate and multivariate approaches.

scientific article

Evaluation of ring shear testing as a characterization method for powder flow in small-scale powder processing equipment

scientific article published on 29 August 2014

Expedited Investigation of Powder Caking Aided by Rapid 3D Prototyping of Testing Devices

scientific article published on 03 August 2019

Exploring the Complexity of Processing-Induced Dehydration during Hot Melt Extrusion Using In-Line Raman Spectroscopy

scientific article published on 01 February 2020

Exploring the chemical space for freeze-drying excipients

scientific article published on 27 May 2019

Exploring the solid-form landscape of pharmaceutical hydrates: transformation pathways of the sodium naproxen anhydrate-hydrate system

scientific article

Factors affecting crystallization of hydrates

scientific article

Fast-track to a solid dispersion formulation using multi-way analysis of complex interactions.

scientific article

Foreign matter identification from solid dosage forms

scientific article published on 5 March 2013

Fuzzy Logic-based expert system for evaluating cake quality of freeze-dried formulations

scientific article

High-Throughput Fabrication of Nanocomplexes Using 3D-Printed Micromixers.

scientific article published on 6 December 2016

High-shear granulation as a manufacturing method for cocrystal granules

scientific article published on 16 May 2013

Hydrate formation during wet granulation studied by spectroscopic methods and multivariate analysis

scientific article published in September 2002

Hyphenated spectroscopy as a polymorph screening tool

scientific article published on 13 February 2007

Image Analytical Approach for Needle-Shaped Crystal Counting and Length Estimation

Image-Based Artificial Intelligence Methods for Product Control of Tablet Coating Quality

scientific article published on 15 September 2020

Imaging of dehydration in particulate matter using Raman line-focus microscopy

scientific article published on 17 May 2019

Implementation of a process analytical technology system in a freeze-drying process using Raman spectroscopy for in-line process monitoring

scientific article published on 27 September 2007

Improved understanding of factors contributing to quantification of anhydrate/hydrate powder mixtures

scientific article published on 01 July 2005

In situ measurement of solvent-mediated phase transformations during dissolution testing

scientific article published on 01 December 2006

In-line moisture measurement during granulation with a four-wavelength near infrared sensor: an evaluation of particle size and binder effects

scientific article published in September 2000

Increasing process understanding by analyzing complex interactions in experimental data

scientific article

Influence of Polymorphic Form, Morphology, and Excipient Interactions on the Dissolution of Carbamazepine Compacts

scientific article published on 01 March 2007

Influence of raw material properties upon critical quality attributes of continuously produced granules and tablets

scientific article published on 28 February 2014

Influence of solvent evaporation rate and formulation factors on solid dispersion physical stability

scientific article published on 17 October 2011

Influence of temperature on solvent-mediated anhydrate-to-hydrate transformation kinetics

scientific article published on 01 October 2010

Influence of the solid form of siramesine hydrochloride on its behavior in aqueous environments

scientific article

Inhalable co-amorphous budesonide-arginine dry powders prepared by spray drying

scientific article published on 15 April 2019

Insight into Nanoscale Network of Spray-Dried Polymeric Particles: Role of Polymer Molecular Conformation

scientific article published on 22 October 2018

Insight into the solubility and dissolution behavior of piroxicam anhydrate and monohydrate forms

scientific article published on 23 April 2012

Insights into the Early Dissolution Events of Amlodipine Using UV Imaging and Raman Spectroscopy

scientific article published on 20 June 2011

Integrated approach to study the dehydration kinetics of nitrofurantoin monohydrate

scientific article published on September 2010

Integration of personalized drug delivery systems into digital health

scientific article published in 2021

Intestinal mucosa permeability following oral insulin delivery using core shell corona nanolipoparticles

scientific article published on 07 September 2013

Investigating dehydration from compacts using terahertz pulsed, Raman, and near-infrared spectroscopy

scientific article

Investigation of factors affecting the stability of lysozyme spray dried from ethanol-water solutions.

scientific article published on 11 October 2017

Investigation of nanocarriers and excipients for preparation of nanoembedded microparticles

scientific article published on 04 May 2017

Investigation of solid phase composition on tablet surfaces by grazing incidence X-ray diffraction

scientific article published on 09 July 2011

Investigation of the phase separation of PNIPAM using infrared spectroscopy together with multivariate data analysis

Investigations on the effect of different cooling rates on the stability of amorphous indomethacin

scientific article

Melt Extrusion of High-Dose Co-Amorphous Drug-Drug Combinations : Theme: Formulation and Manufacturing of Solid Dosage Forms Guest Editors: Tony Zhou and Tonglei Li.

scientific article

Microcrystalline cellulose-water interaction--a novel approach using thermoporosimetry

scientific article published on 01 November 2001

Microfluidics-based self-assembly of peptide-loaded microgels: Effect of three dimensional (3D) printed micromixer design

scientific article published on 04 December 2018

Miniaturized Approach for Excipient Selection During the Development of Oral Solid Dosage Form

article

Modifying release characteristics from 3D printed drug-eluting products

scientific article

Modulating protein release profiles by incorporating hyaluronic acid into PLGA microparticles Via a spray dryer equipped with a 3-fluid nozzle.

scientific article

Molecular structure and impact of amorphization strategies on intrinsic dissolution of spray dried indomethacin

scientific article published on 13 December 2018

Monitoring lidocaine single-crystal dissolution by ultraviolet imaging

scientific article published on 8 March 2011

Monitoring of multiple solid-state transformations at tablet surfaces using multi-series near-infrared hyperspectral imaging and multivariate curve resolution

scientific article published on 20 April 2015

Monitoring tablet surface roughness during the film coating process

scientific article

Monitoring the Isothermal Dehydration of Crystalline Hydrates Using Low-Frequency Raman Spectroscopy

scientific article published on 06 January 2021

Multispectral UV imaging for fast and non-destructive quality control of chemical and physical tablet attributes

scientific article published on 3 December 2015

Multivariate data analysis as a fast tool in evaluation of solid state phenomena

scientific article

NIR transmission spectroscopy for rapid determination of lipid and lyoprotector content in liposomal vaccine adjuvant system CAF01.

scientific article published on 23 July 2008

Near infrared reflectance spectroscopy for the fast identification of PVC-based films.

scientific article published in July 2001

Near-infrared chemical imaging (NIR-CI) as a process monitoring solution for a production line of roll compaction and tableting

scientific article published on 25 April 2015

Near-infrared chemical imaging (NIR-CI) of 3D printed pharmaceuticals

scientific article

Near-infrared imaging for high-throughput screening of moisture induced changes in freeze-dried formulations

scientific article published on 24 March 2014

Near-infrared spectroscopy for cocrystal screening. A comparative study with Raman spectroscopy.

scientific article

New perspectives for visual characterization of pharmaceutical solids

scientific article published in January 2004

On-line rheological characterization of semi-solid formulations

scientific article published on 15 November 2018

One-step production of protein-loaded PLGA microparticles via spray drying using 3-fluid nozzle.

scientific article

Optimizing the crystal size and habit of beta-sitosterol in suspension.

scientific article published on January 2003

Oscillatory Shear Rheology in Examining the Drug-Polymer Interactions Relevant in Hot Melt Extrusion

scientific article published on 13 January 2016

Particle size dependence of polymorphism in spray-dried mannitol.

scientific article published on 14 June 2011

Pellet manufacturing by extrusion-spheronization using process analytical technology

scientific article published on 30 September 2005

Phase transformation of erythromycin A dihydrate during fluid bed drying

scientific article published on 01 September 2008

Phase transformations of amlodipine besylate solid forms

scientific article published on 22 February 2011

Phase transformations of erythromycin A dihydrate during pelletisation and drying

scientific article published on 21 December 2006

Physical changes of beta-sitosterol crystals in oily suspensions during heating

scientific article published on 19 October 2005

Physical stability and moisture sorption of aqueous chitosan-amylose starch films plasticized with polyols

scientific article

Physical stability of a microcrystalline beta-sitosterol suspension in oil.

scientific article published in July 2003

Polymer-mediated anti-solvent crystallization of nitrendipine: monodispersed spherical crystals and growth mechanism.

scientific article

Polymorph Screening Using Near-Infrared Spectroscopy

scientific article published in 2003

Polymorphic form of piroxicam influences the performance of amorphous material prepared by ball-milling

scientific article published on 14 March 2012

Prediction of aqueous solubility for a diverse set of organic compounds based on atom-type electrotopological state indices.

scientific article published in December 2000

Preface of EuPAT 7 Special Issue - Inventing Tomorrow's Development and Manufacturing

scientific article published on 01 July 2016

Process analytical applications of Raman spectroscopy.

scientific article published on February 2007

Process development for spray drying of sticky pharmaceuticals; case study of bioadhesive nicotine microparticles for compressed medicated chewing gum.

scientific article

Professor Peter York-A Distinguished Career in Powders, Processing, and Particle Design

scientific article published on 27 October 2016

Properties of the Sodium Naproxen-Lactose-Tetrahydrate Co-Crystal upon Processing and Storage.

scientific article published on 19 April 2016

QR encoded smart oral dosage forms by inkjet printing

scientific article published on 25 November 2017

Qualitative in situ analysis of multiple solid-state forms using spectroscopy and partial least squares discriminant modeling

scientific article published on 01 July 2007

Quality by design approach in the optimization of the spray-drying process.

scientific article

Quantification of Inkjet-Printed Pharmaceuticals on Porous Substrates Using Raman Spectroscopy and Near-Infrared Spectroscopy

scientific article published on 03 June 2019

Quantification of fragmentation of pharmaceutical materials after tableting

scientific article published on 02 November 2018

Quantification of microwave-induced amorphization of celecoxib in PVP tablets using transmission Raman spectroscopy.

scientific article published on 8 February 2018

Raman mapping of mannitol/lysozyme particles produced via spray drying and single droplet drying.

scientific article published on 13 December 2014

Raman spectroscopy for quantitative analysis of pharmaceutical solids.

scientific article published on February 2007

Raman spectroscopy in pharmaceutical product design

scientific article published on 11 April 2015

Rapid Assessment of Tablet Film Coating Quality by Multispectral UV Imaging

scientific article published on 13 October 2015

Rapid Prototyping of Miniaturized Powder Mixing Geometries

scientific article published in 2021

Rapid solid-state analysis of freeze-dried protein formulations using NIR and Raman spectroscopies

scientific article published on 21 January 2011

Real-time dissolution behavior of furosemide in biorelevant media as determined by UV imaging

scientific article

Real-time in vitro dissolution of 5-aminosalicylic acid from single ethyl cellulose coated extrudates studied by UV imaging

scientific article published on 27 April 2013

Rheology as a tool for evaluation of melt processability of innovative dosage forms

scientific article published on 06 February 2015

Roadmap to 3D-Printed Oral Pharmaceutical Dosage Forms: Feedstock Filament Properties and Characterization for Fused Deposition Modeling

scientific article published on 13 November 2018

Role of Solvent Selection on Crystal Habit of 5-Aminosalicylic Acid - Combined Experimental and Computational Approach

scientific article

Role of excipients in hydrate formation kinetics of theophylline in wet masses studied by near-infrared spectroscopy

scientific article

Role of excipients in the quantification of water in lyophilised mixtures using NIR spectroscopy

scientific article published on 24 January 2009

Role of excipients on solid-state properties of piroxicam during processing

scientific article published on 09 December 2011

Role of water in the physical stability of solid dosage formulations

scientific article published on 01 October 2005

Simultaneous UV imaging and raman spectroscopy for the measurement of solvent-mediated phase transformations during dissolution testing

Simultaneous measurement of liquid-phase and solid-phase transformation kinetics in rotating disc and channel flow cell dissolution devices

scientific article

Social aspects in additive manufacturing of pharmaceutical products

scientific article published on 28 November 2016

Solid Forms of Amlodipine Besylate: Physicochemical, Structural, and Thermodynamic Characterization

Solid form screening--a review.

scientific article published on 31 July 2008

Solid-state properties and relationship between anhydrate and monohydrate of baclofen

scientific article published on 01 September 2007

Solvent Diversity in Polymorph Screening

scientific article published on 01 June 2008

Solvent-mediated amorphous-to-crystalline transformation of nitrendipine in amorphous particle suspensions containing polymers

scientific article published on 29 March 2012

Solvent-mediated solid phase transformations of carbamazepine: Effects of simulated intestinal fluid and fasted state simulated intestinal fluid

scientific article published in March 2009

Stability of lysozyme incorporated into electrospun fibrous mats for wound healing

scientific article published on 07 January 2019

Stabilization of liposomes during drying

scientific article published on 04 February 2011

Strategic framework for education and training in Quality by Design (QbD) and process analytical technology (PAT).

scientific article published on 22 April 2016

Strategic funding priorities in the pharmaceutical sciences allied to Quality by Design (QbD) and Process Analytical Technology (PAT).

scientific article published on 26 June 2012

Structural Elucidation of Rapid Solution-Mediated Phase Transitions in Pharmaceutical Solids Using in Situ Synchrotron SAXS/WAXS

scientific article published on 14 August 2012

Structural basis for the transformation pathways of the sodium naproxen anhydrate-hydrate system

scientific article published on 20 August 2014

Structural characterisation and dehydration behaviour of siramesine hydrochloride

scientific article published on 01 October 2009

Structures of cefradine dihydrate and cefaclor dihydrate from DFT-D calculations

scientific article published on 19 October 2013

Tablet surface characterisation by various imaging techniques.

scientific article

Tailor-made solvents for pharmaceutical use? Experimental and computational approach for determining solubility in deep eutectic solvents (DES)

scientific article published on 31 October 2019

Tailored beads made of dissolved cellulose--investigation of their drug release properties.

scientific article published on 4 September 2013

Temperature-Modulated Micromechanical Thermal Analysis with Microstring Resonators Detects Multiple Coherent Features of Small Molecule Glass Transition

scientific article published on 13 February 2020

The Future of Pharmaceutical Manufacturing Sciences

scientific article

The Use of 3D Printed Molds to Cast Tablets with a Designed Disintegration Profile

scientific article published on 26 February 2019

The characterization of fluidization behavior using a novel multichamber microscale fluid bed

scientific article published on 01 March 2004

The effect of HPMC and MC as pore formers on the rheology of the implant microenvironment and the drug release in vitro.

scientific article published in September 2017

The effect of poly (lactic-co-glycolic) acid composition on the mechanical properties of electrospun fibrous mats.

scientific article published on 8 July 2017

The evaluation of physical properties of injection molded systems based on poly(ethylene oxide) (PEO).

scientific article published on 23 December 2016

The flow properties and presence of crystals in drug-polymer mixtures: Rheological investigation combined with light microscopy.

scientific article published on 11 June 2017

The influence of lysozyme on mannitol polymorphism in freeze-dried and spray-dried formulations depends on the selection of the drying process

scientific article published on 13 March 2013

The influence of thermal history on the physical behavior of poly(ethylene glycol) (PEG)

scientific article published on 15 November 2010

The use of molecular descriptors in the development of co-amorphous formulations.

scientific article published on 9 April 2018

Three-Dimensional Printing of Drug-Eluting Implants: Preparation of an Antimicrobial Polylactide Feedstock Material

Towards a robust water content determination of freeze-dried samples by near-infrared spectroscopy

scientific article published on 30 July 2010

Towards better process understanding: chemometrics and multivariate measurements in manufacturing of solid dosage forms.

scientific article published on 19 February 2013

Towards effective solid form screening

scientific article published in September 2010

Tracking Dehydration Mechanisms in Crystalline Hydrates with Molecular Dynamics Simulations

article

Transforming nanomedicine manufacturing toward Quality by Design and microfluidics.

scientific article published on 4 April 2018

Ultrasensitive Microstring Resonators for Solid State Thermomechanical Analysis of Small and Large Molecules

scientific article published on 05 December 2018

Understanding processing-induced phase transformations in erythromycin-PEG 6000 solid dispersions

scientific article published on 01 August 2006

Unidirectional drug release from 3D printed mucoadhesive buccal films using FDM technology: In vitro and ex vivo evaluation

scientific article published on 21 September 2019

Use of in-line near-infrared spectroscopy in combination with chemometrics for improved understanding of pharmaceutical processes.

scientific article published in January 2005

Use of roughness maps in visualisation of surfaces.

scientific article

Use of the near-infrared reflectance method for measurement of moisture content during granulation

scientific article published on 01 January 2000

Using 3D Printing for Rapid Prototyping of Characterization Tools for Investigating Powder Blend Behavior

scientific article published on 2 November 2017

Visualization and Non-Destructive Quantification of Inkjet-Printed Pharmaceuticals on Different Substrates Using Raman Spectroscopy and Raman Chemical Imaging.

scientific article

Visualization and prediction of porosity in roller compacted ribbons with near-infrared chemical imaging (NIR-CI).

scientific article

Visualization of a pharmaceutical unit operation: wet granulation

scientific article published in September 2004

Visualization of fluid-bed granulation with self-organizing maps.

scientific article published in January 2001

Well-plate freeze-drying: a high throughput platform for screening of physical properties of freeze-dried formulations

scientific article published on 13 January 2014

X-ray powder diffractometry in combination with principal component analysis--a tool for monitoring solid state changes

scientific article published on 07 May 2011