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List of works by John Wain

A clinical, microbiological, and pathological study of intestinal perforation associated with typhoid fever

scientific article published on 14 June 2004

A comparison of dense transposon insertion libraries in the Salmonella serovars Typhi and Typhimurium

scientific article

A conserved acetyl esterase domain targets diverse bacteriophages to the Vi capsular receptor of Salmonella enterica serovar Typhi

scientific article published on 3 September 2010

A deletion defining a common Asian lineage of Mycobacterium tuberculosis associates with immune subversion

scholarly article

A multiplex single nucleotide polymorphism typing assay for detecting mutations that result in decreased fluoroquinolone susceptibility in Salmonella enterica serovars Typhi and Paratyphi A.

scientific article published on 28 May 2010

A novel broadly applicable PCR-RFLP method for rapid identification and subtyping of H58 Salmonella Typhi.

scientific article

A randomized controlled comparison of azithromycin and ofloxacin for treatment of multidrug-resistant or nalidixic acid-resistant enteric fever

scientific article

A study of typhoid fever in five Asian countries: disease burden and implications for controls

scientific article

An H-NS-like stealth protein aids horizontal DNA transmission in bacteria

scientific article published in January 2007

An investigation of the diversity of strains of enteroaggregative Escherichia coli isolated from cases associated with a large multi-pathogen foodborne outbreak in the UK.

scientific article

Antibodies to the Vi capsule of Salmonella Typhi in the serum of typhoid patients and healthy control subjects from a typhoid endemic region.

scientific article

Antimicrobial drug resistance of Salmonella enterica serovar typhi in asia and molecular mechanism of reduced susceptibility to the fluoroquinolones

scientific article

Applying phylogenomics to understand the emergence of Shiga-toxin-producing Escherichia coli O157:H7 strains causing severe human disease in the UK.

scientific article published on 14 September 2015

Cases of typhoid fever imported into England, Scotland and Wales (2000-2003).

scientific article published on 2 October 2006

Changes in causes of acute gastroenteritis in the United Kingdom over 15 years: microbiologic findings from 2 prospective, population-based studies of infectious intestinal disease

scientific article published on 12 March 2012

Characterisation and distribution of a cryptic Salmonella typhi plasmid pHCM2.

scientific article published on May 2002

Characterization of non-classical quinolone resistance in Salmonella enterica serovar Typhi: Report of a novel mutation in gyrB gene and diagnostic challenges

scientific article published on December 2014

Characterization of the genomes of a diverse collection of Salmonella enterica serovar Typhimurium definitive phage type 104

scientific article published on 10 October 2008

Clonality, virulence and antimicrobial resistance of enteroaggregative Escherichia coli from Mirzapur, Bangladesh.

scientific article published on 25 September 2017

Community-acquired septicaemia in southern Viet Nam: the importance of multidrug-resistant Salmonella typhi

scientific article published on September 1998

Comparative analysis of ESBL-positive Escherichia coli isolates from animals and humans from the UK, The Netherlands and Germany

scientific article

Comparative trial of short-course ofloxacin for uncomplicated typhoid fever in Vietnamese children

scientific article published on March 2005

Comparison of two DNA microarrays for detection of plasmid-mediated antimicrobial resistance and virulence factor genes in clinical isolates of Enterobacteriaceae and non-Enterobacteriaceae

scientific article published on 30 March 2010

Complete Genome Sequence of the Campylobacter coli Clinical Isolate 15-537360.

scientific article published on 12 December 2013

Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18

scientific article

Composition, acquisition, and distribution of the Vi exopolysaccharide-encoding Salmonella enterica pathogenicity island SPI-7.

scientific article

Cytokine release by lipopolysaccharide-stimulated whole blood from patients with typhoid fever

scientific article published on 3 July 2002

Deep-seated resistance in relapsed paratyphoid fever.

scientific article

Detecting SNPs and estimating allele frequencies in clonal bacterial populations by sequencing pooled DNA.

scientific article published on 3 June 2009

Detection of Vi-negative Salmonella enterica serovar typhi in the peripheral blood of patients with typhoid fever in the Faisalabad region of Pakistan.

scientific article

Development and evaluation of a multiple-locus variable-number tandem-repeats analysis assay for subtyping Salmonella Typhi strains from sub-Saharan Africa.

scientific article published on 18 July 2017

Diversity among human non-typhoidal salmonellae isolates from Zimbabwe

scientific article published in August 2013

Double blind comparison of ibuprofen and paracetamol for adjunctive treatment of uncomplicated typhoid fever

scientific article published on March 2004

Drug susceptibility testing using molecular techniques can enhance tuberculosis diagnosis.

scientific article published in February 2008

Effect of deletion or overexpression of the 19-kilodalton lipoprotein Rv3763 on the innate response to Mycobacterium tuberculosis

scientific article published in October 2005

Emergence and characterization of Salmonella enterica serovar Typhimurium phage type DT191a

scientific article published on 23 June 2010

Emergence in Vietnam of Streptococcus pneumoniae resistant to multiple antimicrobial agents as a result of dissemination of the multiresistant Spain(23F)-1 clone

scientific article

Emergence of a globally dominant IncHI1 plasmid type associated with multiple drug resistant typhoid

scientific article published in July 2011

Emergence of highly fluoroquinolone-resistant Salmonella enterica serovar Typhi in a community-based fever surveillance from Kolkata, India

scientific article

Enteroaggregative Escherichia coli have evolved independently as distinct complexes within the E. coli population with varying ability to cause disease

scientific article

Enteroaggregative Escherichia coli related to uropathogenic clonal group A.

scientific article published on May 2007

Epidemic typhoid in vietnam: molecular typing of multiple-antibiotic-resistant Salmonella enterica serotype typhi from four outbreaks.

scientific article

Epidemiological evidence that garden birds are a source of human salmonellosis in England and Wales

scientific article

Evaluating the use of multilocus variable number tandem repeat analysis of Shiga toxin-producing Escherichia coli O157 as a routine public health tool in England

scientific article published on 17 January 2014

Evaluation of multiplex tandem PCR (MT-PCR) assays for the detection of bacterial resistance genes among Enterobacteriaceae in clinical urines

scientific article published on 01 February 2019

Evaluation of new-generation serologic tests for the diagnosis of typhoid fever: data from a community-based surveillance in Calcutta, India

scientific article

Evidence of evolving extraintestinal enteroaggregative Escherichia coli ST38 clone

scientific article published on November 2014

Exposure of Escherichia coli and Salmonella enterica serovar Typhimurium to triclosan induces a species-specific response, including drug detoxification.

scientific article published on 16 September 2009

First report of Salmonella enterica serotype paratyphi A azithromycin resistance leading to treatment failure.

scientific article published on 13 October 2010

Fluoroquinolone resistance in Salmonella Typhi

scientific article

Foreign travel and decreased ciprofloxacin susceptibility in Salmonella enterica infections

scientific article

Genes of the class II and class III major histocompatibility complex are associated with typhoid fever in Vietnam

scientific article published on 21 December 2000

Genomic characterisation of invasive non-typhoidal Salmonella enterica Subspecies enterica Serovar Bovismorbificans isolates from Malawi ⬇️

scientific article

Harnessing the genome: development of a hierarchical typing scheme for meticillin-resistant Staphylococcus aureus

scientific article published on 20 September 2012

High-throughput sequencing provides insights into genome variation and evolution in Salmonella Typhi

scientific article published on 27 July 2008

Host susceptibility and clinical outcomes in toll-like receptor 5-deficient patients with typhoid fever in Vietnam

scientific article published on 28 February 2005

Identification of bacterial pathogens and antimicrobial resistance directly from clinical urines by nanopore-based metagenomic sequencing.

scientific article published on 25 September 2016

Immunological monitoring to prevent and treat sepsis

scientific article

Improved multiplex PCR strategy for rapid assignment of the four major Escherichia coli phylogenetic groups.

scientific article

In vitro activity of rifaximin against clinical isolates of Escherichia coli and other enteropathogenic bacteria isolated from travellers returning to the UK.

scientific article published in March 2014

Infection biology of a novel alpha-crystallin of Mycobacterium tuberculosis: Acr2.

scientific article published on April 2005

Insight into Shiga toxin genes encoded by Escherichia coli O157 from whole genome sequencing

scientific article

International spread of an epidemic population of Salmonella enterica serotype Kentucky ST198 resistant to ciprofloxacin.

scientific article published on 2 August 2011

Intracontinental spread of human invasive Salmonella Typhimurium pathovariants in sub-Saharan Africa

scientific article

Investigating the link between the presence of enteroaggregative Escherichia coli and infectious intestinal disease in the United Kingdom, 1993 to 1996 and 2008 to 2009.

scientific article published on 12 September 2013

Isolation of Salmonella enterica subspecies enterica serovar Paratyphi B dT+, or Salmonella Java, from Indonesia and alteration of the d-tartrate fermentation phenotype by disrupting the ORF STM 3356.

scientific article

Massively parallel transposon mutagenesis identifies temporally essential genes for biofilm formation in Escherichia coli

scientific article published in 2021

MinION nanopore sequencing identifies the position and structure of a bacterial antibiotic resistance island

scientific article published on 8 December 2014

Molecular analysis of fluoroquinolone-resistant Salmonella Paratyphi A isolate, India

scientific article published on March 2006

Molecular analysis of incHI1 antimicrobial resistance plasmids from Salmonella serovar Typhi strains associated with typhoid fever

scientific article published on September 2003

Molecular characterization of the Salmonella enterica serovar Typhi Vi-typing bacteriophage E1.

scientific article

Molecular typing of multiple-antibiotic-resistant Salmonella enterica serovar Typhi from Vietnam: application to acute and relapse cases of typhoid fever

scientific article

Multi-locus sequence typing of enteroaggregative Escherichia coli isolates from Nigerian children uncovers multiple lineages

scientific article

Multidrug resistant Salmonella Concord is a major cause of salmonellosis in children in Ethiopia

scientific article published on January 2011

Multidrug-resistant Salmonella enterica serovar paratyphi A harbors IncHI1 plasmids similar to those found in serovar typhi.

scientific article published on 23 March 2007

Multilocus sequence typing analysis of Shigella flexneri isolates collected in Asian countries

scientific article

Multilocus sequence typing as a replacement for serotyping in Salmonella enterica

scientific article published in 2012

Nanopore metagenomics enables rapid clinical diagnosis of bacterial lower respiratory infection

scientific article published on 24 June 2019

National outbreak of Salmonella Enteritidis phage type 14b in England, September to December 2009: case-control study

scientific article published on 14 April 2011

Next-generation sequencing in clinical microbiology

scientific article published in April 2013

Nontyphoidal Salmonella serovars cause different degrees of invasive disease globally

scientific article published in February 2009

Optimisation of 16S rRNA gut microbiota profiling of extremely low birth weight infants.

scientific article published on 2 November 2017

Performance comparison of benchtop high-throughput sequencing platforms

scientific article

Population genetic structure of 4,12:a:- Salmonella enterica strains from harbor porpoises

scientific article

Population structure of Escherichia coli causing bacteraemia in the UK and Ireland between 2001 and 2010.

scientific article published on 5 May 2016

Prevalence of Salmonella enterica serovar 4,[5],12:i:- in England and Wales, 2010.

scientific article published on 13 September 2012

Prophage sequences defining hot spots of genome variation in Salmonella enterica serovar Typhimurium can be used to discriminate between field isolates

scientific article published on 23 May 2007

Pseudogene accumulation in the evolutionary histories of Salmonella enterica serovars Paratyphi A and Typhi

scientific article published on 21 January 2009

Public health value of next-generation DNA sequencing of enterohemorrhagic Escherichia coli isolates from an outbreak.

scientific article published on 7 November 2012

Quantification of IgM molecular response by droplet digital PCR as a potential tool for the early diagnosis of sepsis.

scientific article

Quantitation of Bacteria in Blood of Typhoid Fever Patients and Relationship between Counts and Clinical Features, Transmissibility, and Antibiotic Resistance ⬇️

scientific article published on June 1, 1998

Quantitation of bacteria in bone marrow from patients with typhoid fever: relationship between counts and clinical features

scientific article published on April 2001

Quinolone-resistant Salmonella typhi in Viet Nam: molecular basis of resistance and clinical response to treatment

scientific article published on December 1997

Quinolone-resistant Salmonella typhi in Vietnam

scientific article published in April 1998

RamA, a member of the AraC/XylS family, influences both virulence and efflux in Salmonella enterica serovar Typhimurium.

scientific article

Randomized controlled comparison of ofloxacin, azithromycin, and an ofloxacin-azithromycin combination for treatment of multidrug-resistant and nalidixic acid-resistant typhoid fever

scientific article published on 4 December 2006

Rapid evolution of fluoroquinolone-resistant Escherichia coli in Nigeria is temporally associated with fluoroquinolone use

scientific article

Rapid identification of major Escherichia coli sequence types causing urinary tract and bloodstream infections.

scientific article

Report of neonatal meningitis due to Salmonella enterica serotype Agona and review of breast milk-associated neonatal Salmonella infections

scientific article published on 15 July 2009

Revolutionising bacteriology to improve treatment outcomes and antibiotic stewardship

scientific article published on 29 March 2013

Risk factors for the development of severe typhoid fever in Vietnam

scientific article published on 10 February 2014

Risk factors for typhoid fever in the Mekong delta, southern Viet Nam: a case-control study

scientific article published on January 2001

Safety and efficacy of 2% chlorhexidine gluconate aqueous versus 2% chlorhexidine gluconate in 70% isopropyl alcohol for skin disinfection prior to percutaneous central venous catheter insertion in preterm neonates: the ARCTIC randomised-controlled f

scientific article published on 19 February 2019

Salmonella enterica subspecies II infections in England and Wales--the use of multilocus sequence typing to assist serovar identification

scientific article published on 2 April 2014

Salmonella paratyphi A rates, Asia

scientific article published in November 2005

Salmonella typhi, the causative agent of typhoid fever, is approximately 50,000 years old.

scientific article published on October 2002

Serodiagnosis of Salmonella enterica serovar Typhi and S. enterica serovars Paratyphi A, B and C human infections

scientific article

Serology of typhoid fever in an area of endemicity and its relevance to diagnosis

scientific article

Short course of ofloxacin for treatment of multidrug-resistant typhoid.

scientific article published on April 1995

Short courses of ofloxacin for the treatment of enteric fever

scientific article

Simultaneous assay of every Salmonella Typhi gene using one million transposon mutants

scientific article published on 13 October 2009

Specimens and culture media for the laboratory diagnosis of typhoid fever.

scientific article published on December 2008

Standardisation of multilocus variable-number tandem-repeat analysis (MLVA) for subtyping of Salmonella enterica serovar Enteritidis

scientific article published on 11 August 2011

Suitable disk antimicrobial susceptibility breakpoints defining Salmonella enterica serovar Typhi isolates with reduced susceptibility to fluoroquinolones

scientific article

Ten years experience of Salmonella infections in Cambridge, UK.

scientific article published on 09 October 2009

The Escherichia coli gene pool.

scientific article

The TCA cycle is not required for selection or survival of multidrug-resistant Salmonella

scientific article published on 20 December 2011

The acquisition of full fluoroquinolone resistance in Salmonella Typhi by accumulation of point mutations in the topoisomerase targets

scientific article published on 8 August 2006

The decline of typhoid and the rise of non-typhoid salmonellae and fungal infections in a changing HIV landscape: bloodstream infection trends over 15 years in southern Vietnam

scientific article

The emergence of multidrug resistance to antimicrobial agents for the treatment of typhoid fever

scientific article published on July 2004

The global consequence of disruption of the AcrAB-TolC efflux pump in Salmonella enterica includes reduced expression of SPI-1 and other attributes required to infect the host.

scientific article published on May 2009

The impact of JIDC

scientific article published on 23 July 2012

The influence of reduced susceptibility to fluoroquinolones in Salmonella enterica serovar Typhi on the clinical response to ofloxacin therapy

scientific article

The laboratory diagnosis of enteric fever.

scientific article published on December 2008

The molecular mechanisms of severe typhoid fever.

scientific article published on July 2001

The role of prophage-like elements in the diversity of Salmonella enterica serovars

scientific article published in May 2004

Transient Darwinian selection in Salmonella enterica serovar Paratyphi A during 450 years of global spread of enteric fever

scientific article

Typhoid and paratyphoid fever

Typhoid fever

scientific article (published 2015)

Typhoid fever and genetic polymorphisms at the natural resistance-associated macrophage protein 1.

scientific article published on March 2001

Typhoid fever in Ethiopia.

scientific article published on December 2008

Typhoid fever--important issues still remain

scientific article published on April 1998

Typhoid fever: pathogenesis and disease.

scientific article

Universal extraction method for gastrointestinal pathogens

scientific article published on 5 July 2013

Unlocking the genome of the human typhoid bacillus

scientific article

Use of paired serum samples for serodiagnosis of typhoid fever

scientific article

Using next generation sequencing to tackle non-typhoidal Salmonella infections

scientific article published on 15 January 2013

Variation in Salmonella enterica serovar typhi IncHI1 plasmids during the global spread of resistant typhoid fever

scientific article published on 17 November 2008

Vi antigen expression in Salmonella enterica serovar Typhi clinical isolates from Pakistan

scientific article published on March 2005

What's in a Name? Species-Wide Whole-Genome Sequencing Resolves Invasive and Noninvasive Lineages of Salmonella enterica Serotype Paratyphi B ⬇️

scientific article

Whole-genome sequencing for national surveillance of Shiga toxin-producing Escherichia coli O157.

scientific article

Why a special issue of JIDC on enteric fever?

scientific article published on 30 August 2008

Yersinia pestis pFra shows biovar-specific differences and recent common ancestry with a Salmonella enterica serovar Typhi plasmid

scientific article

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