List of works by Emilia Pedone

A biophysical characterization of the folded domains of KCTD12: insights into interaction with the GABAB2 receptor

scientific article

A new cryptic cationic antimicrobial peptide from human apolipoprotein E with antibacterial activity and immunomodulatory effects on human cells.

scientific article

A new cryptic host defense peptide identified in human 11-hydroxysteroid dehydrogenase-1 β-like: from in silico identification to experimental evidence

scientific article published on 25 April 2017

A novel arsenate reductase from the bacterium Thermus thermophilus HB27: its role in arsenic detoxification

scientific article published on 22 June 2013

A novel member of the protein disulfide oxidoreductase family from Aeropyrum pernix K1: structure, function and electrostatics

scientific article published on 28 July 2006

A physicochemical investigation on the metal binding properties of TtSmtB, a thermophilic member of the ArsR/SmtB transcription factor family

scientific article published on 26 July 2019

A selective αv β5 integrin antagonist hidden into the anophelin family protein cE5 from the malaria vector Anopheles gambiae

scholarly article published 1 March 2018

A single point mutation (Glu85Arg) increases the stability of the thioredoxin from Escherichia coli

scientific article published on 01 April 2001

A therapeutic approach to treat prostate cancer by targeting Nm23-H1/h-Prune interaction

scientific article published on 20 August 2014

An Integrated Structural and Computational Study of the Thermostability of Two Thioredoxin Mutants from Alicyclobacillus acidocaldarius

scientific article

Biochemical characterization of a novel thermostable β-glucosidase from Dictyoglomus turgidum.

scientific article published on 5 March 2018

Biochemical characterization of a thermostable endomannanase/endoglucanase from Dictyoglomus turgidum.

scientific article published on 25 November 2017

Biochemical phenotype of a common disease-causing mutation and a possible therapeutic approach for the phosphomannomutase 2-associated disorder of glycosylation

scientific article published on 27 March 2013

C68 from the Sulfolobus islandicus plasmid-virus pSSVx is a novel member of the AbrB-like transcription factor family

scientific article

Cell milieu significantly affects the fate of AApoAI amyloidogenic variants: predestination or serendipity?

scientific article published on 22 November 2017

Characterization of a multifunctional protein disulfide oxidoreductase from Sulfolobus solfataricus

scientific article

Computational analysis of the thermal stability in thioredoxins: a molecular dynamics approach.

scientific article published in October 1998

Conformational studies of retro-inverso peptides: The crystal and molecular structure of the hydantoin from H-Ala-G-Ala-mGly-OBzl

scientific article published on 01 November 1995

Crystal structure of the resuscitation-promoting factor (DeltaDUF)RpfB from M. tuberculosis

scientific article

Crystallization and preliminary X-ray diffraction studies of a protein disulfide oxidoreductase from Aeropyrum pernix K1

scientific article published on March 2005

Crystallization and preliminary X-ray diffraction studies of a protein disulfide oxidoreductase from Aquifex aeolicus

scientific article published on 20 October 2004

Cullin 3 Recognition Is Not a Universal Property among KCTD Proteins

scientific article published on 14 May 2015

Cullin3-BTB interface: a novel target for stapled peptides

scientific article published on 7 April 2015

Cystatin B Involvement in Synapse Physiology of Rodent Brains and Human Cerebral Organoids

scientific article published on 16 August 2019

Design and analysis of EphA2-SAM peptide ligands: A multi-disciplinary screening approach

scientific article published on 08 December 2018

Design, synthesis and characterization of a peptide able to bind proteins of the KCTD family: implications for KCTD-cullin 3 recognition

scientific article published on 24 March 2011

Dimerisation and structural integrity of Heparin Binding Hemagglutinin A from Mycobacterium tuberculosis: implications for bacterial agglutination

scientific article

Dynamical properties of cold shock protein A from Mycobacterium tuberculosis.

scientific article

Elucidating the role of the pLG72 R30K substitution in schizophrenia susceptibility

scientific article published on 6 February 2017

Evidence for an elongated dimeric structure of heparin-binding hemagglutinin from Mycobacterium tuberculosis

scientific journal article

Exploring the binding of d(GGGT)4 to the HIV-1 integrase: An approach to investigate G-quadruplex aptamer/target protein interactions.

scientific article

Exploring the catalytic mechanism of the first dimeric Bcp: Functional, structural and docking analyses of Bcp4 from Sulfolobus solfataricus

article by Danila Limauro et al published October 2010 in Biochimie

Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a resuscitation-promoting factor from Mycobacterium tuberculosis

scientific article published on 19 September 2007

Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the L,D-transpeptidase LdtMt1 from Mycobacterium tuberculosis

scientific article published on 22 February 2013

Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the resuscitation promoting factor interacting protein RipA from M. tuberculosis.

scientific article

Focusing on the functional characterization of the anserinase from Oreochromis niloticus

scientific article published on 22 February 2019

Folding mechanisms steer the amyloid fibril formation propensity of highly homologous proteins.

scientific article

Functional analyses yield detailed insight into the mechanism of thrombin inhibition by the antihemostatic salivary protein cE5 from Anopheles gambiae.

scientific article published on 7 June 2017

Functional and structural characterization of protein disulfide oxidoreductase from Thermus thermophilus HB27.

scientific article published on 18 May 2014

Functional properties of the protein disulfide oxidoreductase from the archaeon Pyrococcus furiosus: a member of a novel protein family related to protein disulfide-isomerase

scientific article

Heparin-binding hemagglutinin HBHA from Mycobacterium tuberculosis affects actin polymerisation

scientific article published on 06 June 2011

Heterotypic Sam-Sam association between Odin-Sam1 and Arap3-Sam: binding affinity and structural insights

scientific article published on 13 December 2012

High hydrostatic pressure-induced conformational changes in protein disulfide oxidoreductase from the hyperthermophilic archaeon Pyrococcus furiosus. A Fourier-transform infrared spectroscopic study

scientific article published on 9 August 2010

High-level expression of Aliciclobacillus acidocaldarius thioredoxin in Pichia pastoris and Bacillus subtilis

scientific article published in August 2003

Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation

scientific article

Identification and characterization of 1-Cys peroxiredoxin from Sulfolobus solfataricus and its involvement in the response to oxidative stress

scientific article published in February 2006

Insight into conformational modification of alpha-synuclein in the presence of neuronal whole cells and of their isolated membranes

scientific article

Insights into the anticancer properties of the first antimicrobial peptide from Archaea.

scientific article published on 15 June 2017

Insights into the catalytic mechanism of the Bcp family: functional and structural analysis of Bcp1 from Sulfolobus solfataricus

scientific article

Insights on a new PDI-like family: structural and functional analysis of a protein disulfide oxidoreductase from the bacterium Aquifex aeolicus

scientific article

Interaction of the N-(3-Methylpyridin-2-yl)amide Derivatives of Flurbiprofen and Ibuprofen with FAAH: Enantiomeric Selectivity and Binding Mode

scientific article published on 13 November 2015

Investigating the properties of TBA variants with twin thrombin binding domains

scientific article published on 24 June 2019

KCTD1: A novel modulator of adipogenesis through the interaction with the transcription factor AP2α

scientific article published on 26 August 2019

Mapping functional interaction sites of human prune C-terminal domain by NMR spectroscopy in human cell lysates.

scientific article published on 12 August 2013

Mapping key interactions in the dimerization process of HBHA from Mycobacterium tuberculosis, insights into bacterial agglutination.

scientific article published on 31 January 2012

Metastatic group 3 medulloblastoma is driven by PRUNE1 targeting NME1-TGF-β-OTX2-SNAIL via PTEN inhibition.

scientific article published on 27 February 2018

Molecular basis of the PED/PEA15 interaction with the C-terminal fragment of phospholipase D1 revealed by NMR spectroscopy.

scientific article published on 19 April 2013

Molecular basis of the scalp-ear-nipple syndrome unraveled by the characterization of disease-causing KCTD1 mutants

scientific article published on 19 July 2019

Molecular insights into the role of the polyalanine region in mediating PHOX2B aggregation

scientific article published on 16 April 2019

Molecular organization of the cullin E3 ligase adaptor KCTD11.

scientific article published on 13 January 2011

Molecular recognition of Cullin3 by KCTDs: Insights from experimental and computational investigations

scientific article published on 18 April 2014

Multiple catalytically active thioredoxin folds: a winning strategy for many functions

scientific article published on 13 July 2010

NMR backbone dynamics studies of human PED/PEA-15 outline protein functional sites

scientific article

NMR solution structure of a novel thioredoxin from Bacillus acidocaldarius

scientific article published in 2000

NMR solution structure of a novel thioredoxin from Bacillus acidocaldarius possible determinants of protein stability

scientific article

Neuroblastoma tumorigenesis is regulated through the Nm23-H1/h-Prune C-terminal interaction

scientific article

Novel propanamides as fatty acid amide hydrolase inhibitors.

scientific article published on 12 May 2017

Peptide Fragments of Odin-Sam1: Conformational Analysis and Interaction Studies with EphA2-Sam

scientific article

Peroxiredoxins as cellular guardians in Sulfolobus solfataricus: characterization of Bcp1, Bcp3 and Bcp4.

scientific article

Prediction and experimental testing of Bacillus acidocaldarius thioredoxin stability

scientific article published on April 1999

Proteins involved in sleep homeostasis: Biophysical characterization of INC and its partners.

scientific article published on 24 September 2016

Regulating levels of the neuromodulator d-serine in human brain: structural insight into pLG72 and d-amino acid oxidase interaction

scientific article published on 12 July 2016

Responding to toxic compounds: a genomic and functional overview of Archaea

scientific article published on January 2013

Sam domain-based stapled peptides: Structural analysis and interaction studies with the Sam domains from the EphA2 receptor and the lipid phosphatase Ship2

scientific article published on 20 July 2018

Selective Photo-Assisted Eradication of Triple-Negative Breast Cancer Cells through Aptamer Decoration of Doped Conjugated Polymer Nanoparticles

scientific article published in 2022

Sensing and adapting to environmental stress: the archaeal tactic

scientific article published in September 2004

Solution Structure of the First Sam Domain of Odin and Binding Studies with the EphA2 Receptor

scientific article

Solution structure and backbone dynamics of the K18G/R82E Alicyclobacillus acidocaldarius thioredoxin mutant: a molecular analysis of its reduced thermal stability

scientific article published in May 2004

Structural and functional studies of Stf76 from the Sulfolobus islandicus plasmid-virus pSSVx: a novel peculiar member of the winged helix-turn-helix transcription factor family

scientific article

Structural and thermal stability analysis of Escherichia coli and Alicyclobacillus acidocaldarius thioredoxin revealed a molten globule-like state in thermal denaturation pathway of the proteins: an infrared spectroscopic study

scientific article published on August 2003

Structural investigation of a C-terminal EphA2 receptor mutant: Does mutation affect the structure and interaction properties of the Sam domain?

scientific article published on 5 June 2017

Structural model of the hUbA1-UbcH10 quaternary complex: in silico and experimental analysis of the protein-protein interactions between E1, E2 and ubiquitin

scientific article published in 2014

Structure and functional regulation of RipA, a mycobacterial enzyme essential for daughter cell separation

scientific article

Structures of free and inhibited forms of the L,D-transpeptidase LdtMt1 from Mycobacterium tuberculosis

scientific article

Sulfolobus solfataricus protein disulphide oxidoreductase: insight into the roles of its redox sites

scientific article published on 6 November 2008

Sulfolobus solfataricus thiol redox puzzle: characterization of an atypical protein disulfide oxidoreductase

scientific article

Synthesis of diglycosylated (di)sulfides and comparative evaluation of their antiproliferative effect against tumor cell lines: A focus on the nature of sugar-recognizing mediators involved

scientific article published on 02 July 2019

Targeting EphA2-Sam and Its Interactome: Design and Evaluation of Helical Peptides Enriched in Charged Residues

scientific article published on 20 October 2016

Temperature-, SDS-, and pH-induced conformational changes in protein disulfide oxidoreductase from the archaeon Pyrococcus furiosus: a dynamic simulation and fourier transform infrared spectroscopic study

scientific article

The BTB domains of the potassium channel tetramerization domain proteins prevalently assume pentameric states

scientific journal article

The Sam-Sam interaction between Ship2 and the EphA2 receptor: design and analysis of peptide inhibitors

scientific article published on 12 December 2017

The essential player in adipogenesis GRP78 is a novel KCTD15 interactor.

scientific article published on 14 April 2018

The identification of a novel Sulfolobus islandicus CAMP-like peptide points to archaeal microorganisms as cell factories for the production of antimicrobial molecules

scientific article

The machinery for oxidative protein folding in thermophiles

scientific article published on January 2008

The prokaryotic Cys2His2 zinc-finger adopts a novel fold as revealed by the NMR structure of Agrobacterium tumefaciens Ros DNA-binding domain

scientific article

Thermal and chemical stability of two homologous POZ/BTB domains of KCTD proteins characterized by a different oligomeric organization.

scientific article published on 6 November 2013

Thioredoxin from Bacillus acidocaldarius: characterization, high-level expression in Escherichia coli and molecular modelling

scientific article published on November 1997

Ubiquitin binds the amyloid β peptide and interferes with its clearance pathways

scientific article published on 10 January 2019

gH625 is a viral derived peptide for effective delivery of intrinsically disordered proteins

scientific article published on 22 July 2013

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