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List of works by Geoffrey C. Nicholson

A carboxyl-terminal peptide from the parathyroid hormone-related protein inhibits bone resorption by osteoclasts.

scientific article

A multicenter, double-blind, one-year study comparing safety and efficacy of atorvastatin versus simvastatin in patients witb hypercholesterolemia

scientific article published on 01 July 1997

A novel serogenetic approach determines the community prevalence of celiac disease and informs improved diagnostic pathways.

scientific article

A quantitative cytochemical investigation of osteoclasts and multinucleate giant cells

scientific article published on April 1991

A randomized trial of sodium fluoride (60 mg) +/- estrogen in postmenopausal osteoporotic vertebral fractures: increased vertebral fractures and peripheral bone loss with sodium fluoride; concurrent estrogen prevents peripheral loss, but not [...]

scientific article

A systematic review: Identifying the prevalence rates of psychiatric disorder in Australia's Indigenous populations

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Actions of calcitonin, parathyroid hormone, and prostaglandin E2 on cyclic AMP formation in chicken and rat osteoclasts

scientific article published in January 1986

Adenoviral down-regulation of osteopontin inhibits human osteoclast differentiation in vitro

scientific article published on 01 November 2004

Alleles of RUNX2/CBFA1 gene are associated with differences in bone mineral density and risk of fracture

scientific article

Annual high-dose oral vitamin D and falls and fractures in older women: a randomized controlled trial

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Annual high-dose vitamin D3 and mental well-being: randomised controlled trial

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Antioxidant Vitamin Supplements and Markers of Bone Turnover in a Community Sample of Nonsmoking Women

scientific article published on 01 April 2006

Anxiety disorders and falls among older adults

scientific article published on 21 June 2016

Application of Epidemiology to Change Health Policy: Defining Age-Related Thresholds of Bone Mineral Density for Primary Prevention of Fracture

article

Area-based socioeconomic status and mood disorders: cross-sectional evidence from a cohort of randomly selected adult women.

scientific article published on 22 April 2011

Assessment of Fracture Risk

article

Association of Western and traditional diets with depression and anxiety in women

scientific article

Association of high-sensitivity C-reactive protein with de novo major depression

scientific article published in November 2010

Associations between measures of adiposity over 10 years and patella cartilage in population-based asymptomatic women

scientific article published on 9 April 2013

BMD in population-based adult women is associated with socioeconomic status.

scientific article published in May 2009

Behavioural and physical characteristics associated with vitamin D status in women.

scientific article

Beta-adrenergic blockers reduce the risk of fracture partly by increasing bone mineral density: Geelong Osteoporosis Study

scientific article published in January 2004

Biochemical and radiologic improvement in Paget's disease of bone treated with alendronate: A randomized, placebo-controlled trial

article

Biologically Active, Derivatizable Salmon Calcitonin Analog: Design, Synthesis, and Applications*

scientific article published on 01 September 1988

Bipolar disorder and adiposity: a study using whole body dual energy X-ray absorptiometry scans

scientific article published on 01 October 2011

Bone density changes in Paget's disease 2 years after iv pamidronate: profound, sustained increases in pagetic bone with severity-related loss in forearm nonpagetic cortical bone

scientific article published in January 2003

Bone mineral density is cross sectionally associated with cartilage volume in healthy, asymptomatic adult females: Geelong Osteoporosis Study

scientific article published on 30 June 2011

Bone mineral density reference ranges for Australian men: Geelong Osteoporosis Study.

scientific article published on 26 August 2009

Calcaneal ultrasound reference ranges for Australian men and women: the Geelong Osteoporosis Study.

scientific article published on 20 July 2012

Changes in gait performance over several years are associated with recurrent falls status in community-dwelling older women at high risk of fracture

scientific article published on 31 October 2014

Changes in hip fracture rates in southeastern Australia spanning the period 1994-2007.

scientific article published in July 2011

Changes in quality of life associated with fragility fractures: Australian arm of the International Cost and Utility Related to Osteoporotic Fractures Study (AusICUROS).

scientific article published on 20 March 2015

Citalopram and sertraline exposure compromises embryonic bone development

scientific article published on 8 September 2015

Clinical implications of the cytokine hypothesis of depression: the association between use of statins and aspirin and the risk of major depression

scientific article published on 2 August 2010

Clinical, biochemical, hematologic, and radiographic responses in Paget's disease following intravenous pamidronate disodium: a 2-year study

scientific article published on October 1996

Cohort profile: Geelong Osteoporosis Study

scientific article published on 3 November 2011

Complex Shape Changes in Isolated Rat Osteoclasts: Involvement of Protein Kinase C in the Response to Calcitonin

article

Cord blood-derived macrophage-lineage cells rapidly stimulate osteoblastic maturation in mesenchymal stem cells in a glycoprotein-130 dependent manner

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Cross-sectional analysis of association between socioeconomic status and utilization of primary total hip joint replacements 2006-7: Australian Orthopaedic Association National Joint Replacement Registry.

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Determinants of rural practice: positive interaction between rural background and rural undergraduate training

scientific article published on January 2015

Diet quality in bipolar disorder in a population-based sample of women

scientific article published in March 2011

Dietary Omega-3 Fatty Acids and Depression in a Community Sample

scientific article published on 01 April 2004

Dietary composition affects regional body fat distribution and levels of dehydroepiandrosterone sulphate (DHEAS) in post-menopausal women with Type 2 diabetes

scientific article

Dietary composition, body weight, and NIDDM. Comparison of high-fiber, high-carbohydrate, and modified-fat diets

scientific article published in March 1995

Dietary selenium and major depression: a nested case-control study

scientific article published on 30 January 2012

Diversity in fall characteristics hampers effective prevention: the precipitants, the environment, the fall and the injury.

scientific article published on 19 July 2017

Domain-specific mutations in sequestosome 1 (SQSTM1) cause familial and sporadic Paget's disease

scientific article published on 01 October 2002

Dominant negative MCP-1 blocks human osteoclast differentiation

scientific article published in February 2014

Effects of a multi-component exercise program and calcium-vitamin-D3-fortified milk on bone mineral density in older men: a randomised controlled trial

scientific article published on 28 October 2008

Efficacy and Safety of Oral Methazolamide in Patients With Type 2 Diabetes: A 24-Week, Placebo-Controlled, Double-Blind Study: Table 1

scientific article published on 14 August 2014

Erratum: Citalopram and sertraline exposure compromises embryonic bone development

scientific article published on 01 December 2015

Evaluation of the role of Valosin-containing protein in the pathogenesis of familial and sporadic Paget's disease of bone.

scientific article published on 30 September 2005

Evidence that protein kinase-A, calcium-calmodulin kinase and cytoskeletal proteins are involved in osteoclast retraction induced by calcitonin

article

Expression of functional RANK on mature rat and human osteoclasts

scientific article published on 01 December 1999

Falls and 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors

scientific article published on 01 November 2002

Familial Paget’s disease of bone: patterns of inheritance and frequency of linkage to chromosome 18q

scientific article published on 01 June 2000

Fra-1 potentiates osteoclastic differentiation in osteoclast-macrophage precursor cell lines

scientific article published on May 1999

Fracture Risk (FRISK) Score: Geelong Osteoporosis Study.

scientific article published on 23 August 2006

Fracture rates lower in rural than urban communities: the Geelong Osteoporosis Study

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Fracture risk among older men: osteopenia and osteoporosis defined using cut-points derived from female versus male reference data

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Fracture risk score and absolute risk of fracture

scientific article published on 3 February 2011

GM-CSF cannot substitute for M-CSF in human osteoclastogenesis.

scientific article published in August 2004

Gene array identification of osteoclast genes: differential inhibition of osteoclastogenesis by cyclosporin A and granulocyte macrophage colony stimulating factor

scientific article published on February 2004

Genetic analyses in a sample of individuals with high or low BMD shows association with multiple Wnt pathway genes

scientific article

Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium

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Genome-wide association identifies three new susceptibility loci for Paget's disease of bone.

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Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk

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Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

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Glutamine repeat variants in human RUNX2 associated with decreased femoral neck BMD, broadband ultrasound attenuation and target gene transactivation

scientific article

Habitual physical activity and the risk for depressive and anxiety disorders among older men and women.

scientific article published on 24 September 2010

Half the burden of fragility fractures in the community occur in women without osteoporosis. When is fracture prevention cost-effective?

scientific article published on 28 February 2006

Health Outcomes Associated with Hormone Therapy in Australian Women

article

High-sensitivity C-reactive protein and fracture risk in elderly women

scientific article published on 01 September 2006

Hormone therapy and risk of non-vertebral fracture: Geelong Osteoporosis Study

scientific article published on 14 February 2004

Identification of IDUA and WNT16 Phosphorylation-Related Non-Synonymous Polymorphisms for Bone Mineral Density in Meta-Analyses of Genome-Wide Association Studies

scientific article published on 08 August 2015

Identification of a Major Locus for Paget's Disease on Chromosome 10p13 in Families of British Descent

article

Identification of a novel FGFRL1 MicroRNA target site polymorphism for bone mineral density in meta-analyses of genome-wide association studies

scientific article published on 4 May 2015

Impact of denosumab on the peripheral skeleton of postmenopausal women with osteoporosis: bone density, mass, and strength of the radius, and wrist fracture

scientific article published in February 2013

Incident hip fracture and social disadvantage in an Australian population aged 50 years or greater.

scientific article published on 30 October 2010

Independent and Combined Effects of Calcium-Vitamin D3and Exercise on Bone Structure and Strength in Older Men: An 18-Month Factorial Design Randomized Controlled Trial

scientific article published on 05 January 2011

Induction of calcitonin receptors by 1 alpha, 25-dihydroxyvitamin D3 in osteoclast-like multinucleated cells formed from mouse bone marrow cells

scientific article

Interleukin-33, a target of parathyroid hormone and oncostatin m, increases osteoblastic matrix mineral deposition and inhibits osteoclast formation in vitro

scientific article published on March 2011

Intravenous pamidronate in Paget's disease—Response is dependent on radiographic and biochemical severity

scientific article published on 01 February 1994

Investigating the predictive ability of gait speed and quadriceps strength for incident falls in community-dwelling older women at high risk of fracture

scientific article published on 22 November 2013

Is High Dose Vitamin D Harmful?

scientific article published on December 19, 2012

Is high-dose vitamin d harmful? Authors' reply.

scientific article published on 8 March 2013

Leptin Inhibits Osteoclast Generation

scientific article published on 01 February 2002

Leptin directly regulates bone cell function in vitro and reduces bone fragility in vivo

scientific article published on 01 November 2002

Leptin in depressed women: cross-sectional and longitudinal data from an epidemiologic study.

scientific article

Lifestyle factors fail to explain the variation in plasma leptin concentrations in women

scientific article published in September 1998

Lifetime psychiatric disorders and body composition: a population-based study.

scientific article published on 26 February 2009

Long-term culture of disaggregated rat osteoclasts: inhibition of bone resorption and reduction of osteoclast-like cell number by calcitonin and PTHrP[107-139].

scientific article

Lower levels of physical activity in childhood associated with adult depression

scientific article published on 13 December 2010

M-CSF potently augments RANKL-induced resorption activation in mature human osteoclasts

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Monitoring falls in cohort studies of community-dwelling older women

scientific article published in April 2009

Morphometric vertebral fractures of the lower thoracic and lumbar spine, physical function and quality of life in men.

scientific article published on 19 September 2008

Multiple roles of M-CSF in human osteoclastogenesis

scientific article published on 01 October 2007

Multistage genome-wide association meta-analyses identified two new loci for bone mineral density

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Musculoskeletal deterioration in men accompanies increases in body fat.

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NFAT expression in human osteoclasts

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Novel UBA domain mutations of SQSTM1 in Paget's disease of bone: genotype phenotype correlation, functional analysis, and structural consequences

scientific article published on 22 March 2004

Opposite associations between alanine aminotransferase and γ-glutamyl transferase levels and all-cause mortality in type 2 diabetes: Analysis of the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study

scientific article

Oral contraceptives and bone mineral density: A population-based study

scientific article published on 01 February 2000

Osteoblast-mediated effects of zinc on isolated rat osteoclasts: Inhibition of bone resorption and enhancement of osteoclast number

scientific article published on 01 August 1996

Osteoblasts mediate thyroid hormone stimulation of osteoclastic bone resorption

scientific article published on 01 January 1994

Osteoclastic potential of human CFU-GM: biphasic effect of GM-CSF.

scientific article published on 16 December 2003

Osteoclasts from human giant cell tumors of bone lack estrogen receptors

scientific article published on 01 March 1998

Oxidative stress may be a common mechanism linking major depression and osteoporosis

scientific article published on 01 June 2008

Paracetamol (acetaminophen) use, fracture and bone mineral density

scientific article published on 17 March 2011

Parathyroid hormone-related protein-(107-139) inhibits bone resorption in vivo

scientific article published on 01 March 1997

Patterns of alcohol use and associated physical and lifestyle characteristics according to new Australian guidelines.

scientific article published on October 2010

Patterns of treatment in Australian men following fracture

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Polyalanine repeat polymorphism in RUNX2 is associated with site-specific fracture in post-menopausal females

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Potential role of the antioxidant N-acetylcysteine in slowing bone resorption in early post-menopausal women: a pilot study

scientific article published on 23 May 2007

Prevalence of Osteoporosis in Australian Women

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Prevalence of mood and anxiety disorder in self reported irritable bowel syndrome (IBS). An epidemiological population based study of women.

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Prevalence of obesity and the relationship between the body mass index and body fat: cross-sectional, population-based data

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Prevalence of osteoporosis in Australian men and women: Geelong Osteoporosis Study

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Prevention and treatment of glucocorticoid-induced osteoporosis: a comparison of calcitriol, vitamin D plus calcium, and alendronate plus calcium.

scientific article published on May 2003

RNA synthesis in isolated rat osteoclasts: Inhibitory effect of calcitonin

scientific article published on 01 January 1991

Rapid determination of vertebral fat fraction over a large range of vertebral bodies

scientific article

Seasonal periodicity of serum vitamin D and parathyroid hormone, bone resorption, and fractures: the Geelong Osteoporosis Study.

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Selective serotonin reuptake inhibitor use and bone mineral density in women with a history of depression

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Selective serotonin reuptake inhibitors inhibit human osteoclast and osteoblast formation and function

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Self-reported depression and cardiovascular risk factors in a community sample of women

scientific article published in January 2007

Social determinants of bone densitometry uptake for osteoporosis risk in patients aged 50yr and older: a systematic review

scientific article published on 09 February 2012

Socioeconomic status and bone mineral density in a population-based sample of men.

scientific article published on 4 January 2010

Socioeconomic status and risk factors for obesity and metabolic disorders in a population-based sample of adult females

scientific article published on 02 July 2009

Statin Use, Bone Mineral Density, and Fracture Risk

scientific article published on 01 March 2002

Susceptibility to Paget's disease of bone is influenced by a common polymorphic variant of osteoprotegerin

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Tartrate resistant acid phosphatase activity in rat cultured osteoclasts is inhibited by a carboxyl terminal peptide (osteostatin) from parathyroid hormone-related protein

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The Association Between Anxiety and Falls: A Meta-Analysis

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The Exclusion of High Trauma Fractures May Underestimate the Prevalence of Bone Fragility Fractures in the Community: The Geelong Osteoporosis Study

scientific article published on 01 August 1998

The human cost of fracture

scientific article published on 14 October 2005

The need for a culturally-tailored gatekeeper training intervention program in preventing suicide among Indigenous peoples: a systematic review

scientific article

The population burden of fractures originates in women with osteopenia, not osteoporosis

scientific article published on 13 May 2006

The prevalence of mood and anxiety disorders in Australian women.

scientific article published in June 2010

The rural pipeline to longer-term rural practice: General practitioners and specialists.

scientific article

Tobacco smoking as a risk factor for major depressive disorder: population-based study.

scientific article published in October 2008

Total and appendicular lean mass reference ranges for Australian men and women: the Geelong osteoporosis study

scientific article published on 05 January 2014

Trials and tribulations of recruiting 2,000 older women onto a clinical trial investigating falls and fractures: Vital D study

scientific article

Ubiquitin-associated domain mutations of SQSTM1 in Paget's disease of bone: evidence for a founder effect in patients of British descent.

scientific article published on 16 November 2004

Undercarboxylated osteocalcin, muscle strength and indices of bone health in older women

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Utilisation of primary total knee joint replacements across socioeconomic status in the Barwon Statistical Division, Australia, 2006-2007: a cross-sectional study

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Validity of 12-Month Falls Recall in Community-Dwelling Older Women Participating in a Clinical Trial.

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Vertebral Fracture Risk With Long-term Corticosteroid Therapy

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Vitamin D Action and Regulation of Bone Remodeling: Suppression of Osteoclastogenesis by the Mature Osteoblast

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WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk

scientific article published in July 2012

β-blockers reduce bone resorption marker in early postmenopausal women

scientific article published on 01 November 2005