List of works by Liesbeth Vandenput

A decade of FRAX: how has it changed the management of osteoporosis?

scientific article published on 11 February 2020

A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation

scientific article

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

scientific article published on 23 November 2016

A semiparametric Bayesian approach for structural equation models.

scientific article published in June 2010

ACE inhibitor use was associated with lower serum dehydroepiandrosterone concentrations in older men

scientific article

An aged rat model of partial androgen deficiency: prevention of both loss of bone and lean body mass by low-dose androgen replacement

scientific article published on 01 May 2000

Androgens and Bone

Androgens and glucuronidated androgen metabolites are associated with metabolic risk factors in men.

scientific article published on 21 August 2007

Androgens and osteoporosis.

scientific article

Assessment of gene-by-sex interaction effect on bone mineral density

scientific article (publication date: October 2012)

Association of SRD5A2 variants and serum androstane-3alpha,17beta-diol glucuronide concentration in Chinese elderly men.

scientific article published on 20 September 2010

Association of genetic variations in aromatase gene with serum estrogen and estrogen/testosterone ratio in Chinese elderly men.

scientific article published on 7 October 2009

BMD-Related Genetic Risk Scores Predict Site-Specific Fractures as Well as Trabecular and Cortical Bone Microstructure

scientific article published on 01 April 2020

Bone and muscle protective potential of the prostate-sparing synthetic androgen 7alpha-methyl-19-nortestosterone: evidence from the aged orchidectomized male rat model

scientific article published in April 2005

Causal relationship between obesity and serum testosterone status in men: A bi-directional mendelian randomization analysis

scientific article

Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts

scientific article (publication date: 2013)

Common Genetic Determinants of Vitamin D Insufficiency: A Genome-Wide Association Study

Common genetic determinants of vitamin D insufficiency: a genome-wide association study

scientific article

Comparable amounts of sex steroids are made outside the gonads in men and women: strong lesson for hormone therapy of prostate and breast cancer

scientific article

Comparisons of immunoassay and mass spectrometry measurements of serum estradiol levels and their influence on clinical association studies in men.

scientific article published on 30 April 2013

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 23 August 2017

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

DHEA and mortality: what is the nature of the association?

scientific article published on 02 April 2014

Dehydroepiandrosterone and its sulfate predict the 5-year risk of coronary heart disease events in elderly men.

scientific article

Disentangling the genetics of lean mass

article

Does bone resorption stimulate periosteal expansion? A cross-sectional analysis of β-C-telopeptides of type I collagen (CTX), genetic markers of the RANKL pathway, and periosteal circumference as measured by pQCT.

scientific article

Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms

scientific article

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

scientific article

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article published in November 2011

Estrogens as regulators of bone health in men.

scientific article published on 16 June 2009

Evidence for geographical and racial variation in serum sex steroid levels in older men.

scientific article

Evidence from the aged orchidectomized male rat model that 17beta-estradiol is a more effective bone-sparing and anabolic agent than 5alpha-dihydrotestosterone

scientific journal article

Evidence of a Causal Effect of Estradiol on Fracture Risk in Men

scientific article published on 01 February 2019

Genetic Determinants of Circulating Estrogen Levels, and Evidence of a Causal Effect of Estradiol on Bone Density in Men.

scientific article published on 9 January 2018

Genetic determinants of serum testosterone concentrations in men.

scientific article

Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure

scientific article

Genetic evidence of assortative mating in humans

article

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

scientific article published on 26 June 2011

Genetic variations in sex steroid-related genes as predictors of serum estrogen levels in men.

scientific article published on 30 December 2008

Genetics of endocrine disorders in the era of genome-wide association studies.

scientific article published on 3 July 2013

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

scientific article published in November 2018

Genome-wide Association Study for Radiographic Vertebral Fractures: A Potential Role for the 16q24 BMD Locus versus Lessons Learned from Challenging Phenotype Definition

Genome-wide association meta-analysis of cortical bone mineral density unravels allelic heterogeneity at the RANKL locus and potential pleiotropic effects on bone

scientific article

Genome-wide association studies on serum sex steroid levels

scientific article published on 28 March 2013

Genome-wide association study for radiographic vertebral fractures: a potential role for the 16q24 BMD locus

scientific article

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels

scientific article published on 17 January 2018

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

scientific article

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

scientific article

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

scientific article published on February 2016

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 27 April 2017

Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits ⬇️

scientific article published on 21 June 2016

High Serum SHBG Predicts Incident Vertebral Fractures in Elderly Men

scientific article published on 22 September 2015

High serum testosterone is associated with reduced risk of cardiovascular events in elderly men. The MrOS (Osteoporotic Fractures in Men) study in Sweden

scientific article published on October 2011

Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article

Hydroxysteroid (17β)-dehydrogenase 1-deficient female mice present with normal puberty onset but are severely subfertile due to a defect in luteinization and progesterone production

scientific article

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

scientific article published on 14 April 2013

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

scientific article

Limited clinical utility of a genetic risk score for the prediction of fracture risk in elderly subjects

scientific article

Low DHEAS levels are associated with depressive symptoms in elderly Chinese men: results from a large study.

scientific article published on 29 August 2011

Low Serum DHEAS Predicts Increased Fracture Risk in Older Men: The MrOS Sweden Study

scholarly article by Claes Ohlsson et al published 30 March 2017 in Journal of Bone and Mineral Research

Low Testosterone, but Not Estradiol, Is Associated With Incident Falls in Older Men: The International MrOS Study

scientific article published on 30 January 2017

Low serum levels of dehydroepiandrosterone sulfate predict all-cause and cardiovascular mortality in elderly Swedish men.

scientific article published on 7 July 2010

Low serum testosterone and estradiol predict mortality in elderly men.

scientific article published on 28 April 2009

Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis

scientific article

Measurement of a Comprehensive Sex Steroid Profile in Rodent Serum by High-Sensitive Gas Chromatography-Tandem Mass Spectrometry

scientific article published on 9 April 2015

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

Meta-analysis of genome-wide association studies identifies two loci associated with circulating osteoprotegerin levels

scientific article

Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus

scientific article

Meta‐Analysis of Genomewide Association Studies Reveals Genetic Variants for Hip Bone Geometry

scientific article published on 19 March 2019

Multi-ethnic fine-mapping of 14 central adiposity loci

scientific article

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

scientific article published on February 2016

Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2.

scientific article published in August 2016

OPG and RANK polymorphisms are both associated with cortical bone mineral density: findings from a metaanalysis of the Avon longitudinal study of parents and children and gothenburg osteoporosis and obesity determinants cohorts.

scientific article

Older men with low serum IGF-1 have an increased risk of incident fractures: the MrOS Sweden study

scientific article published in April 2011

Older men with low serum estradiol and high serum SHBG have an increased risk of fractures

scientific article published in October 2008

Peripheral blood leukocyte distribution and body mass index are associated with the methylation pattern of the androgen receptor promoter

scientific article

Preventing osteoporotic fractures with antiresorptive therapy: implications of microarchitectural changes

scientific article published on January 2004

Pubertal timing and adult fracture risk in men: A population-based cohort study

scientific article published on 02 December 2019

Quality control and conduct of genome-wide association meta-analyses

scientific article

Reply

Reversing sex steroid deficiency and optimizing skeletal development in the adolescent with gonadal failure

scientific article

Role of the androgen receptor in skeletal homeostasis: the androgen-resistant testicular feminized male mouse model

scientific article

SHBGGene Promoter Polymorphisms in Men Are Associated with Serum Sex Hormone-Binding Globulin, Androgen and Androgen Metabolite Levels, and Hip Bone Mineral Density

scientific article published on 22 August 2006

Serum estradiol associates with blood hemoglobin in elderly men: the MrOS Sweden study

scientific article

Serum estradiol is associated with lean mass in elderly Swedish men.

scientific article published on 8 January 2010

Serum estradiol levels are inversely associated with cortical porosity in older men.

scientific article

Serum levels of specific glucuronidated androgen metabolites predict BMD and prostate volume in elderly men.

scientific article published on February 2007

Sex steroid actions in male bone

scientific article

Sex steroid levels and cortical bone size in young men are associated with a uridine diphosphate glucuronosyltransferase 2B7 polymorphism (H268Y).

scientific article published on 19 June 2007

Sex steroid metabolism in the regulation of bone health in men.

scientific article published on 31 March 2010

Sex steroids and bone health in men.

scientific article published on 10 January 2012

Sex steroids and bone health in older Chinese men

scientific article

Skeletal effects of estrogen deficiency as induced by an aromatase inhibitor in an aged male rat model

article

Sleep Duration and Disturbances Were Associated With Testosterone Level, Muscle Mass, and Muscle Strength--A Cross-Sectional Study in 1274 Older Men.

scientific article published on 8 May 2015

Testosterone but not estradiol level is positively related to muscle strength and physical performance independent of muscle mass: a cross-sectional study in 1489 older men

scholarly article by Tung Wai Auyeung et al published May 2011 in European Journal of Endocrinology

Testosterone prevents orchidectomy-induced bone loss in estrogen receptor-alpha knockout mice

scientific article published in July 2001

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

The Uridine Diphosphate Glucuronosyltransferase 2B15 D85Y and 2B17 Deletion Polymorphisms Predict the Glucuronidation Pattern of Androgens and Fat Mass in Men

The estrogen receptor ligand ICI 182,780 does not impair the bone-sparing effects of testosterone in the young orchidectomized rat model

scientific article published on 28 January 2002

The gut microbiota is a major regulator of androgen metabolism in intestinal contents

scientific article published on 05 November 2019

The role of IGF-1 for fracture risk in men.

scientific article

The role of estrogens for male bone health

scientific article published on 20 March 2009

Update of the fracture risk prediction tool FRAX: a systematic review of potential cohorts and analysis plan

Use of age-dependent FRAX-based intervention thresholds for Singapore

scientific article published on 22 July 2020

WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk

scientific article published in July 2012

Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture

scientific article

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