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List of works by Alfredo Fusco

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BRAF mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary carcinomas

scientific article
Roles of HMGA proteins in cancer

scientific article published on December 2007
Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer

scientific article (publication date: October 2002)
MicroRNA deregulation in human thyroid papillary carcinomas.

scientific article published on June 2006
Specific microRNAs are downregulated in human thyroid anaplastic carcinomas

scientific article published on 11 June 2007
A new oncogene in human thyroid papillary carcinomas and their lymph-nodal metastases

scientific article published on July 1987
The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells

scientific article
Mutation of the PIK3CA gene in anaplastic thyroid cancer.

scientific article published on November 2005
HMGA2 induces pituitary tumorigenesis by enhancing E2F1 activity

scientific article
Increased BDNF promoter methylation in the Wernicke area of suicide subjects.

scientific article published in March 2010
DNA damage, homology-directed repair, and DNA methylation

scientific article published in July 2007
Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice

scientific article published on 29 May 2005
Nuclear phosphoproteins HMGA and their relationship with chromatin structure and cancer

scientific article published in September 2004
Aurora B overexpression associates with the thyroid carcinoma undifferentiated phenotype and is required for thyroid carcinoma cell proliferation

scientific article
Disease associated mutations at valine 804 in the RET receptor tyrosine kinase confer resistance to selective kinase inhibitors

scientific article published on August 2004
HMGA and cancer

scientific article published on January 2010
A cell proliferation and chromosomal instability signature in anaplastic thyroid carcinoma.

scientific article published in November 2007
RET/PTC activation in papillary thyroid carcinoma: European Journal of Endocrinology Prize Lecture

scientific article published in November 2006
Adenovirus-mediated suppression of HMGI(Y) protein synthesis as potential therapy of human malignant neoplasias

scholarly article
Expression of the RET/PTC fusion gene as a marker for papillary carcinoma in Hashimoto's thyroiditis

scientific article published on 01 January 1997
Upregulation of miR-21 by Ras in vivo and its role in tumor growth.

scientific article published on 18 October 2010
Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas

scientific article published in May 2005
Neoplastic transformation of rat thyroid cells requires the junB and fra-1 gene induction which is dependent on the HMGI-C gene product

scientific article
Haploinsufficiency of the Hmga1 gene causes cardiac hypertrophy and myelo-lymphoproliferative disorders in mice

scientific article published in March 2006
Analysis of the HMGI nuclear proteins in mouse neoplastic cells induced by different procedures

scientific article published in October 1989
CBX7 is a tumor suppressor in mice and humans

scientific article
Docking protein FRS2 links the protein tyrosine kinase RET and its oncogenic forms with the mitogen-activated protein kinase signaling cascade

scientific article published in July 2001
RET/papillary thyroid cancer rearrangement in nonneoplastic thyrocytes: follicular cells of Hashimoto's thyroiditis share low-level recombination events with a subset of papillary carcinoma.

scientific article published on 4 April 2006
MiR-1 is a tumor suppressor in thyroid carcinogenesis targeting CCND2, CXCR4, and SDF-1alpha

scientific article published on 13 July 2011
Altered microRNA expression profile in human pituitary GH adenomas: down-regulation of miRNA targeting HMGA1, HMGA2, and E2F1.

scientific article
Negative Regulation of BRCA1 Gene Expression by HMGA1 Proteins Accounts for the Reduced BRCA1 Protein Levels in Sporadic Breast Carcinoma

scientific article
Down-regulation of the miR-25 and miR-30d contributes to the development of anaplastic thyroid carcinoma targeting the polycomb protein EZH2.

scientific article
Rat protein tyrosine phosphatase eta suppresses the neoplastic phenotype of retrovirally transformed thyroid cells through the stabilization of p27(Kip1).

scientific article published on December 2000
Deregulation of microRNA expression in thyroid neoplasias

scientific article
Onset of natural killer cell lymphomas in transgenic mice carrying a truncated HMGI-C gene by the chronic stimulation of the IL-2 and IL-15 pathway

scientific article published on 26 June 2001
An increased high-mobility group A2 expression level is associated with malignant phenotype in pancreatic exocrine tissue

scientific article published on December 2003
RETRACTED: Critical role of the HMGI(Y) proteins in adipocytic cell growth and differentiation

retracted scientific article
A novel member of the BTB/POZ family, PATZ, associates with the RNF4 RING finger protein and acts as a transcriptional repressor

scientific article
Loss of the tumor suppressor gene PTEN marks the transition from intratubular germ cell neoplasias (ITGCN) to invasive germ cell tumors.

scientific article published on March 2005
UbcH10 overexpression may represent a marker of anaplastic thyroid carcinomas

scientific article
Inhibitory effects of peroxisome poliferator-activated receptor gamma on thyroid carcinoma cell growth

scientific article published on October 2002
Functional expression of the CXCR4 chemokine receptor is induced by RET/PTC oncogenes and is a common event in human papillary thyroid carcinomas

scientific article published in August 2004
HMGA proteins up-regulate CCNB2 gene in mouse and human pituitary adenomas

scientific journal article
Deregulation of microRNA expression in follicular-cell-derived human thyroid carcinomas

scientific article published on 29 January 2010
Loss of the CBX7 protein expression correlates with a more aggressive phenotype in pancreatic cancer

scientific article published on 23 February 2010
HMGA1 protein overexpression in human breast carcinomas: correlation with ErbB2 expression

scientific article
Downregulation of HMGA-targeting microRNAs has a critical role in human pituitary tumorigenesis

scientific article
Familial cancer associated with a polymorphism in ARLTS1

scientific article (publication date: 21 April 2005)
UbcH10 expression may be a useful tool in the prognosis of ovarian carcinomas

scientific article published on 2 October 2006
Chromobox protein homologue 7 protein, with decreased expression in human carcinomas, positively regulates E-cadherin expression by interacting with the histone deacetylase 2 protein

scientific journal article

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