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List of works by Alfredo Fusco

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Identification of a New Pathway for Tumor Progression: MicroRNA-181b Up-Regulation and CBX7 Down-Regulation by HMGA1 Protein

scientific article published on March 2010
Histone deacetylase inhibitors induce thyroid cancer-specific apoptosis through proteasome-dependent inhibition of TRAIL degradation.

scientific article published on 5 October 2009
Functional variants of the HMGA1 gene and type 2 diabetes mellitus

scientific article published in March 2011
Mir-23b and miR-130b expression is downregulated in pituitary adenomas

scientific article published on 28 March 2014
Phosphorylation of high-mobility group protein A2 by Nek2 kinase during the first meiotic division in mouse spermatocytes

scientific journal article
PATZ1 gene has a critical role in the spermatogenesis and testicular tumours

scientific journal article
A miRNA signature associated with human metastatic medullary thyroid carcinoma.

scientific article published on 14 October 2013
The loss of the CBX7 gene expression represents an adverse prognostic marker for survival of colon carcinoma patients.

scientific article
Efficient inhibition of RET/papillary thyroid carcinoma oncogenic kinases by 4-amino-5-(4-chloro-phenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2).

scientific article
TAZ/WWTR1 is overexpressed in papillary thyroid carcinoma

scientific article
HMGA1 protein over-expression is a frequent feature of epithelial ovarian carcinomas

scientific article published on 9 May 2003
HMGA2 mRNA expression correlates with the malignant phenotype in human thyroid neoplasias

scientific article
HMGA2: A pituitary tumour subtype-specific oncogene?

scientific article published on 27 March 2010
The insulin receptor: a new anticancer target for peroxisome proliferator-activated receptor-gamma (PPARgamma) and thiazolidinedione-PPARgamma agonists.

scientific article published on March 2008
HMGA1 and HMGA2 protein expression correlates with advanced tumour grade and lymph node metastasis in pancreatic adenocarcinoma

scientific article published on 01 February 2012
The homeodomain-interacting protein kinase 2 gene is expressed late in embryogenesis and preferentially in retina, muscle, and neural tissues

scientific article
Dysfunction of the RET receptor in human cancer

scientific article
Thyroid cell transformation inhibits the expression of a novel rat protein tyrosine phosphatase

scientific article published on August 1997
UbcH10 is overexpressed in malignant breast carcinomas

scientific article
RET activation and clinicopathologic features in poorly differentiated thyroid tumors

scientific article published in January 2002
HIPK2 controls cytokinesis and prevents tetraploidization by phosphorylating histone H2B at the midbody

scientific article
The tyrosine phosphatase PTPRJ/DEP-1 genotype affects thyroid carcinogenesis

scientific article published in November 2004
Genetic ablation of Ptprj, a mouse cancer susceptibility gene, results in normal growth and development and does not predispose to spontaneous tumorigenesis

scientific article
The beta-catenin axis integrates multiple signals downstream from RET/papillary thyroid carcinoma leading to cell proliferation.

scientific article published on 17 February 2009
Fra-1 promotes growth and survival in RAS-transformed thyroid cells by controlling cyclin A transcription

scientific journal article
FRA-1 protein overexpression is a feature of hyperplastic and neoplastic breast disorders

scientific article published on 25 January 2007
Restoration of receptor-type protein tyrosine phosphatase eta function inhibits human pancreatic carcinoma cell growth in vitro and in vivo

scientific article published on July 2004
Genetic alterations in thyroid carcinoma associated with familial adenomatous polyposis: clinical implications and suggestions for early detection

scientific article published on 01 December 1998
The insulin receptor substrate (IRS)-1 recruits phosphatidylinositol 3-kinase to Ret: evidence for a competition between Shc and IRS-1 for the binding to Ret.

scientific article published on January 2001
Chromatin and DNA methylation dynamics during retinoic acid-induced RET gene transcriptional activation in neuroblastoma cells.

scientific article published on 15 October 2010
Point mutation of the RET proto-oncogene in the TT human medullary thyroid carcinoma cell line

scientific article published on February 1995
The expression of the phosphotyrosine phosphatase DEP-1/PTPeta dictates the responsivity of glioma cells to somatostatin inhibition of cell proliferation

scientific article
The RET/PTC oncogene is frequently activated in oncocytic thyroid tumors (Hurthle cell adenomas and carcinomas), but not in oncocytic hyperplastic lesions

scientific article published on 01 January 2002
RET/PTC activation in hyalinizing trabecular tumors of the thyroid

scientific article published on 01 December 2000
Regulation of BRCA1 transcription by specific single-stranded DNA binding factors

scientific article
High-mobility group A1 proteins regulate p53-mediated transcription of Bcl-2 gene

scientific article published on 08 June 2010
Conditional expression of RET/PTC induces a weak oncogenic drive in thyroid PCCL3 cells and inhibits thyrotropin action at multiple levels

scientific article published on 10 April 2003
Reduced E-cadherin expression contributes to the loss of p27kip1-mediated mechanism of contact inhibition in thyroid anaplastic carcinomas.

scientific article published on 17 February 2005
High-mobility group A1 proteins are overexpressed in human leukaemias

scientific article published on May 2003
miR-191 down-regulation plays a role in thyroid follicular tumors through CDK6 targeting.

scientific article published on 28 September 2011
PATZ1 interacts with p53 and regulates expression of p53-target genes enhancing apoptosis or cell survival based on the cellular context

scientific article published on 12 December 2013
Down-regulation of oestrogen receptor-β associates with transcriptional co-regulator PATZ1 delocalization in human testicular seminomas.

scientific article published on 7 March 2011
Involvement of H4(D10S170) protein in ATM-dependent response to DNA damage.

scientific article
The High Mobility Group A proteins contribute to thyroid cell transformation by regulating miR-603 and miR-10b expression

scientific article published on 17 January 2013
RET expression in papillary thyroid cancer from patients irradiated in childhood for benign conditions.

scientific article published in August 2002
Iodide symporter gene expression in normal and transformed rat thyroid cells

scientific article published in May 1999
Activator protein-2 overexpression accounts for increased insulin receptor expression in human breast cancer.

scientific article published on May 2006
Detection of high-mobility group proteins A1 and A2 represents a valid diagnostic marker in post-pubertal testicular germ cell tumours

article
Molecular profile of hyalinizing trabecular tumours of the thyroid: high prevalence of RET/PTC rearrangements and absence of B-raf and N-ras point mutations

scientific article
The RFG oligomerization domain mediates kinase activation and re-localization of the RET/PTC3 oncoprotein to the plasma membrane

scientific article published on February 2001

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