List of works - Demetres D. Leonidas

1-(3-Deoxy-3-fluoro-beta-d-glucopyranosyl) pyrimidine derivatives as inhibitors of glycogen phosphorylase b: Kinetic, crystallographic and modelling studies

scientific article

3'-axial CH2 OH substitution on glucopyranose does not increase glycogen phosphorylase inhibitory potency. QM/MM-PBSA calculations suggest why

scientific article

A multidisciplinary study of 3-(β-d-glucopyranosyl)-5-substituted-1,2,4-triazole derivatives as glycogen phosphorylase inhibitors: Computation, synthesis, crystallography and kinetics reveal new potent inhibitors.

scientific article published on 2 February 2018

Affinity crystallography reveals binding of pomegranate juice anthocyanins at the inhibitor site of glycogen phosphorylase: the contribution of sugar moiety to potency and its implications to binding mode

scientific article published on 25 August 2020

Affinity crystallography reveals the bioactive compounds of industrial juicing byproducts of Punica granatum for glycogen phosphorylase.

scientific article published on 18 June 2017

Amide-1,2,3-triazole bioisosterism: the glycogen phosphorylase case

An evaluation of indirubin analogues as phosphorylase kinase inhibitors.

scientific article published on 3 August 2015

Anopheles gambiae odorant binding protein crystal complex with the synthetic repellent DEET: implications for structure-based design of novel mosquito repellents

scientific article

AtHESPERIN: a novel regulator of circadian rhythms with poly(A)-degrading activity in plants.

scientific article published on 30 November 2015

Binding of N-acetyl-N '-beta-D-glucopyranosyl urea and N-benzoyl-N '-beta-D-glucopyranosyl urea to glycogen phosphorylase b: kinetic and crystallographic studies

scientific article

Binding of beta-D-glucopyranosyl bismethoxyphosphoramidate to glycogen phosphorylase b: kinetic and crystallographic studies

scientific article published in February 2005

Binding of oxalyl derivatives of beta-d-glucopyranosylamine to muscle glycogen phosphorylase b.

scientific article published on 7 February 2006

Binding of phosphate and pyrophosphate ions at the active site of human angiogenin as revealed by X-ray crystallography

scientific article

Binding of the potential antitumour agent indirubin-5-sulphonate at the inhibitor site of rabbit muscle glycogen phosphorylase b. Comparison with ligand binding to pCDK2-cyclin A complex

scientific article

Binding ofN-acetyl-N ′-β-d-glucopyranosyl urea andN-benzoyl-N ′-β-d-glucopyranosyl urea to glycogen phosphorylaseb

scientific article published in 2002

Bioactivity of glycogen phosphorylase inhibitors that bind to the purine nucleoside site

scientific article

Biochemical and biological assessment of the inhibitory potency of extracts from vinification byproducts of Vitis vinifera extracts against glycogen phosphorylase

scientific article

Biochemical and in silico identification of the active site and the catalytic mechanism of the circadian deadenylase HESPERIN

scientific article published on 23 October 2020

Charcot-Leyden crystal protein (galectin-10) is not a dual function galectin with lysophospholipase activity but binds a lysophospholipase inhibitor in a novel structural fashion

scientific article

Cleavage of 3',5'-pyrophosphate-linked dinucleotides by ribonuclease A and angiogenin

scientific article

Computation as a tool for glycogen phosphorylase inhibitor design

scientific article published on October 2010

Control of phosphorylase b conformation by a modified cofactor: crystallographic studies on R-state glycogen phosphorylase reconstituted with pyridoxal 5'-diphosphate ⬇️

scientific article published on September 1, 1992

Crystal structure of eosinophil cationic protein at 2.4 A resolution

scientific article

Crystal structure of human Charcot-Leyden crystal protein, an eosinophil lysophospholipase, identifies it as a new member of the carbohydrate-binding family of galectins

scientific article

Crystal structure of rabbit muscle glycogen phosphorylase a in complex with a potential hypoglycaemic drug at 2.0 A resolution

scientific article (publication date: 11 April 2003)

Crystal structures of ribonuclease A complexes with 5'-diphosphoadenosine 3'-phosphate and 5'-diphosphoadenosine 2'-phosphate at 1.7 A resolution

scientific article

Crystallization and preliminary X-ray crystallographic analysis ofSclerotium rolfsiilectin

scientific article published on 23 January 2003

Crystallization and preliminary investigations on a telomeric repeat sequence C4A2C4A2.

scientific article published on 25 May 2001

Crystallographic and computational studies on 4-phenyl-N-(beta-D-glucopyranosyl)-1H-1,2,3-triazole-1-acetamide, an inhibitor of glycogen phosphorylase: comparison with alpha-D-glucose, N-acetyl-beta-D-glucopyranosylamine and [...]

scientific article

Crystallographic studies on N-azidoacetyl-β-d-glucopyranosylamine, an inhibitor of glycogen phosphorylase: Comparison with N-acetyl-β-d-glucopyranosylamine

scientific article published on 17 April 2006

Crystallographic studies on acyl ureas, a new class of glycogen phosphorylase inhibitors, as potential antidiabetic drugs.

scientific article

Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency

scientific article

Crystallographic studies on two bioisosteric analogues, N-acetyl-beta-D-glucopyranosylamine and N-trifluoroacetyl-beta-D-glucopyranosylamine, potent inhibitors of muscle glycogen phosphorylase

scientific article

Design of inhibitors of glycogen phosphorylase: a study of alpha- and beta-C-glucosides and 1-thio-beta-D-glucose compounds

scientific article

Editorial: Role of Ribonucleases in Immune Response Regulation During Infection and Cancer

scientific article published on 19 February 2020

Evidence for novel action at the cell binding site of human Angiogenin revealed by heteronuclear NMR spectroscopy, in silico and in vivo studies.

scientific article published on 4 January 2018

FR258900, a potential anti-hyperglycemic drug, binds at the allosteric site of glycogen phosphorylase

scientific article

Glucopyranosylidene-spiro-imidazolinones, a New Ring System: Synthesis and Evaluation as Glycogen Phosphorylase Inhibitors by Enzyme Kinetics and X-ray Crystallography

scientific article published on 28 June 2019

Glucopyranosylidene-spiro-iminothiazolidinone, a new bicyclic ring system: synthesis, derivatization, and evaluation for inhibition of glycogen phosphorylase by enzyme kinetic and crystallographic methods

scientific article

Glucose-based spiro-isoxazolines: a new family of potent glycogen phosphorylase inhibitors

scientific article

Glycogen phosphorylase as a target for type 2 diabetes: synthetic, biochemical, structural and computational evaluation of novel N-acyl-N´-(β-D-glucopyranosyl) urea inhibitors

scientific article

Guest-host crosstalk in an angiogenin-RNase A chimeric protein

scientific article

Halogen-substituted (C-β-D-glucopyranosyl)-hydroquinone regioisomers: synthesis, enzymatic evaluation and their binding to glycogen phosphorylase

scientific article

High Consistency of Structure-Based Design and X-Ray Crystallography: Design, Synthesis, Kinetic Evaluation and Crystallographic Binding Mode Determination of Biphenyl--acyl-β-d-Glucopyranosylamines as Glycogen Phosphorylase Inhibitors

scientific article published on 03 April 2019

High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors

scientific article

Iminosugars as potential inhibitors of glycogenolysis: structural insights into the molecular basis of glycogen phosphorylase inhibition

scientific article published on 01 September 2006

In the Search of Glycogen Phosphorylase Inhibitors: Synthesis of C-D-Glycopyranosylbenzo(hydro)quinones – Inhibition of and Binding to Glycogen Phosphorylase in the Crystal

Indirubin-3-Aminooxy-Acetate Inhibits Glycogen Phosphorylase by Binding at the Inhibitor and the Allosteric Site. Broad Specificities of the Two Sites

Influence of naturally-occurring 5â ²-pyrophosphate-linked substituents on the binding of adenylic inhibitors to ribonuclease a: An X-ray crystallographic study

scientific article

Inhibition of rabbit muscle glycogen phosphorylase by D-gluconohydroximo-1,5-lactone-N-phenylurethane

scientific article

Inhibitor design for ribonuclease A: the binding of two 5'-phosphate uridine analogues.

scientific article published on 27 June 2009

Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1, 3, 4-oxadiazole, -benzothiazole, and -benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site.

scientific article

Kinetic properties of tetrameric glycogen phosphorylase b in solution and in the crystalline state ⬇️

scientific article published on September 1, 1992

Mapping the ribonucleolytic active site of bovine seminal ribonuclease. The binding of pyrimidinyl phosphonucleotide inhibitors

scientific article

Molecular Cloning, Carbohydrate Specificity and the Crystal Structure of Two Sclerotium rolfsii Lectin Variants

scientific article

Morpholino, piperidino, and pyrrolidino derivatives of pyrimidine nucleosides as inhibitors of ribonuclease A: synthesis, biochemical, and crystallographic evaluation

scientific article

N-(4-Substituted-benzoyl)-N′-(β-d-glucopyranosyl)ureas as inhibitors of glycogen phosphorylase: Synthesis and evaluation by kinetic, crystallographic, and molecular modelling methods

scientific article published on 20 January 2012

NMR study of Met-1 human Angiogenin: (1)H, (13)C, (15)N backbone and side-chain resonance assignment

scientific article published on 13 September 2016

Nanomolar Inhibitors of Glycogen Phosphorylase Based on β-d-Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography Study

scientific article published on 19 September 2017

Natural flavonoids as antidiabetic agents. The binding of gallic and ellagic acids to glycogen phosphorylase b

scientific article

Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies

scientific article

New inhibitors of glycogen phosphorylase as potential antidiabetic agents.

scientific article published on January 2008

Nicotinic Cholinergic System and COVID-19: In Silico Identification of an Interaction between SARS-CoV-2 and Nicotinic Receptors with Potential Therapeutic Targeting Implications

scientific article published on 13 August 2020

Nicotinic cholinergic system and COVID-19: <i>In silico</i> evaluation of nicotinic acetylcholine receptor agonists as potential therapeutic interventions

scientific article published on 19 December 2020

Oxidation of human serum albumin exhibits inter-individual variability after an ultra-marathon mountain race

scientific article published on 28 March 2017

Phytogenic Polyphenols as Glycogen Phosphorylase Inhibitors: The Potential of Triterpenes and Flavonoids for Glycaemic Control in Type 2 Diabetes.

scientific article published on 18 November 2016

Potential interference of aluminum chlorohydrate with estrogen receptor signaling in breast cancer cells.

scientific article published in January 2018

Probing the β-pocket of the active site of human liver glycogen phosphorylase with 3-(C-β-d-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors.

scientific article published on 12 February 2018

Proteomic analysis of human Angiogenin interactions reveals cytoplasmic PCNA as a putative binding partner

scientific article

Recognition of ribonuclease A by 3'-5'-pyrophosphate-linked dinucleotide inhibitors: a molecular dynamics/continuum electrostatics analysis.

scientific article published on December 2006

Selective Recognition of Mannose by the Human Eosinophil Charcot-Leyden Crystal Protein (Galectin-10): A Crystallographic Study at 1.8 Å Resolution

scientific article

Sourcing the affinity of flavonoids for the glycogen phosphorylase inhibitor site via crystallography, kinetics and QM/MM-PBSA binding studies: comparison of chrysin and flavopiridol

scientific article

Structural Basis for the Recognition of Carbohydrates by Human Galectin-7, ⬇️

scientific article published on October 6, 1998

Structural analysis of the Rhizoctonia solani agglutinin reveals a domain-swapping dimeric assembly

scientific article

Structural basis for the carbohydrate recognition of the Sclerotium rolfsii lectin

scientific article

Structure based inhibitor design targeting glycogen phosphorylase B. Virtual screening, synthesis, biochemical and biological assessment of novel N-acyl-β-d-glucopyranosylamines

scientific article

Studies on the essential intramolecular interaction between the A1 and A2 domains of von Willebrand factor

scientific article published on 01 February 2013

Sulphate activates phosphorylase b by binding to the Ser (P) site

scientific article published on 01 January 1991

Sulphate-activated phosphorylase b: the pH-dependence of catalytic activity

scientific article published on September 1995

Synthetic flavonoid derivatives targeting the glycogen phosphorylase inhibitor site: QM/MM-PBSA motivated synthesis of substituted 5,7-dihydroxyflavones, crystallography, in vitro kinetics and ex-vivo cellular experiments reveal novel potent inhibit

scientific article published on 10 June 2020

Synthetic, enzyme kinetic, and protein crystallographic studies of C-β-d-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase

scientific article

The ammonium sulfate activation of phosphorylase b

scientific article published on 01 February 1990

The ammonium sulfate inhibition of human angiogenin

scientific article

The architecture of hydrogen and sulfur σ-hole interactions explain differences in the inhibitory potency of C-β-d-glucopyranosyl thiazoles, imidazoles and an N-β-d glucopyranosyl tetrazole for human liver glycogen phosphorylase and offer new insigh

scientific article published on 14 November 2019

The binding of 3'-N-piperidine-4-carboxyl-3'-deoxy-ara-uridine to ribonuclease A in the crystal

scientific article published on 30 May 2006

The binding of C5-alkynyl and alkylfurano[2,3-d]pyrimidine glucopyranonucleosides to glycogen phosphorylase b: synthesis, biochemical and biological assessment

scientific article

The binding of IMP to ribonuclease A.

scientific article published in August 2005

The binding of β- and γ-cyclodextrins to glycogen phosphorylase b: Kinetic and crystallographic studies

scientific article

The binding of β-d-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: A new class of inhibitors

scientific article

The crystal structure of human placenta growth factor-1 (PlGF-1), an angiogenic protein, at 2.0 A resolution

scientific article

The structure of glycogen phosphorylase b with an alkyldihydropyridine-dicarboxylic acid compound, a novel and potent inhibitor

scientific article

The σ-hole phenomenon of halogen atoms forms the structural basis of the strong inhibitory potency of C5 halogen substituted glucopyranosyl nucleosides towards glycogen phosphorylase b

scientific article

Toward rational design of ribonuclease inhibitors: high-resolution crystal structure of a ribonuclease A complex with a potent 3',5'-pyrophosphate-linked dinucleotide inhibitor

scientific article

Triazole double-headed ribonucleosides as inhibitors of eosinophil derived neurotoxin

scientific article

Triazole pyrimidine nucleosides as inhibitors of Ribonuclease A. Synthesis, biochemical, and structural evaluation

scientific article

hCINAP is an atypical mammalian nuclear adenylate kinase with an ATPase motif: Structural and functional studies

scientific article

van der Waals interactions govern C-β-d-glucopyranosyl triazoles' nM inhibitory potency in human liver glycogen phosphorylase.

scientific article published on 5 May 2017

List of works by Demetres D. Leonidas

1-(3-Deoxy-3-fluoro-beta-d-glucopyranosyl) pyrimidine derivatives as inhibitors of glycogen phosphorylase b: Kinetic, crystallographic and modelling studies

3'-axial CH2 OH substitution on glucopyranose does not increase glycogen phosphorylase inhibitory potency. QM/MM-PBSA calculations suggest why

A multidisciplinary study of 3-(β-d-glucopyranosyl)-5-substituted-1,2,4-triazole derivatives as glycogen phosphorylase inhibitors: Computation, synthesis, crystallography and kinetics reveal new potent inhibitors.

Affinity crystallography reveals binding of pomegranate juice anthocyanins at the inhibitor site of glycogen phosphorylase: the contribution of sugar moiety to potency and its implications to binding mode

Affinity crystallography reveals the bioactive compounds of industrial juicing byproducts of Punica granatum for glycogen phosphorylase.

Amide-1,2,3-triazole bioisosterism: the glycogen phosphorylase case

An evaluation of indirubin analogues as phosphorylase kinase inhibitors.

Anopheles gambiae odorant binding protein crystal complex with the synthetic repellent DEET: implications for structure-based design of novel mosquito repellents

AtHESPERIN: a novel regulator of circadian rhythms with poly(A)-degrading activity in plants.

Binding of N-acetyl-N '-beta-D-glucopyranosyl urea and N-benzoyl-N '-beta-D-glucopyranosyl urea to glycogen phosphorylase b: kinetic and crystallographic studies

Binding of beta-D-glucopyranosyl bismethoxyphosphoramidate to glycogen phosphorylase b: kinetic and crystallographic studies

Binding of oxalyl derivatives of beta-d-glucopyranosylamine to muscle glycogen phosphorylase b.

Binding of phosphate and pyrophosphate ions at the active site of human angiogenin as revealed by X-ray crystallography

Binding of the potential antitumour agent indirubin-5-sulphonate at the inhibitor site of rabbit muscle glycogen phosphorylase b. Comparison with ligand binding to pCDK2-cyclin A complex

Binding ofN-acetyl-N ′-β-d-glucopyranosyl urea andN-benzoyl-N ′-β-d-glucopyranosyl urea to glycogen phosphorylaseb

Bioactivity of glycogen phosphorylase inhibitors that bind to the purine nucleoside site

Biochemical and biological assessment of the inhibitory potency of extracts from vinification byproducts of Vitis vinifera extracts against glycogen phosphorylase

Biochemical and in silico identification of the active site and the catalytic mechanism of the circadian deadenylase HESPERIN

Charcot-Leyden crystal protein (galectin-10) is not a dual function galectin with lysophospholipase activity but binds a lysophospholipase inhibitor in a novel structural fashion

Cleavage of 3',5'-pyrophosphate-linked dinucleotides by ribonuclease A and angiogenin

Computation as a tool for glycogen phosphorylase inhibitor design

Control of phosphorylase b conformation by a modified cofactor: crystallographic studies on R-state glycogen phosphorylase reconstituted with pyridoxal 5'-diphosphate ⬇️

Crystal structure of eosinophil cationic protein at 2.4 A resolution

Crystal structure of human Charcot-Leyden crystal protein, an eosinophil lysophospholipase, identifies it as a new member of the carbohydrate-binding family of galectins

Crystal structure of rabbit muscle glycogen phosphorylase a in complex with a potential hypoglycaemic drug at 2.0 A resolution

Crystal structures of ribonuclease A complexes with 5'-diphosphoadenosine 3'-phosphate and 5'-diphosphoadenosine 2'-phosphate at 1.7 A resolution

Crystallization and preliminary X-ray crystallographic analysis ofSclerotium rolfsiilectin

Crystallization and preliminary investigations on a telomeric repeat sequence C4A2C4A2.

Crystallographic and computational studies on 4-phenyl-N-(beta-D-glucopyranosyl)-1H-1,2,3-triazole-1-acetamide, an inhibitor of glycogen phosphorylase: comparison with alpha-D-glucose, N-acetyl-beta-D-glucopyranosylamine and [...]

Crystallographic studies on N-azidoacetyl-β-d-glucopyranosylamine, an inhibitor of glycogen phosphorylase: Comparison with N-acetyl-β-d-glucopyranosylamine

Crystallographic studies on acyl ureas, a new class of glycogen phosphorylase inhibitors, as potential antidiabetic drugs.

Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency

Crystallographic studies on two bioisosteric analogues, N-acetyl-beta-D-glucopyranosylamine and N-trifluoroacetyl-beta-D-glucopyranosylamine, potent inhibitors of muscle glycogen phosphorylase

Design of inhibitors of glycogen phosphorylase: a study of alpha- and beta-C-glucosides and 1-thio-beta-D-glucose compounds

Editorial: Role of Ribonucleases in Immune Response Regulation During Infection and Cancer

Evidence for novel action at the cell binding site of human Angiogenin revealed by heteronuclear NMR spectroscopy, in silico and in vivo studies.

FR258900, a potential anti-hyperglycemic drug, binds at the allosteric site of glycogen phosphorylase

Glucopyranosylidene-spiro-imidazolinones, a New Ring System: Synthesis and Evaluation as Glycogen Phosphorylase Inhibitors by Enzyme Kinetics and X-ray Crystallography

Glucopyranosylidene-spiro-iminothiazolidinone, a new bicyclic ring system: synthesis, derivatization, and evaluation for inhibition of glycogen phosphorylase by enzyme kinetic and crystallographic methods

Glucose-based spiro-isoxazolines: a new family of potent glycogen phosphorylase inhibitors

Glycogen phosphorylase as a target for type 2 diabetes: synthetic, biochemical, structural and computational evaluation of novel N-acyl-N´-(β-D-glucopyranosyl) urea inhibitors

Guest-host crosstalk in an angiogenin-RNase A chimeric protein

Halogen-substituted (C-β-D-glucopyranosyl)-hydroquinone regioisomers: synthesis, enzymatic evaluation and their binding to glycogen phosphorylase

High Consistency of Structure-Based Design and X-Ray Crystallography: Design, Synthesis, Kinetic Evaluation and Crystallographic Binding Mode Determination of Biphenyl--acyl-β-d-Glucopyranosylamines as Glycogen Phosphorylase Inhibitors

High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors

Iminosugars as potential inhibitors of glycogenolysis: structural insights into the molecular basis of glycogen phosphorylase inhibition

In the Search of Glycogen Phosphorylase Inhibitors: Synthesis of C-D-Glycopyranosylbenzo(hydro)quinones – Inhibition of and Binding to Glycogen Phosphorylase in the Crystal

Indirubin-3-Aminooxy-Acetate Inhibits Glycogen Phosphorylase by Binding at the Inhibitor and the Allosteric Site. Broad Specificities of the Two Sites

Influence of naturally-occurring 5â ²-pyrophosphate-linked substituents on the binding of adenylic inhibitors to ribonuclease a: An X-ray crystallographic study

Inhibition of rabbit muscle glycogen phosphorylase by D-gluconohydroximo-1,5-lactone-N-phenylurethane

Inhibitor design for ribonuclease A: the binding of two 5'-phosphate uridine analogues.

Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1, 3, 4-oxadiazole, -benzothiazole, and -benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site.

Kinetic properties of tetrameric glycogen phosphorylase b in solution and in the crystalline state ⬇️

Mapping the ribonucleolytic active site of bovine seminal ribonuclease. The binding of pyrimidinyl phosphonucleotide inhibitors

Molecular Cloning, Carbohydrate Specificity and the Crystal Structure of Two Sclerotium rolfsii Lectin Variants

Morpholino, piperidino, and pyrrolidino derivatives of pyrimidine nucleosides as inhibitors of ribonuclease A: synthesis, biochemical, and crystallographic evaluation

N-(4-Substituted-benzoyl)-N′-(β-d-glucopyranosyl)ureas as inhibitors of glycogen phosphorylase: Synthesis and evaluation by kinetic, crystallographic, and molecular modelling methods

NMR study of Met-1 human Angiogenin: (1)H, (13)C, (15)N backbone and side-chain resonance assignment

Nanomolar Inhibitors of Glycogen Phosphorylase Based on β-d-Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography Study

Natural flavonoids as antidiabetic agents. The binding of gallic and ellagic acids to glycogen phosphorylase b

Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies

New inhibitors of glycogen phosphorylase as potential antidiabetic agents.

Nicotinic Cholinergic System and COVID-19: In Silico Identification of an Interaction between SARS-CoV-2 and Nicotinic Receptors with Potential Therapeutic Targeting Implications

Nicotinic cholinergic system and COVID-19: <i>In silico</i> evaluation of nicotinic acetylcholine receptor agonists as potential therapeutic interventions

Oxidation of human serum albumin exhibits inter-individual variability after an ultra-marathon mountain race

Phytogenic Polyphenols as Glycogen Phosphorylase Inhibitors: The Potential of Triterpenes and Flavonoids for Glycaemic Control in Type 2 Diabetes.

Potential interference of aluminum chlorohydrate with estrogen receptor signaling in breast cancer cells.

Probing the β-pocket of the active site of human liver glycogen phosphorylase with 3-(C-β-d-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors.

Proteomic analysis of human Angiogenin interactions reveals cytoplasmic PCNA as a putative binding partner

Recognition of ribonuclease A by 3'-5'-pyrophosphate-linked dinucleotide inhibitors: a molecular dynamics/continuum electrostatics analysis.

Selective Recognition of Mannose by the Human Eosinophil Charcot-Leyden Crystal Protein (Galectin-10): A Crystallographic Study at 1.8 Å Resolution

Sourcing the affinity of flavonoids for the glycogen phosphorylase inhibitor site via crystallography, kinetics and QM/MM-PBSA binding studies: comparison of chrysin and flavopiridol

Structural Basis for the Recognition of Carbohydrates by Human Galectin-7, ⬇️

Structural analysis of the Rhizoctonia solani agglutinin reveals a domain-swapping dimeric assembly

Structural basis for the carbohydrate recognition of the Sclerotium rolfsii lectin

Structure based inhibitor design targeting glycogen phosphorylase B. Virtual screening, synthesis, biochemical and biological assessment of novel N-acyl-β-d-glucopyranosylamines

Studies on the essential intramolecular interaction between the A1 and A2 domains of von Willebrand factor

Sulphate activates phosphorylase b by binding to the Ser (P) site

Sulphate-activated phosphorylase b: the pH-dependence of catalytic activity