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List of works by Jonathan Charles Howard

A Toxoplasma gondii Pseudokinase Inhibits Host IRG Resistance Proteins ⬇️

scientific article published on July 10, 2012

A dedicated promoter drives constitutive expression of the cell-autonomous immune resistance GTPase, Irga6 (IIGP1) in mouse liver

scientific article

An analysis of the antigen binding site of RT1.Aa suggests an allele-specific motif

scientific article published on 01 January 1995

Analysis of lymphocytes reactive to histocompatibility antigens. II. Exponential alloantigen-dependent lymphocyte growth in vitro

scientific article published on March 15, 1979

Antibodies to major histocompatibility antigens produced by hybrid cell lines

scientific article published in Nature

Antibody density on rat red cells determines the rate of activation of the complement component C1

scientific article published on 01 October 1985

Antigen recognition

scientific article published on 01 February 1997

Antigen recognition

scientific article published on 01 February 1999

Antimicrobial effects of murine mesenchymal stromal cells directed against Toxoplasma gondii and Neospora caninum: role of immunity-related GTPases (IRGs) and guanylate-binding proteins (GBPs)

scientific article published on 27 December 2012

Author Correction: Molecular mechanism for the control of virulent Toxoplasma gondii infections in wild-derived mice

scientific article published on 04 April 2019

Balance of Irgm protein activities determines IFN-gamma-induced host defense

scientific article published on 27 January 2009

Brucella abortus induces Irgm3 and Irga6 expression via type-I IFN by a MyD88-dependent pathway, without the requirement of TLR2, TLR4, TLR5 and TLR9.

scientific article published on 9 September 2009

C1 activation by immunoglobulin and immunoglobulin antibodies

scientific article published on 01 October 1984

Cellular responses to interferon-gamma

scientific article (publication date: 1997)

Chimeric drift in blood cell populations of chimeric rats constructed between congenic strains

scientific article published on 01 January 1993

Cim: an MHC class II-linked allelism affecting the antigenicity of a classical class I molecule for T lymphocytes

scientific article published on 01 January 1991

Cloning and expression of class I major histocompatibility complex genes of the rat ⬇️

scientific article published on June 1, 1992

Collaboration between thymus-derived and marrow-derived thoracic duct lymphocytes in the hemolysin response of the rat

scientific article published on 01 March 1972

Comparative genomics of the apicomplexan parasites Toxoplasma gondii and Neospora caninum: Coccidia differing in host range and transmission strategy

scientific article published in 2012

Complement-dependent synergistic effects of rat monoclonal IgG antibodies in vivo

scientific article published on 01 February 1993

Concerted evolution of class I genes in the major histocompatibility complex of murine rodents.

scientific article published on March 1990

Death and resurrection of the human IRGM gene

scientific article published in March 2009

Demonstration of MHC-specific haemolytic plaque-forming cells ⬇️

scientific article published on March 29, 1979

Differential inductions of TNF-alpha and IGTP, IIGP by structurally diverse classic and non-classic lipopolysaccharides

scientific article published on March 2006

Disruption of Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases.

scientific article

Disruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death

scientific article

First class way to develop a brain

scientific article published in November 1998

IIGP1, an Interferon-γ-inducible 47-kDa GTPase of the Mouse, Showing Cooperative Enzymatic Activity and GTP-dependent Multimerization ⬇️

scientific article published on May 5, 2003

Identification of marrow-derived and thymus-derived small lymphocytes in the lymphoid tissue and thoracic duct lymph of normal rats.

scientific article

Identification of the microsporidian Encephalitozoon cuniculi as a new target of the IFNγ-inducible IRG resistance system

scientific article

Immunity-related GTPase M (IRGM) proteins influence the localization of guanylate-binding protein 2 (GBP2) by modulating macroautophagy

scientific article published on 12 July 2011

Immunoglobulin heavy chain locus of the rat: striking homology to mouse antibody genes

scientific article

Immunological help at last.

scientific article published in April 1985

Inactive and active states of the interferon-inducible resistance GTPase, Irga6, in vivo

scientific journal article

Innate resistance against Toxoplasma gondii: an evolutionary tale of mice, cats, and men.

scientific article published on February 2014

Introduction: cell-autonomous immunity

scientific article published on 11 September 2007

Irgm1 (LRG-47), a Regulator of Cell-Autonomous Immunity, Does Not Localize to Mycobacterial or Listerial Phagosomes in IFN-γ–Induced Mouse Cells ⬇️

scientific article published on July 10, 2013

Is a mutator analogous to the Ig hypermutator of the sheep ileal Peyer's patch active on MHC class I genes in the germ line?

scientific article published on 01 May 2000

Isolation of a functional cDNA encoding the RT1.Au MHC class I heavy chain by a novel PCR-based method

scientific article published in January 1995

James L. Gowans 1924-2020

scientific article published on 01 June 2020

Localisation and mislocalisation of the interferon-inducible immunity-related GTPase, Irgm1 (LRG-47) in mouse cells

scientific article

Loss of the interferon-γ-inducible regulatory immunity-related GTPase (IRG), Irgm1, causes activation of effector IRG proteins on lysosomes, damaging lysosomal function and predicting the dramatic susceptibility of Irgm1-deficient mice to infection.

scientific article

MHC restriction, self-tolerance and the thymus

scientific article published on 01 July 1980

Markers for interspecies relationship in the RT1 complex

scientific article published on 01 May 1997

Membrane recycling and antigen presentation

scientific article published on 01 June 1986

Modeling infectious disease in mice: co-adaptation and the role of host-specific IFNgamma responses

scientific article

Molecular mechanism for the control of virulent Toxoplasma gondii infections in wild-derived mice

scientific article published on 15 March 2019

Monoclonal Antibodies as Tools to Analyze the Serological and Genetic Complexities of Major Transplantation Antigens ⬇️

scientific article published on January 1, 1979

Not all converted yet ⬇️

scientific article published on 01 August 1995

Phosphorylation of Mouse Immunity-Related GTPase (IRG) Resistance Proteins Is an Evasion Strategy for Virulent Toxoplasma gondii ⬇️

scientific article published on December 21, 2010

RabGDIα is a negative regulator of interferon-γ-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii

scientific article

Rat RT1 orthologs of mouse H2-M class Ib genes

scientific article published in January 1995

Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii

scientific journal article

Restrictions on the use of antigenic peptides by the immune system

scientific article

Specific positive selection of lymphocytes reactive to strong histocompatibility antigens.

scientific article published on September 1974

Spontaneous focal activation of invariant natural killer T (iNKT) cells in mouse liver and kidney

scientific article

Targeting behavior of rat monoclonal IgG antibodies in vivo: role of antibody isotype, specificity and the target cell antigen density

scientific article published on 01 April 1991

The IFN-γ-inducible GTPase, Irga6, protects mice against Toxoplasma gondii but not against Plasmodium berghei and some other intracellular pathogens

scientific article

The IRG protein-based resistance mechanism in mice and its relation to virulence in Toxoplasma gondii

scientific article published on 23 July 2011

The IRG proteins: a function in search of a mechanism

scientific article published on 31 December 2007

The Toxoplasma gondii rhoptry protein ROP18 is an Irga6-specific kinase and regulated by the dense granule protein GRA7.

scientific article published on 06 August 2015

The activation mechanism of Irga6, an interferon-inducible GTPase contributing to mouse resistance against Toxoplasma gondii

scientific article

The alloantigenic organization of RT1Aa, a class I major histocompatibility complex molecule of the rat

scientific article published on 01 May 1984

The arginine-rich N-terminal domain of ROP18 is necessary for vacuole targeting and virulence of Toxoplasma gondii

scientific article published on 20 September 2012

The immunity-related GTPase Irga6 dimerizes in a parallel head-to-head fashion

scientific article

The immunity-related GTPases in mammals: a fast-evolving cell-autonomous resistance system against intracellular pathogens

scientific article

The impact of Toxoplasma gondii on the mammalian genome

scientific article

The interferon-inducible GTPases.

scientific article published on January 2006

The mechanism of graft rejection and the concept of antigenic strength

scientific article published on 01 December 1981

The mechanism of synergistic complement-mediated lysis of rat red cells by monoclonal IgG antibodies

scientific article published on 01 August 1983

The mouse resistance protein Irgm1 (LRG-47): a regulator or an effector of pathogen defense?

scientific article

The rat cim effect: TAP allele-dependent changes in a class I MHC anchor motif and evidence against C-terminal trimming of peptides in the ER

scientific article published on 01 February 1996

The role of subregions of the rat major histocompatibility complex in the rejection and passive enhancement of renal allografts ⬇️

scientific article published on January 1, 1979

Tumorigenicity conferred to lymphoma mutant by major histocompatibility complex-encoded transporter gene.

scientific article

UNC93B1 mediates host resistance to infection with Toxoplasma gondii

scientific article

Virulent Toxoplasma gondii evade immunity-related GTPase-mediated parasite vacuole disruption within primed macrophages

scientific article

Why didn't Darwin discover Mendel's laws?

scientific article published on 24 February 2009

Xenogeneic responses in vitro in the Syrian hamster, Mesocricetus auratus. I. Evidence for a normal T cell repertoire

scientific article published on 01 January 1991

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