Loss of the interferon-γ-inducible regulatory immunity-related GTPase (IRG), Irgm1, causes activation of effector IRG proteins on lysosomes, damaging lysosomal function and predicting the dramatic susceptibility of Irgm1-deficient mice to infection.
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| Description | scientific article |
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author: Jonathan Charles Howard |
| Publication date | April 20, 2016 |
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