List of works by Laura Herrero

(-)-UB006: A new fatty acid synthase inhibitor and cytotoxic agent without anorexic side effects.

scientific article

Adenovirus-mediated overexpression of liver carnitine palmitoyltransferase I in INS1E cells: effects on cell metabolism and insulin secretion

scientific journal article

Alteration of the malonyl-CoA/carnitine palmitoyltransferase I interaction in the beta-cell impairs glucose-induced insulin secretion.

scientific article published on February 2005

Altered circadian rhythm and metabolic gene profile in rats subjected to advanced light phase shifts

scientific article published on 2 April 2015

Brown Adipose Tissue Bioenergetics: A New Methodological Approach

scientific article

C75 is converted to C75-CoA in the hypothalamus, where it inhibits carnitine palmitoyltransferase 1 and decreases food intake and body weight

scientific article

CPT I overexpression protects L6E9 muscle cells from fatty acid-induced insulin resistance

scientific article published on 24 October 2006

CPT1C in the ventromedial nucleus of the hypothalamus is necessary for brown fat thermogenesis activation in obesity.

scientific article

Carnitine Palmitoyltransferase 1 Increases Lipolysis, UCP1 Protein Expression and Mitochondrial Activity in Brown Adipocytes

scientific article

Carnitine palmitoyltransferase 1C: From cognition to cancer.

scientific article published on 17 December 2015

Ceramide levels regulated by carnitine palmitoyltransferase 1C control dendritic spine maturation and cognition

scientific article

Ceramides and mitochondrial fatty acid oxidation in obesity.

scientific article

Differential pharmacologic properties of the two C75 enantiomers: (+)-C75 is a strong anorectic drug; (-)-C75 has antitumor activity

scientific article published on May 2013

Enhanced fatty acid oxidation in adipocytes and macrophages reduces lipid-induced triglyceride accumulation and inflammation.

scientific article published on 24 February 2015

Enhancing hepatic fatty acid oxidation as a strategy for reversing metabolic disorders programmed by maternal undernutrition during gestation.

scientific article published on 14 May 2014

Essential role of Nrf2 in the protective effect of lipoic acid against lipoapoptosis in hepatocytes

scientific article

Fatty acid metabolism and the basis of brown adipose tissue function

scientific article

Ghrelin Causes a Decline in GABA Release by Reducing Fatty Acid Oxidation in Cortex.

scientific article

HIF drives lipid deposition and cancer in ccRCC via repression of fatty acid metabolism

scientific article published on 24 November 2017

Hypothalamic regulation of liver and muscle nutrient partitioning by brain-specific carnitine palmitoyltransferase 1C (CPT1C) in male mice.

scientific article published on 3 May 2017

Impact of Adaptive Thermogenesis in Mice on the Treatment of Obesity

scientific article published on 28 January 2020

Increased inflammation, oxidative stress and mitochondrial respiration in brown adipose tissue from obese mice

scientific article published on 22 November 2017

Inflammation and adipose tissue macrophages in lipodystrophic mice

scientific article

Long-term increased carnitine palmitoyltransferase 1A expression in ventromedial hypotalamus causes hyperphagia and alters the hypothalamic lipidomic profile

scientific article

Mitochondrial fatty acid oxidation in obesity

scientific article

Molecular therapy for obesity and diabetes based on a long-term increase in hepatic fatty-acid oxidation

scientific article published on 11 February 2011

New approaches targeting brown adipose tissue transplantation as a therapy in obesity

scientific article published on 19 July 2018

Novel effect of C75 on carnitine palmitoyltransferase I activity and palmitate oxidation

scientific article

Obesity, Inflammation, and Insulin Resistance

scientific article

Rapamycin negatively impacts insulin signaling, glucose uptake and uncoupling protein-1 in brown adipocytes

scientific article

Renal tubule Cpt1a overexpression protects from kidney fibrosis by restoring mitochondrial homeostasis

scientific article published in March 2021

Short-term vitamin E treatment impairs reactive oxygen species signaling required for adipose tissue expansion, resulting in fatty liver and insulin resistance in obese mice

scientific article published on 13 October 2017

Targeting AgRP neurons to maintain energy balance: Lessons from animal models

scientific article published on 18 July 2018

The transcription factor SREBP-1c is instrumental in the development of beta-cell dysfunction

scientific article published on 24 February 2003

Vitamin E reduces adipose tissue fibrosis, inflammation, and oxidative stress and improves metabolic profile in obesity

scientific article published on 06 July 2015