List of works - Matthias Nauck

1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

scientific article

A SULT2A1 genetic variant identified by GWAS as associated with low serum DHEAS does not impact on the actual DHEA/DHEAS ratio

scientific article (publication date: February 2013)

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A descriptive analysis of relations between parents' self-reported smoking behavior and infants' daily exposure to environmental tobacco smoke

scientific article published on 19 July 2010

A genome-wide association study identifies novel loci associated with circulating IGF-I and IGFBP-3

scientific article

A genome-wide association study identifies three loci associated with mean platelet volume

scientific article published on 24 December 2008

A genome-wide association study of metabolic traits in human urine

scientific article

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

scientific article

A mega-analysis of genome-wide association studies for major depressive disorder

scientific article

A network-based approach to visualize prevalence and progression of metabolic syndrome components

scientific article

A reference panel of 64,976 haplotypes for genotype imputation

scientific article

Analysis of shared heritability in common disorders of the brain

scientific article published on 21 June 2018

Analyzing illumina gene expression microarray data from different tissues: methodological aspects of data analysis in the metaxpress consortium

scientific article

Association Between Serum Testosterone and Sex Hormone-Binding Globulin and Exercise Capacity in Men: Results of the Study of Health in Pomerania (SHIP)

article

Association between Serum Insulin-Like Growth Factor-I Levels and Thyroid Disorders in a Population-Based Study

scientific article published on 31 July 2007

Association between glycemia, serum lipoproteins, and the risk of oral leukoplakia: the population-based Study of Health in Pomerania (SHIP)

scientific article

Association between serum insulin-like growth factor I or IGF-binding protein 3 and estimated glomerular filtration rate: results of a population-based sample

scientific article

Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

scholarly article by Miruna C. Barbu et al published July 2018 in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

Association of alcohol consumption with allergic disease and asthma: a multi-centre Mendelian randomization analysis

scientific article published on 30 October 2018

Association of sex hormones with incident 10-year cardiovascular disease and mortality in women

scientific article published on 28 August 2015

Association of testosterone levels with endothelial function in men: results from a population-based study.

scientific article published on 17 November 2011

Associations between thyroid hormones and serum metabolite profiles in an euthyroid population

scientific article

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

article

Associations of androgens with depressive symptoms and cognitive status in the general population

scientific article

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Associations of genetic determinants of serum vitamin B12 and folate concentrations with hay fever and asthma: a Mendelian randomization meta-analysis.

scientific article

Associations of trauma exposure and post-traumatic stress disorder with the activity of the renin–angiotensin–aldosterone-system in the general population

scientific article published on 18 June 2018

Blood cis-eQTL analysis fails to identify novel association signals among sub-threshold candidates from genome-wide association studies in restless legs syndrome

scientific article

Causal relationship between obesity and serum testosterone status in men: A bi-directional mendelian randomization analysis

scientific article

Changes of myocardial gene expression and protein composition in patients with dilated cardiomyopathy after immunoadsorption with subsequent immunoglobulin substitution

scientific article published on 13 July 2016

Clinical correlates of sex hormones in women: The study of health in Pomerania

scientific article published on 26 May 2016

Cohort Profile: The Study of Health in Pomerania

article

Cohort profile: Greifswald approach to individualized medicine (GANI_MED)

scientific article

Common Genetic Variation in Relation to Brachial Vascular Dimensions and Flow-Mediated Vasodilation

scientific article published on 01 February 2019

Common genetic variants influence human subcortical brain structures

scientific article

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways ⬇️

scientific article

Common variants in Mendelian kidney disease genes and their association with renal function

scientific article published on 12 September 2013

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 23 August 2017

Corrigendum: 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

scientific article published on 26 May 2017

Corrigendum: Polygenic Architecture of Human Neuroanatomical Diversity

scientific article published on 06 April 2020

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome

scientific article published in 2021

Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking

scientific article

Do patients with type 1 and type 2 diabetes really have an impaired endothelial function? A population-based propensity score matching analysis

scientific article

Endogenous Androgens and Sex Hormone-Binding Globulin in Women and Risk of Metabolic Syndrome and Type 2 Diabetes

scientific article

Estimated daily salt intake in relation to blood pressure and blood lipids: the role of obesity.

scientific article published on 3 October 2014

Evidence for Stress-like Alterations in the HPA-Axis in Women Taking Oral Contraceptives

scientific article published on 26 October 2017

Exome Chip Analysis Identifies Low-Frequency a on Brain Magnetic Imaging

Extensive alterations of the whole-blood transcriptome are associated with body mass index: results of an mRNA profiling study involving two large population-based cohorts

scientific article published on 15 October 2015

Gender-specific pathway differences in the human serum metabolome

scientific article

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

scholarly article published 28 August 2017

Genetic architecture of subcortical brain structures in 38,851 individuals

scientific article published on 21 October 2019

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

scientific article

Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium

scientific article

Genetic determinants of serum testosterone concentrations in men.

scientific article

Genetic evidence for a role of adiponutrin in the metabolism of apolipoprotein B-containing lipoproteins

scientific article published on 03 September 2009

Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans

scientific article published on 20 January 2020

Genetics of osteopontin in patients with chronic kidney disease: The German Chronic Kidney Disease study

scientific article published on 06 April 2022

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

scientific article published in November 2018

Genome-Wide Association Study Identifies Variants Associated With Autoimmune Hepatitis Type 1

article

Genome-Wide Association Study with Targeted and Non-targeted NMR Metabolomics Identifies 15 Novel Loci of Urinary Human Metabolic Individuality

scientific article published on 9 September 2015

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

scientific article published in February 2013

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

scientific article published on 26 April 2018

Genome-wide association and functional follow-up reveals new loci for kidney function

scientific article

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

scientific article published on 11 September 2019

Genome-wide association study identifies four genetic loci associated with thyroid volume and goiter risk ⬇️

scientific article

Genome-wide association study of 1,5-anhydroglucitol identifies novel genetic loci linked to glucose metabolism

scientific article

Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume

scientific article published in Nature Communications

Genome-wide association study of chronic periodontitis in a general German population

scientific journal article

Genome-wide gene-environment interaction in depression: A systematic evaluation of candidate genes: The childhood trauma working-group of PGC-MDD.

scientific article published on 21 November 2017

Genome-wide meta-analyses of plasma renin activity and concentration reveal association with the kininogen 1 and prekallikrein genes

scientific article

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

scientific article

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 27 April 2017

Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits ⬇️

scientific article published on 21 June 2016

Health-related quality of life and IGF-1 in GH-deficient adult patients on GH replacement therapy: analysis of the German KIMS data and the Study of Health in Pomerania

scientific article

Hemofiltration of recombinant hirudin by different hemodialyzer membranes: implications for clinical use.

scientific article

Identification of common variants associated with human hippocampal and intracranial volumes

scientific article published on 15 April 2012

Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease

scientific article

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

scientific article published on 12 September 2017

Impact of common regulatory single-nucleotide variants on gene expression profiles in whole blood

scientific article

Impaired Exocrine Pancreatic Function Associates With Changes in Intestinal Microbiota Composition and Diversity

article

Incidence of all-cause and cardiovascular mortality predicted by symmetric dimethylarginine in the population-based study of health in pomerania

scientific article

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

scientific article

Incremental effects of endocrine and metabolic biomarkers and abdominal obesity on cardiovascular mortality prediction

scientific article (publication date: 2012)

Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function

scientific article published on 8 September 2012

Investigating the causal effect of smoking on hay fever and asthma: a Mendelian randomization meta-analysis in the CARTA consortium

scientific article

KCND3 potassium channel gene variant confers susceptibility to electrocardiographic early repolarization pattern

scientific article published on 05 December 2019

Long-term instability of the intestinal microbiome is associated with metabolic liver disease, low microbiota diversity, diabetes mellitus and impaired exocrine pancreatic function

scientific article published on 09 November 2020

Low Serum Testosterone Is Associated with Increased Mortality in Men with Stage 3 or Greater Nephropathy

scientific article published on 18 February 2011

Low testosterone concentrations in men contribute to the gender gap in cardiovascular morbidity and mortality.

scientific article published on 20 November 2012

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations

scientific article published in June 2009

Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium

scientific article published on 11 September 2015

Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder

scientific article

Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations

scientific article

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

scientific article

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

scientific article published on 07 January 2019

Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline

scientific article published on 30 October 2020

Metabolic Fingerprints of Circulating IGF-1 and the IGF-1/IGFBP-3 Ratio: A Multifluid Metabolomics Study

scientific article

Methods for measurement of LDL-cholesterol: a critical assessment of direct measurement by homogeneous assays versus calculation

scientific article

Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus

scientific article

Mitochondrial DNA variants in obesity

scientific article

Modulation of genetic associations with serum urate levels by body-mass-index in humans

scientific article

Mortality and serum insulin-like growth factor (IGF)-I and IGF binding protein 3 concentrations.

scientific article published on 17 February 2009

Mortality is associated with inflammation, anemia, specific diseases and treatments, and molecular markers

scientific article

Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

article

Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI

scientific article published on 7 February 2015

Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation

scientific article published on 05 December 2016

Multiple loci are associated with white blood cell phenotypes

scientific article

Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium

scientific article

New gene functions in megakaryopoiesis and platelet formation

scientific article published on 30 November 2011

New loci associated with kidney function and chronic kidney disease

scientific article

Novel genetic loci associated with hippocampal volume

scientific article published on 18 January 2017

Novel genetic loci underlying human intracranial volume identified through genome-wide association

scientific article (publication date: 3 October 2016)

Periodontal status and A1C change: longitudinal results from the study of health in Pomerania (SHIP).

scientific article

Phenotype-driven identification of modules in a hierarchical map of multifluid metabolic correlations

scientific article published on 21 September 2017

Plasma Fibroblast Growth Factor 23: Clinical Correlates and Association With Cardiovascular Disease and Mortality in the Framingham Heart Study

scientific article published on 06 July 2016

Polygenic Architecture of Human Neuroanatomical Diversity

scientific article published on 28 February 2020

Positive association between testosterone, blood pressure, and hypertension in women: longitudinal findings from the Study of Health in Pomerania.

scientific article published in June 2013

Positive association of serum prolactin concentrations with all-cause and cardiovascular mortality

article

Prediction of improvement in quality of life (QoL-AGHDA) in adults with growth hormone deficiency by normative reference limits: data of the German KIMS cohort

scientific article published on August 23, 2011

Prevalence of hypopituitarism after intracranial operations not directly associated with the pituitary gland

scientific article

Prospective association of low total testosterone concentrations with an adverse lipid profile and increased incident dyslipidemia.

scientific article published in February 2011

Prospective inverse associations of sex hormone concentrations in men with biomarkers of inflammation and oxidative stress.

scientific article published on 29 December 2011

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Rare and low-frequency coding variants in CXCR2 and other genes are associated with hematological traits

scientific article (publication date: June 2014)

Reference intervals for serum osteocalcin concentrations in adult men and women from the study of health in Pomerania ⬇️

scientific article published on March 13, 2013

Regional differences of undiagnosed type 2 diabetes and prediabetes prevalence are not explained by known risk factors

scientific article

SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function

scientific article published on 5 December 2016

Self-perceived quality of life predicts mortality risk better than a multi-biomarker panel, but the combination of both does best

scientific article (publication date: 12 July 2011)

Serum androgen concentrations and subclinical measures of cardiovascular disease in men and women

scientific article

Serum prolactin concentrations as risk factor of metabolic syndrome or type 2 diabetes?

scientific article

Seventy-five genetic loci influencing the human red blood cell

scientific article published on 5 December 2012

Sex Hormones and Sleep in Men and Women From the General Population: A Cross-Sectional Observational Study

scientific article published on 12 July 2016

Sex-specific metabolic profiles of androgens and its main binding protein SHBG in a middle aged population without diabetes

scientific article

Storage of thawed plasma for a liquid plasma bank: impact of temperature and methylene blue pathogen inactivation

scientific article

Systematic identification of trans eQTLs as putative drivers of known disease associations

scientific article (publication date: October 2013)

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

scientific article published on 02 October 2019

The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

scientific article

The Predictive Value of Different Measures of Obesity for Incident Cardiovascular Events and Mortality

scientific article

The association of serum testosterone levels and ventricular repolarization

scientific article

The genetic architecture of the human cerebral cortex

scientific article

The inverse link between genetic risk for schizophrenia and migraine through NMDA (N-methyl-D-aspartate) receptor activation via D-serine

scientific article published on 6 July 2016

The relationship between cortisol awakening response and trait resilience in two patient cohorts and one population-based cohort

scientific article published in 2022

The severity of trauma determines the immune response to PF4/heparin and the frequency of heparin-induced thrombocytopenia

scientific article

Thyroid function tests in patients taking thyroid medication in Germany: Results from the population-based Study of Health in Pomerania (SHIP)

scientific article

Troponin I and cardiovascular risk prediction in the general population: the BiomarCaRE consortium

scientific article published on 12 May 2016

Ultrasonographic hepatic steatosis increases prediction of mortality risk from elevated serum gamma-glutamyl transpeptidase levels.

scientific article

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

scholarly article published 19 October 2018

Urinary metabolomics reveals glycemic and coffee associated signatures of thyroid function in two population-based cohorts

scientific article

List of works by Matthias Nauck

1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

A SULT2A1 genetic variant identified by GWAS as associated with low serum DHEAS does not impact on the actual DHEA/DHEAS ratio

A catalog of genetic loci associated with kidney function from analyses of a million individuals

A descriptive analysis of relations between parents' self-reported smoking behavior and infants' daily exposure to environmental tobacco smoke

A genome-wide association study identifies novel loci associated with circulating IGF-I and IGFBP-3

A genome-wide association study identifies three loci associated with mean platelet volume

A genome-wide association study of metabolic traits in human urine

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

A mega-analysis of genome-wide association studies for major depressive disorder

A network-based approach to visualize prevalence and progression of metabolic syndrome components

A reference panel of 64,976 haplotypes for genotype imputation

Analysis of shared heritability in common disorders of the brain

Analyzing illumina gene expression microarray data from different tissues: methodological aspects of data analysis in the metaxpress consortium

Association Between Serum Testosterone and Sex Hormone-Binding Globulin and Exercise Capacity in Men: Results of the Study of Health in Pomerania (SHIP)

Association between Serum Insulin-Like Growth Factor-I Levels and Thyroid Disorders in a Population-Based Study

Association between glycemia, serum lipoproteins, and the risk of oral leukoplakia: the population-based Study of Health in Pomerania (SHIP)

Association between serum insulin-like growth factor I or IGF-binding protein 3 and estimated glomerular filtration rate: results of a population-based sample

Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

Association of alcohol consumption with allergic disease and asthma: a multi-centre Mendelian randomization analysis

Association of sex hormones with incident 10-year cardiovascular disease and mortality in women

Association of testosterone levels with endothelial function in men: results from a population-based study.

Associations between thyroid hormones and serum metabolite profiles in an euthyroid population

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

Associations of androgens with depressive symptoms and cognitive status in the general population

Associations of autozygosity with a broad range of human phenotypes

Associations of genetic determinants of serum vitamin B12 and folate concentrations with hay fever and asthma: a Mendelian randomization meta-analysis.

Associations of trauma exposure and post-traumatic stress disorder with the activity of the renin–angiotensin–aldosterone-system in the general population

Blood cis-eQTL analysis fails to identify novel association signals among sub-threshold candidates from genome-wide association studies in restless legs syndrome

Causal relationship between obesity and serum testosterone status in men: A bi-directional mendelian randomization analysis

Changes of myocardial gene expression and protein composition in patients with dilated cardiomyopathy after immunoadsorption with subsequent immunoglobulin substitution

Clinical correlates of sex hormones in women: The study of health in Pomerania

Cohort Profile: The Study of Health in Pomerania

Cohort profile: Greifswald approach to individualized medicine (GANI_MED)

Common Genetic Variation in Relation to Brachial Vascular Dimensions and Flow-Mediated Vasodilation

Common genetic variants influence human subcortical brain structures

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways ⬇️

Common variants in Mendelian kidney disease genes and their association with renal function

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

Corrigendum: 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

Corrigendum: Polygenic Architecture of Human Neuroanatomical Diversity

Defining the role of common variation in the genomic and biological architecture of adult human height

Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome

Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking

Do patients with type 1 and type 2 diabetes really have an impaired endothelial function? A population-based propensity score matching analysis

Endogenous Androgens and Sex Hormone-Binding Globulin in Women and Risk of Metabolic Syndrome and Type 2 Diabetes

Estimated daily salt intake in relation to blood pressure and blood lipids: the role of obesity.

Evidence for Stress-like Alterations in the HPA-Axis in Women Taking Oral Contraceptives

Exome Chip Analysis Identifies Low-Frequency a on Brain Magnetic Imaging

Extensive alterations of the whole-blood transcriptome are associated with body mass index: results of an mRNA profiling study involving two large population-based cohorts

Gender-specific pathway differences in the human serum metabolome

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

Genetic architecture of subcortical brain structures in 38,851 individuals

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium

Genetic determinants of serum testosterone concentrations in men.

Genetic evidence for a role of adiponutrin in the metabolism of apolipoprotein B-containing lipoproteins

Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans

Genetics of osteopontin in patients with chronic kidney disease: The German Chronic Kidney Disease study

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

Genome-Wide Association Study Identifies Variants Associated With Autoimmune Hepatitis Type 1

Genome-Wide Association Study with Targeted and Non-targeted NMR Metabolomics Identifies 15 Novel Loci of Urinary Human Metabolic Individuality

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

Genome-wide association and functional follow-up reveals new loci for kidney function

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

Genome-wide association study identifies four genetic loci associated with thyroid volume and goiter risk ⬇️

Genome-wide association study of 1,5-anhydroglucitol identifies novel genetic loci linked to glucose metabolism

Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume

Genome-wide association study of chronic periodontitis in a general German population

Genome-wide gene-environment interaction in depression: A systematic evaluation of candidate genes: The childhood trauma working-group of PGC-MDD.

Genome-wide meta-analyses of plasma renin activity and concentration reveal association with the kininogen 1 and prekallikrein genes

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits ⬇️

Health-related quality of life and IGF-1 in GH-deficient adult patients on GH replacement therapy: analysis of the German KIMS data and the Study of Health in Pomerania

Hemofiltration of recombinant hirudin by different hemodialyzer membranes: implications for clinical use.

Identification of common variants associated with human hippocampal and intracranial volumes

Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.