List of works by Claude Preudhomme

17p Deletion in acute myeloid leukemia and myelodysplastic syndrome. Analysis of breakpoints and deleted segments by fluorescence in situ

scientific article published on February 1998

A 17-gene stemness score for rapid determination of risk in acute leukaemia

scientific article published on 7 December 2016

A 17-gene-expression profile to improve prognosis prediction in childhood acute myeloid leukemia

article

A Personalized Approach to Guide Allogeneic Stem Cell Transplantation in Younger Adults with Acute Myeloid Leukemia

scientific article published on 01 September 2020

A case of refractory anemia with 17p- syndrome following azathioprine treatment for heart transplantation.

scientific article published in April 2004

A certified plasmid reference material for the standardisation of BCR-ABL1 mRNA quantification by real-time quantitative PCR

scientific article

A mutation conferring resistance to imatinib at the time of diagnosis of chronic myelogenous leukemia.

scientific article published in May 2003

A new murine aggressive leukemic model

scientific article published on 01 April 1999

A novel type of NPM1 mutation characterized by multiple internal tandem repeats in a case of cytogenetically normal acute myeloid leukemia

scholarly article by Nicolas Duployez et al published 14 June 2018 in Haematologica

A phase II study of guadecitabine in higher-risk myelodysplastic syndrome and low blast count acute myeloid leukemia after azacitidine failure

scientific article published on 07 February 2019

A randomized comparison of all transretinoic acid (ATRA) followed by chemotherapy and ATRA plus chemotherapy and the role of maintenance therapy in newly diagnosed acute promyelocytic leukemia. The European APL Group

scientific article (publication date: 15 August 1999)

A randomized phase II trial of azacitidine +/- epoetin-β in lower-risk myelodysplastic syndromes resistant to erythropoietic stimulating agents

scientific article published on 26 May 2016

A transcriptomic continuum of differentiation arrest identifies myeloid interface acute leukemias with poor prognosis

scientific article published on 13 July 2020

ASXL2 is essential for haematopoiesis and acts as a haploinsufficient tumour suppressor in leukemia.

scientific article

Absence of BCR-ABL rearrangement (with m-bcr breakpoint) in chronic myelomonocytic leukemia

scientific article published on 01 October 1994

Absence of CALR mutations in JAK2-negative polycythemia.

scientific article published on 6 October 2016

Absence of CXCR4 mutations but high incidence of double mutant in CD79A/B and MYD88 in primary central nervous system lymphoma

scientific article published on 02 February 2015

Absence of amplification of MDM2 gene, a regulator of p53 function, in myelodysplastic syndromes

scientific article published on 01 August 1993

Absence of germline mutations of exons 5 to 8 of the P53 gene in 26 breast cancer families from the north of France

scientific article published on 01 January 1993

Absence of rearrangement of the neurofibromatosis 1 (NF1) gene in myelodysplastic syndromes and acute myeloid leukemia

scientific article published on 01 May 1994

Absence of somatic mutations within the Runt domain of AML2/RUNX3 in acute myeloid leukaemia

scientific article published on 01 August 2003

Acquired alpha thalassemia myelodyslastic/myeloproliferative syndrome (ATMDS): evolution on hypomethylating agent therapy

scientific article published on 09 August 2011

Acquired trisomy 21 and distinct clonal evolution in acute megakaryoblastic leukaemia in young monozygotic twins

scientific article published on 01 September 2002

Acquisition of genomic events leading to lymphoblastic transformation in a rare case of myeloproliferative neoplasm with BCR-JAK2 fusion transcript.

scientific article

Activity of elaeochytrin A from Ferula elaeochytris on leukemia cell lines

scientific article

Activity of ladanein on leukemia cell lines and its occurrence in Marrubium vulgare.

scientific article published on 30 July 2009

Acute megakaryoblastic leukemia (excluding Down syndrome) remains an acute myeloid subgroup with inferior outcome in the French ELAM02 trial

scientific article

Acute monocytic leukemia with (8;22)(p11;q13) translocation. Involvement of 8p11 as in classical t(8;16)(p11;p13)

scientific article published on 01 June 1992

Acute myeloblastic leukemia (AML) with inv (16)(p13;q22) and the rare I type CBFbeta-MYH11 transcript: report of two new cases

scientific article published on 01 January 2002

Acute myeloid leukemia and myelodysplastic syndromes following essential thrombocythemia treated with hydroxyurea: high proportion of cases with 17p deletion.

scientific article published on January 1998

Acute myeloid leukemia with translocation t(3;5): new molecular insights.

scientific article published on 12 February 2013

Added prognostic value of secondary AML-like gene mutations in ELN intermediate-risk older AML: ALFA-1200 study results

scientific article published on 01 May 2020

Additional chromosomal abnormalities in patients with acute promyelocytic leukaemia (APL) do not confer poor prognosis: results of APL 93 trial

Allogeneic stem cell transplantation improves the outcome of adults with t(1;19)/E2A-PBX1 and t(4;11)/MLL-AF4 positive B-cell acute lymphoblastic leukemia: results of the prospective multicenter LALA-94 study

scientific article published on 12 October 2006

Allogeneic stem cell transplantation in second rather than first complete remission in selected patients with good-risk acute myeloid leukemia.

scientific article published in April 2005

Amplification of AML1 gene is present in childhood acute lymphoblastic leukemia but not in adult, and is not associated with AML1 gene mutation

scientific article published on 01 June 2002

Analysis of p16 gene deletion and point mutation in breast carcinoma

scientific article published on August 1995

Analysis of p53 antibodies in patients with various cancers define B-cell epitopes of human p53: distribution on primary structure and exposure on protein surface

article

Analyzing molecular response in chronic myeloid leukemia clinical trials: pitfalls and golden rules.

scientific article

Another pedigree with familial acute myeloid leukemia and germline CEBPA mutation

scientific article published on 23 October 2008

Are PU.1 mutations frequent genetic events in acute myeloid leukemia (AML)?

scientific article published on 01 December 2002

B7-H3 protein expression in acute myeloid leukemia

scientific article published on 17 September 2015

BACH2 promotes indolent clinical presentation in Waldenström macroglobulinemia

scientific article published on 7 June 2016

BCL2L10 is a predictive factor for resistance to azacitidine in MDS and AML patients

scientific article

BCOR and BCORL1 mutations in myelodysplastic syndromes and related disorders.

scientific article

BCR-ABL mutants spread resistance to non-mutated cells through a paracrine mechanism

scientific article published on 24 January 2008

Baseline dysmegakaryopoiesis in inherited thrombocytopenia/platelet disorder with predisposition to haematological malignancies

scientific article published on 27 February 2020

Biomarkers of Gemtuzumab Ozogamicin Response for Acute Myeloid Leukemia Treatment

scientific article published on 06 August 2020

Bromodomain inhibitor OTX015 in patients with acute leukaemia: a dose-escalation, phase 1 study

scientific article

C/EBPA methylation is common in T-ALL but not in M0 AML.

scientific article published in February 2009

C/EBPα regulated microRNA-34a targets E2F3 during granulopoiesis and is down-regulated in AML with CEBPA mutations

scientific article

CD3-CD4+ lymphoid variant of hypereosinophilic syndrome: nodal and extranodal histopathological and immunophenotypic features of a peripheral indolent clonal T-cell lymphoproliferative disorder

scientific article published on 14 February 2015

CD9 in acute myeloid leukemia: Prognostic role and usefulness to target leukemic stem cells

scientific article published on 10 February 2019

CEBPA point mutations in hematological malignancies

scientific article

Calibration of BCR-ABL1 mRNA quantification methods using genetic reference materials is a valid strategy to report results on the international scale

scientific article

Changes in the dynamics of the excess mortality rate in chronic phase-chronic myeloid leukemia over 1990-2007: a population study

scientific article published on 17 August 2011

Chromosomal Abnormalities and Prognosis in NPM1-Mutated Acute Myeloid Leukemia: A Pooled Analysis of Individual Patient Data From Nine International Cohorts

scientific article published on 20 August 2019

Chromosomal insertion involving MLL in childhood acute myeloblastic leukemia (M4)

scientific article published on 01 April 2004

Chromosomal minimal critical regions in therapy-related leukemia appear different from those of de novo leukemia by high-resolution aCGH.

scientific article

Chronic myeloproliferative disorder with t(8;22)(p11;q11) can mime clonal cytogenetic evolution of authentic chronic myelogeneous leukemia

scientific article published on 01 October 2008

Classification of CEBPA mutated acute myeloid leukemia by GATA2 mutations.

scientific article

Clinical Significance of ABCB1 in Acute Myeloid Leukemia: A Comprehensive Study

scientific article published on 06 September 2019

Clinical impact of gene mutations and lesions detected by SNP-array karyotyping in acute myeloid leukemia patients in the context of gemtuzumab ozogamicin treatment: results of the ALFA-0701 trial

scientific article

Clinical outcome of 27 imatinib mesylate-resistant chronic myelogenous leukemia patients harboring a T315I BCR-ABL mutation

scientific article published on 01 September 2007

Clinical relevance of IDH1/2 mutant allele burden during follow-up in acute myeloid leukemia. A study by the French ALFA group.

scientific article published on 22 February 2018

Clinical significance of HOX11L2 expression linked to t(5;14)(q35;q32), of HOX11 expression, and of SIL-TAL fusion in childhood T-cell malignancies: results of EORTC studies 58881 and 58951

scientific article (publication date: 15 January 2004)

Clinical significance of p53 mutations in newly diagnosed Burkitt's lymphoma and acute lymphoblastic leukemia: a report of 48 cases

scientific article published on 01 April 1995

Clinico-Biological Features and Clonal Hematopoiesis in Patients with Severe COVID-19

scientific article published on 21 July 2020

Clofarabine Improves Relapse-Free Survival of Acute Myeloid Leukemia in Younger Adults with Micro-Complex Karyotype

scientific article published on 30 December 2019

Clonal architecture of chronic myelomonocytic leukemias

scientific article published on 14 January 2013

Clonal interference of signaling mutations holds prognostic relevance in core binding factor acute myeloid leukemia.

scientific article published on 24 April 2018

Coexistence of AML1/RUNX1 and BCR-ABL point mutations in an imatinib-resistant form of CML.

scientific article

Combined immunophenotyping and in situ hybridization (FICTION): a rapid method to study cell lineage involvement in myelodysplastic syndromes

scientific article published on 01 July 1995

Comparison of TP53 mutations screening by functional assay of separated allele in yeast and next-generation sequencing in myelodysplastic syndromes

scientific article

Comparison of high-dose cytarabine and timed-sequential chemotherapy as consolidation for younger adults with AML in first remission: the ALFA-9802 study

scientific article published on 20 June 2011

Comprehensive molecular landscape in patients older than 80 years old diagnosed with acute myeloid leukemia: a study of the French Hauts-de-France AML observatory

article

Comprehensive mutational profiling of core binding factor acute myeloid leukemia

scientific article

Cooperating gene mutations in acute myeloid leukemia: a review of the literature.

scientific article published on 21 February 2008

Cooperation of activating Ras/rtk signal transduction pathway mutations and inactivating myeloid differentiation gene mutations in M0 AML: a study of 45 patients

scientific article published in March 2006

Copy-number analysis identified new prognostic marker in acute myeloid leukemia

scientific article

Core binding factor acute myeloid leukemia (CBF-AML): is high-dose Ara-C (HDAC) consolidation as effective as you think?

scientific article published on March 2009

Cryptic and partial deletions of PRDM16 and RUNX1 without t(1;21)(p36;q22) and/or RUNX1-PRDM16 fusion in a case of progressive chronic myeloid leukemia: a complex chromosomal rearrangement of underestimated frequency in disease progression?

scientific article

Cytogenetic analysis has strong independent prognostic value in de novo myelodysplastic syndromes and can be incorporated in a new scoring system: a report on 408 cases

scientific article published on 01 September 1993

Cytogenetic and molecular remission in a case of acute myeloid leukaemia(AML) with inversion of chromosome 16 (Inv(16)) and Philadelphia chromosome (Ph)

scientific article published on 01 November 1992

Cytogenetically masked CBFB-MYH11 fusion and concomitant TP53 deletion in a case of acute myeloid leukemia with a complex karyotype

scientific article published on 29 March 2020

Cytogenetics and their prognostic value in de novo acute myeloid leukaemia: a report on 283 cases

scientific article published on 01 September 1989

Dasatinib in high-risk core binding factor acute myeloid leukemia in first complete remission: a French Acute Myeloid Leukemia Intergroup trial.

scientific article published on 24 February 2015

De novo myelodysplastic syndrome (MDS) with deletion of the long arm of chromosome 20: a subtype of MDS with distinct hematological and prognostic features?

scientific article

Defective NK Cells in Acute Myeloid Leukemia Patients at Diagnosis Are Associated with Blast Transcriptional Signatures of Immune Evasion

scientific article published on 5 August 2015

Detection of BCR-ABL transcripts in chronic myeloid leukemia (CML) using a 'real time' quantitative RT-PCR assay

scientific article published on June 1999

Detection of BCR-ABL transcripts in chronic myeloid leukemia (CML) using an in situ RT-PCR assay

scientific article

Detection of a new heterozygous germline ETV6 mutation in a case with hyperdiploid acute lymphoblastic leukemia

scientific article published on 16 October 2017

Detection of p53 mutations in hematological malignancies: comparison between immunocytochemistry and DNA analysis.

scientific article published in August 1994

Detection of serum anti p53 antibodies and their correlation with p53 mutations in myelodysplastic syndromes and acute myeloid leukemia

scientific article published on 01 September 1994

Diagnosis of intrachromosomal amplification of chromosome 21 (iAMP21) by molecular cytogenetics in pediatric acute lymphoblastic leukemia

scientific article

Diagnosis, classification, and cytogenetics of myelodysplastic syndromes.

scientific article published on March 1998

Differential efficacy of adenoviral mediated gene transfer into cells from hematological cell lines and fresh hematological malignancies.

scientific article

Differential prognosis impact of IDH2 mutations in cytogenetically normal acute myeloid leukemia

scientific article published on 01 March 2011

Disease escape with the selective loss of the Philadelphia chromosome after tyrosine kinase inhibitor exposure in Ph-positive acute lymphoblastic leukemia

scientific article published on 27 January 2020

Disease evolution and outcomes in familial AML with germline CEBPA mutations

scientific article published on 10 July 2015

Down-syndrome-like acute megakaryoblastic leukemia in a patient with Cornelia de Lange syndrome

scientific article published on 7 December 2017

ETV6 is the target of chromosome 12p deletions in t(12;21) childhood acute lymphocytic leukemia

scientific article published in September 1997

Effect of gemtuzumab ozogamicin on survival of adult patients with de-novo acute myeloid leukaemia (ALFA-0701): a randomised, open-label, phase 3 study

scientific article

Effect of lenalidomide treatment on clonal architecture of myelodysplastic syndromes without 5q deletion

scientific article published on December 2015

Effect of priming with granulocyte-macrophage colony-stimulating factor in younger adults with newly diagnosed acute myeloid leukemia: a trial by the Acute Leukemia French Association (ALFA) Group.

scientific article

Effects of azacitidine in 93 patients with IDH1/2 mutated acute myeloid leukemia/myelodysplastic syndromes: a French retrospective multicenter study

scientific article published on 12 October 2020

Efficacy of Tyrosine Kinase Inhibitor Therapy in a Chemotherapy-refractory B-cell Precursor Acute Lymphoblastic Leukemia With ZC3HAV1-ABL2 Fusion

scientific article published on 04 June 2019

Efficacy of thalidomide in a child with histiocytic sarcoma following allogeneic bone marrow transplantation for T-ALL.

scientific article published in October 2003

Epidemiologic study on survival of chronic myeloid leukemia and Ph(+) acute lymphoblastic leukemia patients with BCR-ABL T315I mutation

scientific article published on 20 October 2009

Epidemiology, clinical picture and long-term outcomes of FIP1L1-PDGFRA-positive myeloid neoplasm with eosinophilia: data from 151 patients

scientific article published on 28 July 2020

Evaluation of allogeneic hematopoietic SCT in younger adults with adverse karyotype AML

scientific article published on 19 March 2012

Evaluation of minimal residual disease using reverse-transcription polymerase chain reaction in t(8;21) acute myeloid leukemia: a multicenter study of 51 patients

scientific article published on 01 February 2000

Expression of lung resistance protein and correlation with other drug resistance proteins and outcome in myelodysplastic syndromes.

scientific article published in May 1998

Expression of the multidrug resistance P-glycoprotein and its relationship to hematological characteristics and response to treatment in myelodysplastic syndromes.

scientific article published in June 1994

Expression of the multidrug resistance-associated protein in myelodysplastic syndromes

scientific article published on September 2000

Extensive mutational status of genes and clinical outcome in pediatric acute myeloid leukemia.

scientific article

FISH analysis with a YAC probe improves detection of LAZ3/BCL6 rearrangement in non-Hodgkin's lymphoma.

scientific article published in January 2000

Factors predicting molecular and cytogenetic response in chronic myeloid leukemia patients treated with imatinib.

scientific article published in January 2005

Familial CEBPA-mutated acute myeloid leukemia

scientific article

Familial myeloid malignancies with germline TET2 mutation

scientific article published on 11 December 2019

Fast multiclonal clusterization of V(D)J recombinations from high-throughput sequencing

scientific article

Favorable prognostic significance of CEBPA mutations in patients with de novo acute myeloid leukemia: a study from the Acute Leukemia French Association (ALFA)

scientific article published on 01 October 2002

Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up

scientific article published on 26 March 2018

Fluorescence in situ hybridization improves the detection of monosomy 7 in myelodysplastic syndromes

scientific article published on 01 June 1994

Fractionated gemtuzumab ozogamicin and standard dose cytarabine produced prolonged second remissions in patients over the age of 55 years with acute myeloid leukemia in late first relapse

scientific article

Frequency of molecular elimination of Ph1 clone in chronic myelogenous leukemia (CML) with interferon alpha

scientific article published on 01 January 1996

Frequent ASXL2 mutations in acute myeloid leukemia patients with t(8;21)/RUNX1-RUNX1T1 chromosomal translocations.

scientific article

GILZ inhibits the mTORC2/AKT pathway in BCR-ABL(+) cells.

scientific article published in August 2011

Gemtuzumab ozogamicin for acute myeloid leukemia: final efficacy and safety updates from the open-label, phase III ALFA-0701 trial

scholarly article by Juliette Lambert et al published January 2019 in Haematologica

Gene transfer of GM-CSF, CD80 and CD154 cDNA enhances survival in a murine model of acute leukemia with persistence of a minimal residual disease.

scientific article published in August 2000

Genetic analysis of therapy-related myeloid neoplasms occurring after intensive treatment for acute promyelocytic leukemia

scientific article published on 18 April 2018

Genetic identification of patients with AML older than 60 years achieving long-term survival with intensive chemotherapy

scientific article published in 2021

Genetic polymorphisms associated with increased risk of developing chronic myelogenous leukemia

scientific article published on 12 October 2015

Genetic typing of CBL, ASXL1, RUNX1, TET2 and JAK2 in juvenile myelomonocytic leukaemia reveals a genetic profile distinct from chronic myelomonocytic leukaemia

scientific article published on 19 October 2010

Genome wide SNP array identified multiple mechanisms of genetic changes in Waldenstrom macroglobulinemia.

scientific article

Genomic Landscape of CXCR4 Mutations in Waldenström Macroglobulinemia

scientific article published on 21 October 2015

Genomic characterization of Imatinib resistance in CD34+ cell populations from chronic myeloid leukaemia patients

scientific article published on 03 August 2010

Genomic structure and assignment of the RhoH/TTF small GTPase gene (ARHH) to 4p13 by in situ hybridization

scientific article

Germ-line GATA2 p.THR354MET mutation in familial myelodysplastic syndrome with acquired monosomy 7 and ASXL1 mutation demonstrating rapid onset and poor survival.

scientific article

Germline PAX5 mutation predisposes to familial B acute lymphoblastic leukemia

scientific article published on 09 October 2020

Germline RUNX1 Intragenic Deletion: Implications for Accurate Diagnosis of FPD/AML

scientific article published on 04 June 2019

Germline pathogenic variants in transcription factors predisposing to pediatric acute myeloid leukemia: results from the French ELAM02 trial

scientific article published on 18 June 2020

Glutathione S transferase theta 1 gene defects in myelodysplastic syndromes and their correlation with karyotype and exposure to potential carcinogens.

scientific article published in September 1997

Good correlation between RT-PCR analysis and relapse in Philadelphia (Ph1)-positive acute lymphoblastic leukemia (ALL)

scientific article published on 01 February 1997

Good predictive value of combined cytogenetic and molecular follow up in chronic myelogenous leukemia after non T-cell depleted allogeneic bone marrow transplantation: a report on 38 consecutive cases

scientific article published on 01 July 1995

Granulomonocytic progenitors are key target cells of azacytidine in higher risk myelodysplastic syndromes and acute myeloid leukemia

scholarly article by Ashfaq Ali et al published 26 February 2018 in Leukemia

Haematological spectrum and genotype-phenotype correlations in nine unrelated families with RUNX1 mutations from the French network on inherited platelet disorders

scientific article

High WT1 expression after induction therapy predicts high risk of relapse and death in pediatric acute myeloid leukemia.

scientific article

High frequency of RUNX1 biallelic alteration in acute myeloid leukemia secondary to familial platelet disorder.

scientific article published on 8 April 2009

High imatinib dose overcomes insufficient response associated with ABCG2 haplotype in chronic myelogenous leukemia patients

scientific article published on October 2013

High incidence of biallelic point mutations in the Runt domain of the AML1/PEBP2 alpha B gene in Mo acute myeloid leukemia and in myeloid malignancies with acquired trisomy 21

scientific article published on 01 October 2000

High occurrence of JAK2 V617 mutation in refractory anemia with ringed sideroblasts associated with marked thrombocytosis

scientific article published on 21 September 2006

High-throughput sequencing in acute lymphoblastic leukemia: Follow-up of minimal residual disease and emergence of new clones.

scientific article published on 21 November 2016

Horizontal meta-analysis identifies common deregulated genes across AML subgroups providing a robust prognostic signature

scientific article published on 01 October 2020

How should we diagnose and treat blastic plasmacytoid dendritic cell neoplasm patients?

scientific article published on 01 December 2019

Humulane and germacrane sesquiterpenes from Ferula lycia

scientific article published in April 2010

IDH1/2 but not DNMT3A mutations are suitable targets for minimal residual disease monitoring in acute myeloid leukemia patients: a study by the Acute Leukemia French Association

scientific article published on 13 October 2015

Identification of a YAC spanning the translocation breakpoint t(8;22) associated with acute monocytic leukemia

scientific article published on 01 March 1996

IgH/TCR rearrangements are common in MLL translocated adult AML and suggest an early T/myeloid or B/myeloid maturation arrest, which correlates with the MLL partner

scientific article published on 01 December 2005

Imatinib plus peginterferon alfa-2a in chronic myeloid leukemia

scientific article

Immature platelet fraction (IPF): A reliable tool to predict peripheral thrombocytopenia

scientific article published on 12 April 2019

Immunoglobulin and T-cell receptor delta gene rearrangements are rarely found in myelodysplastic syndromes in chronic phase

scientific article published on 01 May 1994

Immunological detection of myeloperoxidase in poorly differentiated acute leukemia

scientific article published on 01 March 1993

Impact of TET2 mutations on response rate to azacitidine in myelodysplastic syndromes and low blast count acute myeloid leukemias

scientific article published on 15 April 2011

Impact of Wilms' tumor 1 expression on outcome of patients undergoing allogeneic stem cell transplantation for AML

scientific article published on 09 January 2017

Impact of additional genetic alterations on the outcome of patients with NPM1-mutated cytogenetically normal acute myeloid leukemia.

scientific article published on 31 December 2014

Improved cytogenetic analysis of bone marrow plasma cells after cytokine stimulation in multiple myeloma: a report on 46 patients.

scientific article

Inactivation of the p53 gene in leukemias and myelodysplastic syndrome (MDS) with 17p monosomy

scientific article published on 01 December 1994

Inactivation of the retinoblastoma gene appears to be very uncommon in myelodysplastic syndromes

scientific article published on 01 May 1994

Incidence and prognostic impact of c-Kit, FLT3, and Ras gene mutations in core binding factor acute myeloid leukemia (CBF-AML).

scientific article published in June 2006

Incidence and prognostic value of TET2 alterations in de novo acute myeloid leukemia achieving complete remission.

scientific article published on 20 May 2010

Incidence of ATRX mutations in myelodysplastic syndromes, the value of microcytosis.

scientific article

Increased risk of adverse acute myeloid leukemia after anti-CD19-targeted immunotherapies in KMT2A-rearranged acute lymphoblastic leukemia: a case report and review of the literature

scientific article published on 07 January 2019

Inherited transmission of the CSF3R T618I mutational hotspot in familial chronic neutrophilic leukemia

scientific article published on 01 December 2019

Interferon decreases VEGF levels in patients with chronic myeloid leukemia treated with imatinib.

scientific article published in February 2014

Investigation of minimal residual disease in adult Ph1 positive acute lymphoblastic leukemia by a combination of cell sorting and fluorescence in situ hybridization: a preliminary study on 6 cases

scientific article published on 01 June 2000

Involvement of a common progenitor cell in core binding factor acute myeloid leukaemia associated with mastocytosis

scientific article published on 04 August 2012

Involvement of peripheral blood cells in multiple myeloma: chromosome changes are the rule within circulating plasma cells but not within B lymphocytes

scientific article published on 01 July 1997

Is apoptosis a massive process in myelodysplastic syndromes?

scientific article published on 01 November 1996

Is translocation (8;21) a "favorable" cytogenetic rearrangement in acute myeloid leukemia?

scientific article published on 01 January 1990

JAK2V617F-positive polycythemia vera and Philadelphia chromosome-positive chronic myeloid leukemia: one patient with two distinct myeloproliferative disorders.

scientific article

LXR agonist treatment of blastic plasmacytoid dendritic cell neoplasm restores cholesterol efflux and triggers apoptosis.

scientific article published on 04 October 2016

Lenalidomide with or without erythropoietin in transfusion-dependent erythropoiesis-stimulating agent-refractory lower-risk MDS without 5q deletion.

scientific article published on 26 October 2015

Linezolid induces ring sideroblasts

scientific article published on November 2013

Long-term follow-up of de novo myelodysplastic syndromes treated with intensive chemotherapy: incidence of long-term survivors and outcome of partial responders

scientific article published on 01 September 1997

Low-dose imatinib mesylate leads to rapid induction of major molecular responses and achievement of complete molecular remission in FIP1L1-PDGFRA-positive chronic eosinophilic leukemia

scientific article published on 13 February 2007

M0 AML, clinical and biologic features of the disease, including AML1 gene mutations: a report of 59 cases by the Groupe Français d'Hématologie Cellulaire (GFHC) and the Groupe Français de Cytogénétique Hématologique (GFCH)

scientific article published on 10 October 2002

MDM2 gene amplification in human breast cancer

scientific article published on 01 January 1994

MOZ is fused to p300 in an acute monocytic leukemia with t(8;22).

scientific article

MRD assessed by WT1 and NPM1 transcript levels identifies distinct outcomes in AML patients and is influenced by gemtuzumab ozogamicin

scientific article

MYD88 L265P mutation contributes to the diagnosis of Bing Neel syndrome

scientific article

MYD88 L265P mutation in Waldenstrom macroglobulinemia.

scientific article published on 26 March 2013

Mesenchymal cells generated from patients with myelodysplastic syndromes are devoid of chromosomal clonal markers and support short- and long-term hematopoiesis in vitro.

scientific article

Methylation of the p15(INK4b) gene in myelodysplastic syndromes is frequent and acquired during disease progression

scientific article published on 01 April 1998

Microparticle phenotypes are associated with driver mutations and distinct thrombotic risks in essential thrombocythemia.

scientific article published on 31 May 2016

Minimal Residual Disease assessment of IDH1/2 mutations in Acute Myeloid Leukemia by LNA-RQ-PCR.

scientific article published in March 2016

Minimal residual disease monitoring based on FLT3 internal tandem duplication in adult acute myeloid leukemia.

scientific article published on 29 November 2011

Minimal residual disease monitoring in t(8;21) acute myeloid leukemia based on RUNX1-RUNX1T1 fusion quantification on genomic DNA

scientific article published on 08 March 2014

Minimal/measurable residual disease in AML: consensus document from ELN MRD Working Party.

scientific article published on 12 January 2018

Molecular Profiling Defines Distinct Prognostic Subgroups in Childhood AML: A Report From the French ELAM02 Study Group

scientific article published on 01 January 2018

Molecular characterization of the idiopathic hypereosinophilic syndrome (HES) in 35 French patients with normal conventional cytogenetics.

scientific article

Molecular predictors of response to decitabine in advanced chronic myelomonocytic leukemia: a phase 2 trial.

scientific article

Molecular prognostic factors in acute myeloid leukemia receiving first-line therapy with azacitidine

scientific article published on 19 November 2015

Molecular remission in chronic myeloid leukemia patients with sustained complete cytogenetic remission after imatinib mesylate treatment

scientific article published in February 2006

Multi-loci diagnosis of acute lymphoblastic leukaemia with high-throughput sequencing and bioinformatics analysis

scientific article published on 21 February 2016

Mutation allele burden remains unchanged in chronic myelomonocytic leukaemia responding to hypomethylating agents

scientific article published on 24 February 2016

Mutation analysis of TET2, IDH1, IDH2 and ASXL1 in chronic myeloid leukemia

scientific article published on 03 June 2011

Mutation in RAP1 is a rare event in myelodysplastic syndromes.

scientific article

Mutation status and clinical outcome of 89 imatinib mesylate-resistant chronic myelogenous leukemia patients: a retrospective analysis from the French intergroup of CML (Fi(phi)-LMC GROUP)

scientific article published on 01 June 2006

Mutational profile and benefit of gemtuzumab ozogamicin in acute myeloid leukemia

scientific article published on 01 February 2020

Mutational profiling of isolated myeloid sarcomas and utility of serum 2HG as biomarker of IDH1/2 mutations

scientific article published on 26 February 2018

Mutations affecting mRNA splicing define distinct clinical phenotypes and correlate with patient outcome in myelodysplastic syndromes.

scientific article

Mutations in the ABL kinase domain pre-exist the onset of imatinib treatment.

scientific article

Mutations of PTPN11 are rare in adult myeloid malignancies

scientific article

Mutations of the P53 gene in acute myeloid leukaemia

scientific article published on 01 February 1992

Mutations of the p53 gene in B-cell chronic lymphocytic leukemia: a report on 39 cases with cytogenetic analysis

scientific article published on April 1, 1992

Mutations of the p53 gene in B-cell lymphoblastic acute leukemia: a report on 60 cases

scientific article published on 01 January 1992

Myelodysplasia and leukemia of Fanconi anemia are associated with a specific pattern of genomic abnormalities that includes cryptic RUNX1/AML1 lesions

scientific article published on 16 February 2011

Myelodysplasia during the course of myeloma. Restriction of 17p deletion and p53 overexpression to myeloid cells

scientific article published on 01 February 1998

Myelodysplastic syndromes and acute leukemia with genetic predispositions: a new challenge for hematologists.

scientific article published on 7 November 2016

Myelodysplastic syndromes and acute myeloid leukemia with 17p deletion. An entity characterized by specific dysgranulopoïesis and a high incidence of P53 mutations

scientific article published on 01 March 1995

NOTCH1 and FBXW7 mutations have a favorable impact on early response to treatment, but not on outcome, in children with T-cell acute lymphoblastic leukemia (T-ALL) treated on EORTC trials 58881 and 58951.

scientific article published on 23 September 2010

NUP214-ABL1 fusion defines a rare subtype of B-cell precursor acute lymphoblastic leukemia that could benefit from tyrosine kinase inhibitors

scientific article published on 17 December 2015

Natural history of GATA2 deficiency in a survey of 79 French and Belgian patients

article

Neurofibromatosis-1 gene deletions and mutations in de novo adult acute myeloid leukemia

scientific article published on 5 March 2013

New mechanisms of AML1 gene alteration in hematological malignancies

scientific article

Next-generation sequencing of FLT3 internal tandem duplications for minimal residual disease monitoring in acute myeloid leukemia

scientific article

Nonrandom 4p13 rearrangements of the RhoH/TTF gene, encoding a GTP-binding protein, in non-Hodgkin's lymphoma and multiple myeloma

scientific article

Occupational and environmental risk factors of the myelodysplastic syndromes in the North of France.

scientific article published in March 2001

Oncogene- and drug resistance-associated alternative exon usage in acute myeloid leukemia (AML).

scientific article published on 12 May 2015

Oncogenetic mutations combined with MRD improve outcome prediction in pediatric T-cell acute lymphoblastic leukemia.

scientific article

Origin of resistance to Imatinib mesylate: lessons learned from this experience

scientific article published in December 2004

Outcome of older patients with acute myeloid leukemia in first relapse

scientific article published on 7 August 2013

Outcome of treatment after first relapse in younger adults with acute myeloid leukemia initially treated by the ALFA-9802 trial

scientific article published on 28 May 2012

Outcomes and mutational analysis of patients with lower-risk non-del5q myelodysplastic syndrome treated with antithymocyte globulin with or without ciclosporine A

scientific article published on 29 May 2018

Over-expression of the MDM2 gene is found in some cases of haematological malignancies.

scientific article published in October 1994

PAX5 mutations occur frequently in adult B-cell progenitor acute lymphoblastic leukemia and PAX5 haploinsufficiency is associated with BCR-ABL1 and TCF3-PBX1 fusion genes: a GRAALL study.

scientific article published on 9 July 2009

Paroxysmal nocturnal hemoglobinuria (PNH) and T cell large granular lymphocyte (LGL) leukemia--an unusual association: another cause of cytopenia in PNH

scientific article published on 09 July 2015

Partial duplication of the MLL oncogene in patients with aggressive acute myeloid leukemia.

scientific article published in April 2004

Peripheral blood minimal/measurable residual disease assessed in flow cytometry in acute myeloblastic leukemia

scientific article published on 05 February 2019

Persistence of AML1/ETO fusion mRNA in t(8;21) acute myeloid leukemia (AML) in prolonged remission: is there a consensus?

scientific article published on 01 January 1996

Phenotypic and genotypic characterization of azacitidine-sensitive and resistant SKM1 myeloid cell lines

scientific article

Philadelphia negative, BCR-ABL positive adult acute lymphoblastic leukemia (ALL) in 2 of 39 patients with combined cytogenetic and molecular analysis

scientific article published on 01 July 1993

Plasmacytoid dendritic cells proliferation associated with acute myeloid leukemia: phenotype profile and mutation landscape

scientific article published on 13 October 2020

Polycomb repressive complex 2 haploinsufficiency identifies a high-risk subgroup of pediatric acute myeloid leukemia

scientific article published on 27 June 2018

Poor prognosis of chromosome 7 clonal aberrations in Philadelphia-negative metaphases and relevance of potential underlying myelodysplastic features in chronic myeloid leukemia

scientific article published on 20 December 2018

Postinduction Minimal Residual Disease Predicts Outcome and Benefit From Allogeneic Stem Cell Transplantation in Acute Myeloid Leukemia With NPM1 Mutation: A Study by the Acute Leukemia French Association Group.

scientific article

Postremission treatment of elderly patients with acute myeloid leukemia in first complete remission after intensive induction chemotherapy: results of the multicenter randomized Acute Leukemia French Association (ALFA) 9803 trial

scientific article

Prevalence, clinical profile, and prognosis of NPM mutations in AML with normal karyotype

scientific article

Prognosis and monitoring of core-binding factor acute myeloid leukemia: current and emerging factors

scientific article

Prognostic Role of Gene Mutations in Chronic Myelomonocytic Leukemia Patients Treated With Hypomethylating Agents.

scientific article published on 25 April 2018

Prognostic impact of isocitrate dehydrogenase enzyme isoforms 1 and 2 mutations in acute myeloid leukemia: a study by the Acute Leukemia French Association group

scientific article published on 12 July 2010

Prognostic score including gene mutations in chronic myelomonocytic leukemia.

scientific article

Prognostic significance of DNA methyltransferase 3A mutations in cytogenetically normal acute myeloid leukemia: a study by the Acute Leukemia French Association

scientific article

Prognostic significance of FLT3 internal tandem repeat in patients with de novo acute myeloid leukemia treated with reinforced courses of chemotherapy

scientific article published on 01 September 2002

Prognostic significance of p16INK4a immunocytochemistry in adult ALL with standard risk karyotype

scientific article published in July 2001

Prognostic value of TP53 gene mutations in myelodysplastic syndromes and acute myeloid leukemia treated with azacitidine

scientific article

Prognostic value of c-mpl expression in myelodysplastic syndromes

scientific article published on 01 May 1995

Prognostic value of dysmyelopoietic features in de novo acute myeloid leukaemia: a report on 132 patients

scientific article published on 01 January 1990

Prognostic value of minimal residual disease by real-time quantitative PCR in acute myeloid leukemia with CBFB-MYH11 rearrangement: the French experience

scientific article published on 27 May 2010

Prognostic value of multicenter flow cytometry harmonized assessment of minimal residual disease in acute myeloblastic leukemia.

scientific article

Prognostic value of real-time quantitative PCR (RQ-PCR) in AML with t(8;21).

scientific article published on March 2005

Prospective evaluation of gene mutations and minimal residual disease in patients with core binding factor acute myeloid leukemia

scientific article

Prospective long-term minimal residual disease monitoring using RQ-PCR in RUNX1-RUNX1T1-positive acute myeloid leukemia: results of the French CBF-2006 trial

scientific article published on 3 December 2015

Prospective multicentric molecular study for poor prognosis fusion transcripts at diagnosis in adult B-lineage ALL patients: the LALA 94 experience

scientific article published on 12 October 2006

Quantification of EVI1 transcript levels in acute myeloid leukemia by RT-qPCR analysis: A study by the ALFA Group.

scientific article published on 9 October 2015

Quantification of JAK2V617F mutation by next-generation sequencing technology.

scientific article published on 13 May 2013

RNA for reverse PCR analysis can be obtained from bone marrow cells prepared for cytogenetic analysis and stored at -20 degrees C for several years

scientific article published on 01 August 1995

RUNX1 DNA-binding mutations and RUNX1-PRDM16 cryptic fusions in BCR-ABL+ leukemias are frequently associated with secondary trisomy 21 and may contribute to clonal evolution and imatinib resistance.

scientific article published on 17 January 2008

Randomized Phase II Study of Clofarabine-Based Consolidation for Younger Adults With Acute Myeloid Leukemia in First Remission

scientific article published on 21 February 2017

Randomized comparison of double induction and timed-sequential induction to a "3 + 7" induction in adults with AML: long-term analysis of the Acute Leukemia French Association (ALFA) 9000 study

article

Randomized study of intensified anthracycline doses for induction and recombinant interleukin-2 for maintenance in patients with acute myeloid leukemia age 50 to 70 years: results of the ALFA-9801 study

scientific article published on 4 January 2010

Rare occurrence of P53 gene mutations in multiple myeloma

scientific article published on 01 July 1992

Rare occurrence of mutations of the FLR exon of the neurofibromatosis 1 (NF1) gene in myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML)

scientific article published on 01 July 1993

Reactive oxygen species levels control NF-κB activation by low dose deferasirox in erythroid progenitors of low risk myelodysplastic syndromes

scientific article published on 6 November 2017

Real-time quantitative polymerase chain reaction detection of minimal residual disease by standardized WT1 assay to enhance risk stratification in acute myeloid leukemia: a European LeukemiaNet study.

scientific article

Recurrent in-frame insertion in C/EBPα TAD2 region is a polymorphism without prognostic value in AML

scientific article published on 13 September 2007

Relationship between p53 gene mutations and multidrug resistance (mdr1) gene expression in myelodysplastic syndromes

scientific article published on 01 November 1993

Restoration of hematopoiesis in a case of myelodysplastic syndrome associated with systemic lupus erythematosus treated with rituximab

scientific article published on 07 April 2015

Role of IRF4 in resistance to immunomodulatory (IMid) compounds® in Waldenström's macroglobulinemia.

scientific article published on 4 December 2017

Role of multiplex FISH in identifying chromosome involvement in myelodysplastic syndromes and acute myeloid leukemias with complex karyotypes: a report on 28 cases

scientific article published on 01 March 2005

SET-NUP214 is a recurrent γδ lineage-specific fusion transcript associated with corticosteroid/chemotherapy resistance in adult T-ALL

scientific article published on 21 January 2014

SETBP1 mutations in 658 patients with myelodysplastic syndromes, chronic myelomonocytic leukemia and secondary acute myeloid leukemias.

scientific article published on 5 February 2013

SNP-array lesions in core binding factor acute myeloid leukemia

scientific article published on 8 January 2018

Serum 2-hydroxyglutarate production in IDH1- and IDH2-mutated de novo acute myeloid leukemia: a study by the Acute Leukemia French Association group.

scientific article

Several types of mutations of the Abl gene can be found in chronic myeloid leukemia patients resistant to STI571, and they can pre-exist to the onset of treatment.

scientific article

Shared clonal IGH rearrangement in BCP-ALL occurring after CLL: pitfalls and implications for MRD monitoring

scientific article published on 05 August 2020

Significance of circulating plasma cells in multiple myeloma

scientific article published on 01 August 1994

Slow relapse in acute myeloid leukemia with inv(16) or t(16;16).

scientific article published on 16 July 2009

Somatic mutations associated with leukemic progression of familial platelet disorder with predisposition to acute myeloid leukemia

scientific article published on 28 August 2015

Successful treatment of imatinib-resistant acute megakaryoblastic leukemia with e6a2 BCR/ABL: use of dasatinib and reduced-conditioning stem-cell transplantation

scientific article published on 07 June 2007

Superior long-term outcome with idarubicin compared with high-dose daunorubicin in patients with acute myeloid leukemia age 50 years and older

scientific article

Sustained molecular response with imatinib in a leukemic form of idiopathic hypereosinophilic syndrome in relapse after allograft.

scientific article published in February 2004

T-cell acute lymphoblastic leukemia occurring in the course of B cell chronic lymphocytic leukemia: a case report.

scientific article published on July 1995

TET2 exon 2 skipping is an independent favorable prognostic factor for cytogenetically normal acute myelogenous leukemia (AML): TET2 exon 2 skipping in AML.

scientific article published on 16 January 2017

TET2 mutation is an independent favorable prognostic factor in myelodysplastic syndromes (MDSs).

scientific article

TP53 mutation and its prognostic significance in Waldenstrom's Macroglobulinemia

scientific article

TPA stimulation culture for improved detection of t(11;14)(q13;q32) in mantle cell lymphoma

scientific article

Telomere deregulations possess cytogenetic, phenotype, and prognostic specificities in acute leukemias.

scientific article

Tetraspanin CD81 is an adverse prognostic marker in acute myeloid leukemia.

scientific article published on 22 August 2016

The Arg200Trp mutation in the human tissue factor gene

article

The Folate Cycle Enzyme MTHFR is a Critical Regulator of Cell Response to MYC-Targeting Therapies

scientific article published on 21 August 2020

The Need for a Consensus Next-generation Sequencing Panel for Mature Lymphoid Malignancies

scientific article published on 27 December 2018

The Spectrum of FIP1L1-PDGFRA-Associated Chronic Eosinophilic Leukemia: New Insights Based on a Survey of 44 Cases

scientific article

The clinical significance of mutations of the P53 tumour suppressor gene in haematological malignancies

scientific article published on September 1997

The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants

scientific article published on 25 February 2020

The favorable impact of CEBPA mutations in patients with acute myeloid leukemia is only observed in the absence of associated cytogenetic abnormalities and FLT3 internal duplication.

scientific article published on 16 March 2009

The level of blast CD33 expression positively impacts the effect of gemtuzumab ozogamicin in patients with acute myeloid leukemia

scientific article published on 29 February 2016

The molecular anatomy of the FIP1L1-PDGFRA fusion gene.

scientific article published on 6 November 2008

The prognosis impact of BCR-ABL P-loop mutations: worse or not worse?

scientific article published on 01 February 2007

The retinoblastoma gene (RB-1) status in multiple myeloma: a report on 35 cases.

scientific article published in August 1995

The role of cytogenetic abnormalities in acute myeloid leukemia with NPM1 mutations and no FLT3 internal tandem duplication

scientific article published in November 2009

The role of intensive chemotherapy in myelodysplastic syndromes.

scientific article published on September 1992

The severity of FIP1L1-PDGFRA-positive chronic eosinophilic leukaemia is associated with polymorphic variation at the IL5RA locus.

scientific article published on 4 October 2007

The stem cell-associated gene expression signature allows risk stratification in pediatric acute myeloid leukemia

scientific article published on 08 August 2018

Therapy related myelodysplastic syndrome and leukemia with no "unfavourable" cytogenetic findings have a good response to intensive chemotherapy: a report on 15 cases

scientific article published on 01 January 1991

Therapy-related acute lymphoblastic leukemia with MLL rearrangement following treatment of Burkitt's leukemia

scientific article published on 01 June 2005

Therapy-related myelodysplastic syndrome and acute myeloid leukemia with 17p deletion. A report on 25 cases

scientific article published on 01 February 1999

Tolerability and efficacy of pegylated interferon-α-2a in combination with imatinib for patients with chronic-phase chronic myeloid leukemia

scientific article published on 16 September 2013

Transcriptomic and genomic heterogeneity in blastic plasmacytoid dendritic cell neoplasms: from ontogeny to oncogenesis

scientific article published in 2021

Transfer of p16inka/CDKN2 gene in leukaemic cell lines inhibits cell proliferation

scientific article published on November 1996

Unlike AML1, CBFbeta gene is not deregulated by point mutations in acute myeloid leukemia and in myelodysplastic syndromes

scientific article published on 01 May 2002

Unlike ASXL1 and ASXL2 mutations, ASXL3 mutations are rare events in acute myeloid leukemia with t(8;21)

scientific article published on 15 May 2015

Very low incidence of p53 antibodies in adult non-Hodgkin's lymphoma and multiple myeloma

scientific article published on 01 January 1998

Vitamin D Receptor Controls Cell Stemness in Acute Myeloid Leukemia and in Normal Bone Marrow

scientific article published on 01 January 2020

Which AML subsets benefit from leukemic cell priming during chemotherapy? Long-term analysis of the ALFA-9802 GM-CSF study.

scientific article published in April 2010

Wilms tumor 1 (WT1) gene mutations in pediatric T-cell malignancies.

scientific article published on 22 October 2009

Wilms tumor 1 gene mutations are associated with a higher risk of recurrence in young adults with acute myeloid leukemia: a study from the Acute Leukemia French Association

scientific article

Wilms' tumor 1 single-nucleotide polymorphism rs16754 does not predict clinical outcome in adult acute myeloid leukemia

scientific article published on 15 July 2011

[Residual disease: the hematologist's point of view]

scientific article published on 01 June 2001

[Serous non-Hodgkin's lymphoma in immunocompetent patient]

scientific article published on 01 February 2002

bcl-2 expression in myelodysplastic syndromes and its correlation with hematological features, p53 mutations and prognosis

scientific article published on 01 April 1995

de novo myelodysplastic syndromes in adults aged 50 or less. A report on 37 cases

scientific article published in January 1990

mutation is not associated with prolonged complete remission in acute myeloid leukemia patients treated with hypomethylating agents

scholarly article by Pedro Henrique Prata et al published October 2018 in Haematologica

p16 gene homozygous deletions in acute lymphoblastic leukemia

scientific article published on 01 February 1995

p16ink4a gene and hematological malignancies.

scientific article published on June 1996

p190 bcr-abl rearrangement: a secondary cytogenetic event in some chronic myeloid disorders?

scientific article

p53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies

scientific article published on 01 November 1994

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