RUNX1 DNA-binding mutations and RUNX1-PRDM16 cryptic fusions in BCR-ABL+ leukemias are frequently associated with secondary trisomy 21 and may contribute to clonal evolution and imatinib resistance.

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Description scientific article published on 17 January 2008
Author/s

author: Sélim Corm  Sami Joha  Jean-Luc Laï  Fi-LMC group  Lauréline Deluche  Catherine Roche-Lestienne  Franck E Nicolini  Claude Preudhomme  Isabelle Tigaud 

Publication date January 17, 2008
Language English
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