List of works by Mark Caulfield

2013 ESH/ESC guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).

scientific article

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

scientific article

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

scientific article published on 24 March 2017

A blood pressure-associated variant of the SLC39A8 gene influences cellular cadmium accumulation and toxicity

scientific article published on 27 July 2016

A deleterious gene-by-environment interaction imposed by calcium channel blockers in Marfan syndrome.

scientific article

A genetic risk score is associated with statin-induced low-density lipoprotein cholesterol lowering

scientific article published on 5 April 2016

A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium

scientific article published on 30 December 2016

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

scientific article published on 10 April 2019

ADAMTS7 cleavage and vascular smooth muscle cell migration is affected by a coronary-artery-disease-associated variant

scientific article published on 14 February 2013

Absence of linkage of the epithelial sodium channel to hypertension in black Caribbeans.

scientific article published on August 1998

Advances in blood pressure genomics

scientific article published on May 2013

Ambulatory blood pressure monitoring and 24-h blood pressure control as predictors of outcome in treated hypertensive patients

article published in 2001

Ambulatory blood pressure monitoring predicts cardiovascular events in treated hypertensive patients--an Anglo-Scandinavian cardiac outcomes trial substudy.

scientific article

Analysis with the exome array identifies multiple new independent variants in lipid loci

scientific article published on 27 July 2016

Angiotensinogen in human essential hypertension

scientific article

Anglo-Scandinavian Cardiac Outcomes Trial: a brief history, rationale and outline protocol

scientific article published in August 2001

Association of WNK1 gene polymorphisms and haplotypes with ambulatory blood pressure in the general population

scientific article

Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study

scientific article

Association of hypertension drug target genes with blood pressure and hypertension in 86,588 individuals

scientific article

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

scientific article

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Atheromatous vascular disease and ischaemic stroke in the UK.

scientific article

Author Correction: Nuclear-mitochondrial DNA segments resemble paternally inherited mitochondrial DNA in humans

scientific article published on 22 July 2020

Authors' reply to Harding and colleagues, Taylor, Cruickshank, and El Turabi and Payne

scientific article published in the British Medical Journal

Automatic on-line extraction coupled with electrochemical detection as an improved method for the HPLC co-analysis of codeine and morphine in plasma and gastric juice.

scientific article published in January 1990

Bayesian refinement of association signals for 14 loci in 3 common diseases

scientific article published on 28 October 2012

Biological, clinical and population relevance of 95 loci for blood lipids

scientific article

Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people

scientific article

Blood pressure loci identified with a gene-centric array

scientific article

Cardiovascular risk factors in a cohort of 30 000 high-risk men and women in the UK: cross-sectional, retrospective and prospective studies of screenees for the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT)

scientific article published on 01 August 2001

Causal Associations of Adiposity and Body Fat Distribution with Coronary Heart Disease, Stroke Subtypes and Type 2 Diabetes: A Mendelian Randomization Analysis

scientific article

Chromosome 2p Shows Significant Linkage to Antihypertensive Response in the British Genetics of Hypertension Study

article

Combination Therapy Is Superior to Sequential Monotherapy for the Initial Treatment of Hypertension: A Double-Blind Randomized Controlled Trial.

scientific article published on 18 November 2017

Common Polymorphisms at the CYP17A1 Locus Associate With Steroid Phenotype: Support for Blood Pressure Genome-Wide Association Study Signals at This Locus

scientific article published on 22 February 2016

Common Polymorphisms in the CYP11B1 and CYP11B2 Genes: Evidence for a Digenic Influence on Hypertension

article

Common genetic variation near the phospholamban gene is associated with cardiac repolarisation: meta-analysis of three genome-wide association studies

scientific article

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

scientific article

Common variants in genes underlying monogenic hypertension and hypotension and blood pressure in the general population

scientific article

Common variants in the ATP2B1 gene are associated with susceptibility to hypertension: the Japanese Millennium Genome Project

scientific article published on 04 October 2010

Common variants near MC4R are associated with fat mass, weight and risk of obesity

scientific article

Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration

scientific article published on 30 July 2011

Comparison of single and combination diuretics on glucose tolerance (PATHWAY-3): protocol for a randomised double-blind trial in patients with essential hypertension

scientific article

Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies

scientific article

Controversies Surrounding Renal Denervation: Lessons Learned From Real-World Experience in Two United Kingdom Centers

scientific article

Coronary-Heart-Disease-Associated Genetic Variant at the COL4A1/COL4A2 Locus Affects COL4A1/COL4A2 Expression, Vascular Cell Survival, Atherosclerotic Plaque Stability and Risk of Myocardial Infarction

scientific article

Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution.

scientific article published on 27 July 2009

Correction: Population Genomics of Cardiometabolic Traits: Design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium.

scientific article published on 24 September 2013

Cost-effectiveness of options for the diagnosis of high blood pressure in primary care: a modelling study

scientific article

Debrisoquine-type genetic polymorphism differences in medifoxamine pharmacokinetics

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Dietary nitrate provides sustained blood pressure lowering in hypertensive patients: a randomized, phase 2, double-blind, placebo-controlled study

scientific article

Differences between disease-associated endoplasmic reticulum aminopeptidase 1 (ERAP1) isoforms in cellular expression, interactions with tumour necrosis factor receptor 1 (TNF-R1) and regulation by cytokines

scientific article

Directional dominance on stature and cognition in diverse human populations

scientific article published in July 2015

Discovery of novel heart rate-associated loci using the Exome Chip

scientific article

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

scientific article published on 23 November 2020

ERRATUM: Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

article by Matthew B. Lanktree et al published June 2012 in American Journal of Human Genetics

Effect of amiloride, or amiloride plus hydrochlorothiazide, versus hydrochlorothiazide on glucose tolerance and blood pressure (PATHWAY-3): a parallel-group, double-blind randomised phase 4 trial

scientific article published on 16 October 2015

Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals

scientific article published on 01 June 2019

Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations

scientific article

Endocrine and haemodynamic changes in resistant hypertension, and blood pressure responses to spironolactone or amiloride: the PATHWAY-2 mechanisms substudies.

scientific article

Endothelial C-type natriuretic peptide maintains vascular homeostasis

scientific article

Enhanced vasodilator activity of nitrite in hypertension: critical role for erythrocytic xanthine oxidoreductase and translational potential

scientific article

Erratum to “Evolution, essential hypertension and the high arterial pressures in certain athletic breeds of dogs” [The Veterinary Journal 188 (2011) 125–127]

scholarly article published in The Veterinary Journal

Erratum: KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron

article

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article published in November 2011

Ethnic differences in blood pressure response to first and second-line antihypertensive therapies in patients randomized in the ASCOT Trial

scientific article published on 19 August 2010

Ethnic variations in response to a statin (EVIREST).

scientific article published in August 2001

Evaluation of cardiovascular risk equations using the ASCOT cohort

scientific article published in August 2001

Evaluation of the Angiotensinogen Locus in Human Essential Hypertension

article

Evolution, essential hypertension and the high arterial pressures in certain athletic breeds of dogs

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

article by Jason Flannick et al published 22 May 2019 in Nature

Exome-wide association study of plasma lipids in >300,000 individuals

scientific article published on 30 October 2017

Exploring hypertension genome-wide association studies findings and impact on pathophysiology, pathways, and pharmacogenetics

scientific article published on 06 February 2015

Extracellular volume quantification in isolated hypertension - changes at the detectable limits?

scientific article

Functional analyses of coronary artery disease associated variation on chromosome 9p21 in vascular smooth muscle cells

scientific article

Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip

scientific article

Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci

scientific article published on 20 February 2014

Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci

scientific article published on 05 May 2020

Genes for blood pressure: an opportunity to understand hypertension

scientific article published on 9 January 2013

Genes for common diseases.

scientific article published on January 2001

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic and molecular aspects of hypertension

scientific article published on March 2015

Genetic association analysis of inositol polyphosphate phosphatase-like 1 (INPPL1, SHIP2) variants with essential hypertension

scientific article published on 8 June 2007

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

scientific article

Genetic evidence of assortative mating in humans

article

Genetic loci influencing kidney function and chronic kidney disease

scientific article

Genetic mechanisms of critical illness in Covid-19

scientific article published on 11 December 2020

Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials

scientific article

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genetic variants in PPARGC1B and CNTN4 are associated with thromboxane A2 formation and with cardiovascular event free survival in the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT).

scientific article published on 8 December 2017

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Genome-wide analysis of blood pressure variability and ischemic stroke

scientific article

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

scientific article published in February 2013

Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits

scientific article published on 24 January 2019

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

scientific article published in June 2009

Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia

scientific article

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

scientific article published on 16 October 2011

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

scientific article

Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci

scientific article

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

scientific article

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

scientific article

Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension

scientific article

Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a)

scientific article

Genome-wide association study of survival from sepsis due to pneumonia: an observational cohort study

scientific article

Genome-wide mapping of human loci for essential hypertension

scientific article

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide scan identifies CDH13 as a novel susceptibility locus contributing to blood pressure determination in two European populations

scientific article published on 20 March 2009

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

scientific article

Genomewide association study using a high-density single nucleotide polymorphism array and case-control design identifies a novel essential hypertension susceptibility locus in the promoter region of endothelial NO synthase

scientific article published on 19 December 2011

Glutathione S-transferase variants and hypertension

scientific article published in July 2008

Haplotypes of the ??2-adrenergic receptor gene are associated with essential hypertension in a Singaporean Chinese population

article

Haplotypes of the WNK1 gene associate with blood pressure variation in a severely hypertensive population from the British Genetics of Hypertension study

article

Home blood pressure monitoring: new evidence for an expanded role

scientific article published on 21 January 2014

Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article

Hypertension

scientific article published in The Lancet

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

scientific article published on 14 April 2013

Impact of amlodipine-based therapy among older and younger patients in the Anglo-Scandinavian Cardiac Outcomes Trial−Blood Pressure Lowering Arm (ASCOT-BPLA)

Impact of atorvastatin among older and younger patients in the Anglo-Scandinavian Cardiac Outcomes Trial Lipid-Lowering Arm

Increased NBCn1 expression, Na+/HCO3- co-transport and intracellular pH in human vascular smooth muscle cells with a risk allele for hypertension

scientific article

Increased Support for Linkage of a Novel Locus on Chromosome 5q13 for Essential Hypertension in the British Genetics of Hypertension Study

article

Indomethacin and protein binding of methotrexate

scientific article published in July 1992

Influence of matrix metalloproteinase-12 on fibrinogen level

scientific article published on 11 November 2011

Information capture using SNPs from HapMap and whole-genome chips differs in a sample of inflammatory and cardiovascular gene-centric regions from genome-wide estimates

scientific article published on 25 September 2007

Joint UK societies' 2014 consensus statement on renal denervation for resistant hypertension

scientific article

KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron

scientific article

Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci.

scientific article

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

scientific article

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci

scientific article

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci

scientific article

Linkage analysis using co-phenotypes in the BRIGHT study reveals novel potential susceptibility loci for hypertension

scientific article

Linkage of the Angiotensinogen Gene to Essential Hypertension

article

Linkage of the angiotensinogen gene locus to human essential hypertension in African Caribbeans

scientific article published on August 1995

Loci influencing blood pressure identified using a cardiovascular gene-centric array

scientific article published on 8 January 2013

Loci influencing blood pressure identified using a cardiovascular gene-centric array.

scientific article

Management of hypertension: summary of NICE guidance

scientific article published on 25 August 2011

Medical training in the UK: sleepwalking to disaster

scientific article

Mendelian randomisation analyses find pulmonary factors mediate the effect of height on coronary artery disease

scientific article published on 27 March 2019

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

scientific article

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations

scientific article published in June 2009

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

scientific article

Meta-analysis of genome-wide association studies of HDL cholesterol response to statins

scientific article

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

scientific article published on 07 January 2019

Modernising Medical Careers, Medical Training Application Service, and the Postgraduate Medical Education and Training Board: time for the emperors to don their clothes

scientific article published in The Lancet

Modulation of genetic associations with serum urate levels by body-mass-index in humans

scientific article

Monotherapy versus dual therapy for the initial treatment of hypertension (PATHWAY-1): a randomised double-blind controlled trial

scientific article

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

scientific article published on 21 May 2020

Multiple genetic variants explain measurable variance in type 2 diabetes-related traits in Pakistanis

scientific article

Mutations in the TGF-β repressor SKI cause Shprintzen-Goldberg syndrome with aortic aneurysm

scientific article published on 30 September 2012

NICE hypertension guideline 2011: evidence based evolution

scientific article published on 13 January 2012

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

scientific article published in October 2017

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

scientific article

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

scientific article published on 18 June 2018

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Novel polymorphic AluYb8 insertion in the WNK1 gene is associated with blood pressure variation in Europeans

scientific article published on 10 May 2011

Nuclear-mitochondrial DNA segments resemble paternally inherited mitochondrial DNA in humans

scientific article published on 08 April 2020

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

PanelApp crowdsources expert knowledge to establish consensus diagnostic gene panels

scientific article published on 01 November 2019

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

scientific article

Pharmacogenomics in the UK National Health Service: opportunities and challenges

scientific article published on 29 October 2020

Phenotypic consequences of variation across the aldosterone synthase and 11-beta hydroxylase locus in a hypertensive cohort: data from the MRC BRIGHT Study.

scientific article

Polymorphic variation in the 11beta-hydroxylase gene associates with reduced 11-hydroxylase efficiency

scientific article published on 30 October 2006

Polymorphisms in the WNK1 gene are associated with blood pressure variation and urinary potassium excretion

scientific article

Population genomics of cardiometabolic traits: design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium

scientific article (publication date: 2013)

Possible association but no linkage of the HSD11B2 gene encoding the kidney isozyme of 11beta-hydroxysteroid dehydrogenase to hypertension in Black people

article

Potential synergy between lipid-lowering and blood-pressure-lowering in the Anglo-Scandinavian Cardiac Outcomes Trial

article by P. Sever et al published 4 December 2006 in European Heart Journal

Predicting deleterious nsSNPs: an analysis of sequence and structural attributes

scientific article

Prevention And Treatment of Hypertension With Algorithm-based therapy (PATHWAY) number 2: protocol for a randomised crossover trial to determine optimal treatment for drug-resistant hypertension

scientific article

Prevention of Coronary and Stroke Events with Atorvastatin in Hypertensive Patients who have Average or Lower-than-Average Cholesterol Concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial— Lipid Lowering Arm (ASCOT-LLA)

scientific article

Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (A

scientific article

Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial--Lipid Lowering Arm (ASCOT-LLA): a multicentre ra

scientific article

Progress in determining the genes for hypertension, insulin resistance, and dyslipidemia.

scientific article published on September 1997

Protein interaction networks associated with cardiovascular disease and cancer: exploring the effect of bias on shared network properties

scientific article

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 22 December 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Pseudoexon activation as a novel mechanism for disease resulting in atypical growth-hormone insensitivity

scientific article

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 01 July 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

scientific article published on 16 March 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

scientific article

Randomised, double-blind, placebo-controlled study investigating the effects of inorganic nitrate on vascular function, platelet reactivity and restenosis in stable angina: protocol of the NITRATE-OCT study

scientific article published on 20 December 2016

Rapid diagnosis of testicular choriocarcinoma by urinary pregnancy tests

scientific article published in The Lancet

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Rationale, design, methods and baseline demography of participants of the Anglo-Scandinavian Cardiac Outcomes Trial. ASCOT investigators

scientific article

Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document

article by Giuseppe Mancia et al published November 2009 in Journal of Hypertension

Recent advances in the identification of genes for human hypertension

scientific article

Reduction in cardiovascular events with atorvastatin in 2,532 patients with type 2 diabetes: Anglo-Scandinavian Cardiac Outcomes Trial--lipid-lowering arm (ASCOT-LLA).

scientific article

Renal artery sympathetic denervation: observations from the UK experience.

scientific article

Replication of the five novel loci for uric acid concentrations and potential mediating mechanisms

scientific article

Role of blood pressure and other variables in the differential cardiovascular event rates noted in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA).

scientific article

SLC2A9 is a high-capacity urate transporter in humans

scientific article

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

scientific article

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

scientific article

Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial

scientific article

Status and future of genomics in blood pressure

Targeting 160 candidate genes for blood pressure regulation with a genome-wide genotyping array

scientific article

Testing the role of predicted gene knockouts in human anthropometric trait variation

scientific article

The Anglo-Scandinavian Cardiac Outcomes Trial lipid lowering arm: extended observations 2 years after trial closure

scientific article published on 5 January 2008

The Anglo-Scandinavian Cardiac Outcomes Trial: blood pressure-lowering limb: effects in patients with type II diabetes

scientific article

The angiotensin converting enzyme gene in cardiovascular disease.

scientific article published on September 1995

The biological impact of blood pressure-associated genetic variants in the natriuretic peptide receptor C gene on human vascular smooth muscle.

scientific article published on 10 October 2017

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

The novel genetic variant predisposing to coronary artery disease in the region of the PSRC1 and CELSR2 genes on chromosome 1 associates with serum cholesterol

scientific article published on 23 July 2008

The power of genetic diversity in genome-wide association studies of lipids

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

scientific article published on 12 September 2016

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals

scientific article published on 21 December 2018

Two-dimensional genome-scan identifies novel epistatic loci for essential hypertension

article