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List of works by Gordon B. Mills

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The Cancer Genome Atlas Pan-Cancer analysis project

scientific article
The somatic genomic landscape of glioblastoma

scientific article
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article
Integrated genomic characterization of endometrial carcinoma

scientific article published on May 2, 2013
Next-generation characterization of the Cancer Cell Line Encyclopedia

scientific article published on 08 May 2019
Use of proteomic patterns in serum to identify ovarian cancer

scientific article
Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays

scientific article
A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer

scientific article
Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer

scientific article
Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

scientific journal article
Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth

scientific article
Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling

scientific article
The biology of ovarian cancer: new opportunities for translation

scientific article
Rethinking ovarian cancer: recommendations for improving outcomes

scientific article
Inferring tumour purity and stromal and immune cell admixture from expression data

scientific article
Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin

scientific article
An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer

scientific article published on August 2008
The emerging role of lysophosphatidic acid in cancer

scientific article (publication date: August 2003)
PIK3CA is implicated as an oncogene in ovarian cancer

scientific article published in January 1999
Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics

scientific article (publication date: 15 May 2009)
Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A

scientific article
Phosphorylation of beta-catenin by AKT promotes beta-catenin transcriptional activity

scientific article published on 7 February 2007
Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells

scientific article published on October 2006
Derailed endocytosis: an emerging feature of cancer

scientific article
An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance

scientific article published on 22 October 2012
Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production

scientific article
ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

scientific article published on 20 January 2008
Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma

scientific article published on 4 November 2015
Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer

scientific article
ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS

scientific article
AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer

scientific article
Rab25 associates with alpha5beta1 integrin to promote invasive migration in 3D microenvironments

scientific article
Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1.

scientific article published on 6 September 2012
Subtype and pathway specific responses to anticancer compounds in breast cancer

scientific article published on 14 October 2011
Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

scientific article published in Nature
A module of negative feedback regulators defines growth factor signaling

scientific article published on 25 February 2007
Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts

scientific article
Frequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkers

scientific article
The RAB25 small GTPase determines aggressiveness of ovarian and breast cancers

scientific article
High frequency of PIK3R1 and PIK3R2 mutations in endometrial cancer elucidates a novel mechanism for regulation of PTEN protein stability

scientific article
Comprehensive Genomic Analysis Identifies Novel Subtypes and Targets of Triple-Negative Breast Cancer

scientific article published on September 10, 2014
Hyperactivation of phosphatidylinositol-3 kinase promotes escape from hormone dependence in estrogen receptor-positive human breast cancer

scientific article
Comprehensive Characterization of Cancer Driver Genes and Mutations

scientific article published in April 2018
Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages

scientific article published on March 2006
Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors.

scientific article
Modeling precision treatment of breast cancer

scientific article published on January 2013
Inhibition of PI3K/mTOR leads to adaptive resistance in matrix-attached cancer cells

scientific article published in February 2012
Comprehensive Genomic Characterization of Long Non-coding RNAs across Human Cancers.

scientific article published on October 2015
PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells.

scientific article
A pan-cancer proteomic perspective on The Cancer Genome Atlas.

scientific article

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