List of works - Sekar Kathiresan

Analysis of protein-coding genetic variation in 60,706 humans

scientific article (publication date: 17 August 2016)

Biological, clinical and population relevance of 95 loci for blood lipids

scientific article

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

scientific article (publication date: June 2007)

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

scientific article (publication date: November 2010)

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article

Discovery and refinement of loci associated with lipid levels

scientific article

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

scientific article

Age-related clonal hematopoiesis associated with adverse outcomes

scientific article

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

scientific article

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

scientific article

Common variants at 30 loci contribute to polygenic dyslipidemia

scientific article

Large-scale association analysis identifies new risk loci for coronary artery disease

scientific article published on 02 December 2012

Genome-wide association study identifies eight loci associated with blood pressure

scientific article (publication date: June 2009)

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

scientific article

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

scientific article

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

scientific article

Testing for an unusual distribution of rare variants

scientific article

Identification of seven loci affecting mean telomere length and their association with disease

scientific article published on April 2013

Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress: the Framingham Heart Study

scientific article (publication date: 11 September 2007)

Polymorphisms associated with cholesterol and risk of cardiovascular events

scientific article

The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits

scientific article

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

scientific article

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies

scientific article

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Searching for missing heritability: designing rare variant association studies

scientific article published on 17 January 2014

Meta-analysis identifies six new susceptibility loci for atrial fibrillation

scientific article published on 29 April 2012

Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations

article by Amit V Khera et al published September 2018 in Nature Genetics

New susceptibility locus for coronary artery disease on chromosome 3q22.3.

scientific article published on 08 February 2009

Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

scientific article

Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia

scientific journal article

Exome sequencing, ANGPTL3 mutations, and familial combined hypolipidemia

scientific article

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies

scientific article

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

scientific article

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways

scientific article

Association of common variants in NPPA and NPPB with circulating natriuretic peptides and blood pressure

scientific article published on 15 February 2009

Genetic associations with valvular calcification and aortic stenosis

scientific article published on February 2013

Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

scientific article

A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses

scientific article

FTO genotype is associated with phenotypic variability of body mass index

scientific article published on 16 September 2012

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

scientific article published on 24 September 2014

Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project

scientific article

Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis

scientific article

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

scientific article

Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension

scientific article

Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease

scientific article

Best practices and joint calling of the HumanExome BeadChip: the CHARGE Consortium

scientific article

List of works by Sekar Kathiresan

Analysis of protein-coding genetic variation in 60,706 humans

Biological, clinical and population relevance of 95 loci for blood lipids

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

Genetic studies of body mass index yield new insights for obesity biology

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Hundreds of variants clustered in genomic loci and biological pathways affect human height

Discovery and refinement of loci associated with lipid levels

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

Age-related clonal hematopoiesis associated with adverse outcomes

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

Common variants at 30 loci contribute to polygenic dyslipidemia

Large-scale association analysis identifies new risk loci for coronary artery disease

Genome-wide association study identifies eight loci associated with blood pressure

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

Testing for an unusual distribution of rare variants

Identification of seven loci affecting mean telomere length and their association with disease

Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress: the Framingham Heart Study

Polymorphisms associated with cholesterol and risk of cardiovascular events

The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

Common variants associated with plasma triglycerides and risk for coronary artery disease

Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Searching for missing heritability: designing rare variant association studies

Meta-analysis identifies six new susceptibility loci for atrial fibrillation

Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations

New susceptibility locus for coronary artery disease on chromosome 3q22.3.

Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia

Exome sequencing, ANGPTL3 mutations, and familial combined hypolipidemia

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways

Association of common variants in NPPA and NPPB with circulating natriuretic peptides and blood pressure

Genetic associations with valvular calcification and aortic stenosis

Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses

FTO genotype is associated with phenotypic variability of body mass index

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project

Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension

Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease

Best practices and joint calling of the HumanExome BeadChip: the CHARGE Consortium