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List of works by Virginia Man-Yee Lee

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Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration

scientific article
TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions

scientific article published in July 2007
GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease

scientific article
Plasma multianalyte profiling in mild cognitive impairment and Alzheimer disease

scientific article
Unique pathological tau conformers from Alzheimer's brains transmit tau pathology in nontransgenic mice

scientific article published on 17 October 2016
Pathological Tau Strains from Human Brains Recapitulate the Diversity of Tauopathies in Nontransgenic Mouse Brain

scientific article
Nosology of Parkinson's disease: looking for the way out of a quagmire

scientific article
Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers

scientific article published on 28 February 2017
Cerebrospinal fluid neurogranin concentration in neurodegeneration: relation to clinical phenotypes and neuropathology

scientific article published on 26 April 2018
Association of Cerebrospinal Fluid Neurofilament Light Protein Levels With Cognition in Patients With Dementia, Motor Neuron Disease, and Movement Disorders

scientific article published on 01 March 2019
Effects of gamma-secretase inhibition on the amyloid beta isoform pattern in a mouse model of Alzheimer's disease

scientific article
Selective Motor Neuron Resistance and Recovery in a New Inducible Mouse Model of TDP-43 Proteinopathy.

scientific article
Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism

scientific article
TFEB enhances astroglial uptake of extracellular tau species and reduces tau spreading.

scientific article published on 14 August 2018
Characterization of tau pathologies in gray and white matter of Guam parkinsonism-dementia complex

scientific article
Sex-specific genetic predictors of Alzheimer's disease biomarkers

scientific article published on 02 July 2018
Elevated CSF GAP-43 is Alzheimer's disease specific and associated with tau and amyloid pathology

scientific article published on 12 October 2018
LRRK2 activity does not dramatically alter α-synuclein pathology in primary neurons.

scientific article
Unbiased Proteomics of Early Lewy Body Formation Model Implicates Active Microtubule Affinity-Regulating Kinases (MARKs) in Synucleinopathies

scientific article published on 17 May 2017
α-Synuclein (αSyn) Preformed Fibrils Induce Endogenous αSyn Aggregation, Compromise Synaptic Activity and Enhance Synapse Loss in Cultured Excitatory Hippocampal Neurons

scientific article published on 29 April 2019
Alzheimer's disease tau is a prominent pathology in LRRK2 Parkinson's disease

scientific article published on 16 November 2019
Identifying amyloid pathology-related cerebrospinal fluid biomarkers for Alzheimer's disease in a multicohort study

scientific article published in September 2015
Protein transmission in neurodegenerative disease

scientific article published on 23 March 2020
Measurements of auto-antibodies to α-synuclein in the serum and cerebral spinal fluids of patients with Parkinson's disease.

scientific article published on 3 March 2018
A "Clickable" Photoconvertible Small Fluorescent Molecule as a Minimalist Probe for Tracking Individual Biomolecule Complexes

scientific article published on 28 January 2019
GFP-Mutant Human Tau Transgenic Mice Develop Tauopathy Following CNS Injections of Alzheimer's Brain-Derived Pathological Tau or Synthetic Mutant Human Tau Fibrils.

scientific article
TRIM11 protects against tauopathies and is down-regulated in Alzheimer’s disease

scientific article published on 27 July 2023
A microtubule stabilizer ameliorates protein pathogenesis and neurodegeneration in mouse models of repetitive traumatic brain injury

scientific article published on 13 September 2023
Glucocerebrosidase activity and lipid levels are related to protein pathologies in Parkinson’s disease

scientific article published on 11 May 2023
α-Synuclein aggregates amplified from patient-derived Lewy bodies recapitulate Lewy body diseases in mice

scientific article published on 28 October 2023
Neuronal activity modulates alpha-synuclein aggregation and spreading in organotypic brain slice cultures and in vivo

scientific article published on 06 October 2020
AD-linked R47H-TREM2mutation induces disease-enhancing microglial states via AKT hyperactivation

scientific article published in December 2021

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