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List of works by Renger Witkamp

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Metabolomics in the context of systems biology: bridging traditional Chinese medicine and molecular pharmacology

scientific article
A combination of proteomics, principal component analysis and transcriptomics is a powerful tool for the identification of biomarkers for macrophage maturation in the U937 cell line.

scientific article published in April 2004
Vitamin D: do we get enough? A discussion between vitamin D experts in order to make a step towards the harmonisation of dietary reference intakes for vitamin D across Europe.

scientific article published on 11 December 2012
Fish oil and inflammatory status alter the n-3 to n-6 balance of the endocannabinoid and oxylipin metabolomes in mouse plasma and tissues

scientific article
Participation of β-Adrenergic Receptors on Macrophages in Modulation of LPS-Induced Cytokine Release

scientific article published on 01 January 1999
Suppression of Cytochrome P450- and UDP Glucuronosyl Transferase-Dependent Enzyme Activities by Proinflammatory Cytokines and Possible Role of Nitric Oxide in Primary Cultures of Pig Hepatocytes

article
Docosahexaenoic acid and eicosapentaenoic acid are converted by 3T3-L1 adipocytes to N-acyl ethanolamines with anti-inflammatory properties.

scientific article published on 27 June 2010
The beta-adrenoceptor agonist clenbuterol is a potent inhibitor of the LPS-induced production of TNF-alpha and IL-6 in vitro and in vivo

scientific article published on September 1999
Direct cell-to-cell contact between Kupffer cells and hepatocytes augments endotoxin-induced hepatic injury

scientific article published on 01 April 2001
The endocannabinoid system and appetite: relevance for food reward

scientific article
Congener specific PCB and polychlorinated camphene (toxaphene) levels in Svalbard ringed seals (Phoca hispida) in relation to sex, age, condition and cytochrome P450 enzyme activity

scientific article published in May 1998
Behavioural changes are a major contributing factor in the reduction of sarcopenia in caloric-restricted ageing mice

scientific article
Development and validation of a quantitative method for the determination of 12 endocannabinoids and related compounds in human plasma using liquid chromatography–tandem mass spectrometry

article
The ethanolamide metabolite of DHA, docosahexaenoylethanolamine, shows immunomodulating effects in mouse peritoneal and RAW264.7 macrophages: evidence for a new link between fish oil and inflammation

scientific article published on 4 February 2011
Xanthohumol from hop (Humulus lupulus L.) is an efficient inhibitor of monocyte chemoattractant protein-1 and tumor necrosis factor-alpha release in LPS-stimulated RAW 264.7 mouse macrophages and U937 human monocytes

scientific article
Characterization of anti-inflammatory compounds using transcriptomics, proteomics, and metabolomics in combination with multivariate data analysis.

scientific article published in November 2004
26th Hohenheim Consensus Conference, September 11, 2010 Scientific substantiation of health claims: evidence-based nutrition

scientific article
Plasma anandamide and other N-acylethanolamines are correlated with their corresponding free fatty acid levels under both fasting and non-fasting conditions in women

scientific article
Current and Future Drug Targets in Weight Management

scientific article published on December 23, 2010
Characterization of cytochrome P450 isoenzymes in primary cultures of pig hepatocytes

scientific article published in December 1998
N-Acyl amines of docosahexaenoic acid and other n-3 polyunsatured fatty acids - from fishy endocannabinoids to potential leads

scientific article
Endotoxin-induced liver damage in rats is minimized by beta 2-adrenoceptor stimulation

scientific article published on 16 February 2004
Palmitoylethanolamide: A Natural Body-Own Anti-Inflammatory Agent, Effective and Safe against Influenza and Common Cold

scientific article
Cytochromes and cytokines: changes in drug disposition in animals during an acute phase response: a mini-review

scientific article
Medication-related fall incidents in an older, ambulant population: the B-PROOF study

scientific article published on December 2014
Presence, formation and putative biological activities of N-acyl serotonins, a novel class of fatty-acid derived mediators, in the intestinal tract.

scientific article
Pharma-nutrition interface: the gap is narrowing

scientific article
Vitamin D, Inflammation, and Colorectal Cancer Progression: A Review of Mechanistic Studies and Future Directions for Epidemiological Studies

scientific article published on 22 September 2015
Time-dependent effect of in vivo inflammation on eicosanoid and endocannabinoid levels in plasma, liver, ileum and adipose tissue in C57BL/6 mice fed a fish-oil diet

scientific article published on 09 April 2012
Fish oil LC-PUFAs do not affect blood coagulation parameters and bleeding manifestations: Analysis of 8 clinical studies with selected patient groups on omega-3-enriched medical nutrition.

scientific article published on 29 March 2017
Measurement of palmitoylethanolamide and other N-acylethanolamines during physiological and pathological conditions.

scientific article published on February 2013
Tolerability and safety of Souvenaid in patients with mild Alzheimer's disease: results of multi-center, 24-week, open-label extension study

scientific article published on January 2015
Differential effect of pentoxifylline on lipopolysaccharide-induced downregulation of cytochrome p450

scientific article published on 01 October 1996
Signal transduction in inflammatory processes, current and future therapeutic targets: a mini review.

scientific article
Development of an Androgen Reporter Gene Assay (AR-LUX) Utilizing a Human Cell Line with an Endogenously Regulated Androgen Receptor

scientific article published on November 1, 2001
Inhibition of COX-2-mediated eicosanoid production plays a major role in the anti-inflammatory effects of the endocannabinoid N-docosahexaenoylethanolamine (DHEA) in macrophages

scientific article published on 23 September 2014
Unheated Cannabis sativa extracts and its major compound THC-acid have potential immuno-modulating properties not mediated by CB1 and CB2 receptor coupled pathways.

scientific article
Tiamulin selectively inhibits oxidative hepatic steroid and drug metabolism in vitro in the pig

scientific article published on 01 August 1994
Cross-species comparison of genes related to nutrient sensing mechanisms expressed along the intestine

scientific article
Review article: the role of gastrointestinal hormones in the treatment of delayed gastric emptying in critically ill patients

scientific article published on 23 July 2013
Differences in food intake of tumour-bearing cachectic mice are associated with hypothalamic serotonin signalling

scientific article
Beta-adrenergic receptor agonists induce the release of granulocyte chemotactic protein-2, oncostatin M, and vascular endothelial growth factor from macrophages.

scientific article
Comparative analyses of seeds of wild fruits of Rubus and Sambucus species from Southern Italy: fatty acid composition of the oil, total phenolic content, antioxidant and anti-inflammatory properties of the methanolic extracts

scientific article published on 15 November 2012
In vitro complex formation and inhibition of hepatic cytochrome P450 activity by different macrolides and tiamulin in goats and cattle

scientific article published on February 1999
Liquid chromatography-tandem mass spectrometry analysis of free and esterified fatty acid N-acyl ethanolamines in plasma and blood cells

scientific article published on 29 November 2012
Alterations in total and high-molecular-weight adiponectin after 3 weeks of moderate alcohol consumption in premenopausal women

scientific article published on 24 February 2011
Moderate alcohol consumption alters both leucocyte gene expression profiles and circulating proteins related to immune response and lipid metabolism in men

article
Fatty acids, endocannabinoids and inflammation

scientific article
Nutrient Intake by Ultramarathon Runners: Can They Meet Recommendations?

scientific article published on 26 March 2015
Commentary: "A systems view on the future of medicine: inspiration from Chinese medicine?".

scientific article

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