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List of works by Jeremy K. Nicholson

-Omics dreams of personalized healthcare

scientific article published on 01 September 2006

19F NMR spectroscopic investigation into the absorption and metabolism of 3-trifluoromethylaniline in Eisenia veneta

scientific article

19F and 1H magnetic resonance strategies for metabolic studies on fluorinated xenobiotics: Application to flurbiprofen [2-(2-fluoro-4-biphenylyl)propionic acid]

scientific article published on 01 January 1990

19F-NMR and directly coupled 19F/1H-HPLC-NMR spectroscopic investigations of the metabolism of the model ecotoxin 3-trifluoromethylaniline in the earthworm species Eisenia veneta

scientific article published in June 2002

19F-NMR and directly coupled HPLC-NMR-MS investigations into the metabolism of 2-bromo-4- trifluoromethylaniline in rat: a urinary excretion balance study without the use of radiolabelling ⬇️

scientific article published on April 1, 1998

1H HR-MAS NMR spectroscopy of tumor-induced local metabolic "field-effects" enables colorectal cancer staging and prognostication

article

1H NMR Global Metabolic Phenotyping of Acute Pancreatitis in the Emergency Unit

scientific article published on 08 October 2014

1H NMR and UPLC-MS(E) statistical heterospectroscopy: characterization of drug metabolites (xenometabolome) in epidemiological studies

scientific article

1H NMR and UPLC-MSEStatistical Heterospectroscopy: Characterization of Drug Metabolites (Xenometabolome) in Epidemiological Studies

scientific article published in 2008

1H NMR spectroscopic and histopathological studies on propyleneimine-induced renal papillary necrosis in the rat and the multimammate desert mouse (Mastomys natalensis).

scientific article published on February 1997

1H NMR spectroscopy-based interventional metabolic phenotyping: a cohort study of rheumatoid arthritis patients.

scientific article published on September 2010

1H and 2H NMR spectroscopic studies on the metabolism and biochemical effects of 2-bromoethanamine in the rat

article

1H-NMR spectroscopy of biofluids and the investigation of xenobiotic-induced changes in liver biochemistry

scientific article published in January 1990

2-Furoylglycine as a Candidate Biomarker of Coffee Consumption

scientific article published on 11 September 2015

2.7.5. HPLC/NMR and related hyphenated NMR methods

600 MHz 1H-NMR spectroscopy of human cerebrospinal fluid: effects of sample manipulation and assignment of resonances

scientific article published on August 1993

750 MHz 1H NMR spectroscopy characterisation of the complex metabolic pattern of urine from patients with inborn errors of metabolism: 2-hydroxyglutaric aciduria and maple syrup urine disease

scientific article published on July 1997

750 MHz 1H-NMR spectroscopy of human blood plasma

scientific article published on 01 April 1993

750 MHz HPLC-NMR spectroscopic identification of rat microsomal metabolites of phenoxypyridines

scientific article published on 01 November 1997

750 MHz HPLC−NMR Spectroscopic Studies on the Separation and Characterization of the Positional Isomers of the Glucuronides of 6,11-Dihydro-11- oxodibenz[b,e]oxepin-2-acetic Acid

scientific article published on 01 January 1996

750-MHz directly coupled HPLC-NMR: Application for the sequential characterization of the positional isomers and anomers of 2-, 3-, and 4-fluorobenzoic acid glucuronides in equilibrium mixtures

article published in 1995

A Metabolic Entropy Approach for Measurements of Systemic Metabolic Disruptions in Patho-Physiological States

scientific article published on 01 July 2010

A Metabolite Array Technology for Precision Medicine

scientific article published in 2021

A QSAR investigation of dermal and respiratory chemical sensitizers based on computational chemistry properties

scientific article published on 01 July 2009

A Unified Conceptual Framework for Metabolic Phenotyping in Diagnosis and Prognosis

scientific article published on 09 September 2019

A comparison of collision cross section values obtained via travelling wave ion mobility-mass spectrometry and ultra high performance liquid chromatography-ion mobility-mass spectrometry: Application to the characterisation of metabolites in rat uri

scientific article published on 27 June 2019

A comparison of quantitative NMR and radiolabelling studies of the metabolism and excretion of Statil (3-(4-bromo-2-fluorobenzyl)-4-oxo-3H-phthalazin-1-ylacetic acid) in the rat.

scientific article published in April 2002

A comparison of self-reported analgesic use and detection of urinary ibuprofen and acetaminophen metabolites by means of metabonomics: the INTERMAP Study

scientific article published on 5 January 2012

A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection

scientific article

A metabolic phenotyping approach to understanding relationships between metabolic syndrome and breast tumour responses to chemotherapy

scientific article published on 4 August 2011

A metabolic system-wide characterisation of the pig: a model for human physiology

article

A metabonomic investigation of hepatotoxicity using diffusion-edited 1H NMR spectroscopy of blood serum

scientific article published in July 2003

A metabonomic strategy for the detection of the metabolic effects of chamomile (Matricaria recutita L.) ingestion

scientific article published in January 2005

A multiplexed targeted assay for high-throughput quantitative analysis of serum methylamines by ultra performance liquid chromatography coupled to high resolution mass spectrometry

scientific article published on 29 March 2016

A novel LC-MS approach for the detection of metabolites in DMPK studies.

scientific article published on October 2010

A novel methodology for in vivo endoscopic phenotyping of colorectal cancer based on real-time analysis of the mucosal lipidome: a prospective observational study of the iKnife

scientific article

A pattern recognition approach to the comparison of PMR and clinical chemical data for classification of nephrotoxicity.

scientific article

A prospective analysis of mucosal microbiome-metabonome interactions in colorectal cancer using a combined MAS 1HNMR and metataxonomic strategy

scientific article published on 21 August 2017

A prospective cohort analysis of gut microbial co-metabolism in Alaska Native and rural African people at high and low risk of colorectal cancer

scientific article published on 01 February 2020

A rapid simple approach to screening pharmaceutical products using ultra-performance LC coupled to time-of-flight mass spectrometry and pattern recognition

scientific article published in March 2008

A simultaneous exploratory and quantitative amino acid and biogenic amine metabolic profiling platform for rapid disease phenotyping via UPLC-QToF-MS

scientific article published on 07 November 2020

A study of metabolic compartmentation in the rat heart and cardiac mitochondria using high-resolution magic angle spinning 1H NMR spectroscopy.

scientific article

A study of the metabolism of dimethylformamide in the rat by high resolution proton NMR spectroscopy

scientific article published on 01 January 1989

A top-down systems biology view of microbiome-mammalian metabolic interactions in a mouse model

scientific article

A two-way interaction between methotrexate and the gut microbiota of male Sprague Dawley rats

scientific article published on 16 June 2020

A validated UPLC-MS/MS assay for the quantification of amino acids and biogenic amines in rat urine

scientific article published on 29 December 2018

APPLICATION OF HIGH RESOLUTION H-NMR SPECTROSCOPY TO THE DETECTION OF PENICILLAMINE AND ITS METABOLITES IN HUMAN URINE

scientific article published on 01 January 1988

Abnormal lipid profile of dystrophic cardiac tissue as demonstrated by one- and two-dimensional magic-angle spinning (1)H NMR spectroscopy

scientific article published in August 2001

Acute renal failure following accidental cutaneous absorption of phenol: application of NMR urinalysis to monitor the disease process.

scientific article

Addressing the challenge of limited sample volumes inin vitrostudies with capillary-scale microfluidic LC–MS/MS

article

Age and microenvironment outweigh genetic influence on the Zucker rat microbiome

scientific article (publication date: 2014)

An Analytical Pipeline for Quantitative Characterization of Dietary Intake: Application To Assess Grape Intake

article

An NMR study of the metabolic fate of 2-, 3- and 4-fluorobenzyl alcohols in the rat: detection of N-acetylcysteinyl conjugates as minor metabolites in urine

scientific article

An NMR-based metabonomic approach to investigate the biochemical consequences of genetic strain differences: application to the C57BL10J and Alpk:ApfCD mouse

scientific article published on 01 November 2000

An NMR-based metabonomic approach to the investigation of coelomic fluid biochemistry in earthworms under toxic stress.

scientific article published on June 2001

An hypothesis for a mechanism underlying hepatotoxin-induced hypercreatinuria

scientific article published on 5 February 2003

An integrated ceramic, micro-fluidic device for the LC/MS/MS analysis of pharmaceuticals in plasma

scientific article published in July 2015

An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate

scientific article published in October 2006

An integrated metabonomic investigation of acetaminophen toxicity in the mouse using NMR spectroscopy

scientific article published in March 2003

An integrated reverse functional genomic and metabolic approach to understanding orotic acid-induced fatty liver

scientific article published on 13 April 2004

Analysis of biological fluids using 600 MHz proton NMR spectroscopy: Application of homonuclear two-dimensional J-resolved spectroscopy to urine and blood plasma for spectral simplification and assignment

article

Analysis of polar urinary metabolites for metabolic phenotyping using supercritical fluid chromatography and mass spectrometry

scientific article published on 19 April 2016

Analysis of time-related metabolic fluctuations induced by ethionine in the rat.

scientific article published on 30 October 2007

Analytic properties of statistical total correlation spectroscopy based information recovery in 1H NMR metabolic data sets

scientific article

Analytical reproducibility in (1)H NMR-based metabonomic urinalysis

scientific article

Analytical technologies for metabonomics and metabolomics, and multi-omic information recovery

article

Application of (1)H- and (19)F-NMR spectroscopy in the investigation of the urinary and biliary excretion of 3,5-, 2,4-ditrifluoromethylbenzoic and pentafluorobenzoic acids in rat.

scientific article published in July 2002

Application of Directly Coupled HPLC NMR to Separation and Characterization of Lipoproteins from Human Serum

scientific article published on 01 March 2001

Application of Directly Coupled HPLC-NMR-MS/MS to the Identification of Metabolites of 5-Trifluoromethylpyridone (2-Hydroxy-5-trifluoromethylpyridine) in Hydroponically Grown Plants

article

Application of NMR-based metabolomics to the investigation of salt stress in maize (Zea mays).

scientific article

Application of biofluid 1 H nuclear magnetic resonance-based metabonomic techniques for the analysis of the biochemical effects of dietary isoflavones on human plasma profile

article

Application of chemometrics to 1H NMR spectroscopic data to investigate a relationship between human serum metabolic profiles and hypertension

scientific article

Application of chemometrics to the 1H NMR spectra of apple juices: discrimination between apple varieties

article

Application of directly coupled LC–NMR–MS to the structural elucidation of metabolites of the HIV-1 reverse-transcriptase inhibitor BW935U83

article

Application of directly coupled high performance liquid chromatography-NMR-mass spectometry and 1H NMR spectroscopic studies to the investigation of 2,3-benzofuran metabolism in Sprague-Dawley rats

scientific article published in December 2002

Application of inductively coupled plasma mass spectrometry and high-performance liquid chromatography—with parallel electrospray mass spectrometry to the investigation of the disposition and metabolic fate of 2-, 3- and 4-iodobenzoic acids in the

scientific article published on 01 October 2004

Application of novel solid phase extraction-NMR protocols for metabolic profiling of human urine

scientific article published on 01 August 2019

Application of orthogonal signal correction to minimise the effects of physical and biological variation in high resolution 1H NMR spectra of biofluids

scientific article published in October 2002

Application of the FLIPSY pulse sequence for increased sensitivity in 1H NMR-based metabolic profiling studies

scientific article

Application of the one-dimensional TOCSY pulse sequence in 750 MHz 1H-NMR spectroscopy for assignment of endogenous metabolite resonances in biofluids

scientific article published on 01 May 1994

Assessment of Analytical Reproducibility of1H NMR Spectroscopy Based Metabonomics for Large-Scale Epidemiological Research: the INTERMAP Study

article

Assignment of 1H nuclear magnetic resonance visible polyunsaturated fatty acids in BT4C gliomas undergoing ganciclovir-thymidine kinase gene therapy-induced programmed cell death

scientific article

Assignment of the 750 MHz 1H NMR resonances from a mixture of transacylated ester glucuronic acid conjugates with the aid of oversampling and digital filtering during acquisition

scientific article

Association of Untargeted Urinary Metabolomics and Lung Cancer Risk Among Never-Smoking Women in China

scientific article published on 04 September 2019

Automatic Spectroscopic Data Categorization by Clustering Analysis (ASCLAN): A Data-Driven Approach for Distinguishing Discriminatory Metabolites for Phenotypic Subclasses

scientific article

Automatic alignment of individual peaks in large high-resolution spectral data sets

scientific article

Automatic data reduction and pattern recognition methods for analysis of 1H nuclear magnetic resonance spectra of human urine from normal and pathological states.

scientific article published on August 1994

BASIS: High-performance bioinformatics platform for processing of large-scale mass spectrometry imaging data in chemically augmented histology

scientific article published on 6 March 2018

Bacterial adaptation to the gut environment favors successful colonization: microbial and metabonomic characterization of a simplified microbiota mouse model

scientific article published in November 2011

Bariatric surgery modulates circulating and cardiac metabolites

scientific article published on 26 November 2013

Bidirectional communication between the Aryl hydrocarbon Receptor (AhR) and the microbiome tunes host metabolism

scientific article

Bidirectional correlation of NMR and capillary electrophoresis fingerprints: a new approach to investigating Schistosoma mansoni infection in a mouse model

scientific article published in January 2010

Bile UPLC-MS fingerprinting and bile acid fluxes during human liver transplantation

article

Bile acid profiling and quantification in biofluids using ultra-performance liquid chromatography tandem mass spectrometry

scientific article published in September 2015

Biochemical characterisation of para-aminophenol-induced nephrotoxic lesions in the F344 rat

article

Biochemical characterization of rat intestine development using high-resolution magic-angle-spinning 1H NMR spectroscopy and multivariate data analysis

scientific article published in July 2005

Biochemical classification of kidney carcinoma biopsy samples using magic-angle-spinning 1H nuclear magnetic resonance spectroscopy

article published in 1998

Biofluid 1H NMR-based metabonomic techniques in nutrition research - metabolic effects of dietary isoflavones in humans

scientific article

Broad-Ranging Natural Metabotype Variation Drives Physiological Plasticity in Healthy Control Inbred Rat Strains

scientific article published on 15 March 2011

COMET and the Challenge of Drug Safety Screening

COMET and the challenge of drug safety screening

scientific article published on 25 September 2007

Cadmium and mercury nephrotoxicity

scientific article published in Nature

Cellular acidosis in rodents exposed to cadmium is caused by adaptation of the tissue rather than an early effect of toxicity

scientific article

Cellular environment of metabolites and a metabonomic study of tamoxifen in endometrial cells using gradient high resolution magic angle spinning 1H NMR spectroscopy

scientific article published on January 2003

Cephaloridine-induced nephrotoxicity in the Fischer 344 rat: proton NMR spectroscopic studies of urine and plasma in relation to conventional clinical chemical and histopathological assessments of nephronal damage

scientific article published in January 1992

Cervical intraepithelial neoplasia disease progression is associated with increased vaginal microbiome diversity

scientific article published on 17 November 2015

Characterisation of impurities in bulk drug batches of fluticasone propionate using directly coupled HPLC–NMR spectroscopy and HPLC–MS

scientific article published on 01 December 1997

Characterisation of putative pentose-containing conjugates as minor metabolites of 4-bromoaniline present in the urine of rats following intraperitoneal administration

scientific article published in January 2003

Characterization and quantification of metabolites of racemic ketoprofen excreted in urine following oral administration to man by 1H-NMR spectroscopy, directly coupled HPLC-MS and HPLC-NMR, and circular dichroism

scientific article published in November 2004

Characterization of Metabolites in IntactStreptomyces citricolorCulture Supernatants Using High-Resolution Nuclear Magnetic Resonance and Directly Coupled High-Pressure Liquid Chromatography–Nuclear Magnetic Resonance Spectroscopy

article

Characterization of metabolic responses to healthy diets and association with blood pressure: application to the Optimal Macronutrient Intake Trial for Heart Health (OmniHeart), a randomized controlled study

scientific article published on 01 March 2018

Characterization of the biochemical effects of 1-nitronaphthalene in rats using global metabolic profiling by NMR spectroscopy and pattern recognition.

scientific article published in November 2005

Chemical mapping of the colorectal cancer microenvironment via MALDI imaging mass spectrometry (MALDI-MSI) reveals novel cancer-associated field effects

scientific article

Chemical shift calibration of 1H MAS NMR liver tissue spectra exemplified using a study of glycine protection of galactosamine toxicity

scientific article

Chemo-informatic strategy for imaging mass spectrometry-based hyperspectral profiling of lipid signatures in colorectal cancer

scientific article published on 07 January 2014

Chemometric Models for Toxicity Classification Based on NMR Spectra of Biofluids

article

Chemometric analysis of biofluids following toxicant induced hepatotoxicity: a metabonomic approach to distinguish the effects of 1-naphthylisothiocyanate from its products

scientific article published in August 2005

Chiral Metabonomics: 1H NMR-Based Enantiospecific Differentiation of Metabolites in Human Urine via Direct Cosolvation with β-Cyclodextrin

article

Chirality

article

Choline containing metabolites during cell transfection: an insight into magnetic resonance spectroscopy detectable changes

scientific article published in December 2001

Classification of toxin-induced changes in 1H NMR spectra of urine using an artificial neural network

scientific article published in March 1995

Cluster analysis statistical spectroscopy using nuclear magnetic resonance generated metabolic data sets from perturbed biological systems

scientific article

Colonization-induced host-gut microbial metabolic interaction

scientific article

Combined HPLC, NMR Spectroscopy, and Ion-Trap Mass Spectrometry with Application to the Detection and Characterization of Xenobiotic and Endogenous Metabolites in Human Urine

article

Combined proteomic and metabonomic studies in three genetic forms of the renal Fanconi syndrome

scientific article

Comparative biochemical effects of low doses of mercury II chloride in the F344 rat and the multimammate mouse (Mastomys natalensis)

scientific article published on 01 May 1996

Comparative distributions of zinc, cadmium and mercury in the tissues of experimental mice

scientific article published on 01 January 1984

Comparative metabonomics of differential hydrazine toxicity in the rat and mouse

scientific article

Comparative studies on the nephrotoxicity of 2-bromoethanamine hydrobromide in the Fischer 344 rat and the multimammate desert mouse (Mastomys natalensis).

scientific article published on January 1995

Comparison of Maximum Quantum Filtered NMR Spectroscopy (MAXY NMR) and Other Two-Dimensional NMR Approaches for Resonance Assignment of Peptides

Comparison of in vivo 1H MRS of human brain tumours with 1H HR-MAS spectroscopy of intact biopsy samples in vitro

scientific article published in May 1999

Compartmentation of metabolism probed by [2-13C]alanine: improved 13C NMR sensitivity using a CryoProbe detects evidence of a glial metabolon

scientific article published in January 2003

Conception, Implementation and Operation of Large-Scale Metabolic Phenotyping Centres: Phenome Centres

Contemporary issues in toxicology the role of metabonomics in toxicology and its evaluation by the COMET project

scientific article published in March 2003

Contributors

Coordinated multitissue transcriptional and plasma metabonomic profiles following acute caloric restriction in mice.

scientific article

Correction to 2-Furoylglycine as a Candidate Biomarker of Coffee Consumption

scientific article published on 11 November 2016

Coupling of HPLC with 19F- and 1H-NMR spectroscopy to investigate the human urinary excretion of flurbiprofen metabolites

scientific article published on 01 October 1993

Cryogenic Probe13C NMR Spectroscopy of Urine for Metabonomic Studies

article

Curve-fitting method for direct quantitation of compounds in complex biological mixtures using 1H NMR: application in metabonomic toxicology studies

scientific article published in July 2005

Data-Driven Approach for Metabolite Relationship Recovery in Biological 1H NMR Data Sets Using Iterative Statistical Total Correlation Spectroscopy ⬇️

scientific article published on February 16, 2011

Deep learning and 3D-DESI imaging reveal the hidden metabolic heterogeneity of cancer

scientific article

Degradation of 4-fluorobiphenyl in soil investigated by 19F NMR spectroscopy and 10C radiolabelling analysis

scientific article published on 01 February 1999

Detection of Urinary Drug Metabolite (Xenometabolome) Signatures in Molecular Epidemiology Studies via Statistical Total Correlation (NMR) Spectroscopy

article published in 2008

Detection of mono- and di-hexoses as metabolites of 4-bromoaniline using HPLC-TOF-MS/MS.

scientific article published in August 2003

Detection of urinary drug metabolite (xenometabolome) signatures in molecular epidemiology studies via statistical total correlation (NMR) spectroscopy.

scientific article

Detection ofin vivo biomarkers of phospholipidosis using NMR-based metabonomic approaches

article

Determination of the relative NH proton lifetimes of the peptide analogue viomycin in aqueous solution by NMR-based diffusion measurement

scientific article published on January 1, 1999

Deuterium NMR spectroscopy of biofluids for the identification of drug metabolites: Application to N,N-dimethylformamide

scientific article published on 01 August 1993

Development and Application of Ultra-Performance Liquid Chromatography-TOF MS for Precision Large Scale Urinary Metabolic Phenotyping.

scientific article published on August 2016

Development and Validation of a High-Throughput Ultrahigh-Performance Liquid Chromatography-Mass Spectrometry Approach for Screening of Oxylipins and Their Precursors

scientific article published on 26 October 2015

Development and validation of a high performance liquid chromatography-tandem mass spectrometry method for the absolute analysis of 17 α D-amino acids in cooked meals

scientific article published on 04 October 2019

Development of a Pipeline for Exploratory Metabolic Profiling of Infant Urine

scientific article published in August 2016

Development of a Rapid Microbore Metabolic Profiling Ultraperformance Liquid Chromatography-Mass Spectrometry Approach for High-Throughput Phenotyping Studies

scientific article published on 9 May 2016

Development of a model for classification of toxin-induced lesions using1H NMR spectroscopy of urine combined with pattern recognition

article

Development of a simple liquid chromatographic method for the separation of mixtures of positional isomers and anomers of synthetic 2-, 3- and 4-fluorobenzoic acid glucuronides formed via acyl migration reactions

article

Development of nanoelectrospray high resolution isotope dilution mass spectrometry for targeted quantitative analysis of urinary metabolites: application to population profiling and clinical studies

article

Dietary Modulation of Gut Microbiota Contributes to Alleviation of Both Genetic and Simple Obesity in Children

scientific article published on 10 July 2015

Dietary and social modulation of gut microbiota in the elderly ⬇️

scientific article published on 04 September 2012

Dietary and urinary metabonomic factors possibly accounting for higher blood pressure of black compared with white Americans: results of International Collaborative Study on macro-/micronutrients and blood pressure

scientific article published on 07 October 2013

Dietary fibre to reduce colon cancer risk in Alaska Native people: the Alaska FIRST randomised clinical trial protocol

scientific article published in 2021

Dietary minerals in the gastrointestinal tract: hydroxypolymerisation of aluminium is regulated by luminal mucins

scientific article published on 01 June 1999

Dietary modulation of gut functional ecology studied by fecal metabonomics

scientific article

Differences in Fecal Gut Microbiota, Short-Chain Fatty Acids and Bile Acids Link Colorectal Cancer Risk to Dietary Changes Associated with Urbanization Among Zimbabweans

scientific article published on 22 April 2019

Different levels of polybrominated diphenyl ethers (PBDEs) and chlorinated compounds in breast milk from two U.K. Regions

scientific article

Diffusion and Relaxation Edited Proton NMR Spectroscopy of Plasma Reveals a High-Fidelity Supramolecular Biomarker Signature of SARS-CoV-2 Infection

scientific article published in 2021

Direct coupling of chromatographic separations to NMR spectroscopy

article

Direct observation of resolved intracellular and extracellular water signals in intact human red blood cells using 1H MAS NMR spectroscopy.

scientific article published on August 1997

Direct quantitative trait locus mapping of mammalian metabolic phenotypes in diabetic and normoglycemic rat models

scientific article published on 15 April 2007

Directly Coupled 800 MHz HPLC−NMR Spectroscopy of Urine and Its Application to the Identification of the Major Phase II Metabolites of Tolfenamic Acid

scientific article published in 1997

Directly Coupled Chiral HPLC−NMR and HPLC−CD Spectroscopy as Complementary Methods for Structural and Enantiomeric Isomer Identification: Application to Atracurium Besylate

scientific article published in 1999

Directly coupled CZE-NMR and CEC-NMR spectroscopy for metabolite analysis: paracetamol metabolites in human urine

article

Directly coupled HPLC-NMR and HPLC-MS approaches for the rapid characterisation of drug metabolites in urine: application to the human metabolism of naproxen

scientific article

Directly coupled HPLC-NMR and HPLC-NMR-MS in pharmaceutical research and development

scientific article

Directly coupled high-performance liquid chromatography and nuclear magnetic resonance spectroscopic with chemometric studies on metabolic variation in Sprague--Dawley rats

scientific article published in April 2001

Directly-coupled HPLC-NMR spectroscopic studies of metabolism and futile deacetylation of phenacetin in the rat

article

Discovery and validation of urinary metabotypes for the diagnosis of hepatocellular carcinoma in West Africans.

scientific article published on 25 August 2014

Distinction between normal and renal cell carcinoma kidney cortical biopsy samples using pattern recognition of (1)H magic angle spinning (MAS) NMR spectra

scholarly article by A. Rosemary Tate et al published April 2000 in NMR in Biomedicine

Dynamic biochemical information recovery in spontaneous human seminal fluid reactions via 1H NMR kinetic statistical total correlation spectroscopy

scientific article

Early intervention with Bifidobacterium lactis NCC2818 modulates the host-microbe interface independent of the sustained changes induced by the neonatal environment.

scientific article published on 13 July 2017

Early metabolic adaptation in C57BL/6 mice resistant to high fat diet induced weight gain involves an activation of mitochondrial oxidative pathways

scientific article

Earthworm species of the genus Eisenia can be phenotypically differentiated by metabolic profiling

article

Effect of the histone deacetylase inhibitor trichostatin a on the metabolome of cultured primary hepatocytes

scientific article published in January 2010

Effects of biliary cannulation and buthionine sulphoximine pretreatment on the nephrotoxicity of para-aminophenol in the Fischer 344 rat.

scientific article published in January 1990

Effects of probiotic Lactobacillus paracasei treatment on the host gut tissue metabolic profiles probed via magic-angle-spinning NMR spectroscopy

scientific article

Environmental metabonomics: applying combination biomarker analysis in earthworms at a metal contaminated site.

scientific article published in November 2004

Ethyl glucoside in human urine following dietary exposure: detection by 1H NMR spectroscopy as a result of metabonomic screening of humans

scientific article published on 27 January 2004

Evaluation of full-resolution J-resolved 1H NMR projections of biofluids for metabonomics information retrieval and biomarker identification

scientific article published in March 2010

Evaluation of high resolution magic-angle coil spinning NMR spectroscopy for metabolic profiling of nanoliter tissue biopsies

article

Evaluation of metabolic variation in normal rat strains from a statistical analysis of 1H NMR spectra of urine

article

Evaluation of the orthogonal projection on latent structure model limitations caused by chemical shift variability and improved visualization of biomarker changes in 1H NMR spectroscopic metabonomic studies.

scientific article published in January 2005

Experimental and analytical variation in human urine in 1H NMR spectroscopy-based metabolic phenotyping studies

scientific article published on 8 June 2007

Experimental bariatric surgery in rats generates a cytotoxic chemical environment in the gut contents.

scientific article published on 13 September 2011

Experimental metabonomic model of dietary variation and stress interactions

scientific article

Exploration of the direct metabolic effects of mercury II chloride on the kidney of Sprague-Dawley rats using high-resolution magic angle spinning 1H NMR spectroscopy of intact tissue and pattern recognition

scientific article

Extraction, interpretation and validation of information for comparing samples in metabolic LC/MS data sets

scientific article

Fat, fibre and cancer risk in African Americans and rural Africans

scientific article

First example of hepatocyte transplantation to alleviate ornithine transcarbamylase deficiency, monitored by NMR-based metabonomics

scientific article published on December 2009

Future Visions for Clinical Metabolic Phenotyping

Gastro-intestinal availability of aluminium from tea

scientific article published on 01 June 1993

Generation of Ultrahigh Peak Capacity LC Separations via Elevated Temperatures and High Linear Mobile-Phase Velocities

article

Genetic algorithms for simultaneous variable and sample selection in metabonomics

scientific article published on 14 November 2008

Genetic determinants of metabolism in health and disease: from biochemical genetics to genome-wide associations.

scientific article

Geometric trajectory analysis of metabolic responses to toxicity can define treatment specific profiles

scientific article

Global Systems Biology Through Integration of “Omics” Results

Global metabolic phenotyping in an experimental laparotomy model of surgical trauma

article

Global metabolic profiling of animal and human tissues via UPLC-MS.

scientific article published on 6 December 2012

Global metabolic profiling procedures for urine using UPLC–MS

article

Global metabolic responses of NMRI mice to an experimental Plasmodium berghei infection

scientific article published on 23 July 2008

Global metabolic responses of mice to Trypanosoma brucei brucei infection

scientific article

Global systems biology and personalized healthcare solutions

scientific article published on 01 April 2006

Global systems biology, personalized medicine and molecular epidemiology

scientific article

Global urinary metabolic profiling procedures using gas chromatography–mass spectrometry

Gut Microbiota Composition and Activity in Relation to Host Metabolic Phenotype and Disease Risk ⬇️

scientific article published on November 7, 2012

Gut Microbiota Modulate the Metabolism of Brown Adipose Tissue in Mice

scientific article published on 21 November 2011

Gut microbiome interactions with drug metabolism, efficacy, and toxicity

scientific article

Gut microbiome modulates the toxicity of hydrazine: a metabonomic study

article

Gut microbiome-host interactions in health and disease ⬇️

scientific article published on March 4, 2011

Gut microbiomes of Malawian twin pairs discordant for kwashiorkor

scientific article published on 30 January 2013

Gut microbiota modulation of chemotherapy efficacy and toxicity.

scientific article

Gut microbiota: a potential new territory for drug targeting

scientific article published on 01 February 2008

Gut microorganisms, mammalian metabolism and personalized health care

scientific article

HILIC-UPLC-MS for Exploratory Urinary Metabolic Profiling in Toxicological Studies

article

HPLC/1H NMR spectroscopic studies of the reactive alpha-1-O-acyl isomer formed during acyl migration of S-naproxen beta-1-O-acyl glucuronide

scientific article

Hepatotoxin-induced hypercreatinaemia and hypercreatinuria: their relationship to one another, to liver damage and to weakened nutritional status

scientific article published in October 2003

Hepatotoxin-induced hypertaurinuria: a proton NMR study

article

Hepatotoxin-induced hypertyrosinemia and its toxicological significance

Heteronuclear 19F-1H statistical total correlation spectroscopy as a tool in drug metabolism: study of flucloxacillin biotransformation

scientific article published on 23 January 2008

Heteronuclear 1H-31P statistical total correlation NMR spectroscopy of intact liver for metabolic biomarker assignment: application to galactosamine-induced hepatotoxicity

scientific article published in November 2007

High resolution "ultra performance" liquid chromatography coupled to oa-TOF mass spectrometry as a tool for differential metabolic pathway profiling in functional genomic studies

scientific article

High resolution 1H NMR spectroscopic studies on dynamic biochemical processes in incubated human seminal fluid samples

article

High resolution NMR spectroscopic studies on the metabolism and futile deacetylation of 4-hydroxyacetanilide (paracetamol) in the rat

article

High resolution proton magnetic resonance spectroscopy of biological fluids

High resolution proton magnetic resonance spectroscopy of cyst fluids from patients with polycystic kidney disease

scientific article published in April 1992

High-Field Deuterium Nuclear Magnetic Resonance Spectroscopic Monitoring of the Pharmacokinetics of Selectively Deuterated Benzoic Acid in Man

scientific article published on 01 September 1994

High-Speed Quantitative UPLC-MS Analysis of Multiple Amines in Human Plasma and Serum via Precolumn Derivatization with 6-Aminoquinolyl-N-hydroxysuccinimidyl Carbamate: Application to Acetaminophen-Induced Liver Failure.

scientific article published on 7 February 2017

High-Throughput Microbore UPLC–MS Metabolic Phenotyping of Urine for Large-Scale Epidemiology Studies

article

High-performance liquid chromatography and inductively coupled plasma mass spectrometry (HPLC-ICP-MS) for the analysis of xenobiotic metabolites in rat urine: application to the metabolites of 4-bromoaniline

scientific article published on 01 February 2000

High-performance liquid chromatography linked to inductively coupled plasma mass spectrometry and orthogonal acceleration time-of-flight mass spectrometry for the simultaneous detection and identification of metabolites of 2-bromo-4-trifluoromethyl

scientific article published in April 2001

High-performance liquid chromatography/inductively coupled plasma mass spectrometry with iodine-specific detection for profiling the metabolites produced in the earthworm Eisenia veneta by exposure to 2-fluoro-4-iodoaniline

scientific article published in January 2003

High-performance liquid chromatography/mass spectrometric and proton nuclear magnetic resonance spectroscopic studies of the transacylation and hydrolysis of the acyl glucuronides of a series of phenylacetic acids in buffer and human plasma

scientific article published on October 2010

High-resolution (1)H NMR and magic angle spinning NMR spectroscopic investigation of the biochemical effects of 2-bromoethanamine in intact renal and hepatic tissue

scientific article published in May 2001

High-resolution diffusion and relaxation-edited magic angle spinning 1H NMR spectroscopy of intact liver tissue

scientific article published in November 2003

High-resolution magic angle spinning (1)H NMR spectroscopy of intact liver and kidney: optimization of sample preparation procedures and biochemical stability of tissue during spectral acquisition

scientific article published on 01 June 2000

High-resolution magic angle spinning 1H NMR spectroscopic studies on intact rat renal cortex and medulla

scientific article published on 01 June 1999

High-resolution magic angle spinning NMR spectroscopy: Application to biomedical studies

article

High-resolution magic-angle-spinning 1H NMR spectroscopy reveals different responses in choline-containing metabolites upon gene therapy-induced programmed cell death in rat brain glioma.

scientific article

High-resolution magic-angle-spinning NMR spectroscopy for metabolic profiling of intact tissues

scientific article published on 13 May 2010

High-throughput 1H NMR-based metabolic analysis of human serum and urine for large-scale epidemiological studies: validation study

scientific article

Hippurate: the natural history of a mammalian-microbial cometabolite.

scientific article

Host-Gut Microbiota Metabolic Interactions ⬇️

scientific article (publication date: 8 June 2012)

How has healthcare research performance been assessed?: a systematic review

scientific article published in June 2011

Human metabolic phenotype diversity and its association with diet and blood pressure.

scientific article

Human metabolic phenotypes link directly to specific dietary preferences in healthy individuals

scientific article

Human metabolic profiles are stably controlled by genetic and environmental variation

scientific article

Hyperspectral visualization of mass spectrometry imaging data.

scientific article

Hyphenated methods

Identification of metabolites in human hepatic bile using 800 MHz 1H NMR spectroscopy, HPLC-NMR/MS and UPLC-MS.

scientific article published on 15 December 2008

Identification of novel hydrazine metabolites by 15N-NMR

scientific article published on 01 May 1991

Identification of the Positional Isomers of 2-Fluorobenzoic acid 1-O-Acyl Glucuronide by Directly Coupled HPLC-NMR

scientific article published in 1995

Identification of the urinary metabolites of 4-bromoaniline and 4-bromo-[carbonyl-13C]-acetanilide in rat.

scientific article published in April 2002

Identifying unknown metabolites using NMR-based metabolic profiling techniques

scientific article published on 17 July 2020

Impact of a care coordination and support strategic partnership on clinical outcomes

scientific article published in March 2008

Impact of analytical bias in metabonomic studies of human blood serum and plasma

scientific article published in July 2006

Impact of the gut microbiota on inflammation, obesity, and metabolic disease

scientific article

Implementation of molecular phenotyping approaches in the personalized surgical patient journey

scientific article

Improved Spatial Resolution of Metabolites in Tissue Biopsies Using High-Resolution Magic-Angle-Spinning Slice Localization NMR Spectroscopy

scientific article published on 20 August 2020

Improved analysis of multivariate data by variable stability scaling: application to NMR-based metabolic profiling

article

Improvement in the characterization of minor drug metabolites from HPLC-NMR studies through the use of quantified maximum entropy processing of NMR spectra

scientific article published on 01 March 1994

Impurity profiling in bulk pharmaceutical batches using 19F NMR spectroscopy and distinction between monomeric and dimeric impurities by NMR-based diffusion measurements

scientific article published on 01 March 1999

In Vivo Endoscopic Tissue Identification by Rapid Evaporative Ionization Mass Spectrometry (REIMS)

scientific article published on 06 August 2015

In-vitro identification of distinctive metabolic signatures of intact varicose vein tissue via magic angle spinning nuclear magnetic resonance spectroscopy

scientific article published on 20 July 2012

Incomplete Systemic Recovery and Metabolic Phenoreversion in Post-Acute-Phase Nonhospitalized COVID-19 Patients: Implications for Assessment of Post-Acute COVID-19 Syndrome

Induction of 5-oxoprolinuria in the rat following chronic feeding with N -acetyl 4-aminophenol (paracetamol)

scientific article published on 01 September 1993

Integrated Analytical and Statistical Two-Dimensional Spectroscopy Strategy for Metabolite Identification: Application to Dietary Biomarkers. ⬇️

scientific article published on 27 February 2017

Integrated HPLC-MS and (1)H-NMR spectroscopic studies on acyl migration reaction kinetics of model drug ester glucuronides.

scientific article published in January 2010

Integrated application of transcriptomics and metabonomics yields new insight into the toxicity due to paracetamol in the mouse

scientific article published in April 2004

Integrated cytokine and metabolic analysis of pathological responses to parasite exposure in rodents

scientific article

Integrated histopathological and urinary metabonomic investigation of the pathogenesis of microcystin-LR toxicosis

scientific article published on 2 May 2012

Integrated metabonomic analysis of bromobenzene-induced hepatotoxicity: novel induction of 5-oxoprolinosis

article

Integrated metabonomic analysis of the multiorgan effects of hydrazine toxicity in the rat.

scientific article

Integrated metabonomic-proteomic analysis of an insect-bacterial symbiotic system

scientific article published in March 2010

Integrative Modelling of Quantitative Plasma Lipoprotein, Metabolic and Amino Acid Data Reveals a Multi-organ Pathological Signature of SARS-CoV-2 Infection

scientific article published on 17 August 2020

Integrative Top-Down System Metabolic Modeling in Experimental Disease States via Data-Driven Bayesian Methods

Integrative top-down system metabolic modeling in experimental disease states via data-driven Bayesian methods

scientific article

Intestinal ischemia/reperfusion injury: defining the role of the gut microbiome

scientific article published on April 2009

Intra- and Interlaboratory Reproducibility of Ultra Performance Liquid Chromatography–Time-of-Flight Mass Spectrometry for Urinary Metabolic Profiling

article

Intra- and inter-omic fusion of metabolic profiling data in a systems biology framework

article by Selena E. Richards et al published November 2010 in Chemometrics and Intelligent Laboratory Systems

Intraoperative tissue identification using rapid evaporative ionization mass spectrometry

scientific article

Investigation of Basic Mobile Phases With Positive Esi Lc–Ms For Metabonomics Studies ⬇️

scientific article published on 01 December 2012

Investigation of the feasibility of directly-coupled HPLC-NMR with 2H detection with application to the metabolism of N-dimethylformamide-d7

scientific article published on 01 September 1997

Investigation of the metabolic fate of 2-, 3- and 4-bromobenzoic acids in bile-duct-cannulated rats by inductively coupled plasma mass spectrometry and high-performance liquid chromatography/inductively coupled plasma mass spectrometry/electrospray m

scientific article published on 01 January 2005

Investigations into biochemical changes due to diurnal variation and estrus cycle in female rats using high-resolution (1)H NMR spectroscopy of urine and pattern recognition

scientific article published in August 2001

Ion mobility spectrometry combined with ultra performance liquid chromatography/mass spectrometry for metabolic phenotyping of urine: Effects of column length, gradient duration and ion mobility spectrometry on metabolite detection.

scientific article published on 19 June 2017

Iron status influences non-alcoholic fatty liver disease in obesity through the gut microbiome

scientific article published on 7 May 2021

Isotopic enrichment enhancement in metabonomic analysis of UPLC–MS data sets

article

J-Resolved 1H NMR 1D-Projections for Large-Scale Metabolic Phenotyping Studies: Application to Blood Plasma Analysis.

scientific article published on 22 September 2017

K-OPLS package: kernel-based orthogonal projections to latent structures for prediction and interpretation in feature space

scientific article

Kernel-based orthogonal projections to latent structures (K-OPLS)

scholarly article by Mattias Rantalainen et al published 2007 in Journal of Chemometrics

Kinetic and J-resolved statistical total correlation NMR spectroscopy approaches to structural information recovery in complex reacting mixtures: application to acyl glucuronide intramolecular transacylation reactions

scientific article published on 10 May 2008

Kinetic studies on the intramolecular acyl migration of beta-1-O-acyl glucuronides: application to the glucuronides of (R)- and (S)-ketoprofen, (R)- and (S)-hydroxy-ketoprofen metabolites, and tolmetin by 1H-NMR spectroscopy

scientific article published in July 2005

Large-scale human metabolic phenotyping and molecular epidemiological studies via 1H NMR spectroscopy of urine: investigation of borate preservation

scientific article published on June 2009

Liquid chromatography coupled with high-field proton NMR for profiling human urine for endogenous compounds and drug metabolites

scientific article published on 01 August 1992

Liquid chromatography-mass spectrometry methods for urinary biomarker detection in metabonomic studies with application to nutritional studies

scientific article

Longitudinal analysis of serum oxylipin profile as a novel descriptor of the inflammatory response to surgery.

scientific article published on 26 April 2017

Longitudinal metabolic and gut bacterial profiling of pregnant women with previous bariatric surgery

scientific article published on 21 January 2020

Longitudinal pharmacometabonomics for predicting patient responses to therapy: drug metabolism, toxicity and efficacy

scientific article published on 17 January 2012

Low Volume in Vitro Diagnostic Proton NMR Spectroscopy of Human Blood Plasma for Lipoprotein and Metabolite Analysis: Application to SARS-CoV-2 Biomarkers

MONITORING METABOLIC DISEASE BY PROTON NMR OF URINE

scientific article published in The Lancet

MWASTools: an R/Bioconductor package for metabolome-wide association studies.

scientific article published on 26 July 2017

Magic angle spinning NMR and 1H-31P heteronuclear statistical total correlation spectroscopy of intact human gut biopsies

scientific article

Manuscript Strategy for improved characterisation of human metabolic phenotypes using a COmbined Multiblock Principal components Analysis with Statistical Spectroscopy (COMPASS)

scientific article published on 21 July 2020

Mass spectrometrically detected directly coupled high performance liquid chromatography/nuclear magnetic resonance spectroscopy/mass spectrometry for the identification of xenobiotic metabolites in maize plants

article

Mechanistic aspects and novel biomarkers of responder and non-responder phenotypes in galactosamine-induced hepatitis

scientific article published in November 2009

Melamine-induced renal toxicity is mediated by the gut microbiota

scientific article

MetaboNetworks, an interactive Matlab-based toolbox for creating, customizing and exploring sub-networks from KEGG

scientific article (publication date: 30 October 2013)

MetaboSignal: a network-based approach for topological analysis of metabotype regulation via metabolic and signaling pathways. ⬇️

scientific article published on 22 December 2016

Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids

scientific article published on 18 June 2020

Metabolic Modeling in Health and Disease

scientific article published on 4 March 2022

Metabolic Phenotype Modulation by Caloric Restriction in a Lifelong Dog Study

scientific article published on 25 June 2013

Metabolic Phenotypes of Carotid Atherosclerotic Plaques Relate to Stroke Risk: An Exploratory Study.

scientific article

Metabolic Phenotyping Using UPLC–MS and Rapid Microbore UPLC–IM–MS: Determination of the Effect of Different Dietary Regimes on the Urinary Metabolome of the Rat

scientific article published in 2020

Metabolic Phenotyping in Personalized and Public Healthcare. List of Contributors

section of a book

Metabolic Phenotyping in Personalized and Public Healthcare. Preface

preface of a book

Metabolic Phenotyping: History, Status, and Prospects

Metabolic assessment of human liver transplants from biopsy samples at the donor and recipient stages using high-resolution magic angle spinning 1H NMR spectroscopy

scientific article published in September 2005

Metabolic phenotype-microRNA data fusion analysis of the systemic consequences of Roux-en-Y gastric bypass surgery

scientific article

Metabolic phenotyping and systems biology approaches to understanding metabolic syndrome and fatty liver disease

scientific article

Metabolic phenotyping for discovery of urinary biomarkers of diet, xenobiotics and blood pressure in the INTERMAP Study: an overview.

scientific article

Metabolic phenotyping for monitoring surgical patients ⬇️

scientific article published on May 17, 2011

Metabolic phenotyping in clinical and surgical environments

scientific article

Metabolic phenotyping in health and disease

scientific article

Metabolic phenotyping of atherosclerotic plaques reveals latent associations between free cholesterol and ceramide metabolism in atherogenesis

scientific article published on 23 February 2015

Metabolic phenotyping of nude and normal (Alpk:ApfCD, C57BL10J) mice

scientific article published in February 2006

Metabolic profiling and population screening of analgesic usage in nuclear magnetic resonance spectroscopy-based large-scale epidemiologic studies

scientific article published on July 2009

Metabolic profiling and the metabolome-wide association study: significance level for biomarker identification

scientific article

Metabolic profiling of CHO-AβPP695 cells revealed mitochondrial dysfunction prior to amyloid-β pathology and potential therapeutic effects of both PPARγ and PPARα Agonisms for Alzheimer's disease.

scientific article

Metabolic profiling of CSF: evidence that early intervention may impact on disease progression and outcome in schizophrenia

scientific article

Metabolic profiling of chronic cadmium exposure in the rat.

scientific article

Metabolic profiling of genetic disorders: a multitissue (1)H nuclear magnetic resonance spectroscopic and pattern recognition study into dystrophic tissue

scientific article published in June 2001

Metabolic profiling of human colorectal cancer using high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) spectroscopy and gas chromatography mass spectrometry (GC/MS).

scientific article

Metabolic profiling of rodent biological fluids via 1H NMR spectroscopy using a 1 mm microlitre probe

article

Metabolic profiling of the effects of D-galactosamine in liver spheroids using (1)H NMR and MAS-NMR spectroscopy

scientific article published in November 2002

Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice

scholarly article

Metabolic profiling strategy for discovery of nutritional biomarkers: proline betaine as a marker of citrus consumption

scientific article

Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts

scientific article

Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota.

scientific article published on 20 April 2018

Metabolic retroconversion of trimethylamineN-oxide and the gut microbiota

Metabolic shifts due to long-term caloric restriction revealed in nonhuman primates

scientific article

Metabolic surgery profoundly influences gut microbial-host metabolic cross-talk.

scientific article published on 14 May 2011

Metabolic trajectory characterisation of xenobiotic-induced hepatotoxic lesions using statistical batch processing of NMR data

scientific article

Metabolism of 2-fluoro-4-iodoaniline in earthworm Eisenia veneta using (19)F-NMR spectroscopy, HPLC-MS, and HPLC-ICPMS ((127)I).

scientific article published in December 2007

Metabolism of 3-chloro-4-fluoroaniline in rat using [14C]-radiolabelling, 19F-NMR spectroscopy, HPLC-MS/MS, HPLC-ICPMS and HPLC-NMR.

scientific article published in January 2006

Metabolism of 4-fluoroaniline and 4-fluorobiphenyl in the earthworm Eisenia veneta characterized by high-resolution NMR spectroscopy with directly coupled HPLC-NMR and HPLC-MS.

scientific article published in June 2002

Metabolism of [14C]-5-chloro-1,3-benzodioxol-4-amine in male Wistar-derived rats following intraperitoneal administration

scientific article published on 01 January 2007

Metabolite changes in BT4C rat gliomas undergoing ganciclovir-thymidine kinase gene therapy-induced programmed cell death as studied by 1H NMR spectroscopy in vivo, ex vivo, and in vitro.

scientific article

Metabolome, transcriptome, and bioinformatic cis-element analyses point to HNF-4 as a central regulator of gene expression during enterocyte differentiation

scientific article published on 25 July 2006

Metabolome-wide association study identifies multiple biomarkers that discriminate north and south Chinese populations at differing risks of cardiovascular disease: INTERMAP study

scientific article

Metabolomic Strategy for the Classification and Quality Control of Phytomedicine: A Case Study of Chamomile Flower (Matricaria recutitaL.)

scientific article published on 01 March 2004

Metabolomic analysis of the consequences of cadmium exposure in Silene cucubalus cell cultures via 1H NMR spectroscopy and chemometrics

scientific article published in March 2003

Metabonomic Investigations of Aging and Caloric Restriction in a Life-Long Dog Study

scientific article published on 06 April 2007

Metabonomic Studies on the Physiological Effects of Acute and Chronic Psychological Stress in Sprague−Dawley Rats

article

Metabonomic and microbiological analysis of the dynamic effect of vancomycin-induced gut microbiota modification in the mouse.

scientific article published on 13 August 2008

Metabonomic assessment of toxicity of 4-fluoroaniline, 3,5-difluoroaniline and 2-fluoro-4-methylaniline to the earthworm Eisenia veneta (Rosa): identification of new endogenous biomarkers

scientific article published in September 2002

Metabonomic characterization of genetic variations in toxicological and metabolic responses using probabilistic neural networks

scientific article published on February 2001

Metabonomic deconvolution of embedded toxicity: application to thioacetamide hepato- and nephrotoxicity

scientific article published in April 2005

Metabonomic investigations in mice infected with Schistosoma mansoni: an approach for biomarker identification

scholarly article

Metabonomic investigations into hydrazine toxicity in the rat.

scientific article published in August 2001

Metabonomic investigations into the global biochemical sequelae of exposure to the pancreatic toxin 1-cyano-2-hydroxy-3-butene in the rat.

scientific article published in December 2009

Metabonomics and Metabolomics Techniques and Their Applications in Mammalian Systems

Metabonomics and its role in drug development and disease diagnosis

scientific article published on March 2004

Metabonomics in diabetes research

scientific article published on July 2007

Metabonomics in pharmaceutical R&D.

scientific article published on March 2007

Metabonomics in ulcerative colitis: diagnostics, biomarker identification, and insight into the pathophysiology

scientific article published in February 2010

Metabonomics techniques and applications to pharmaceutical research & development

scientific article

Metabonomics technologies and their applications in physiological monitoring, drug safety assessment and disease diagnosis

scientific article published on January 2004

Metabonomics: a platform for studying drug toxicity and gene function

scientific article

Metabonomics: systems biology in pharmaceutical research and development

scientific article published in June 2004

Metabotyping of Long-Lived Mice using 1H NMR Spectroscopy ⬇️

scientific article published on February 27, 2012

Microbial-Host Co-metabolites Are Prodromal Markers Predicting Phenotypic Heterogeneity in Behavior, Obesity, and Impaired Glucose Tolerance

scientific article

Microbial-mammalian cometabolites dominate the age-associated urinary metabolic phenotype in Taiwanese and American populations

scientific article published on 24 June 2013

Microbiome inhibition of IRAK-4 by trimethylamine mediates metabolic and immune benefits in high-fat-diet-induced insulin resistance

Microbiome-host systems interactions: protective effects of propionate upon the blood-brain barrier

scientific article published on 21 March 2018

Microbiome–host systems interactions: Protective effects of propionate upon the blood–brain barrier

Mistargeting of peroxisomal EHHADH and inherited renal Fanconi's syndrome

scientific article

Modeling Longitudinal Metabonomics and Microbiota Interactions in C57BL/6 Mice Fed a High Fat Diet

scientific article published on 10 July 2016

Modeling People and Populations

Modeling the effects of toxins in metabolic networks

scientific article published in March 2007

Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women

scientific article published on 25 June 2018

Multi-Component Metabolic Classification of Commercial Feverfew Preparations via High-Field 1H-NMR Spectroscopy and Chemometrics

scientific article published on 01 August 2002

Multivariate Data Analysis Methods for NMR-based Metabolic Phenotyping in Pharmaceutical and Clinical Research

scientific article

Multivariate metabotyping of plasma predicts survival in patients with decompensated cirrhosis

scientific article published on 18 January 2016

NMR Spectroscopic Windows on the Systemic Effects of SARS-CoV-2 Infection on Plasma Lipoproteins and Metabolites in Relation to Circulating Cytokines

NMR Spectroscopic and Theoretical Chemistry Studies on the Internal Acyl Migration Reactions of the 1-O-Acyl-β-d-glucopyranuronate Conjugates of 2-, 3-, and 4-(Trifluoromethyl)benzoic Acids

article

NMR Spectroscopy of Biofluids

article

NMR and HPLC-NMR spectroscopic studies of futile deacetylation in paracetamol metabolites in rat and man

article

NMR and QSAR studies on the transacylation reactivity of model 1beta-O-acyl glucuronides. I: design, synthesis and degradation rate measurement

scientific article

NMR and pattern recognition studies on liver extracts and intact livers from rats treated with alpha-naphthylisothiocyanate

scientific article

NMR spectroscopic studies of the transacylation reactivity of ibuprofen 1-beta-O-acyl glucuronide

scientific article published on 17 February 2006

NMR spectroscopic studies on the in vitro acyl glucuronide migration kinetics of Ibuprofen ((+/-)-(R,S)-2-(4-isobutylphenyl) propanoic acid), its metabolites, and analogues

scientific article published on 18 October 2007

NMR spectroscopic studies on the metabolism and futile deacetylation of phenacetin in the rat

scientific article published on 01 November 1997

NMR spectroscopic-based metabonomic studies of urinary metabolite variation in acclimatizing germ-free rats

scientific article published in November 2003

NMR-based metabolic profiling and metabonomic approaches to problems in molecular toxicology

scientific article published on 03 January 2008

NMR-based metabolic profiling identifies biomarkers of liver regeneration following partial hepatectomy in the rat.

scientific article published in January 2010

NMR-based metabonomic approaches for evaluating physiological influences on biofluid composition

scientific article

NMR-based metabonomic studies on the biochemical effects of commonly used drug carrier vehicles in the rat.

scientific article

NMR-based metabonomic studies on the biochemical effects of epicatechin in the rat.

scientific article

NMR-based metabonomic toxicity classification: hierarchical cluster analysis and k-nearest-neighbour approaches

article

NMR-monitored solid-phase extraction of phenolphthalein glucuronide on phenylboronic acid and C18 bonded phases

scientific article published on 01 January 1991

Neonatal environment exerts a sustained influence on the development of the intestinal microbiota and metabolic phenotype

scientific article published on 12 June 2015

Nephrocalcinosis (enamel renal syndrome) caused by autosomal recessive FAM20A mutations ⬇️

scientific article

Network Mapping of Molecular Biomarkers Influencing Radiation Response in Rectal Cancer

scientific article published on 10 February 2019

Network analysis of mass spectrometry imaging data from colorectal cancer identifies key metabolites common to metastatic development

article

Neurogenesis and prolongevity signaling in young germ-free mice transplanted with the gut microbiota of old mice

scientific article published on 01 November 2019

Non-linear modeling of 1H NMR metabonomic data using kernel-based orthogonal projections to latent structures optimized by simulated annealing

scientific article

Novel application of reversed-phase UPLC-oaTOF-MS for lipid analysis in complex biological mixtures: a new tool for lipidomics.

scientific article

Nuclear Magnetic Resonance Spectroscopic and Principal Components Analysis Investigations into Biochemical Effects of Three Model Hepatotoxins

article

Nuclear Magnetic Resonance and High-Performance Liquid Chromatography-Nuclear Magnetic Resonance Studies on the Toxicity and Metabolism of Ifosfamide

article

Nutriome-metabolome relationships provide insights into dietary intake and metabolism

scientific article published on 22 June 2020

Nutritional modulation of the metabonome: applications of metabolic phenotyping in translational nutritional research

scientific article published on March 2014

OPLS discriminant analysis: combining the strengths of PLS-DA and SIMCA classification

article

Obesity and Cage Environment Modulate Metabolism in the Zucker Rat: A Multiple Biological Matrix Approach to Characterizing Metabolic Phenomena

scientific article published on 18 April 2019

Objective assessment of dietary patterns by use of metabolic phenotyping: a randomised, controlled, crossover trial

scientific article published on 12 January 2017

Objective set of criteria for optimization of sample preparation procedures for ultra-high throughput untargeted blood plasma lipid profiling by ultra performance liquid chromatography-mass spectrometry

scientific article published on 2 June 2014

Opening up the "Black Box": metabolic phenotyping and metabolome-wide association studies in epidemiology

scientific article published on 08 January 2010

Optimization and Application of Direct Infusion Nanoelectrospray HRMS Method for Large-Scale Urinary Metabolic Phenotyping in Molecular Epidemiology

scientific article

Optimization and evaluation of metabolite extraction protocols for untargeted metabolic profiling of liver samples by UPLC-MS.

scientific article published on September 2010

Optimization of human plasma 1H NMR spectroscopic data processing for high-throughput metabolic phenotyping studies and detection of insulin resistance related to type 2 diabetes

scientific article

Optimized Phenotypic Biomarker Discovery and Confounder Elimination via Covariate-Adjusted Projection to Latent Structures from Metabolic Spectroscopy Data

scientific article published on 19 February 2018

Optimized Preprocessing of Ultra-Performance Liquid Chromatography/Mass Spectrometry Urinary Metabolic Profiles for Improved Information Recovery

article

Optimized Sample Handling Strategy for Metabolic Profiling of Human Feces.

scientific article

Overview of the Nomenclature and Network of Contributors to the Development of Bioreactors for Human Gut Simulation Using Bibliometric Tools: A Fragmented Landscape

scientific article published in 2022

Panorganismal gut microbiome-host metabolic crosstalk

scientific article published in April 2009

Panorganismal metabolic response modeling of an experimental Echinostoma caproni infection in the mouse

scientific article

Paracetamol metabolism, hepatotoxicity, biomarkers and therapeutic interventions: a perspective

scientific article published on 06 March 2018

Pharmaco-metabonomic phenotyping and personalized drug treatment

scientific article

Pharmacometabonomic Characterization of Xenobiotic and Endogenous Metabolic Phenotypes That Account for Inter-individual Variation in Isoniazid-Induced Toxicological Response

article

Pharmacometabonomic Investigation of Dynamic Metabolic Phenotypes Associated with Variability in Response to Galactosamine Hepatotoxicity

article

Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism

scientific article published on 10 August 2009

Pharmacometabonomics and Predictive Metabonomics

Pharmacometabonomics as an effector for personalized medicine.

scientific article published on January 2011

Phenotyping the Patient Journey

Phylometabonomic patterns of adaptation to high fat diet feeding in inbred mice

scientific article

Physiological variation in metabolic phenotyping and functional genomic studies: use of orthogonal signal correction and PLS-DA.

scientific article published in October 2002

Piecewise multivariate modelling of sequential metabolic profiling data

scientific article

Power Analysis and Sample Size Determination in Metabolic Phenotyping

scientific article

Precision High-Throughput Proton NMR Spectroscopy of Human Urine, Serum, and Plasma for Large-Scale Metabolic Phenotyping

article

Prediction and classification of drug toxicity using probabilistic modeling of temporal metabolic data: the consortium on metabonomic toxicology screening approach

scientific article

Prediction of urinary sulphate and glucuronide conjugate excretion for substituted phenols in the rat using quantitative structure-metabolism relationships

scientific article published in December 1995

Preface

Preface

Preparing for Precision Medicine

article

Probing latent biomarker signatures and in vivo pathway activity in experimental disease states via statistical total correlation spectroscopy (STOCSY) of biofluids: application to HgCl2 toxicity

scientific article published in June 2006

Probing molecular dynamics in chromatographic systems using high-resolution 1H magic-angle-spinning NMR spectroscopy: interaction between p-Xylene and C18-bonded silica

scientific article

Probiotic modulation of symbiotic gut microbial-host metabolic interactions in a humanized microbiome mouse model

scientific article

Proton MRS of human prostatic fluid: Correlations between citrate, spermine, andmyo-inositol levels and changes with disease

scientific article published on 01 March 1997

Proton NMR analysis of plasma from renal failure patients: Evaluation of sample preparation and spectral-editing methods

scientific article published on 01 January 1990

Proton NMR monitoring of the onset and recovery of experimental renal damage

article

Proton NMR spectroscopic studies on the metabolism and biochemical effects of hydrazine in vivo

scientific article published on 01 January 1992

Proton NMR spectroscopy of bile for monitoring the excretion of endogenous and xenobiotic metabolites: Application to para-aminophenol

scientific article published on 01 January 1989

Proton NMR studies on the effects of uranyl nitrate on the biochemical composition of rat urine and plasma

scientific article published in January 1990

Proton magnetic resonance spectroscopy of human urine: Excretion of 1-(3'-carboxypropyl)-3,7-dimethylxanthine by man after dosing with oxpentifylline.

scientific article published in January 1987

Proton nuclear magnetic resonance of urine and bile from paracetamol dosed rats

scientific article published on 01 January 1990

Publisher Correction: Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women

scientific article published on 01 October 2018

Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome.

scientific article

Quantitation in gradient high performance liquid chromatography/inductively coupled mass spectrometry investigated using diclofenac and chlorpromazine

scientific article published in January 2002

Quantitative In-Vitro Diagnostic NMR Spectroscopy for Lipoprotein and Metabolite Measurements in Plasma and Serum: Recommendations for Analytical Artefact Minimization with Special Reference to COVID-19/SARS-CoV-2 Samples

scientific article published on 27 August 2020

Quantitative Investigation of Probabilistic Spectral Processing Methods Using Simulated NMR Data

Quantitative Lipoprotein Subclass and Low Molecular Weight Metabolite Analysis in Human Serum and Plasma by 1H NMR Spectroscopy in a Multilaboratory Trial

scientific article published on 27 September 2018

Quantitative UPLC-MS/MS analysis of the gut microbial co-metabolites phenylacetylglutamine, 4-cresyl sulphate and hippurate in human urine: INTERMAP Study

scientific article published on January 2012

Quantitative structure-metabolism relationships for substituted benzoic acids in the rat. Computational chemistry, NMR spectroscopy and pattern recognition studies

scientific article published in November 1992

Quantitative structure-toxicity relationships for halogenated substituted-benzenes to Vibrio fischeri, using atom-based semi-empirical molecular-orbital descriptors.

scientific article published in June 1999

Quantitative studies on the urinary metabolic fate of 2-chloro-4-trifluoromethylaniline in the rat using 19F-NMR spectroscopy and directly coupled HPLCNMR-MS

scientific article published on 01 January 1999

Quantitative urinalysis of the mercapturic acid conjugates of allyl formate using high-resolution NMR spectroscopy

scientific article

Raised transaminase activity of blood plasma from rats with experimentally-induced kidney damage detected by spin-echo 1H-NMR spectroscopy

scientific article published on 01 October 1993

Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics

scientific article

Rapid diagnosis and staging of colorectal cancer via high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) spectroscopy of intact tissue biopsies

scientific article

Recent advances in high-resolution NMR spectroscopic methods in bioanalytical chemistry

Recovery of underwater resonances by magnetization transferred NMR spectroscopy (RECUR-NMR).

scientific article

Recursive segment-wise peak alignment of biological (1)h NMR spectra for improved metabolic biomarker recovery

scientific article published in January 2009

Reduced plasma levels of small HDL particles transporting fibrinolytic proteins in pulmonary arterial hypertension

scientific article published on 26 November 2018

Relation of raw and cooked vegetable consumption to blood pressure: the INTERMAP Study

scientific article

Relationship between vaginal microbial dysbiosis, inflammation, and pregnancy outcomes in cervical cerclage

scientific article published on August 2016

Reply

Response to Comment on “Optimized Preprocessing of Ultra-Performance Liquid Chromatography/Mass Spectrometry Urinary Metabolic Profiles for Improved Information Recovery”

scientific article published in 2011

Reviewers peering from under a pile of 'omics' data.

scientific article published in April 2006

Robust algorithms for automated chemical shift calibration of 1D 1H NMR spectra of blood serum

scientific article published on 15 August 2008

Robust data processing and normalization strategy for MALDI mass spectrometric imaging

scientific article

SPUTNIK: an R package for filtering of spatially related peaks in mass spectrometry imaging data

scientific article published on 01 January 2019

Sample classification based on Bayesian spectral decomposition of metabonomic NMR data sets

scientific article published in July 2004

Scaling and normalization effects in NMR spectroscopic metabonomic data sets

scientific article

Selective Inverse-Detected Long-Range HeteronuclearJ-Resolved NMR Spectroscopy and Its Application to the Measurement of3JCH

Self-modeling curve resolution recovery of temporal metabolite signal modulation in NMR spectroscopic data sets: application to a life-long caloric restriction study in dogs

scientific article

Seminal oligouridinosis: low uridine secretion as a biomarker for infertility in spinal neurotrauma

scientific article published on 2 October 2008

Serum metabolic signatures of coronary and carotid atherosclerosis and subsequent cardiovascular disease

scientific article published on 01 September 2019

Sex-dependent effects on gut microbiota regulate hepatic carcinogenic outcomes

scientific article published on 27 March 2017

Sexual dimorphism in urinary metabolite profiles of Han Wistar rats revealed by nuclear-magnetic-resonance-based metabonomics

scientific article published on 7 February 2005

So what's the deal with metabonomics?

scientific article published on September 2003

Solid phase extraction chromatography and NMR spectroscopy (SPEC-NMR) for the rapid identification of drug metabolites in urine.

scientific article published in January 1988

Spatially resolved metabolic phenotyping of breast cancer by desorption electrospray ionization mass spectrometry

scientific article published on 17 February 2015

Species variation in the fecal metabolome gives insight into differential gastrointestinal function

scientific article

Spectral editing and pattern recognition methods applied to high-resolution magic-angle spinning 1H nuclear magnetic resonance spectroscopy of liver tissues

scientific article published in December 2003

Spectral profiles of cultured neuronal and glial cells derived from HRMAS (1)H NMR spectroscopy

scientific article published in October 2002

Spectroscopic and statistical techniques for information recovery in metabonomics and metabolomics

scientific article published on January 2008

Stability and Robustness of Human Metabolic Phenotypes in Response to Sequential Food Challenges

article

Statistical Correlation and Projection Methods for Improved Information Recovery from Diffusion-Edited NMR Spectra of Biological Samples

article

Statistical HOmogeneous Cluster SpectroscopY (SHOCSY): an optimized statistical approach for clustering of ¹H NMR spectral data to reduce interference and enhance robust biomarkers selection

scientific article

Statistical experimental design and partial least squares regression analysis of biofluid metabonomic NMR and clinical chemistry data for screening of adverse drug effects

article

Statistical heterospectroscopy, an approach to the integrated analysis of NMR and UPLC-MS data sets: application in metabonomic toxicology studies

scientific article

Statistical search space reduction and two-dimensional data display approaches for UPLC-MS in biomarker discovery and pathway analysis

scientific article

Statistical spectroscopic tools for biomarker discovery and systems medicine

scientific article published on 23 May 2013

Statistical total correlation spectroscopy editing of 1H NMR spectra of biofluids: application to drug metabolite profile identification and enhanced information recovery.

scientific article

Statistical total correlation spectroscopy scaling for enhancement of metabolic information recovery in biological NMR spectra

scientific article published on 27 December 2011

Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets

scientific article

Statistically integrated metabonomic-proteomic studies on a human prostate cancer xenograft model in mice

scientific article published on October 2006

Structural shifts of gut microbiota as surrogate endpoints for monitoring host health changes induced by carcinogen exposure

scientific article published on 7 July 2010

Structure-metabolism relationships of substituted anilines: prediction of N-acetylation and N-oxanilic acid formation using computational chemistry

scientific article published in April 2002

Studies of the biochemical toxicology of uranyl nitrate in the rat

scientific article published on 01 January 1994

Studies on the biochemical effects of the aldose reductase inhibitor 2,7-difluorospirofluorene-9,5′-imidazolidine-2′,4′-dione (Al 1576, HOE 843)

scientific article published on 01 July 1992

Studies on the comparative toxicity of S-(1,2-dichlorovinyl)-L-cysteine, S-(1,2-dichlorovinyl)-L-homocysteine and 1,1,2-trichloro-3,3,3-trifluoro-1-propene in the Fischer 344 rat

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Studies on the effects of L(alpha S,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125) on 4-aminophenol-induced nephrotoxicity in the Fischer 344 rat.

scientific article published on January 1993

Studies on the metabolism of fluorinated xenobiotics in the rat using 19F-NMR and 1H-NMR spectroscopy

scientific article published on 01 January 1990

Studies on the relationship between acute testicular damage and urinary and plasma creatine concentration

scientific article published on 01 January 1990

Subset Optimization by Reference Matching (STORM): An Optimized Statistical Approach for Recovery of Metabolic Biomarker Structural Information from 1H NMR Spectra of Biofluids

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Subtle metabolic and liver gene transcriptional changes underlie diet-induced fatty liver susceptibility in insulin-resistant mice

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Summary recommendations for standardization and reporting of metabolic analyses

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Surgical systems biology and personalized longitudinal phenotyping in critical care

Susceptibility of Human Metabolic Phenotypes to Dietary Modulation

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Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and Toll-like receptor 4.

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Symbiotic gut microbes modulate human metabolic phenotypes

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Synthesis of a series of phenylacetic acid 1-β-O-acyl glucosides and comparison of their acyl migration and hydrolysis kinetics with the corresponding acyl glucuronides

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Synthesis, transacylation kinetics and computational chemistry of a set of arylacetic acid 1beta-O-acyl glucuronides.

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System level metabolic effects of a Schistosoma japonicum infection in the Syrian hamster

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Systematic Isolation and Structure Elucidation of Urinary Metabolites Optimized for the Analytical-Scale Molecular Profiling Laboratory

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Systematic evaluation of extraction methods for multiplatform-based metabotyping: application to the Fasciola hepatica metabolome

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Systemic Characterization of an Obese Phenotype in the Zucker Rat Model Defining Metabolic Axes of Energy Metabolism and Host-Microbial Interactions.

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Systemic gut microbial modulation of bile acid metabolism in host tissue compartments

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Systemic multicompartmental effects of the gut microbiome on mouse metabolic phenotypes.

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Systems Genetics of Hepatic Metabolome Reveals Octopamine as a Target for Non-Alcoholic Fatty Liver Disease Treatment

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Systems Toxicology: Integrated Genomic, Proteomic and Metabonomic Analysis of Methapyrilene Induced Hepatotoxicity in the Rat

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Systems biology to battle vascular disease

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Systems biology: Metabonomics

scientific article published in October 2008

Systems parasitology: effects of Fasciola hepatica on the neurochemical profile in the rat brain

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Systems toxicology: modelling biomarkers of glutathione homeostasis and paracetamol metabolism

scientific article published on 16 July 2015

Targeting the human genome-microbiome axis for drug discovery: inspirations from global systems biology and traditional Chinese medicine.

scientific article published on 05 June 2012

Technical and Biological Variation in UPLC−MS-Based Untargeted Metabolic Profiling of Liver Extracts: Application in an Experimental Toxicity Study on Galactosamine

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Temporal metabonomic modeling of l-arginine-induced exocrine pancreatitis

scientific article published on 19 August 2008

The Consortium for Metabonomic Toxicology (COMET): aims, activities and achievements

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The Development of a Metabonomic-Based Drug Safety Testing Paradigm

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The Footprints of Gut Microbial–Mammalian Co-Metabolism

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The Metabolic Window into Systems Biology

The Microbial Metabolite 4-Cresol Improves Glucose Homeostasis and Enhances β-Cell Function

The biochemical profile of rat testicular tissue as measured by magic angle spinning 1H NMR spectroscopy.

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The challenges of modeling mammalian biocomplexity

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The comparative distribution of zinc, cadmium and mercury in selected tissues of the herring gull (Larus argentatus) ⬇️

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The comparison of plasma deproteinization methods for the detection of low-molecular-weight metabolites by (1)H nuclear magnetic resonance spectroscopy

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The effects of kisspeptin on β-cell function, serum metabolites and appetite in humans

scientific article published on 16 August 2018

The emergent role of metabolic phenotyping in dynamic patient stratification

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The evolution of partial least squares models and related chemometric approaches in metabonomics and metabolic phenotyping

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The fox in the box: acoustic deterrent and simulated predator disturbance to reduce problematic bird accumulations

scientific article published in 2022

The gut microbiota as a target for improved surgical outcome and improved patient care

scientific article published on January 2009

The gut microbiota influences skeletal muscle mass and function in mice

scientific article published on 01 July 2019

The human gut microbiome: implications for future health care

scientific article published on August 2008

The identification of novel biomarkers of renal toxicity using automatic data reduction techniques and PCA of proton NMR spectra of urine

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The influence of EDTA and citrate anticoagulant addition to human plasma on information recovery from NMR-based metabolic profiling studies

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The influence of pharmacogenetics on fatty liver disease in the wistar and kyoto rats: a combined transcriptomic and metabonomic study

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The initial pathogenesis of cadmium induced renal toxicity

scholarly article by Julian L. Griffin published in July 2000

The interaction between vaginal microbiota, cervical length, and vaginal progesterone treatment for preterm birth risk

scientific article published on 19 January 2017

The mechanism of galactosamine toxicity revisited; a metabonomic study

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The metabolic fate and effects of 2-Bromophenol in male Sprague-Dawley rats

scientific article published on 22 February 2019

The metabolism and excretion of [14C] 2- and 4-chlorobenzoic acids in the rat

scientific article published on 01 July 2000

The metabolism of 2-trifluormethylaniline and its acetanilide in the rat by 19F NMR monitored enzyme hydrolysis and 1H/19F HPLC-NMR spectroscopy

scientific article published in January 2003

The metabolism of 4-trifluoromethoxyaniline and [13C]-4-trifluoromethoxyacetanilide in the rat: detection and identification of metabolites excreted in the urine by NMR and HPLC-NMR.

scientific article published in June 2002

The metabolite profiles of the obese population are gender-dependent

scientific article published on 26 August 2014

The metabolome-wide association study: a new look at human disease risk factors.

scientific article published on 16 August 2008

The nPYc-Toolbox, a Python module for the pre-processing, quality-control and analysis of metabolic profiling datasets

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The pathophysiology of human obstructive cholestasis is mimicked in cholestatic Gold Syrian hamsters.

scientific article published on 28 November 2017

The potential of 19F NMR spectroscopy for rapid screening of cell cultures for models of mammalian drug metabolism

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The promise of metabolic phenotyping in gastroenterology and hepatology

scientific article published on 21 July 2015

The role of gut microbiota in drug response.

scientific article published in January 2009

Therapeutic modulation of microbiota-host metabolic interactions.

scientific article published on June 2012

Top-down systems biology integration of conditional prebiotic modulated transgenomic interactions in a humanized microbiome mouse model

scientific article published on 15 July 2008

Top-down systems biology modeling of host metabotype-microbiome associations in obese rodents

scientific article published in May 2009

Topics in Xenobiochemistry: Do metabolic pathways exist for xenobiotics? The micro-metabolism hypothesis ⬇️

scientific article published on September 1, 2003

Topographical variation in metabolic signatures of human gastrointestinal biopsies revealed by high-resolution magic-angle spinning 1H NMR spectroscopy

scientific article published on 21 August 2007

Topographical variation in murine intestinal metabolic profiles in relation to microbiome speciation and functional ecological activity.

scientific article published in July 2009

Topological analysis of metabolic networks integrating co-segregating transcriptomes and metabolomes in type 2 diabetic rat congenic series

scientific article published on 30 September 2016

Toxicity classification from metabonomic data using a density superposition approach: ‘CLOUDS’

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Transgenomic metabolic interactions in a mouse disease model: interactions of Trichinella spiralis infection with dietary Lactobacillus paracasei supplementation

scientific article published in September 2006

Translational utility of a hierarchical classification strategy in biomolecular data analytics.

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UPLC-MS, HPLC-radiometric, and NMR-spectroscopic studies on the metabolic fate of 3-fluoro-[U-14C]-aniline in the bile-cannulated rat.

scientific article published in July 2010

UPLC/MS(E); a new approach for generating molecular fragment information for biomarker structure elucidation

scientific article published in January 2006

UPLC/MSE; a new approach for generating molecular fragment information for biomarker structure elucidation

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Ultra high field NMR spectroscopic studies on human seminal fluid, seminal vesicle and prostatic secretions

scientific article published on 01 January 1994

Ultra performance liquid chromatography-mass spectrometry profiling of bile acid metabolites in biofluids: application to experimental toxicology studies.

scientific article published in June 2010

Ultra-Performance Liquid Chromatography-High-Resolution Mass Spectrometry and Direct Infusion-High-Resolution Mass Spectrometry for Combined Exploratory and Targeted Metabolic Profiling of Human Urine

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Ultrahigh-Performance Liquid Chromatography Tandem Mass Spectrometry with Electrospray Ionization Quantification of Tryptophan Metabolites and Markers of Gut Health in Serum and Plasma-Application to Clinical and Epidemiology Cohorts

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Understanding 'Global' Systems Biology: Metabonomics and the Continuum of Metabolism

Understanding the role of gut microbiome-host metabolic signal disruption in health and disease

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Unmet Medical Needs

Untargeted Mass Spectrometry Lipidomics identifies correlation between serum sphingomyelins and plasma cholesterol

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Untargeted Metabolome Quantitative Trait Locus Mapping Associates Variation in Urine Glycerate to Mutant Glycerate Kinase

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Untargeted UPLC-MS profiling pipeline to expand tissue metabolome coverage: application to cardiovascular disease

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Urinary Metabolic Phenotyping of Women with Lower Urinary Tract Symptoms.

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Urinary metabolic phenotyping differentiates children with autism from their unaffected siblings and age-matched controls

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Urinary metabolic phenotyping for Alzheimer’s disease

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Urinary metabolic phenotyping the slc26a6 (chloride-oxalate exchanger) null mouse model

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Urinary metabolic signatures of human adiposity

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Urinary metabolites of 2-bromoethanamine identified by stable isotope labelling: evidence for carbamoylation and glutathione conjugation

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Urinary phenotyping indicates weight loss-independent metabolic effects of Roux-en-Y gastric bypass in mice.

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Uroscopy in the 21st century: high-field NMR spectroscopy.

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Use of an Atmospheric Solids Analysis Probe (ASAP) for High Throughput Screening of Biological Fluids: Preliminary Applications on Urine and Bile

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Use of high-field nuclear magnetic resonance spectroscopy for the analysis of biological fluids

Use of metabonomics to identify impaired fatty acid metabolism as the mechanism of a drug-induced toxicity

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Use of relaxation-edited one-dimensional and two dimensional nuclear magnetic resonance spectroscopy to improve detection of small metabolites in blood plasma

scientific article published in February 2004

Use of1H NMR-determined diffusion coefficients to characterize lipoprotein fractions in human blood plasma

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Vaginal dysbiosis increases risk of preterm fetal membrane rupture, neonatal sepsis and is exacerbated by erythromycin

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Variation in Antibiotic-Induced Microbial Recolonization Impacts on the Host Metabolic Phenotypes of Rats

scientific article published on 29 June 2011

Variation in Gut Microbiota Strongly Influences Individual Rodent Phenotypes

scientific article published on 01 September 2005

Virtual Chromatographic Resolution Enhancement in Cryoflow LC−NMR Experiments via Statistical Total Correlation Spectroscopy

scientific article published on 30 March 2007

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Weaning diet induces sustained metabolic phenotype shift in the pig and influences host response to Bifidobacterium lactis NCC2818

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XCMS-MRM and METLIN-MRM: a cloud library and public resource for targeted analysis of small molecules

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mQTL.NMR: an integrated suite for genetic mapping of quantitative variations of (1)H NMR-based metabolic profiles

scientific article published on 2 April 2015

pJRES Binning Algorithm (JBA): a new method to facilitate the recovery of metabolic information from pJRES 1H NMR spectra

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¹H NMR-based metabonomics for investigating diabetes

scientific article published on July 2009

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