List of works - Georgia Chenevix-Trench

Mutations of the BRAF gene in human cancer

scientific article (publication date: 27 June 2002)

Patterns of somatic mutation in human cancer genomes

scientific article (publication date: 8 March 2007)

Genome-wide association study identifies novel breast cancer susceptibility loci

scientific article published on 28 June 2007

Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome

scientific article

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

scientific article

Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies

scientific article

Lung cancer: intragenic ERBB2 kinase mutations in tumours

scientific article

A common coding variant in CASP8 is associated with breast cancer risk

article

Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2.

scientific article published on 29 March 2009

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

scientific article published on April 2013

Genome-wide association studies identify four ER negative-specific breast cancer risk loci

scientific article published in April 2013

Gene-panel sequencing and the prediction of breast-cancer risk

scientific article

Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancer

scientific article

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

scientific article

Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics

scientific article

Association analysis identifies 65 new breast cancer risk loci

scientific article published on 23 October 2017

A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.

scientific article published on 19 September 2010

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

scientific article published on April 2013

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

scientific article

A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2.

scientific article

Prediction of breast cancer risk based on profiling with common genetic variants

scientific article published on 8 April 2015

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

scientific article

Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

scientific article published on 5 December 2011

Genome-wide association analysis identifies three new breast cancer susceptibility loci

scientific article published on 22 January 2012

Common variants at 19p13 are associated with susceptibility to ovarian cancer

scientific article

Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study

scientific article

RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies

scientific article published on 16 October 2007

Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article

Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk

scientific article (publication date: 2013)

Dominant Negative ATM Mutations in Breast Cancer Families

scientific article

Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer

scientific article

A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia

scientific article

Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers

scientific article published on 27 March 2013

Identification of six new susceptibility loci for invasive epithelial ovarian cancer

scientific article published on 12 January 2015

Nevoid basal cell carcinoma syndrome: review of 118 affected individuals

scientific article published on April 1994

Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium

scientific article

Frequent PTEN/MMAC mutations in endometrioid but not serous or mucinous epithelial ovarian tumors.

scientific article published in May 1998

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

scientific article published in November 2015

Incessant ovulation, inflammation and epithelial ovarian carcinogenesis: revisiting old hypotheses

scientific article published on 16 November 2005

Rare variants in the ATM gene and risk of breast cancer

scientific article published on 25 July 2011

Genetic and Histopathologic Evaluation ofBRCA1andBRCA2DNA Sequence Variants of Unknown Clinical Significance

article

Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction

scientific article

Medulloblastomas of the desmoplastic variant carry mutations of the human homologue of Drosophila patched.

scientific article published on June 1997

The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers

scientific article published on 03 October 2016

Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer

scientific article published in 2013

Rare, evolutionarily unlikely missense substitutions in ATM confer increased risk of breast cancer

scientific article published on 24 September 2009

An international initiative to identify genetic modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers: the Consortium of Investigators of Modifiers of BRCA1 and BRCA2 (CIMBA)

scientific article

Genetic determinants of telomere length and risk of common cancers: a Mendelian randomization study

scientific article

Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer risk

scientific article published on 27 March 2013

Isolation and characterization of human patched 2 (PTCH2), a putative tumour suppressor gene inbasal cell carcinoma and medulloblastoma on chromosome 1p32.

scientific article

List of works by Georgia Chenevix-Trench

Mutations of the BRAF gene in human cancer

Patterns of somatic mutation in human cancer genomes

Genome-wide association study identifies novel breast cancer susceptibility loci

Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies

Lung cancer: intragenic ERBB2 kinase mutations in tumours

A common coding variant in CASP8 is associated with breast cancer risk

Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2.

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

Genome-wide association studies identify four ER negative-specific breast cancer risk loci

Gene-panel sequencing and the prediction of breast-cancer risk

Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancer

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics

Association analysis identifies 65 new breast cancer risk loci

A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2.

Prediction of breast cancer risk based on profiling with common genetic variants

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

Genome-wide association analysis identifies three new breast cancer susceptibility loci

Common variants at 19p13 are associated with susceptibility to ovarian cancer

Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study

RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies

Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers

Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk

Dominant Negative ATM Mutations in Breast Cancer Families

Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer

A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia

Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers

Identification of six new susceptibility loci for invasive epithelial ovarian cancer

Nevoid basal cell carcinoma syndrome: review of 118 affected individuals

Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium

Frequent PTEN/MMAC mutations in endometrioid but not serous or mucinous epithelial ovarian tumors.

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

Incessant ovulation, inflammation and epithelial ovarian carcinogenesis: revisiting old hypotheses

Rare variants in the ATM gene and risk of breast cancer

Genetic and Histopathologic Evaluation ofBRCA1andBRCA2DNA Sequence Variants of Unknown Clinical Significance

Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction

Medulloblastomas of the desmoplastic variant carry mutations of the human homologue of Drosophila patched.

The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers

Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer

Rare, evolutionarily unlikely missense substitutions in ATM confer increased risk of breast cancer

An international initiative to identify genetic modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers: the Consortium of Investigators of Modifiers of BRCA1 and BRCA2 (CIMBA)

Genetic determinants of telomere length and risk of common cancers: a Mendelian randomization study

Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer risk

Isolation and characterization of human patched 2 (PTCH2), a putative tumour suppressor gene inbasal cell carcinoma and medulloblastoma on chromosome 1p32.