Search filters

List of works by Matthias Blüher

(Epi)genetic regulation of CRTC1 in human eating behaviour and fat distribution

scientific article published on 30 May 2019

12-Lipoxygenase Regulates Cold Adaptation and Glucose Metabolism by Producing the Omega-3 Lipid 12-HEPE from Brown Fat

scientific article published on 25 July 2019

A Green-Mediterranean Diet, Supplemented with Mankai Duckweed, Preserves Iron-Homeostasis in Humans and Is Efficient in Reversal of Anemia in Rats

scientific article published on 01 June 2019

A Hepatic GAbp-AMPK Axis Links Inflammatory Signaling to Systemic Vascular Damage

scientific article published on August 2017

A Human REPIN1 Gene Variant: Genetic Risk Factor for the Development of Nonalcoholic Fatty Liver Disease

scientific article published on 01 January 2020

A SNP haplotype of the forkhead transcription factor FOXO1A gene may have a protective effect against type 2 diabetes in German Caucasians

scientific article published on 6 June 2007

A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function

scientific article published in September 2017

A TRAIL-TL1A Paracrine Network Involving Adipocytes, Macrophages and lymphocytes Induces Adipose Tissue Dysfunction Downstream of E2F1 in Human Obesity

scientific article published on 30 July 2020

A collective diabetes cross in combination with a computational framework to dissect the genetics of human obesity and Type 2 diabetes

scientific article published on 01 September 2018

A common variant of PNPLA3 (p.I148M) is not associated with alcoholic chronic pancreatitis

scientific article

A computational biology approach of a genome-wide screen connected miRNAs to obesity and type 2 diabetes

scientific article published on 15 March 2018

A miR-29a-driven negative feedback loop regulates peripheral glucocorticoid receptor signaling

scientific article published on 11 February 2019

A microRNA screen reveals that elevated hepatic ectodysplasin A expression contributes to obesity-induced insulin resistance in skeletal muscle

scientific article

A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism

scientific journal article

A novel thermoregulatory role for PDE10A in mouse and human adipocytes

scientific article published on 31 May 2016

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

scientific article published on 23 November 2016

A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity

scientific article published on 17 April 2017

A tissue-specific screen of ceramide expression in aged mice identifies ceramide synthase-1 and ceramide synthase-5 as potential regulators of fiber size and strength in skeletal muscle

scientific article published on 06 November 2019

ADCY5 gene expression in adipose tissue is related to obesity in men and mice

scientific article

ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotype

scientific article

Abdominal subcutaneous fat quantification in obese patients from limited field-of-view MRI data

scientific article published on 04 November 2020

Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance

scientific article published on 6 January 2013

Ablation of kallikrein 7 (KLK7) in adipose tissue ameliorates metabolic consequences of high fat diet-induced obesity by counteracting adipose tissue inflammation in vivo

scientific article published on 20 September 2017

Access to gram scale amounts of functional globular adiponectin from E. coli inclusion bodies by alkaline-shock solubilization

scientific article published on 10 June 2010

Accumulation of distinct persistent organic pollutants is associated with adipose tissue inflammation

scientific article published on 23 September 2020

Activated Ask1-MKK4-p38MAPK/JNK Stress Signaling Pathway in Human Omental Fat Tissue May Link Macrophage Infiltration to Whole-Body Insulin Sensitivity.

scientific article

Activated Ask1-MKK4-p38MAPK/JNK stress signaling pathway in human omental fat tissue may link macrophage infiltration to whole-body Insulin sensitivity

scientific article

Active integrins regulate white adipose tissue insulin sensitivity and brown fat thermogenesis

scientific article published on 21 December 2020

Adenosine/A2B Receptor Signaling Ameliorates the Effects of Aging and Counteracts Obesity

scientific article published on 22 June 2020

Adipocyte dysfunction, inflammation and metabolic syndrome

scientific article

Adipocyte fatty acid-binding protein levels are associated with left ventricular diastolic dysfunction in morbidly obese subjects

scientific article published on 10 February 2014

Adipocyte size threshold matters: link with risk of type 2 diabetes and improved insulin resistance after gastric bypass

scientific article published on 29 April 2014

Adipocyte-Specific Hypoxia-Inducible Factor 2α Deficiency Exacerbates Obesity-Induced Brown Adipose Tissue Dysfunction and Metabolic Dysregulation

scientific article

Adipocytokines are not associated with gestational diabetes mellitus but with pregnancy status

scientific article published on 10 April 2020

Adipokine Pattern in Subjects with Impaired Fasting Glucose and Impaired Glucose Tolerance in Comparison to Normal Glucose Tolerance and Diabetes

scientific article published on November 9, 2010

Adipokines - removing road blocks to obesity and diabetes therapy

scientific article

Adipokines and adipocyte targets in the future management of obesity and the metabolic syndrome

scientific article published on January 2007

Adipokines in diabetes and cardiovascular diseases

scientific article published on September 2007

Adipokines in gestational diabetes

scientific article published on 30 December 2013

Adipokines in health and disease

scientific article published on 25 May 2015

Adipokines influencing metabolic and cardiovascular disease are differentially regulated in maintenance hemodialysis

scientific article

Adiponectin expression in humans is dependent on differentiation of adipocytes and down-regulated by humoral serum components of high molecular weight

scientific article published on 22 September 2005

Adiponectin gene expression and secretion is inhibited by interleukin-6 in 3T3-L1 adipocytes

scientific article published on February 2003

Adiponectin promotes the migration of circulating angiogenic cells through p38-mediated induction of the CXCR4 receptor

scientific article published on 07 June 2012

Adipose dipeptidyl peptidase-4 and obesity: correlation with insulin resistance and depot-specific release from adipose tissue in vivo and in vitro

scientific article published on 15 October 2013

Adipose tissue depot specific promoter methylation of TMEM18.

scientific article published on 26 April 2014

Adipose tissue derived bacteria are associated with inflammation in obesity and type 2 diabetes

scientific article published on 21 April 2020

Adipose tissue dysfunction contributes to obesity related metabolic diseases

scientific article published on 06 March 2013

Adipose tissue dysfunction in obesity

scientific article

Adipose tissue expression and genetic variants of the bone morphogenetic protein receptor 1A gene (BMPR1A) are associated with human obesity

scientific article published on 05 June 2009

Adipose tissue foam cells are present in human obesity

scientific article published on 31 January 2013

Adipose tissue inflammation: a cause or consequence of obesity-related insulin resistance?

scientific article

Adipose tissue retains an epigenetic memory of obesity after weight loss

scientific article published on 18 November 2024

Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance

scientific article

Adipose triglyceride lipase gene expression in human visceral obesity

scientific article published on 10 December 2007

Adipsin is an adipokine that improves β cell function in diabetes

scientific article

Age and gender specific estimation of visceral adipose tissue amounts from radiological images in morbidly obese patients

scientific article published on 24 March 2016

Altered Autophagy in Human Adipose Tissues in Obesity.

scientific article

Altered autophagy in human adipose tissues in obesity

scientific article published on 03 November 2010

Altered fiber distribution and fiber-specific glycolytic and oxidative enzyme activity in skeletal muscle of patients with type 2 diabetes

scientific article published on 01 April 2006

Altered sciatic nerve fiber morphology and endoneural microvessels in mouse models relevant for obesity, peripheral diabetic polyneuropathy, and the metabolic syndrome

scientific article

Amyloid precursor protein expression is induced by tumor necrosis factor alpha in 3T3-L1 adipocytes

scientific article published on December 2009

An ACACB variant implicated in diabetic nephropathy associates with body mass index and gene expression in obese subjects

scientific article

An AMP-activated protein kinase-stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice

scientific article published on 29 August 2016

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

scientific article published on 31 May 2017

An MRM-Based Multiplexed Quantification Assay for Human Adipokines and Apolipoproteins

scientific article published on 11 February 2020

An inflammatory micro-environment promotes human adipocyte apoptosis

scientific article published on 9 April 2011

Analysis of a rare functional truncating mutation rs61757459 in vaspin (SERPINA12) on circulating vaspin levels

scientific article published on 12 June 2013

Analysis of the Relationship between PPAR-γ 2 Gene Variants and Severe Insulin Resistance in Obese Patients with Impaired Glucose Tolerance

scientific article published on April 1, 2003

Analysis of the relationship between the Pro12Ala variant in the PPAR-gamma2 gene and the response rate to therapy with pioglitazone in patients with type 2 diabetes

scientific article

Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by Cdk5.

scientific article

Apolipoprotein E allele frequencies in chronic and self-limited hepatitis C suggest a protective effect of APOE4 in the course of hepatitis C virus infection

scientific article

Are metabolically healthy obese individuals really healthy?

scientific article published on 10 July 2014

Are there still healthy obese patients?

scientific article published on October 1, 2012

Association between plasma nonesterified fatty acids species and adipose tissue fatty acid composition

scientific article

Association of Glypican-4 With Body Fat Distribution, Insulin Resistance, and Nonalcoholic Fatty Liver Disease

scientific article published on April 30, 2013

Association of interleukin-6, C-reactive protein, interleukin-10 and adiponectin plasma concentrations with measures of obesity, insulin sensitivity and glucose metabolism

scientific article published in October 2005

Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance

scientific article

Atg7 Knockdown Reduces Chemerin Secretion in Murine Adipocytes

scientific article published on 01 November 2019

Attitudes and treatment practice of general practitioners towards patients with obesity in primary care

scientific article published on 17 August 2020

Autocrine IGF-1 action in adipocytes controls systemic IGF-1 concentrations and growth

scientific article published on 28 April 2008

Autophagy determines efficiency of liver-directed gene therapy with adeno-associated viral vectors

scientific article published on 20 March 2017

Autophagy in adipose tissue

scientific article published on 18 October 2012

Autophagy in adipose tissue of patients with obesity and type 2 diabetes

scientific article published on 26 March 2015

B Lymphocyte Stimulator (BLyS) is expressed in human adipocytes in vivo and is related to obesity but not to insulin resistance

scientific article

Beneficial effects of a 4-week exercise program on plasma concentrations of adhesion molecules

scientific article published on 01 March 2007

Betatrophin levels are increased in women with gestational diabetes mellitus compared to healthy pregnant controls

scientific article published on 07 April 2015

Bone morphogenetic protein 2 (BMP2) may contribute to partition of energy storage into visceral and subcutaneous fat depots

scientific article

Brown adipose tissue (BAT) specific vaspin expression is increased after obesogenic diets and cold exposure and linked to acute changes in DNA-methylation

scientific article

C57BL/6JRj mice are protected against diet induced obesity (DIO).

scientific article published on 8 December 2011

COL6A3 expression in adipocytes associates with insulin resistance and depends on PPARγ and adipocyte size

scientific article published on 10 April 2014

COL6A3 expression in adipose tissue cells is associated with levels of the homeobox transcription factor PRRX1

scientific article published on 19 November 2020

COMP-Ang-1 Improves Glucose Uptake in db/db Mice with Type 2 Diabetes

scientific article published on 06 April 2020

COMP-angiopoietin-1 recovers molecular biomarkers of neuropathy and improves vascularisation in sciatic nerve of ob/ob mice

scientific article

Carbonylated plasma proteins as potential biomarkers of obesity induced type 2 diabetes mellitus.

scientific article

Central noradrenaline transporter availability in highly obese, non-depressed individuals

scientific article published on 9 January 2017

Central noradrenaline transporter availability is linked with HPA axis responsiveness and copeptin in human obesity and non-obese controls

scientific article published on 29 October 2018

Central serotonin transporter availability in highly obese individuals compared with non-obese controls: A [(11)C] DASB positron emission tomography study

scientific article published on 18 November 2015

Central vaspin administration acutely reduces food intake and has sustained blood glucose-lowering effects

scientific article published on 5 April 2011

Changes in body weight after 24 weeks of vildagliptin therapy as a function of fasting glucose levels in patients with type 2 diabetes

scientific article

Changes in systemic and subcutaneous adipose tissue inflammation and oxidative stress in response to exercise training in obese black African women

scientific article published on 19 January 2020

Changes of renal sinus fat and renal parenchymal fat during an 18-month randomized weight loss trial

scientific article published on 02 May 2017

Characterization of chemical-induced sterile inflammation in vitro: application of the model compound ketoconazole in a human hepatic co-culture system

scientific article published on 10 March 2016

Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis

scientific article

Circulating Adipokine VASPIN Is Associated with Serum Lipid Profiles in Humans

scientific article published on 18 March 2019

Circulating Nampt and RBP4 levels in patients with carotid stenosis undergoing carotid endarterectomy (CEA)

scientific article published on March 21, 2011

Circulating Pro-Neurotensin in gestational diabetes mellitus

scientific article published on 20 October 2018

Circulating adipocyte fatty acid binding protein is increased in chronic and acute renal dysfunction

scientific article

Circulating adiponectin and expression of adiponectin receptors in human skeletal muscle: associations with metabolic parameters and insulin resistance and regulation by physical training

scientific article

Circulating anandamide and blood pressure in patients with obstructive sleep apnea

scientific article published in December 2012

Circulating and Adipose Tissue Fatty Acid Composition in Black South African Women with Obesity: A Cross-Sectional Study

scientific article published on 31 May 2020

Circulating angiopoietin-like protein 8 is independently associated with fasting plasma glucose and type 2 diabetes mellitus

scientific article published on December 2014

Circulating bacterial signature is linked to metabolic disease and shifts with metabolic alleviation after bariatric surgery

scientific article published on 22 June 2021

Circulating cell adhesion molecules in metabolically healthy obesity

scientific article published on 01 September 2020

Circulating chemerin decreases in response to a combined strength and endurance training

scientific article published on June 20, 2013

Circulating endocannabinoids and N-acyl-ethanolamides in patients with sleep apnea--specific role of oleoylethanolamide

scientific article published on 28 April 2010

Circulating high-molecular-weight adiponectin is upregulated in preeclampsia and is related to insulin sensitivity and renal function

scientific article published on February 2008

Circulating levels of the adipokine chemerin in gestational diabetes mellitus

scientific article published on 29 April 2010

Circulating progranulin but not renal progranulin expression is increased in renal dysfunction

scientific article published in November 2015

Clinical Relevance of Adipokines

scientific article published on October 18, 2012

Clinical inertia in individualising care for diabetes: is there time to do more in type 2 diabetes?

scientific article

Clinical trial simulation methods for estimating the impact of DPP-4 inhibitors on cardiovascular disease

scientific article published on 5 June 2015

Combined Proteomic and Metabolomic Profiling of Serum Reveals Association of the Complement System with Obesity and Identifies Novel Markers of Body Fat Mass Changes

scientific article published on August 29, 2011

Comparison of T1 relaxation times in adipose tissue of severely obese patients and healthy lean subjects measured by 1.5 T MRI.

scientific article published on 26 July 2014

Complete analysis of the human mesotrypsinogen gene (PRSS3) in patients with chronic pancreatitis

scientific article

Consequences of Obesity on the Sense of Taste: Taste Buds as Treatment Targets?

scientific article published on 11 May 2020

Control of diabetic hyperglycaemia and insulin resistance through TSC22D4.

scientific article

Correction to: Intravenous Ferric Carboxymaltose in Patients with Type 2 Diabetes Mellitus and Iron Deficiency: CLEVER Trial Study Design and Protocol

scientific article published on 01 February 2019

Correction to: Preoperative Upper-GI Endoscopy Prior to Bariatric Surgery: Essential or Optional?

scientific article published on 20 April 2020

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Corrigendum: The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue.

scientific article published in November 2017

Current NAFLD guidelines for risk stratification in diabetic patients have poor diagnostic discrimination

scientific article published on 27 October 2020

Cytokine Gene Expression in Autoimmune Thyroiditis in BioBreeding/Worcester Rats

article

DNA 5-hydroxymethylation in human adipose tissue differs between subcutaneous and visceral adipose tissue depots

scientific article

DNA methylation of SSPN is linked to adipose tissue distribution and glucose metabolism

scientific article published on 22 June 2018

DNA methylation patterns reflect individual's lifestyle independent of obesity

scientific article published on 01 June 2022

DNA methylation signature in blood mirrors successful weight-loss during lifestyle interventions: the CENTRAL trial

scientific article published on 16 November 2020

Dairy calcium intake, serum vitamin D, and successful weight loss

scientific article

Decreased adiponectin links elevated adipose tissue autophagy with adipocyte endocrine dysfunction in obesity

scientific article published on 20 January 2016

Defective peripheral nerve development is linked to abnormal architecture and metabolic activity of adipose tissue in Nscl-2 mutant mice

scientific article

Defining the human adipose tissue proteome to reveal metabolic alterations in obesity

scientific article published on 25 September 2014

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Development of a mouse IgA monoclonal antibody-based enzyme-linked immunosorbent sandwich assay for the analyses of RBP4.

scientific article published on 7 February 2018

Development of diabetes in obese, insulin-resistant mice: essential role of dietary carbohydrate in beta cell destruction

article

Developmentally Driven Changes in Adipogenesis in Different Fat Depots Are Related to Obesity

scientific article published on 26 March 2020

Di-(2-Ethylhexyl)-Phthalate (DEHP) Causes Impaired Adipocyte Function and Alters Serum Metabolites

scientific article (publication date: 2015)

Diagnostic Accuracy of Protein Glycation Sites in Long-Term Controlled Patients with Type 2 Diabetes Mellitus and Their Prognostic Potential for Early Diagnosis.

scientific article published on 30 April 2018

Dietary intervention induces flow of changes within biomarkers of lipids, inflammation, liver enzymes, and glycemic control

scientific article

Dietary intervention to reverse carotid atherosclerosis

scientific article published on March 2010

Different associations of adipokines in lean and healthy adults

scientific article published on 16 September 2013

Differential Expression of Novel Adiponectin Receptor-1 Transcripts in Skeletal Muscle of Subjects With Normal Glucose Tolerance and Type 2 Diabetes

scientific article published on February 2, 2011

Differential regulation of visfatin and adiponectin in pregnancies with normal and abnormal placental function

scientific article published on 01 March 2007

Dimerization of adiponectin receptor 1 is inhibited by adiponectin

scientific article published on 23 March 2010

Direct evidence of brown adipocytes in different fat depots in children

scientific article

Distinct abdominal and gluteal adipose tissue transcriptome signatures are altered by exercise training in African women with obesity

scientific article published on 24 June 2020

Distinct roles of angiopoietin-like 4 in the regulation of central and peripheral lipid metabolism?

scientific article published on 13 December 2014

Does retinol-binding protein 4 cause or reflect fatty liver disease?

scientific article published on 01 July 2008

Does vitamin D supplementation alter plasma adipokines concentrations? A systematic review and meta-analysis of randomized controlled trials

scientific article published on 30 March 2016

Dynamics of intrapericardial and extrapericardial fat tissues during long-term, dietary-induced, moderate weight loss

scientific article

Dysregulation of the peripheral and adipose tissue endocannabinoid system in human abdominal obesity

scientific article

EHD2-mediated restriction of caveolar dynamics regulates cellular fatty acid uptake

scientific article published on 13 March 2020

Effect of Distinct Lifestyle Interventions on Mobilization of Fat Storage Pools: The CENTRAL MRI Randomized Controlled Trial

scientific article published on 15 November 2017

Effect of a 4 week physical training program on plasma concentrations of inflammatory markers in patients with abnormal glucose tolerance

scientific article published in April 2006

Effect of genetic variation in the human fatty acid synthase gene (FASN) on obesity and fat depot-specific mRNA expression

scientific article published on 29 October 2009

Effect of wine on carotid atherosclerosis in type 2 diabetes: a 2-year randomized controlled trial

scientific article published on 29 January 2018

Effects of Diet-Modulated Autologous Fecal Microbiota Transplantation on Weight Regain

scientific article published on 26 August 2020

Effects of Initiating Moderate Alcohol Intake on Cardiometabolic Risk in Adults With Type 2 Diabetes: A 2-Year Randomized, Controlled Trial

scientific article

Effects of Supervised vs Non-Supervised Combined Aerobic and Resistance Exercise Programme on Cardiometabolic Risk Factors

scientific article published on March 1, 2013

Effects of Weight Loss on Glutathione Peroxidase 3 Serum Concentrations and Adipose Tissue Expression in Human Obesity

Effects of a 2-y dietary weight-loss intervention on cholesterol metabolism in moderately obese men.

scientific article published on 21 September 2011

Effects of body weight reduction on blood adipokines and subcutaneous adipose tissue adipokine mRNA expression profiles in obese ponies

scientific article published on October 7, 2012

Effects of exercise on ACE2

scientific article published on 17 September 2020

Effects of extended-release niacin on lipid profile and adipocyte biology in patients with impaired glucose tolerance

scientific article published on 3 December 2008

Effects of genetic variation in the human retinol binding protein-4 gene (RBP4) on insulin resistance and fat depot-specific mRNA expression

scientific article published on 29 August 2007

Effects of hyperthyroidism on adipose tissue activity and distribution in adults

scientific article published on 06 October 2020

Effects of initiating moderate wine intake on abdominal adipose tissue in adults with type 2 diabetes: a 2-year randomized controlled trial

scientific article

Effects of isoflurane anesthesia on F-waves in the sciatic nerve of the adult rat.

scientific article published on 5 May 2014

Effects of physical exercise versus rosiglitazone on endothelial function in coronary artery disease patients with prediabetes

scientific article published on September 2010

Effects of weight loss and exercise on apelin serum concentrations and adipose tissue expression in human obesity

scientific article published on 21 February 2013

Effects of weight loss and exercise on chemerin serum concentrations and adipose tissue expression in human obesity

scientific article published on 2 December 2011

Efficacy and Safety of Cathine (Nor-Pseudoephedrine) in the Treatment of Obesity: A Randomized Dose-Finding Study

scientific article published on 6 September 2017

Efficacy and safety of the weight-loss drug rimonabant

scientific article

Efficacy and safety of vildagliptin in clinical practice-results of the PROVIL-study

scientific article published on September 15, 2012

Elevated Plasma Levels of 3-Hydroxyisobutyric Acid Are Associated With Incident Type 2 Diabetes

scientific article

Elevated autophagy gene expression in adipose tissue of obese humans: A potential non-cell-cycle-dependent function of E2F1.

scientific article published on 22 September 2015

Endocrine disrupting chemicals affect the adipogenic differentiation of mesenchymal stem cells in distinct ontogenetic windows

scientific article published on December 16, 2011

Endogenous soluble receptor for advanced glycation endproducts is increased in preeclampsia

scientific article published on September 2008

Endoscopic treatment of obesity and complications following bariatric surgery

scientific article published in August 2016

Enzymatic Activity of HPGD in Treg Cells Suppresses Tconv Cells to Maintain Adipose Tissue Homeostasis and Prevent Metabolic Dysfunction

scientific article published on 23 April 2019

Estimation of abdominal subcutaneous fat volume of obese adults from single-slice MRI data - Regression coefficients and agreement

scientific article published on 15 July 2020

Evidence for a role of developmental genes in the origin of obesity and body fat distribution

scholarly article

Evidence of early alterations in adipose tissue biology and function and its association with obesity-related inflammation and insulin resistance in children

scientific article

Exercise Training Alters Red Blood Cell Fatty Acid Desaturase Indices and Adipose Tissue Fatty Acid Profile in African Women with Obesity

scientific article published on 06 July 2020

Exercise training restores the endothelial response to vascular growth factors in patients with stable coronary artery disease

scientific article published on March 22, 2011

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

scientific article published on 06 June 2019

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

scientific article published on 01 September 2019

Expression of anti-inflammatory macrophage genes within skeletal muscle correlates with insulin sensitivity in human obesity and type 2 diabetes

scientific article published on April 18, 2013

Extended longevity and insulin signaling in adipose tissue

scientific article

Extended longevity in mice lacking the insulin receptor in adipose tissue

scientific article (publication date: 24 January 2003)

Extensive weight loss reveals distinct gene expression changes in human subcutaneous and visceral adipose tissue

scientific article

Extracellular fatty acid synthase: a possible surrogate biomarker of insulin resistance

scientific article

FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis

scientific article published on 17 March 2020

FSTL3 is increased in renal dysfunction

scientific article published on 3 March 2017

Fas (CD95) expression in myeloid cells promotes obesity‐induced muscle insulin resistance

scientific article published on January 2014

Fas and Fas ligand gene expression in autoimmune thyroiditis in BB/W rats

article

Fas and FasL expression in human adipose tissue is related to obesity, insulin resistance, and type 2 diabetes

scientific article published on 20 December 2013

Fasting-induced liver GADD45β restrains hepatic fatty acid uptake and improves metabolic health

scientific article published on 03 May 2016

Fat depot-specific expression of HOXC9 and HOXC10 may contribute to adverse fat distribution and related metabolic traits

scientific article published on 9 December 2015

Fat depot-specific mRNA expression of novel loci associated with waist-hip ratio

scientific article published on 19 April 2013

Fatty acid synthase gene expression in human adipose tissue: association with obesity and type 2 diabetes

scientific article published on 11 May 2007

Feasibility and Safety of Bariatric Surgery in High-Risk Patients: A Single-Center Experience.

scientific article published on 14 January 2018

Fibroblast growth factor 19 serum levels: relation to renal function and metabolic parameters

scientific article published on 14 December 2009

Fibroblast growth factor-21 serum concentrations are associated with metabolic and hepatic markers in humans

scientific article published on 18 January 2013

Five A's counseling in weight management of obese patients in primary care: a cluster-randomized controlled trial (INTERACT).

scientific article

Five-Year Outcomes of Gastric Bypass in Adolescents as Compared with Adults

scientific article published on 01 August 2019

Free fatty acids sensitize dendritic cells to amplify TH1/TH17-immune responses

scientific article

From leptin to other adipokines in health and disease: facts and expectations at the beginning of the 21st century

scientific article

Functional relevance of genes implicated by obesity genome-wide association study signals for human adipocyte biology

scientific article published on 16 November 2012

GH is a positive regulator of tumor necrosis factor alpha-induced adipose related protein in 3T3-L1 adipocytes

scientific article published on September 2003

GIP receptor mRNA expression in different fat tissue depots in postmenopausal non-diabetic women.

scientific article published on 23 February 2007

Gender differences of adiponectin levels develop during the progression of puberty and are related to serum androgen levels

scientific article

Gene expression of PPARgamma and PGC-1alpha in human omental and subcutaneous adipose tissues is related to insulin resistance markers and mediates beneficial effects of physical training

scientific article

Gene expression of adiponectin receptors in human visceral and subcutaneous adipose tissue is related to insulin resistance and metabolic parameters and is altered in response to physical training

scientific article published on 18 September 2007

Gene expression profiling in adipose tissue of Sprague Dawley rats identifies olfactory receptor 984 as a potential obesity treatment target

article

Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity

scientific article published on 11 September 2020

Genetic analyses of heme oxygenase 1 (HMOX1) in different forms of pancreatitis

scientific article

Genetic and biochemical evidence for a functional role of BACE1 in the regulation of insulin mRNA expression

scientific article published on 5 July 2013

Genetic and evolutionary analyses of the human bone morphogenetic protein receptor 2 (BMPR2) in the pathophysiology of obesity

scientific article

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

scientific article

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genetic variation in GPR133 is associated with height: genome wide association study in the self-contained population of Sorbs

scientific article published on 03 September 2009

Genetic variation in sodium-glucose cotransporter 2 and heart failure

scientific article published on 06 January 2021

Genetic variation in the vaspin gene affects circulating serum vaspin concentrations

scientific article published on 21 August 2012

Genetic variation in the visfatin gene (PBEF1) and its relation to glucose metabolism and fat-depot-specific messenger ribonucleic acid expression in humans

scientific article published on 24 April 2006

Genetics and epigenetics in obesity

article

Genome wide meta-analysis highlights the role of genetic variation in RARRES2 in the regulation of circulating serum chemerin

scientific article

Genome wide meta-analysis identifies novel determinants of circulating serum progranulin

scientific article published on 27 November 2017

Genome-wide DNA promoter methylation and transcriptome analysis in human adipose tissue unravels novel candidate genes for obesity

scientific article

Genomic insights into the origin of farming in the ancient Near East

scientific article (publication date: 25 August 2016)

Global DNA methylation levels in human adipose tissue are related to fat distribution and glucose homeostasis

scientific article published on 22 August 2014

Glucose concentration and AMP-dependent kinase activation regulate expression of insulin receptor family members in rat islets and INS-1E beta cells

scientific article

Glucose regulates expression of the nerve growth factor (NGF) receptors TrkA and p75NTR in rat islets and INS-1E beta-cells

scientific article published on 27 April 2006

Glycated lysine-141 in haptoglobin improves the diagnostic accuracy for type 2 diabetes mellitus in combination with glycated hemoglobin HbA1c and fasting plasma glucose

scientific article published on 28 March 2017

Glycation sites of human plasma proteins are affected to different extents by hyperglycemic conditions in type 2 diabetes mellitus

scientific article published on 30 July 2014

Glypican-4 enhances insulin signaling via interaction with the insulin receptor and serves as a novel adipokine

scientific article

Growth hormone induces apelin mRNA expression and secretion in mouse 3T3-L1 adipocytes

scientific article published on 28 November 2006

Growth hormone is a positive regulator of adiponectin receptor 2 in 3T3-L1 adipocytes

scientific article published on January 2004

Growth hormone replacement therapy regulates microRNA-29a and targets involved in insulin resistance

scientific article

HLA Class II Allele Analyses Implicate Common Genetic Components in Type 1 and Non-Insulin-Treated Type 2 Diabetes

scientific article published on 01 March 2020

Half-body MRI volumetry of abdominal adipose tissue in patients with obesity

scientific article published on 22 October 2019

Hedgehog signalling in myeloid cells impacts on body weight, adipose tissue inflammation and glucose metabolism

scientific article

Hepatic Rab24 controls blood glucose homeostasis via improving mitochondrial plasticity

scientific article published on 14 October 2019

Hepatocyte-secreted DPP4 in obesity promotes adipose inflammation and insulin resistance

scientific article published on 21 March 2018

Hepatocyte-specific activity of TSC22D4 triggers progressive NAFLD by impairing mitochondrial function

scientific article published on 01 April 2022

High baseline vitamin C levels do not prevent a positive outcome of a lifestyle intervention: response to Thamer et al.

scientific article published in January 2010

Higher HbA1c levels associate with lower hippocampal serotonin transporter availability in non-diabetic adults with obesity

scientific article published on 07 December 2020

Higher Mast Cell Accumulation in Human Adipose Tissues Defines Clinically Favorable Obesity Sub-Phenotypes

scientific article published on 20 June 2020

Hormonal regulation of the novel adipocytokine visfatin in 3T3-L1 adipocytes

scientific article published on June 2005

Hypermethylation of the non-imprinted maternal MEG3 and paternal MEST alleles is highly variable among normal individuals

scientific article published on 30 August 2017

Hypoxia-inducible factor 3A gene expression and methylation in adipose tissue is related to adipose tissue dysfunction

scientific article published on 27 June 2016

IRS1 DNA promoter methylation and expression in human adipose tissue are related to fat distribution and metabolic traits

scientific article published on 28 September 2017

Identification of a novel leptin receptor (LEPR) variant and proof of functional relevance directing treatment decisions in patients with morbid obesity

scientific article published on 19 November 2020

Identification of a regulatory pathway inhibiting adipogenesis via RSPO2

scientific article published on 13 January 2022

Identification of adipokine clusters related to parameters of fat mass, insulin sensitivity and inflammation

scientific article

Identification of distinct transcriptome signatures of human adipose tissue from fifteen depots

scientific article published on 13 July 2020

Identification of genetic loci associated with different responses to high-fat diet-induced obesity in C57BL/6N and C57BL/6J substrains

scientific article published in April 2014

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

scientific article published on 12 September 2017

Impact of the Thr789Ala variant of the von Willebrand factor levels, on ristocetin co-factor and collagen binding capacity and its association with coronary heart disease in patients with diabetes mellitus type 2.

scientific article published in December 2005

Impaired thermogenesis and adipose tissue development in mice with fat-specific disruption of insulin and IGF-1 signalling

scientific article published on June 12, 2012

Implication of Progranulin and C1q/TNF-Related Protein-3 (CTRP3) on Inflammation and Atherosclerosis in Subjects with or without Metabolic Syndrome

scientific article published on February 7, 2013

Importance of estrogen receptors in adipose tissue function

scientific article published on 06 July 2013

Improvement of insulin sensitivity after adrenalectomy in patients with pheochromocytoma

scientific article published in August 2003

Improvement of insulin sensitivity after adrenalectomy in patients with pheochromocytoma.

scientific article published in October 2000

In Depth Quantitative Proteomic and Transcriptomic Characterization of Human Adipocyte Differentiation Using the SGBS Cell Line

scientific article published on 08 May 2020

In-Vitro-Generated Hypertrophic-Like Adipocytes Displaying PPARG Isoforms Unbalance Recapitulate Adipocyte Dysfunctions In Vivo

scientific article published on 21 May 2020

Increased Ifi202b/IFI16 expression stimulates adipogenesis in mice and humans.

scientific article published on 24 February 2018

Increased Release of Proinflammatory Proteins in Primary Human Adipocytes and Activation of the Inflammatory NFĸB, p38, and ERK Pathways upon Omentin Treatment

scientific article published on 06 April 2020

Increased autophagy in peripheral nerves may protect Wistar Ottawa Karlsburg W rats against neuropathy

scientific article

Increased circulating cell-free DNA in insulin resistance

scientific article published on 20 June 2018

Independent and opposite associations of serum levels of omentin-1 and adiponectin with increases of glycaemia and incident type 2 diabetes in an older population: KORA F4/FF4 study

scientific article published on 5 July 2017

Insulin administration acutely decreases vaspin serum concentrations in humans.

scientific article published on 2 March 2013

Insulin resistance-inducing cytokines differentially regulate SOCS mRNA expression via growth factor- and Jak/Stat-signaling pathways in 3T3-L1 adipocytes

scientific article published on April 2004

Insulin up-regulates natriuretic peptide clearance receptor expression in the subcutaneous fat depot in obese subjects: a missing link between CVD risk and obesity?

scientific article published on 14 March 2012

Insulin-Like Peptide 5 Interacts with Sex Hormones and Metabolic Parameters in a Gender and Adiposity Dependent Manner in Humans

scientific article published on 29 June 2016

Insulin-sensitive obesity

scientific article published on 22 June 2010

Integrated Network Analysis Reveals an Association between Plasma Mannose Levels and Insulin Resistance

scientific article published on 21 June 2016

Interleukin-15 and irisin serum concentrations are not related to cardiometabolic risk factors in patients with type 2 diabetes from Korea and Germany

scientific article published on 10 September 2019

Interleukin-1beta induces the novel adipokine chemerin in adipocytes in vitro

scientific article published on 20 February 2009

Interleukin-1beta is a positive regulator of TIARP/STAMP2 gene and protein expression in adipocytes in vitro

scientific article

Interleukin-6 is a negative regulator of visfatin gene expression in 3T3-L1 adipocytes

scientific article published on 17 May 2005

Interleukin-6 is a positive regulator of tumor necrosis factor alpha-induced adipose-related protein in 3T3-L1 adipocytes

scientific journal article

Intermuscular adipose tissue and thigh muscle area dynamics during an 18-month randomized weight loss trial

scientific article

Interplay between Obesity-Induced Inflammation and cGMP Signaling in White Adipose Tissue

scientific article

Intrahepatic fat, abdominal adipose tissues, and metabolic state: magnetic resonance imaging study

scientific article published on 14 February 2017

Intramyocellular triacylglycerol accumulation across weight loss strategies; Sub-study of the CENTRAL trial

scientific article published on 30 November 2017

Intravenous Ferric Carboxymaltose in Patients with Type 2 Diabetes Mellitus and Iron Deficiency: CLEVER Trial Study Design and Protocol

scientific article published on 13 November 2017

Intrinsic heterogeneity in adipose tissue of fat-specific insulin receptor knock-out mice is associated with differences in patterns of gene expression

scientific article

Inverse relationship between obesity and FTO gene expression in visceral adipose tissue in humans

scientific article published on 5 February 2008

Isoproterenol stimulates monocyte chemoattractant protein-1 expression and secretion in 3T3-L1 adipocytes

scientific article published on 27 April 2006

Isoproterenol, TNFalpha, and insulin downregulate adipose triglyceride lipase in 3T3-L1 adipocytes

scientific article published on August 2005

Knowledge and practice regarding the German and the EASL-EASD-EASO NAFLD-guidelines among members of the German Obesity Society

scientific article published on 30 March 2018

Lack of association between peroxisome proliferator-activated receptor-gamma-2 gene variants and the occurrence of coronary heart disease in patients with diabetes mellitus

scientific article published in April 2002

Lack of association between the tagging SNP A+930-->G of SOCS3 and type 2 diabetes mellitus: meta-analysis of four independent study populations

scientific article

Lack of significant effects of the type 2 diabetes susceptibility loci JAZF1, CDC123/CAMK1D, NOTCH2, ADAMTS9, THADA, and TSPAN8/LGR5 on diabetes and quantitative metabolic traits

scientific article published on 10 August 2009

Leptin Within the Subphysiological to Physiological Range Dose Dependently Improves Male Reproductive Function in an Obesity Mouse Model

scientific article

Leptin stimulates autophagy/lysosome-related degradation of long-lived proteins in adipocytes

scientific article published on 08 February 2019

Leptin-deficient (ob/ob) mouse ovaries show fatty degeneration, enhanced apoptosis and decreased expression of steroidogenic acute regulatory enzyme

scientific article published on November 15, 2011

Leucocytes are a major source of circulating nicotinamide phosphoribosyltransferase (NAMPT)/pre-B cell colony (PBEF)/visfatin linking obesity and inflammation in humans

scientific article

Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms

scientific article published on January 2014

Linagliptin Improves Insulin Sensitivity and Hepatic Steatosis in Diet-Induced Obesity

scientific article published on June 22, 2012

LincRNA H19 protects from dietary obesity by constraining expression of monoallelic genes in brown fat

scientific article published in Nature Communications

Lipocalin-2 is induced by interleukin-1beta in murine adipocytes in vitro

scientific article published on January 2009

Liver ASK1 protects from non-alcoholic fatty liver disease and fibrosis

scientific article published on 06 June 2019

Liver-restricted Repin1 deficiency improves whole-body insulin sensitivity, alters lipid metabolism, and causes secondary changes in adipose tissue in mice.

scientific article

Local proliferation of macrophages in adipose tissue during obesity-induced inflammation

scientific article published on 17 December 2013

Long- but not short-term multifactorial intervention with focus on exercise training improves coronary endothelial dysfunction in diabetes mellitus type 2 and coronary artery disease

scientific article published on 30 September 2009

Long-term Relapse of Type 2 Diabetes After Roux-en-Y Gastric Bypass: Prediction and Clinical Relevance

scientific article published on 06 August 2018

Long-term exercise training decreases interleukin-6 (IL-6) serum levels in subjects with impaired glucose tolerance: effect of the -174G/C variant in IL-6 gene

scientific article published on 9 May 2008

Loss of function of Ifi202b by a microdeletion on chromosome 1 of C57BL/6J mice suppresses 11β-hydroxysteroid dehydrogenase type 1 expression and development of obesity

scientific article published on 12 June 2012

Loss of periostin occurs in aging adipose tissue of mice and its genetic ablation impairs adipose tissue lipid metabolism

Low vs. higher-dose dark chocolate and blood pressure in cardiovascular high-risk patients

scientific article published on 4 March 2010

Macrophage infiltration into omental versus subcutaneous fat across different populations: effect of regional adiposity and the comorbidities of obesity

scientific article published on 20 March 2007

Management of nicotinamide N-methyltransferase overexpression: inhibit the enzyme or reduce nicotinamide intake? Reply to Zhou S, Li D, Zhou Y [letter].

scientific article

Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers

scientific article

Mesenteric Fat Lipolysis Mediates Obesity-Associated Hepatic Steatosis and Insulin Resistance

scientific article published on 17 September 2015

Metabolic Syndrome: An Interdisciplinary Approach

scientific article published on 21 October 2016

Metabolic and genetic predictors of circulating adipocyte fatty acid-binding protein

scientific article published on August 23, 2011

Metabolic effects of genetic variation in the human REPIN1 gene

scientific article published on 18 June 2018

Metabolic profile and nitric oxide synthase expression of skeletal muscle fibers are altered in patients with type 1 diabetes

scientific article published on 9 May 2008

MicroRNA expression in human omental and subcutaneous adipose tissue

scientific article

Mitochondrial gene expression and increased oxidative metabolism: role in increased lifespan of fat-specific insulin receptor knock-out mice

scientific article

Mitogen-activated protein kinases, inhibitory-kappaB kinase, and insulin signaling in human omental versus subcutaneous adipose tissue in obesity

scientific article published on 22 February 2007

Molecular Characteristics of Serum Visfatin and Differential Detection by Immunoassays

Monocyte chemoattractant protein 1 expression is stimulated by growth hormone and interleukin-6 in 3T3-L1 adipocytes

scientific article published on April 2004

Multinucleated Giant Cells in Adipose Tissue are Specialized in Adipocyte Degradation

scientific article published on 06 November 2020

Mutational analysis of the gene encoding the zymogen granule membrane glycoprotein 2 (GP2) in patients with chronic pancreatitis

scientific article

Myeloid cell-restricted insulin receptor deficiency protects against obesity-induced inflammation and systemic insulin resistance

scientific article (publication date: May 2010)

NPY1R-targeted peptide-mediated delivery of a dual PPARα/γ agonist to adipocytes enhances adipogenesis and prevents diabetes progression

scientific article published on 16 November 2019

Neuregulin 4: A "Hotline" Between Brown Fat and Liver

scientific article published on 03 September 2019

Neurohumoral stimulation in type-2-diabetes as an emerging disease concept

scientific article

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

scientific article published on February 2016

Nicotinamide Nucleotide Transhydrogenase (Nnt) is Related to Obesity in Mice

scientific article published on 06 July 2020

Nicotinamide nucleotide transhydrogenase mRNA expression is related to human obesity

scientific article published in March 2013

Nitric oxide synthase in skeletal muscle fibers of patients with type 2 diabetes

scientific article published on 08 November 2012

Noradrenaline transporter availability on [11C]MRB PET predicts weight loss success in highly obese adults

scientific article published on 7 April 2018

Novel Function of Serine Protease HTRA1 in Inhibiting Adipogenic Differentiation of Human Mesenchymal Stem Cells via MAP Kinase-Mediated MMP Upregulation

scientific article

Novel genes on rat chromosome 10 are linked to body fat mass, preadipocyte number and adipocyte size

scientific article published on 27 July 2016

Obesity and Diabetes

scientific article published on 22 December 2020

Obesity and inflammation

scientific article published on 22 January 2013

Obesity and suicide risk in adults--a systematic review

scientific article published on 04 August 2012

Obesity-Induced Increase in Cystatin C Alleviates Tissue Inflammation

scientific article published on 02 July 2020

Obesity-induced CerS6-dependent C16:0 ceramide production promotes weight gain and glucose intolerance

scientific article published in October 2014

Obesity: The myth of innocent obesity

scientific article published in November 2017

Obesogenic memory can confer long-term increases in adipose tissue but not liver inflammation and insulin resistance after weight loss

scientific article published on 11 January 2016

PACAP up-regulates the expression of apolipoprotein D in 3T3-L1 adipocytes. DRG/3T3-L1 co-cultures study

scientific article published on November 13, 2010

PPARγΔ5, a Naturally Occurring Dominant-Negative Splice Isoform, Impairs PPARγ Function and Adipocyte Differentiation

scientific article published on 01 November 2018

PPP2R5C Couples Hepatic Glucose and Lipid Homeostasis

scientific article (publication date: October 2015)

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Palmitate induced IL-6 and MCP-1 expression in human bladder smooth muscle cells provides a link between diabetes and urinary tract infections

scientific article

Percutaneous intragastric catheter (PIC) for administration of an unpalatable substance to large animals

scientific article published in March 2009

Phenotype-tissue expression and exploration (PTEE) resource facilitates the choice of tissue for RNA-seq-based clinical genetics studies

scientific article published on 07 November 2021

Phenotypic and genetic variation in leptin as determinants of weight regain

scientific article published on November 2, 2010

Physical exercise in overweight to obese individuals induces metabolic- and neurotrophic-related structural brain plasticity

scientific article published on July 2015

Pill Burden in Patients With Type 2 Diabetes in Germany: Subanalysis From the Prospective, Noninterventional PROVIL Study

scientific article

Plasma Mannose Levels Are Associated with Incident Type 2 Diabetes and Cardiovascular Disease

scientific article published in August 2017

Plasma Proteins Modified by Advanced Glycation End Products (AGEs) Reveal Site-specific Susceptibilities to Glycemic Control in Patients with Type 2 Diabetes

scientific article

Plasma levels of free fatty acids correlate with type 2 diabetes mellitus

scientific article published on 30 July 2018

Plasma levels of tumor necrosis factor-alpha, angiotensin II, growth hormone, and IGF-I are not elevated in insulin-resistant obese individuals with impaired glucose tolerance

scientific article

Plasma visfatin concentrations and fat depot-specific mRNA expression in humans

scientific article published in October 2005

Plasminogen activator inhibitor-1 expression and secretion are stimulated by growth hormone and interleukin-6 in 3T3-L1 adipocytes

scientific article

Positional cloning of zinc finger domain transcription factor Zfp69, a candidate gene for obesity-associated diabetes contributed by mouse locus Nidd/SJL

scientific article

Post-dexamethasone serum copeptin corresponds to HPA axis responsiveness in human obesity

scientific article published on 16 January 2017

Predictive accuracy of single- and multi-slice MRI for the estimation of total visceral adipose tissue in overweight to severely obese patients

scientific article published on 25 March 2015

Preliminary report: Serum levels of retinol-binding protein 4 in preeclampsia

scientific article published in March 2009

Preliminary report: circulating levels of the adipokine vaspin in gestational diabetes mellitus and preeclampsia

scientific article published on 31 December 2009

Prenatal notch1 receptor blockade by protein delta homolog 1 (DLK1) modulates adipocyte size in vivo

scientific article published on 26 October 2015

Preoperative Upper-GI Endoscopy Prior to Bariatric Surgery: Essential or Optional?

scientific article published on 24 February 2020

Pro-Neurotensin depends on renal function and is related to all-cause mortality in chronic kidney disease

scientific article published on 01 June 2020

Pro-inflammatory macrophages increase in skeletal muscle of high fat-fed mice and correlate with metabolic risk markers in humans

scientific article published on 16 October 2013

Proinflammatory adipocytokines induce TIMP-1 expression in 3T3-L1 adipocytes

scientific article published on 2 November 2005

Protein kinase MST3 modulates lipid homeostasis in hepatocytes and correlates with nonalcoholic steatohepatitis in humans

scientific article published on 07 June 2019

Protein kinase STK25 controls lipid partitioning in hepatocytes and correlates with liver fat content in humans

scientific article published on 9 November 2015

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 22 December 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Psychometric properties of the Patient Assessment of Chronic Illness Care measure (PACIC-5A) among patients with obesity

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 16 March 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 01 July 2019

Quantitative Measurement of Full-Length and C-Terminal Proteolyzed RBP4 in Serum of Normal and Insulin-Resistant Humans using a Novel Mass Spectrometry Immunoassay

scientific article published on January 17, 2012

R1467H variant in the rho guanine nucleotide exchange factor 11 (ARHGEF11) is associated with impaired glucose tolerance and type 2 diabetes in German Caucasians

scientific article published on 31 January 2008

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Reduced food intake and body weight in mice deficient for the G protein-coupled receptor GPR82

scientific article (publication date: 2011)

Reduced lipolysis in lipoma phenocopies lipid accumulation in obesity

scientific article published on 24 November 2020

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

scientific article published on 9 April 2018

Regenerative capacity differs between micro- and macrovesicular hepatic steatosis

scientific article published on 14 September 2007

Regulation of adiponectin receptor R1 and R2 gene expression in adipocytes of C57BL/6 mice

scientific article published in April 2005

Regulation of the novel adipokines/ hepatokines fetuin A and fetuin B in gestational diabetes mellitus

scientific article published on 9 December 2016

Relation between glycaemic control, hyperinsulinaemia and plasma concentrations of soluble adhesion molecules in patients with impaired glucose tolerance or Type II diabetes

scientific article

Relationship between twelve adipocytokines and distinct components of the metabolic syndrome

scientific article published on 9 January 2018

Renal function following three distinct weight loss dietary strategies during 2 years of a randomized controlled trial

scientific article published on 20 May 2013

Repin1 deficiency improves insulin sensitivity and glucose metabolism in db/db mice by reducing adipose tissue mass and inflammation

scientific article published on 8 July 2016

Repin1 deficiency in adipose tissue improves whole-body insulin sensitivity, and lipid metabolism

scientific article published on 24 July 2017

Repin1 maybe involved in the regulation of cell size and glucose transport in adipocytes

scientific journal article

Retinol binding protein 4 (RBP4) is primarily associated with adipose tissue mass in children

scientific article published on 15 October 2010

Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects

scientific article

Retinol-binding protein 4 and new adipocytokines in nonalcoholic fatty liver disease

scientific article published on June 2010

Role of genetic variation in the cannabinoid type 1 receptor gene (CNR1) in the pathophysiology of human obesity

scientific article published in May 2010

Role of insulin action and cell size on protein expression patterns in adipocytes

scientific article

Role of the DNA repair genes H2AX and HMGB1 in human fat distribution and lipid profiles

scientific article published on 01 February 2020

Role of the Neutral Amino Acid Transporter Slc7a10 in Adipocyte Lipid Storage, Obesity and Insulin Resistance

scientific article published on 06 January 2021

Role of vaspin in human eating behaviour

scientific article

Routine fluoroscopic investigations after primary bariatric surgery

scientific article published on 7 August 2015

SORLA facilitates insulin receptor signaling in adipocytes and exacerbates obesity

scientific article published on 20 June 2016

STK25 is a critical determinant in nonalcoholic steatohepatitis

scientific article published on 15 July 2016

Secretory products from human adipocytes impair endothelial function via nuclear factor kappaB

scientific article published on 02 July 2007

Secretory products from human adipocytes stimulate proinflammatory cytokine secretion from human endothelial cells

scientific article published on 01 March 2009

Sequence analysis of the human tyrosylprotein sulfotransferase-2 gene in subjects with chronic pancreatitis

scientific article

Serine/threonine protein kinase 25 (STK25): a novel negative regulator of lipid and glucose metabolism in rodent and human skeletal muscle

scientific article published on March 4, 2012

Serum Levels of Adipocyte Fatty Acid–Binding Protein Are Decreased in Chronic Pancreatitis

scientific article published on November 1, 2012

Serum Levels of Copeptin are Decreased in Gestational Diabetes Mellitus

scientific article published on 29 January 2016

Serum Levels of the Adipokine Fasting-induced Adipose Factor/Angiopoietin-like Protein 4 Depend on Renal Function

scientific article published on October 22, 2010

Serum adiponectin and progranulin levels are associated with gallstone disease

scientific article

Serum amyloid A3 expression is stimulated by dexamethasone and interleukin-6 in 3T3-L1 adipocytes

scientific article published on December 2004

Serum fibroblast growth factor 21 levels in gestational diabetes mellitus in relation to insulin resistance and dyslipidemia

scientific article published on 21 August 2009

Serum levels of adipocyte fatty acid binding protein are increased in gestational diabetes mellitus

scientific article

Serum levels of adipocyte fatty acid-binding protein (AFABP) are increased in chronic haemodialysis (CD).

scientific article

Serum levels of adipokine retinol-binding protein-4 in relation to renal function

scientific article published on 13 July 2007

Serum levels of angiopoietin-related growth factor are increased in preeclampsia

scientific article published on 4 December 2008

Serum levels of angiopoietin-related growth factor in diabetes mellitus and chronic hemodialysis

scientific article published in April 2009

Serum levels of fibroblast growth factor-21 are increased in chronic and acute renal dysfunction

scientific article published on 12 January 2014

Serum levels of fractalkine are associated with markers of insulin resistance in gestational diabetes

scientific article published on 16 April 2014

Serum levels of growth arrest specific protein 6 are increased in preeclampsia

scientific article

Serum levels of irisin in gestational diabetes mellitus during pregnancy and after delivery

scientific article published on 16 December 2013

Serum levels of the adipokine FGF21 depend on renal function

scientific article published on 07 October 2008

Serum levels of the adipokine adipocyte fatty acid-binding protein are increased in preeclampsia

scientific article published on 13 March 2008

Serum levels of the adipokine chemerin are increased in preeclampsia during and 6 months after pregnancy

scientific article published on April 12, 2011

Serum levels of the adipokine chemerin in relation to renal function

scientific article

Serum levels of the adipokine fibroblast growth factor-21 are increased in preeclampsia

scientific article

Serum levels of the adipokine lipocalin-2 are increased in preeclampsia

scientific article

Serum levels of the adipokine progranulin depend on renal function

scientific article published on October 2012

Serum levels of the adipokine vaspin in relation to metabolic and renal parameters

scientific article published on 23 October 2007

Serum levels of the adipokine visfatin are increased in pre-eclampsia

scientific article published in July 2008

Serum levels of the adipokine zinc-α2-glycoprotein are increased in chronic hemodialysis

scientific article published on 12 August 2010

Serum levels of the adipokine zinc-α2-glycoprotein are increased in preeclampsia

scientific article published on July 27, 2011

Serum levels of the atherosclerosis biomarker sTWEAK are decreased in type 2 diabetes and end-stage renal disease

scientific article published on 3 December 2007

Serum levels of the myokine irisin in relation to metabolic and renal function

scientific article

Serum progranulin concentrations may be associated with macrophage infiltration into omental adipose tissue

scientific article published on 03 December 2008

Serum retinol-binding protein is more highly expressed in visceral than in subcutaneous adipose tissue and is a marker of intra-abdominal fat mass

scientific article published on 01 July 2007

Serum vaspin concentrations are decreased after exercise-induced oxidative stress.

scientific article published on 20 October 2010

Serum vaspin concentrations in human obesity and type 2 diabetes

scientific article published on 8 November 2007

Sex differences in serotonin-hypothalamic connections underpin a diminished sense of emotional well-being with increasing body weight

scientific article published on 22 April 2016

Short-Term Changes of the Urine Metabolome After Bariatric Surgery

scientific article published on October 24, 2012

Short-term cold exposure supports human Treg induction in vivo

scientific article published on 05 August 2019

Shox2 is a molecular determinant of depot-specific adipocyte function

scientific article published on 24 June 2013

Site-specific analysis of advanced glycation end products in plasma proteins of type 2 diabetes mellitus patients

scientific article

Software for automated MRI‐based quantification of abdominal fat and preliminary evaluation in morbidly obese patients

scientific article published on November 2, 2012

Strategies for successful weight reduction - focus on energy balance

scientific article published on October 17, 2012

Surgical Treatment of Type 2 Diabetes

scientific article published on December 2016

T-lymphocyte infiltration in visceral adipose tissue: a primary event in adipose tissue inflammation and the development of obesity-mediated insulin resistance

scientific article published on 17 April 2008

TCF7L2 gene expression in human visceral and subcutaneous adipose tissue is differentially regulated but not associated with type 2 diabetes mellitus

scientific article

TSH compensates thyroid-specific IGF-I receptor knockout and causes papillary thyroid hyperplasia

scientific article

Tamoxifen affects glucose and lipid metabolism parameters, causes browning of subcutaneous adipose tissue and transient body composition changes in C57BL/6NTac mice

scientific article published on 8 July 2015

Tamoxifen treatment causes early hepatic insulin resistance

scientific article published on 06 January 2020

Tbx15 Defines a Glycolytic Subpopulation and White Adipocyte Heterogeneity

scientific article

Telomere length differences between subcutaneous and visceral adipose tissue in humans

scientific article published on 13 January 2015

The ARF-like GTPase ARFRP1 is essential for lipid droplet growth and is involved in the regulation of lipolysis

scientific article

The Choosing Wisely Initiative of the German Society of Internal Medicine : Recommendations of the German Society for Endocrinology and the German Society for Geriatrics

scientific article published on 27 May 2016

The Effect of Wolffia globosa Mankai, a Green Aquatic Plant, on Postprandial Glycemic Response: A Randomized Crossover Controlled Trial

scientific article published on 10 May 2019

The Fabp4-Cre-Model is Insufficient to Study Hoxc9 Function in Adipose Tissue

scientific article published on 29 June 2020

The Gq signalling pathway inhibits brown and beige adipose tissue

scientific article published on 9 March 2016

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

The Novel Adipokine Gremlin 1 Antagonizes Insulin Action and Is Increased in Type 2 Diabetes and NAFLD/NASH

scientific article published on 27 December 2019

The Obesity-Susceptibility Gene TMEM18 Promotes Adipogenesis through Activation of PPARG

scientific article published on 01 October 2020

The Promoter Variant -803 G>A in the RBP4 gene is not Associated with BMI, Metabolic Parameters or Blood Pressure in Caucasian Children

article

The Role of Iron and Nerve Inflammation in Diabetes Mellitus Type 2-Induced Peripheral Neuropathy

scientific article published on 10 March 2019

The SGLT2 inhibitor empagliflozin improves insulin sensitivity in db/db mice both as monotherapy and in combination with linagliptin

scientific article published on 13 November 2015

The adipokine SAA3 is induced by interleukin-1beta in mouse adipocytes

scientific article published on August 2008

The association between in vivo central noradrenaline transporter availability and trait impulsivity

scientific article

The beneficial effects of Mediterranean diet over low-fat diet may be mediated by decreasing hepatic fat content

scientific article published on 08 May 2019

The brown fat-enriched secreted factor Nrg4 preserves metabolic homeostasis through attenuation of hepatic lipogenesis

scientific article

The brown fat-secreted adipokine neuregulin 4 is decreased in human and murine chronic kidney disease

scientific article published on 01 August 2019

The brown-fat-secreted adipokine neuregulin 4 is decreased in gestational diabetes mellitus

scientific article

The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue

scientific article published on 27 March 2017

The distinction of metabolically 'healthy' from 'unhealthy' obese individuals

scientific article published on February 2010

The effect of green Mediterranean diet on cardiometabolic risk; a randomised controlled trial

scientific article published on 23 November 2020

The effect of long-term weight-loss intervention strategies on the dynamics of pancreatic-fat and morphology: An MRI RCT study

scientific article published on 6 February 2018

The effect of serum BDNF levels on central serotonin transporter availability in obese versus non-obese adults: A [(11)C]DASB positron emission tomography study

scientific article

The genetics of fat distribution

scientific article published on 16 March 2014

The inflammatory process of adipose tissue.

scientific article published on September 2008

The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance

scientific article

The novel adipokine/hepatokine fetuin B in severe human and murine diabetic kidney disease

scientific article published on 14 February 2017

The obesity-induced transcriptional regulator TRIP-Br2 mediates visceral fat endoplasmic reticulum stress-induced inflammation

scientific article (publication date: 25 April 2016)

The polygenetically inherited metabolic syndrome of WOKW rats is associated with insulin resistance and altered gene expression in adipose tissue

scientific article

The polygenetically inherited metabolic syndrome of male WOKW rats is associated with enhanced autophagy in adipose tissue

scientific article published on 13 May 2013

The role of dietary non-heme iron load and peripheral nerve inflammation in the development of peripheral neuropathy (PN) in obese non-diabetic leptin-deficient ob/ob mice

scientific article published on 13 January 2019

The role of nerve inflammation and exogenous iron load in experimental peripheral diabetic neuropathy (PDN).

scientific article published on 6 November 2015

Therapeutic perspectives of adipocytokines

scientific article

Thyroid hormone status defines brown adipose tissue activity and browning of white adipose tissues in mice

scientific article published on 12 December 2016

Tissue inhibitor of metalloproteinase 1 expression and secretion are induced by beta-adrenergic stimulation in 3T3-L1 adipocytes

scientific article published on June 2006

Tissue inhibitor of metalloproteinase-1 mRNA production and protein secretion are induced by interleukin-1 beta in 3T3-L1 adipocytes

scientific article

Tissue inhibitor of metalloproteinase-1 predicts adiposity in humans

scientific article published in February 2007

Total and high-molecular weight adiponectin in relation to metabolic variables at baseline and in response to an exercise treatment program: comparative evaluation of three assays

scientific article published in February 2007

Transgenic animal models for the study of adipose tissue biology

scientific article

Tributyltin affects adipogenic cell fate commitment in mesenchymal stem cells by a PPARγ independent mechanism

scientific article

Two patterns of adipokine and other biomarker dynamics in a long-term weight loss intervention

scientific article published on 21 December 2011

Understanding the barriers and improving care in type 2 diabetes: Brazilian perspective in time to do more in diabetes

scientific article

Up-regulated autophagy: as a protective factor in adipose tissue of WOKW rats with metabolic syndrome.

scientific article

Variants in CPA1 are strongly associated with early onset chronic pancreatitis

scientific article published on 18 August 2013

Vaspin gene expression in human adipose tissue: association with obesity and type 2 diabetes

scientific article

Vaspin in obesity and diabetes: pathophysiological and clinical significance

scientific article published on 03 December 2011

Vaspin inhibits kallikrein 7 by serpin mechanism

scientific article

Vaspin is related to gender, puberty and deteriorating insulin sensitivity in children

Vaspin serum concentrations in patients with carotid stenosis

scientific article published on 2 September 2008

Vaspin suppresses cytokine-induced inflammation in 3T3-L1 adipocytes via inhibition of NFκB pathway

scientific article published on 26 July 2017

Vaspin--a link of obesity and psoriasis?

scientific article published on 01 April 2012

Visceral adipose tissue and metabolic syndrome

scientific article published on October 31, 2003

Visfatin is a positive regulator of MCP-1 in human adipocytes in vitro and in mice in vivo

scientific article published on 24 December 2009

Visfatin/PBEF/Nampt: structure, regulation and potential function of a novel adipokine

scientific article published on July 2008

WISP1 is a novel adipokine linked to inflammation in obesity

scientific article published on 3 October 2014

Weight loss with a low-carbohydrate, Mediterranean, or low-fat diet

scientific article

[Metabolic syndrome -- myths, mechanisms, management]

scientific article published on 01 May 2006

[Role of muscle and fat tissue in the pathogenesis of type 2 diabetes]

scientific article published on 01 December 2006

[The biology of visceral fat]

scientific article published on 01 February 2007

microRNA-379 couples glucocorticoid hormones to dysfunctional lipid homeostasis

scientific article

p50alpha/p55alpha phosphoinositide 3-kinase knockout mice exhibit enhanced insulin sensitivity

scientific article

p8 deficiency leads to elevated pancreatic beta cell mass but does not contribute to insulin resistance in mice fed with high-fat diet

scientific article published on 24 July 2018