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List of works by Jan Potempa

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Biochemical and structural characterization of SplD protease from Staphylococcus aureus

scientific article
The gingipains from Porphyromonas gingivalis do not directly induce osteoclast differentiation in primary mouse bone marrow cultures.

scientific article
The staphostatin family of cysteine protease inhibitors in the genus Staphylococcus as an example of parallel evolution of protease and inhibitor specificity

scientific article published in February 2007
Structural insights unravel the zymogenic mechanism of the virulence factor gingipain K from Porphyromonas gingivalis, a causative agent of gum disease from the human oral microbiome

scientific article
Inactive Gingipains from P. gingivalis Selectively Skews T Cells toward a Th17 Phenotype in an IL-6 Dependent Manner

scientific article
The fluorescence quenching resolved spectra and red-edge excitation fluorescence measurements of human alpha 1-proteinase inhibitor

scientific article published on 01 April 1991
Benzamidine derivatives inhibit the virulence of Porphyromonas gingivalis

scientific article published on 26 December 2012
Stimulation of proteinase and amidase activities in Porphyromonas (Bacteroides) gingivalis by amino acids and dipeptides

scientific article published on August 1991
Adhesive protein-mediated cross-talk between Candida albicans and Porphyromonas gingivalis in dual species biofilm protects the anaerobic bacterium in unfavorable oxic environment

scientific article published on 13 March 2019
Comparison of pathogenic properties between two types of arginine-specific cysteine proteinases (gingipains-R) from Porphyromonas gingivalis

scientific article published on 01 September 2000
Zebrafish as a new model to study effects of periodontal pathogens on cardiovascular diseases.

scientific article published on 25 October 2016
A phage display selected 7-mer peptide inhibitor of the Tannerella forsythia metalloprotease-like enzyme Karilysin can be truncated to Ser-Trp-Phe-Pro

scientific article
Selective inhibition of Porphyromonas gingivalis growth by a factor Xa inhibitor, DX-9065a

scientific article published on 01 June 2006
Development and binding characteristics of phosphonate inhibitors of SplA protease from Staphylococcus aureus

scientific article
Impact of Porphyromonas gingivalis Peptidylarginine Deiminase on Bacterial Biofilm Formation, Epithelial Cell Invasion, and Epithelial Cell Transcriptional Landscape

scientific article published on 20 September 2018
Structure of RagB, a major immunodominant outer-membrane surface receptor antigen of Porphyromonas gingivalis

scientific article
Crystallization and preliminary X‐ray diffraction analysis of gingipain R2 from Porphyromonas gingivalis in complex with H‐D‐Phe‐Phe‐Arg‐chloromethylketone

scientific article published on May 1, 1998
Porphyromonas gingivalis enzymes enhance infection with human metapneumovirus in vitro

scientific article published on 29 June 2011
Gingipains of Porphyromonas gingivalis Affect the Stability and Function of Serine Protease Inhibitor of Kazal-type 6 (SPINK6), a Tissue Inhibitor of Human Kallikreins

scientific article published on 27 June 2016
Elastinolytic activity of horse leukocyte proteinases. Comparison with elastases from human leukocytes and porcine pancreas

scientific article published in January 1986
Effect of serine proteinase from Staphylococcus aureus on in vitro stimulation of human lymphocytes

scientific article published on 01 October 1988
A Unique Mdm2-Binding Mode of the 3-Pyrrolin-2-one- and 2-Furanone-Based Antagonists of the p53-Mdm2 Interaction

scientific article
Aristolochic acid I determine the phenotype and activation of macrophages in acute and chronic kidney disease

scientific article published in Scientific Reports
Equine leukocyte elastase inhibitor. Primary structure and identification as a thymosin-binding protein

scientific article
The intrinsic enzymatic activity of procarboxypeptidase U (TAFI) does not significantly influence the fibrinolytic rate: reply to a rebuttal

scientific article published on 01 June 2007
Comparison of antiproteolytic activities of alpha-1-proteinase inhibitors from the plasma of some mammalian species

scientific article published on 01 January 1986
Attenuated kinin release from human neutrophil elastase-pretreated kininogens by tissue and plasma kallikreins

scientific article
Structural and functional characterization of elastases from horse neutrophils

scientific article published on June 1994
Organ-preserving surgical therapy of the transverse rupture of the kidney

scientific article published on 01 November 1967
Chemoattractant activity of Staphylococcus aureus serine proteinase modified human plasma alpha-1-proteinase inhibitor

scientific article published on 01 November 1989
Role of OmpA2 surface regions of Porphyromonas gingivalis in host-pathogen interactions with oral epithelial cells.

scientific article
Antimicrobial and Attractant Roles for Chemerin in the Oral Cavity during Inflammatory Gum Disease

scientific article published on 29 March 2017
Gingival Fibromatosis with Significant De Novo Formation of Fibrotic Tissue and a High Rate of Recurrence.

scientific article
A structure-derived snap-trap mechanism of a multispecific serpin from the dysbiotic human oral microbiome

scientific article
Structure, function, and inhibition of a genomic/clinical variant of Porphyromonas gingivalis peptidylarginine deiminase

scientific article published on 30 January 2019
Indications for conservative and operative treatment of closed kidney injuries

scientific article
Stability of infectious human coronavirus NL63.

scientific article published on 18 April 2014
Inhibition of tumor necrosis factor-alpha-induced RANTES secretion by alkaline protease in A549 cells

scientific article published on 21 July 2005
Gingipain K

article
Vaccination with recombinant RgpA peptide protects against Porphyromonas gingivalis-induced bone loss

scientific article published on 10 June 2016
TIMP-1 association with collagen type I overproduction in hereditary gingival fibromatosis

scientific article published on 14 August 2018
Staphylococcal SplB Serine Protease Utilizes a Novel Molecular Mechanism of Activation

scientific article
Antithrombin III activity in horses with colic: an analysis of 46 cases.

scientific article
Relationship between past myocardial infarction, periodontal disease and Porphyromonas gingivalis serum antibodies: A case-control study

scientific article
In vivo expression of proteases and protease inhibitor, a serpin, by periodontal pathogens at teeth and implants

scientific article published on 17 April 2018
Effect of dexamethasone on alpha 1-proteinase inhibitor synthesis in human cells of monocytic origin

scientific article published on March 1995
Horse leucocyte proteinase-inhibitor system. Kinetic parameters of the inhibition reaction

scientific article published on 01 January 1985
Oncostatin M stimulates the expression and release of the IL-6 receptor in human hepatoma HepG2 cells

Triggering NETosis via protease-activated receptor (PAR)-2 signaling as a mechanism of hijacking neutrophils function for pathogen benefits

scientific article published on 20 May 2019
Exploring the Sn binding pockets in gingipains by newly developed inhibitors: structure-based design, chemistry, and activity

scientific article published in March 2006

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