List of works - Jan Potempa

Induction of vascular leakage through release of bradykinin and a novel kinin by cysteine proteinases from Staphylococcus aureus

scientific article

Binding of complement inhibitor C4b-binding protein contributes to serum resistance of Porphyromonas gingivalis

scientific article published on October 2008

Degradation of host heme proteins by lysine- and arginine-specific cysteine proteinases (gingipains) of Porphyromonas gingivalis.

scientific article

Modulation of interleukin-8 activity by gingipains from Porphyromonas gingivalis: implications for pathogenicity of periodontal disease

scientific article published on 01 December 1998

Comparison of gingival crevicular fluid sampling methods in patients with severe chronic periodontitis.

scientific article

A novel mechanism for bradykinin production at inflammatory sites. Diverse effects of a mixture of neutrophil elastase and mast cell tryptase versus tissue and plasma kallikreins on native and oxidized kininogens

scientific article published in December 1998

The 1.8 A crystal structure of human cathepsin G in complex with Suc-Val-Pro-PheP-(OPh)2: a Janus-faced proteinase with two opposite specificities

scientific article

The case for periodontitis in the pathogenesis of rheumatoid arthritis

scientific article published on 24 August 2017

Presence of Porphyromonas gingivalis in esophagus and its association with the clinicopathological characteristics and survival in patients with esophageal cancer

scientific article

Interaction of regulators Mdm2 and Mdmx with transcription factors p53, p63 and p73.

scientific article published on 15 November 2010

NsaRS is a cell-envelope-stress-sensing two-component system of Staphylococcus aureus

scientific article

Porphyromonas gingivalis HmuY and HmuR: further characterization of a novel mechanism of heme utilization

scientific article published on 06 October 2007

Complementary Tolls in the periodontium: how periodontal bacteria modify complement and Toll-like receptor responses to prevail in the host

scientific article published on February 2010

Identification and characterization of sigma, a novel component of the Staphylococcus aureus stress and virulence responses

scientific article

Porphyromonas gingivalis induce apoptosis in human gingival epithelial cells through a gingipain-dependent mechanism

scientific article

Staphylococcal proteases aid in evasion of the human complement system

scientific article

Prolyl tripeptidyl peptidase from Porphyromonas gingivalis. A novel enzyme with possible pathological implications for the development of periodontitis

scientific article

A novel matrix metalloprotease-like enzyme (karilysin) of the periodontal pathogen Tannerella forsythia ATCC 43037

scientific article

Unique Structure and Stability of HmuY, a Novel Heme-Binding Protein of Porphyromonas gingivalis

scientific article

Gingipains from Porphyromonas gingivalis synergistically induce the production of proinflammatory cytokines through protease-activated receptors with Toll-like receptor and NOD1/2 ligands in human monocytic cells

scientific article published on 7 January 2008

Crystal structure of cleaved equine leucocyte elastase inhibitor determined at 1·95Å resolution

scientific article published on August 20, 1992

Sequential autolytic processing activates the zymogen of Arg-gingipain

scientific article published on 17 January 2003

Genetic Variation of Porphyromonas gingivalis Genes Encoding Gingipains, Cysteine Proteinases with Arginine or Lysine Specificity

scientific article published on February 1, 1998

Bacterial and human peptidylarginine deiminases: targets for inhibiting the autoimmune response in rheumatoid arthritis?

scientific article

Regulation of chemerin chemoattractant and antibacterial activity by human cysteine cathepsins

scientific article published on 29 June 2011

Optimal time for treating cryptorchism (author's transl)

scientific article published on March 28, 1975

Gingipains from Porphyromonas gingivalis W83 synergistically disrupt endothelial cell adhesion and can induce caspase-independent apoptosis

scientific article

Site-specific O-glycosylation on the MUC2 mucin protein inhibits cleavage by the Porphyromonas gingivalis secreted cysteine protease (RgpB).

scientific article published on April 2013

Purification and characterization of a novel endopeptidase in ragweed (Ambrosia artemisiifolia) pollen

scientific article published on October 1996

Staphostatins: an expanding new group of proteinase inhibitors with a unique specificity for the regulation of staphopains, Staphylococcus spp. cysteine proteinases

scientific article

Antibodies to Porphyromonas gingivalis Indicate Interaction Between Oral Infection, Smoking, and Risk Genes in Rheumatoid Arthritis Etiology.

scientific article published on 10 November 2015

Staphylococcus aureus-derived staphopain B, a potent cysteine protease activator of plasma chemerin

scientific article published in March 2007

Degradation of elastin by a cysteine proteinase from Staphylococcus aureus.

scientific article published on 01 February 1988

Rapid and efficient inactivation of IL-6 gingipains, lysine- and arginine-specific proteinases from Porphyromonas gingivalis

scientific article published on 01 August 1999

Three-dimensional structure of MecI. Molecular basis for transcriptional regulation of staphylococcal methicillin resistance

scientific article

Purification and characterization of gingipains

scientific article published on August 2007

A new insight into phagocytosis of apoptotic cells: proteolytic enzymes divert the recognition and clearance of polymorphonuclear leukocytes by macrophages

scientific article

Kinin danger signals proteolytically released by gingipain induce Fimbriae-specific IFN-gamma- and IL-17-producing T cells in mice infected intramucosally with Porphyromonas gingivalis.

scientific article published on 17 August 2009

Dependence of vascular permeability enhancement on cysteine proteinases in vesicles of Porphyromonas gingivalis

scientific article

Activation of blood coagulation factor X by arginine-specific cysteine proteinases (gingipain-Rs) from Porphyromonas gingivalis

scientific article published on 01 June 1997

Amino-acid sequence and three-dimensional structure of the Staphylococcus aureus metalloproteinase at 1.72 A resolution

scientific article

Investigations into sigmaB-modulated regulatory pathways governing extracellular virulence determinant production in Staphylococcus aureus

scientific article

Inactivation of membrane tumor necrosis factor alpha by gingipains from Porphyromonas gingivalis

scientific article

On the transcriptional regulation of methicillin resistance: MecI repressor in complex with its operator

scientific article

HmuY haemophore and gingipain proteases constitute a unique syntrophic system of haem acquisition by Porphyromonas gingivalis

scientific article

Degradation of fibrinogen and collagen by staphopains, cysteine proteases released from Staphylococcus aureus

scientific article published on 16 November 2010

The S-layer proteins of Tannerella forsythia are secreted via a type IX secretion system that is decoupled from protein O-glycosylation.

scientific article

A new pathway of staphylococcal pathogenesis: apoptosis-like death induced by Staphopain B in human neutrophils and monocytes

scientific article published on 2 December 2008

The Type IX Secretion System (T9SS): Highlights and Recent Insights into Its Structure and Function.

scientific article

Staphylococcal cysteine protease staphopain B (SspB) induces rapid engulfment of human neutrophils and monocytes by macrophages

scientific article published in April 2009

List of works by Jan Potempa

Induction of vascular leakage through release of bradykinin and a novel kinin by cysteine proteinases from Staphylococcus aureus

Binding of complement inhibitor C4b-binding protein contributes to serum resistance of Porphyromonas gingivalis

Degradation of host heme proteins by lysine- and arginine-specific cysteine proteinases (gingipains) of Porphyromonas gingivalis.

Modulation of interleukin-8 activity by gingipains from Porphyromonas gingivalis: implications for pathogenicity of periodontal disease

Comparison of gingival crevicular fluid sampling methods in patients with severe chronic periodontitis.

A novel mechanism for bradykinin production at inflammatory sites. Diverse effects of a mixture of neutrophil elastase and mast cell tryptase versus tissue and plasma kallikreins on native and oxidized kininogens

The 1.8 A crystal structure of human cathepsin G in complex with Suc-Val-Pro-PheP-(OPh)2: a Janus-faced proteinase with two opposite specificities

The case for periodontitis in the pathogenesis of rheumatoid arthritis

Presence of Porphyromonas gingivalis in esophagus and its association with the clinicopathological characteristics and survival in patients with esophageal cancer

Interaction of regulators Mdm2 and Mdmx with transcription factors p53, p63 and p73.

NsaRS is a cell-envelope-stress-sensing two-component system of Staphylococcus aureus

Porphyromonas gingivalis HmuY and HmuR: further characterization of a novel mechanism of heme utilization

Complementary Tolls in the periodontium: how periodontal bacteria modify complement and Toll-like receptor responses to prevail in the host

Identification and characterization of sigma, a novel component of the Staphylococcus aureus stress and virulence responses

Porphyromonas gingivalis induce apoptosis in human gingival epithelial cells through a gingipain-dependent mechanism

Staphylococcal proteases aid in evasion of the human complement system

Prolyl tripeptidyl peptidase from Porphyromonas gingivalis. A novel enzyme with possible pathological implications for the development of periodontitis

A novel matrix metalloprotease-like enzyme (karilysin) of the periodontal pathogen Tannerella forsythia ATCC 43037

Unique Structure and Stability of HmuY, a Novel Heme-Binding Protein of Porphyromonas gingivalis

Gingipains from Porphyromonas gingivalis synergistically induce the production of proinflammatory cytokines through protease-activated receptors with Toll-like receptor and NOD1/2 ligands in human monocytic cells

Crystal structure of cleaved equine leucocyte elastase inhibitor determined at 1·95Å resolution

Sequential autolytic processing activates the zymogen of Arg-gingipain

Genetic Variation of Porphyromonas gingivalis Genes Encoding Gingipains, Cysteine Proteinases with Arginine or Lysine Specificity

Bacterial and human peptidylarginine deiminases: targets for inhibiting the autoimmune response in rheumatoid arthritis?

Regulation of chemerin chemoattractant and antibacterial activity by human cysteine cathepsins

Optimal time for treating cryptorchism (author's transl)

Gingipains from Porphyromonas gingivalis W83 synergistically disrupt endothelial cell adhesion and can induce caspase-independent apoptosis

Site-specific O-glycosylation on the MUC2 mucin protein inhibits cleavage by the Porphyromonas gingivalis secreted cysteine protease (RgpB).

Purification and characterization of a novel endopeptidase in ragweed (Ambrosia artemisiifolia) pollen

Staphostatins: an expanding new group of proteinase inhibitors with a unique specificity for the regulation of staphopains, Staphylococcus spp. cysteine proteinases

Antibodies to Porphyromonas gingivalis Indicate Interaction Between Oral Infection, Smoking, and Risk Genes in Rheumatoid Arthritis Etiology.

Staphylococcus aureus-derived staphopain B, a potent cysteine protease activator of plasma chemerin

Degradation of elastin by a cysteine proteinase from Staphylococcus aureus.

Rapid and efficient inactivation of IL-6 gingipains, lysine- and arginine-specific proteinases from Porphyromonas gingivalis

Three-dimensional structure of MecI. Molecular basis for transcriptional regulation of staphylococcal methicillin resistance

Purification and characterization of gingipains

A new insight into phagocytosis of apoptotic cells: proteolytic enzymes divert the recognition and clearance of polymorphonuclear leukocytes by macrophages

Kinin danger signals proteolytically released by gingipain induce Fimbriae-specific IFN-gamma- and IL-17-producing T cells in mice infected intramucosally with Porphyromonas gingivalis.

Dependence of vascular permeability enhancement on cysteine proteinases in vesicles of Porphyromonas gingivalis

Activation of blood coagulation factor X by arginine-specific cysteine proteinases (gingipain-Rs) from Porphyromonas gingivalis

Amino-acid sequence and three-dimensional structure of the Staphylococcus aureus metalloproteinase at 1.72 A resolution

Investigations into sigmaB-modulated regulatory pathways governing extracellular virulence determinant production in Staphylococcus aureus

Inactivation of membrane tumor necrosis factor alpha by gingipains from Porphyromonas gingivalis

On the transcriptional regulation of methicillin resistance: MecI repressor in complex with its operator

HmuY haemophore and gingipain proteases constitute a unique syntrophic system of haem acquisition by Porphyromonas gingivalis

Degradation of fibrinogen and collagen by staphopains, cysteine proteases released from Staphylococcus aureus

The S-layer proteins of Tannerella forsythia are secreted via a type IX secretion system that is decoupled from protein O-glycosylation.

A new pathway of staphylococcal pathogenesis: apoptosis-like death induced by Staphopain B in human neutrophils and monocytes

The Type IX Secretion System (T9SS): Highlights and Recent Insights into Its Structure and Function.

Staphylococcal cysteine protease staphopain B (SspB) induces rapid engulfment of human neutrophils and monocytes by macrophages