Search filters

List of works by Jan Potempa

1H, 15N and 13C NMR resonance assignments of staphostatin A, a specific Staphylococcus aureus cysteine proteinase inhibitor

scientific article published in March 2004

A Dual Role for P2X7 Receptor during Porphyromonas gingivalis Infection

scientific article

A Metalloproteinase Mirolysin of Tannerella forsythia Inhibits All Pathways of the Complement System

scientific article

A New Autocatalytic Activation Mechanism for Cysteine Proteases Revealed by Prevotella intermedia Interpain A

scientific article

A Novel Biological Role for Peptidyl-Arginine Deiminases: Citrullination of Cathelicidin LL-37 Controls the Immunostimulatory Potential of Cell-Free DNA.

scientific article published on 23 February 2018

A Peptide Domain on Gingipain R Which Confers Immunity against Porphyromonas gingivalis Infection in Mice ⬇️

scientific article published on September 1, 1998

A Unique Mdm2-Binding Mode of the 3-Pyrrolin-2-one- and 2-Furanone-Based Antagonists of the p53-Mdm2 Interaction

scientific article

A comparison of staphostatin B with standard mechanism serine protease inhibitors

scientific article published on 11 January 2005

A metalloproteinase karilysin present in the majority of Tannerella forsythia isolates inhibits all pathways of the complement system

scientific article published on 27 January 2012

A natural anti-periodontitis agent, epimedokoreanin B, inhibits virulence activities of gingipains from Porphyromonas gingivalis

scientific article published on 26 March 2019

A new insight into phagocytosis of apoptotic cells: proteolytic enzymes divert the recognition and clearance of polymorphonuclear leukocytes by macrophages.

scientific article

A new pathway of staphylococcal pathogenesis: apoptosis-like death induced by Staphopain B in human neutrophils and monocytes

scientific article published on 2 December 2008

A novel class of cysteine protease inhibitors: solution structure of staphostatin A from Staphylococcus aureus

scientific article

A novel matrix metalloprotease-like enzyme (karilysin) of the periodontal pathogen Tannerella forsythia ATCC 43037

scientific article

A novel mechanism for bradykinin production at inflammatory sites. Diverse effects of a mixture of neutrophil elastase and mast cell tryptase versus tissue and plasma kallikreins on native and oxidized kininogens.

scientific article published in December 1998

A novel mechanism of latency in matrix metalloproteinases

scientific article published on 2 January 2015

A pathogenic trace of Tannerella forsythia - shedding of soluble fully active tumor necrosis factor α from the macrophage surface by karilysin

scientific article

A phage display selected 7-mer peptide inhibitor of the Tannerella forsythia metalloprotease-like enzyme Karilysin can be truncated to Ser-Trp-Phe-Pro ⬇️

scientific article

A potential new pathway for Staphylococcus aureus dissemination: the silent survival of S. aureus phagocytosed by human monocyte-derived macrophages

scientific article

A relationship between proteinase activity and clinical parameters in the treatment of periodontal disease ⬇️

scientific article published on July 1, 1998

A structure-derived snap-trap mechanism of a multispecific serpin from the dysbiotic human oral microbiome

scientific article

A unique bacterial secretion machinery with multiple secretion centers

scientific article published on 26 April 2022

Acquisition of complement inhibitor serine protease factor I and its cofactors C4b-binding protein and factor H by Prevotella intermedia

scientific article

Activation of blood coagulation factor IX by gingipains R, arginine-specific cysteine proteinases from Porphyromonas gingivalis

scientific article

Activation of blood coagulation factor X by arginine-specific cysteine proteinases (gingipain-Rs) from Porphyromonas gingivalis

scientific article published on 01 June 1997

Activation of complement components C3 and C5 by a cysteine proteinase (gingipain-1) from Porphyromonas (Bacteroides) gingivalis.

scientific article

Activation of human prothrombin by arginine-specific cysteine proteinases (Gingipains R) from porphyromonas gingivalis

scientific article

Activation of protease-activated receptors by gingipains from Porphyromonas gingivalis leads to platelet aggregation: a new trait in microbial pathogenicity

scientific article published in June 2001

Activation of protein C by arginine-specific cysteine proteinases (gingipains-R) from Porphyromonas gingivalis

scientific article published on 01 January 1999

Activation of the kallikrein-kinin system and release of new kinins through alternative cleavage of kininogens by microbial and human cell proteinases

scientific article

Adhesive protein-mediated cross-talk between Candida albicans and Porphyromonas gingivalis in dual species biofilm protects the anaerobic bacterium in unfavorable oxic environment

scientific article published on 13 March 2019

Adsorption of components of the plasma kinin-forming system on the surface of Porphyromonas gingivalis involves gingipains as the major docking platforms.

scientific article

Alpha 2-macroglobulin from horse plasma. Purification, properties and interaction with certain serine proteinases

scientific article published on 01 April 1984

Alpha-2-antiplasmin: a serpin with two separate but overlapping reactive sites

scientific article published on 01 August 1988

Amino-acid sequence and three-dimensional structure of the Staphylococcus aureus metalloproteinase at 1.72 A resolution

scientific article

An IgY-based immunoassay to evaluate the biomarker potential of the Tannerella forsythia virulence factor karilysin in human saliva

scientific article published on 14 March 2019

An elastase inhibitor from equine leukocyte cytosol belongs to the serpin superfamily. Further characterization and amino acid sequence of the reactive center ⬇️

scientific article published on May 25, 1988

Analysis of mutations in the SOS-1 gene in two Polish families with hereditary gingival fibromatosis.

scientific article published on 20 April 2017

Analysis of neutrophil-derived antimicrobial peptides in gingival crevicular fluid suggests importance of cathelicidin LL-37 in the innate immune response against periodontogenic bacteria

scientific article published on August 2008

Analysis of oral microbiome from fossil human remains revealed the significant differences in virulence factors of modern and ancient Tannerella forsythia

scientific article published on 15 June 2020

Antibodies to Porphyromonas gingivalis Indicate Interaction Between Oral Infection, Smoking, and Risk Genes in Rheumatoid Arthritis Etiology.

scientific article published on 10 November 2015

Antimicrobial and Attractant Roles for Chemerin in the Oral Cavity during Inflammatory Gum Disease

scientific article published on 29 March 2017

Antimicrobial photodynamic therapy effectively reduces Porphyromonas gingivalis infection in gingival fibroblasts and keratinocytes: An in vitro study

scientific article published in June 2021

Antithrombin III activity (residual thrombin activity) in plasma from non-medicated or heparinized horses

scientific article published on 01 January 1989

Antithrombin III activity in horses with colic: an analysis of 46 cases.

scientific article

Apolipoprotein E Triggers Complement Activation in Joint Synovial Fluid of Rheumatoid Arthritis Patients by Binding C1q

scientific article published on 06 April 2020

Apoptotic cell clearance in chronic inflammation of lateral neck cysts

scientific article published on 14 July 2011

Application of the In Vitro HoxB8 Model System to Characterize the Contributions of Neutrophil-LPS Interaction to Periodontal Disease

scientific article published on 01 July 2020

Are bacterial proteinases pathogenic factors?

scientific article published on October 1995

Arginine-specific cysteine proteinase from porphyromonas gingivalis as a convenient tool in protein chemistry

scientific article published in September 2001

Arginine-specific gingipains from Porphyromonas gingivalis stimulate production of hepatocyte growth factor (scatter factor) through protease-activated receptors in human gingival fibroblasts in culture

scientific article published in November 2005

Arginine-specific protease from Porphyromonas gingivalis activates protease-activated receptors on human oral epithelial cells and induces interleukin-6 secretion

scientific article

Aristolochic acid I determine the phenotype and activation of macrophages in acute and chronic kidney disease

scientific article published in Scientific Reports

Association of Distinct Fine Specificities of Anti-Citrullinated Peptide Antibodies With Elevated Immune Responses to Prevotella intermedia in a Subgroup of Patients With Rheumatoid Arthritis and Periodontitis

scientific article published on 30 October 2017

Attenuated kinin release from human neutrophil elastase-pretreated kininogens by tissue and plasma kallikreins

scientific article

Aureolysin

Aza-peptide Michael acceptors: a new class of inhibitors specific for caspases and other clan CD cysteine proteases

scientific article published in April 2004

BET Bromodomain Inhibitors Suppress Inflammatory Activation of Gingival Fibroblasts and Epithelial Cells From Periodontitis Patients

scientific article published on 30 April 2019

Bacterial and human peptidylarginine deiminases: targets for inhibiting the autoimmune response in rheumatoid arthritis?

scientific article

Bacterial peptidases

scientific article published in January 2005

Bacterial proteases in disease - role in intracellular survival, evasion of coagulation/ fibrinolysis innate defenses, toxicoses and viral infections

scientific article published on January 2013

Bacterial proteinases as targets for the development of second-generation antibiotics

scientific article

Benzamidine derivatives inhibit the virulence of Porphyromonas gingivalis

scientific article published on 26 December 2012

Binding of complement inhibitor C4b-binding protein contributes to serum resistance of Porphyromonas gingivalis

scientific article published on October 2008

Biochemical and structural characterization of SplD protease from Staphylococcus aureus

scientific article

Biosynthesis of alpha1-proteinase inhibitor by human lung-derived epithelial cells

scientific article published on March 1997

Biphasic effect of gingipains from Porphyromonas gingivalis on the human complement system

scientific article published on 01 June 2007

Breakdown of albumin and haemalbumin by the cysteine protease interpain A, an albuminase of Prevotella intermedia

scientific article published on 24 September 2015

Calcium Regulates the Activity and Structural Stability of Tpr, a Bacterial Calpain-like Peptidase

scientific article

Carbamylated LL-37 as a modulator of the immune response

scientific article published on 15 February 2016

Carbamylation of immunoglobulin abrogates activation of the classical complement pathway

scientific article

Cartilage proteoglycan degradation by a mouse transformed macrophage cell line is mediated by macrophage metalloelastase

scientific article published in May 1999

Characterisation of a highly specific, endogenous inhibitor of cysteine protease from Staphylococcus epidermidis, a new member of the staphostatin family

scientific article published in June 2004

Characterization of the binding activities of proteinase-adhesin complexes from Porphyromonas gingivalis

scientific article published on May 1996

Characterization of the specificity of arginine-specific gingipains from Porphyromonas gingivalis reveals active site differences between different forms of the enzymes

scientific article published in October 2003

Chemoattractant activity of Staphylococcus aureus serine proteinase modified human plasma alpha-1-proteinase inhibitor

scientific article published on 01 November 1989

Cibacron Blue-induced modification of neutral proteinase from horse blood leukocytes.

scientific article published in January 1982

Cigarette smoke-exposed neutrophils die unconventionally but are rapidly phagocytosed by macrophages ⬇️

scientific article published on March 17, 2011

Circumferential multiple radial visually-controlled urethrotomy

scientific article published on 01 January 1983

Citrullination alters immunomodulatory function of LL-37 essential for prevention of endotoxin-induced sepsis.

scientific article

Citrullination and proteolytic processing of chemokines by Porphyromonas gingivalis.

scientific article

Citrullination as a plausible link to periodontitis, rheumatoid arthritis, atherosclerosis and Alzheimer’s disease.

scientific article

Citrullination in the periodontium--a possible link between periodontitis and rheumatoid arthritis.

scientific article published on 13 August 2015

Citrullinome of Porphyromonas gingivalis Outer Membrane Vesicles: Confident Identification of Citrullinated Peptides

scientific article published on 21 November 2019

Cleavage and activation of proteinase-activated receptor-2 on human neutrophils by gingipain-R from Porphyromonas gingivalis

article

Cleavage of IgG1 and IgG3 by gingipain K from Porphyromonas gingivalis may compromise host defense in progressive periodontitis.

scientific article

Cleavage of IgG1 in gingival crevicular fluid is associated with the presence of Porphyromonas gingivalis

scientific article published on November 2012

Cleavage of extracellular matrix in periodontitis: gingipains differentially affect cell adhesion activities of fibronectin and tenascin-C.

scientific article

Cleavage of host cytokeratin-6 by lysine-specific gingipain induces gingival inflammation in periodontitis patients

scientific article

Cleavage of human complement component C5 by cysteine proteinases from Porphyromonas (Bacteroides) gingivalis. Prior oxidation of C5 augments proteinase digestion of C5

scientific article published on 01 April 1996

Cleavage of human immunoglobulins by proteinase from Staphylococcus aureus

scientific article published on 01 January 1995

Cleavage of human immunoglobulins by serine proteinase from Staphylococcus aureus

scientific article published on February 15, 1992

Cleavage of the human C5A receptor by proteinases derived from Porphyromonas gingivalis: cleavage of leukocyte C5a receptor

scientific article

Comparative cleavage sites within the reactive-site loop of native and oxidized alpha1-proteinase inhibitor by selected bacterial proteinases

scientific article published on 01 October 1999

Comparative properties of human alpha-1-proteinase inhibitor glycosylation variants

scientific article published on October 1990

Comparative properties of three functionally different but structurally related serpin variants from horse plasma

scientific article published on March 1991

Comparative properties of two cysteine proteinases (gingipains R), the products of two related but individual genes of Porphyromonas gingivalis

scientific article

Comparison of antiproteolytic activities of alpha-1-proteinase inhibitors from the plasma of some mammalian species

scientific article published on 01 January 1986

Comparison of gingival crevicular fluid sampling methods in patients with severe chronic periodontitis.

scientific article

Comparison of pathogenic properties between two types of arginine-specific cysteine proteinases (gingipains-R) from Porphyromonas gingivalis

scientific article published on 01 September 2000

Comparison of specificity of human and horse leucocyte proteinases with synthetic peptide substrates

scientific article published in January 1986

Complement Activation as a Helping Hand for Inflammophilic Pathogens and Cancer

Complementary Tolls in the periodontium: how periodontal bacteria modify complement and Toll-like receptor responses to prevail in the host

scientific article published on February 2010

Concentration of antibodies against Porphyromonas gingivalis is increased before the onset of symptoms of rheumatoid arthritis

scientific article published on 07 September 2016

Conjugate of Enkephalin and Temporin Peptides as a Novel Therapeutic Agent for Sepsis

scientific article published on 10 December 2018

Coordinate expression of the Porphyromonas gingivalis lysine-specific gingipain proteinase, Kgp, arginine-specific gingipain proteinase, RgpA, and the heme/hemoglobin receptor, HmuR.

scientific article published in November 2004

Correction: HmuY Haemophore and Gingipain Proteases Constitute a Unique Syntrophic System of Haem Acquisition by Porphyromonas gingivalis.

scientific article published on 4 March 2011

Correction: HmuY Haemophore and Gingipain Proteases Constitute a Unique Syntrophic System of Haem Acquisition by Porphyromonas gingivalis.

scientific article

Correction: Interpain A, a Cysteine Proteinase from Prevotella intermedia, Inhibits Complement by Degrading Complement Factor C3.

scientific article published on 10 March 2009

Correction: Pyocycanin, a Contributory Factor in Haem Acquisition and Virulence Enhancement of Porphyromonas gingivalis in the Lung

scientific article published on 25 January 2016

Corruption of innate immunity by bacterial proteases

scientific article

Crystal structure of cleaved equine leucocyte elastase inhibitor determined at 1.95 A resolution

scientific article published on August 20, 1992

Crystal structure of gingipain R: an Arg-specific bacterial cysteine proteinase with a caspase-like fold

scientific article

Crystallization and preliminary X‐ray diffraction analysis of gingipain R2 from Porphyromonas gingivalis in complex with H‐D‐Phe‐Phe‐Arg‐chloromethylketone ⬇️

scientific article published on May 1, 1998

Cytoplasmic control of premature activation of a secreted protease zymogen: deletion of staphostatin B (SspC) in Staphylococcus aureus 8325-4 yields a profound pleiotropic phenotype

scientific article

Degradation of elastin by a cysteine proteinase from Staphylococcus aureus.

scientific article

Degradation of fibrinogen and collagen by staphopains, cysteine proteases released from Staphylococcus aureus

scientific article published on 16 November 2010

Degradation of host heme proteins by lysine- and arginine-specific cysteine proteinases (gingipains) of Porphyromonas gingivalis.

scientific article

Degradation of human antimicrobial peptide LL-37 by Staphylococcus aureus-derived proteinases

scientific article published on December 2004

Dentipain, a Streptococcus pyogenes IdeS protease homolog, is a novel virulence factor of Treponema denticola

scientific article

Dependence of vascular permeability enhancement on cysteine proteinases in vesicles of Porphyromonas gingivalis

scientific article

Detection of Porphyromonas gingivalis in gingival exudate by a dipeptide-enhanced trypsin-like activity

scientific article published on January 1994

Development and binding characteristics of phosphonate inhibitors of SplA protease from Staphylococcus aureus

scientific article

Development of Chemical Tools to Monitor Human Kallikrein 13 (KLK13) Activity ⬇️

article

Development of loop-mediated isothermal amplification assay for detection of human coronavirus-NL63

article

Diagnostic evaluation of a nanobody with picomolar affinity toward the protease RgpB from Porphyromonas gingivalis

scientific article

Dichotomy of gingipains action as virulence factors: from cleaving substrates with the precision of a surgeon's knife to a meat chopper-like brutal degradation of proteins.

scientific article

Differential regulation by Toll-like receptor agonists reveals that MCPIP1 is the potent regulator of innate immunity in bacterial and viral infections

scientific article published on 06 July 2012

Disruption of gingipain oligomerization into non-covalent cell-surface attached complexes.

scientific article

Does the importance of the C-terminal residues in the maturation of RgpB from Porphyromonas gingivalis reveal a novel mechanism for protein export in a subgroup of Gram-Negative bacteria?

scientific article published on December 2006

Down-regulation of human extracellular cysteine protease inhibitors by the secreted staphylococcal cysteine proteases, staphopain A and B.

scientific article published in April 2007

Dual regulation of interleukin-8 production in human oral epithelial cells upon stimulation with gingipains from Porphyromonas gingivalis

scientific article

Effect of calcium binding on conformational changes of staphylococcal metalloproteinase measured by means of intrinsic protein fluorescence

scientific article published on 01 June 1986

Effect of dexamethasone on alpha 1-proteinase inhibitor synthesis in human cells of monocytic origin

scientific article published on March 1995

Effect of free and vesicle-bound cysteine proteinases of Porphyromonas gingivalis on plasma clot formation: implications for bleeding tendency at periodontitis sites ⬇️

scientific article published on December 1, 1995

Effect of metalloproteinase from Staphylococcus aureus on in vitro stimulation of human lymphocytes

scientific article published in March 1991

Effect of serine proteinase from Staphylococcus aureus on in vitro stimulation of human lymphocytes

scientific article published on 01 October 1988

Effects of elastase and cathepsin G on the levels of membrane and soluble TNFalpha

scientific article

Effects of serine proteinase from Staphylococcus aureus V8 cells on Con A stimulation of human lymphocytes

scientific article published on 01 April 1989

Effects of statins on multispecies oral biofilm identify simvastatin as a drug candidate targeting Porphyromonas gingivalis

scientific article published on 26 December 2018

Elafin is specifically inactivated by RgpB from Porphyromonas gingivalis by distinct proteolytic cleavage

scientific article published on December 2009

Elastase inhibitor from mammalian neutrophil cytosol

scientific article published on January 1, 1991

Elastinolytic activity of horse leukocyte proteinases. Comparison with elastases from human leukocytes and porcine pancreas

scientific article published in January 1986

Emerging family of proline-specific peptidases of Porphyromonas gingivalis: purification and characterization of serine dipeptidyl peptidase, a structural and functional homologue of mammalian prolyl dipeptidyl peptidase IV

scientific article

Enuresis uretica

scientific article published on 01 October 1972

Enzymatic activity of the Staphylococcus aureus SplB serine protease is induced by substrates containing the sequence Trp-Glu-Leu-Gln

scientific article

Epigenetic regulation in bacterial infections: targeting histone deacetylases

scientific article published on 3 October 2017

Epigenetic regulation of inflammation in periodontitis: cellular mechanisms and therapeutic potential

scientific article published on 30 November 2020

Equine leukocyte elastase inhibitor. Primary structure and identification as a thymosin-binding protein

scientific article

Erratum to: Concentration of antibodies against Porphyromonas gingivalisis increased before the onset of symptoms of rheumatoid arthritis

scientific article published on 4 November 2016

Erratum to: Smoking, Porphyromonas gingivalis and the immune response to citrullinated autoantigens before the clinical onset of rheumatoid arthritis in a Southern European nested case-control study

scientific article published on 5 February 2016

Evidence of mutualism between two periodontal pathogens: co-operative haem acquisition by the HmuY haemophore of Porphyromonas gingivalis and the cysteine protease interpain A (InpA) of Prevotella intermedia

scientific article

Exploring the Sn binding pockets in gingipains by newly developed inhibitors: structure-based design, chemistry, and activity

scientific article published in March 2006

Expression of human and Porphyromonas gingivalis glutaminyl cyclases in periodontitis and rheumatoid arthritis-A pilot study

scientific article published on 28 October 2018

FACIN, a Double-Edged Sword of the Emerging Periodontal Pathogen Filifactor alocis: A Metabolic Enzyme Moonlighting as a Complement Inhibitor.

scientific article published on 16 September 2016

Fibroblasts from recurrent fibrotic overgrowths reveal high rate of proliferation in vitro - findings from the study of hereditary and idiopathic gingival fibromatosis

scientific article published on 20 September 2018

Fighting an enemy within: cytoplasmic inhibitors of bacterial cysteine proteases.

scientific article published in August 2005

Filifactor alocis infection and inflammatory responses in the mouse subcutaneous chamber model

scientific article published on 30 December 2013

Friendly fire against neutrophils: proteolytic enzymes confuse the recognition of apoptotic cells by macrophages

scientific article published on 22 September 2007

Functional Analysis of Porphyromonas gingivalis W83 CRISPR-Cas Systems.

scientific article published on 26 May 2015

Functional and structural characterization of Spl proteases from Staphylococcus aureus

scientific article published on 13 February 2006

Functional characteristics of antibodies induced by Arg-gingipain (HRgpA) and Lys-gingipain (Kgp) from Porphyromonas gingivalis

scientific article published in August 2001

Genes Contributing to Porphyromonas gingivalis Fitness in Abscess and Epithelial Cell Colonization Environments

scientific article published on 28 August 2017

Genetic Variation of Porphyromonas gingivalis Genes Encoding Gingipains, Cysteine Proteinases with Arginine or Lysine Specificity ⬇️

scientific article published on February 1, 1998

Genetic characterization of staphopain genes in Staphylococcus aureus

scientific article published in November 2004

Genome Sequence of Porphyromonas gingivalis Strain HG66 (DSM 28984).

scientific article

Germinal testicular tumors

scientific article published on October 21, 1976

Gingipain K

article

Gingipain R

article published in 2013

Gingipain aminopeptidase activities in Porphyromonas gingivalis

scientific article

Gingipain enzymes from Porphyromonas gingivalis preferentially bind immobilized extracellular proteins: a mechanism favouring colonization?

scientific article

Gingipains from Porphyromonas gingivalis W83 induce cell adhesion molecule cleavage and apoptosis in endothelial cells

scientific article

Gingipains from Porphyromonas gingivalis W83 synergistically disrupt endothelial cell adhesion and can induce caspase-independent apoptosis

scientific article

Gingipains from Porphyromonas gingivalis synergistically induce the production of proinflammatory cytokines through protease-activated receptors with Toll-like receptor and NOD1/2 ligands in human monocytic cells

scientific article published on 7 January 2008

Gingipains impair attachment of epithelial cell to dental titanium abutment surfaces

scientific article published on 14 February 2019

Gingipains of Porphyromonas gingivalis Affect the Stability and Function of Serine Protease Inhibitor of Kazal-type 6 (SPINK6), a Tissue Inhibitor of Human Kallikreins

scientific article published on 27 June 2016

Gingipains, the major cysteine proteinases and virulence factors of Porphyromonas gingivalis: structure, function and assembly of multidomain protein complexes

scientific article published on December 2003

Gingipains: Critical Factors in the Development of Aspiration Pneumonia Caused by Porphyromonas gingivalis

scientific article published on 28 November 2015

Gingival Fibromatosis with Significant De Novo Formation of Fibrotic Tissue and a High Rate of Recurrence.

scientific article

Gingival fibromatosis: clinical, molecular and therapeutic issues

scientific article

Glutaminyl cyclases as novel targets for the treatment of septic arthritis

scientific article published on 29 November 2012

Grafting of antibodies inside integrated microfluidic-microoptic devices by means of automated microcontact printing

scientific article published on June 2009

Growth phase-dependent production of a cell wall-associated elastinolytic cysteine proteinase by Staphylococcus epidermidis

scientific article published on June 2004

HDAC3 Regulates Gingival Fibroblast Inflammatory Responses in Periodontitis.

scientific article

Heightened immune response to autocitrullinated Porphyromonas gingivalis peptidylarginine deiminase: a potential mechanism for breaching immunologic tolerance in rheumatoid arthritis.

scientific article published on 05 March 2013

Heparin-dependent Modification of the Reactive Center Arginine of Antithrombin and Consequent Increase in Heparin Binding Affinity ⬇️

scientific article published on August 8, 1997

HexaPrime: a novel method for detection of coronaviruses

scientific article published on 7 December 2012

High molecular weight gingipains from Porphyromonas gingivalis induce cytokine responses from human macrophage-like cells via a nonproteolytic mechanism

scientific article

HmuY haemophore and gingipain proteases constitute a unique syntrophic system of haem acquisition by Porphyromonas gingivalis

scientific article

Horse leucocyte proteinase-inhibitor system. Kinetic parameters of the inhibition reaction

scientific article published on 01 January 1985

Host andPorphyromonas gingivalis proteinases in periodontitis: A biochemical model of infection and tissue destruction

article

Host cell-surface proteins as substrates of gingipains, the main proteases of Porphyromonas gingivalis

scientific article published on 01 November 2018

Human SCCA Serpins Inhibit Staphylococcal Cysteine Proteases by Forming Classic “Serpin-Like” Covalent Complexes

scientific article published on January 1, 2011

Human coronavirus NL63 utilizes heparan sulfate proteoglycans for attachment to target cells

scientific article

Hydrolysis of epithelial junctional proteins by Porphyromonas gingivalis gingipains

scientific article published on May 2002

Identification and characterization of sigma, a novel component of the Staphylococcus aureus stress and virulence responses

scientific article

Identification of Staphylococcus aureus in homogenates of hypertrophic adenoid (a preliminary report)

scientific article published on January 1, 2010

Identification of an intracellular M17 family leucine aminopeptidase that is required for virulence in Staphylococcus aureus.

scientific article

Identification of bacterial biofilm and the Staphylococcus aureus derived protease, staphopain, on the skin surface of patients with atopic dermatitis

scientific article

Immunomodulatory Molecule IRAK-M Balances Macrophage Polarization and Determines Macrophage Responses during Renal Fibrosis.

scientific article published on 12 July 2017

Impact of Porphyromonas gingivalis Peptidylarginine Deiminase on Bacterial Biofilm Formation, Epithelial Cell Invasion, and Epithelial Cell Transcriptional Landscape

scientific article published on 20 September 2018

In vitro testing the potential of a novel chimeric IgG variant for inhibiting collagen fibrils formation in recurrent hereditary gingival fibromatosis: chimeric antibody in a gingival model

scientific article published on 01 August 2014

In vivo expression of proteases and protease inhibitor, a serpin, by periodontal pathogens at teeth and implants.

scientific article published on 17 April 2018

In vivo sortase A and clumping factor A mRNA expression during Staphylococcus aureus infection

scientific article published on 21 August 2007

Inactivation of epidermal growth factor by Porphyromonas gingivalis as a potential mechanism for periodontal tissue damage

scientific article published on 22 October 2012

Inactivation of membrane tumor necrosis factor alpha by gingipains from Porphyromonas gingivalis

scientific article

Inactivation of tumor necrosis factor-alpha by proteinases (gingipains) from the periodontal pathogen, Porphyromonas gingivalis. Implications of immune evasion

scientific article published on March 1998

Inactivation of α1-Proteinase Inhibitor as a Broad Screen for Detecting Proteolytic Activities in Unknown Samples ⬇️

scientific article published on July 1, 1998

Inactive Gingipains from P. gingivalis Selectively Skews T Cells toward a Th17 Phenotype in an IL-6 Dependent Manner

scientific article

Indications for conservative and operative treatment of closed kidney injuries ⬇️

scientific article

Induction of vascular leakage through release of bradykinin and a novel kinin by cysteine proteinases from Staphylococcus aureus

scientific article

Infection with human coronavirus NL63 enhances streptococcal adherence to epithelial cells

scientific article

Inhibition of CDK9 as a therapeutic strategy for inflammatory arthritis

scientific article

Inhibition of GSK3 abolishes bacterial-induced periodontal bone loss in mice.

scientific article

Inhibition of Porphyromonas gingivalis proteinases (gingipains) by chlorhexidine: synergistic effect of Zn(II)

scientific article published on 01 August 2006

Inhibition of Staphylococcus aureus cysteine proteases by human serpin potentially limits staphylococcal virulence

scientific article published on May 2011

Inhibition of arginine gingipains (RgpB and HRgpA) with benzamidine inhibitors: zinc increases inhibitory potency

scientific article published in July 2002

Inhibition of distant caspase homologues by natural caspase inhibitors

scientific article

Inhibition of gingipains and Porphyromonas gingivalis growth and biofilm formation by prenyl flavonoids

scientific article

Inhibition of gingipains by their profragments as the mechanism protecting Porphyromonas gingivalis against premature activation of secreted proteases

scientific article published on 10 April 2013

Inhibition of horse leucocyte proteinases by eglin, a proteinase inhibitor from leeches

Inhibition of trypsin-like cysteine proteinases (gingipains) from Porphyromonas gingivalis by tetracycline and its analogues

scientific article

Inhibition of tumor necrosis factor-alpha-induced RANTES secretion by alkaline protease in A549 cells

scientific article published on 21 July 2005

Inter-alpha-trypsin inhibitor. Inhibition spectrum of native and derived forms

scientific article published on 01 September 1989

Interaction of a novel form of Pseudomonas aeruginosa alkaline protease (aeruginolysin) with interleukin-6 and interleukin-8

scientific article published on 01 July 2006

Interaction of regulators Mdm2 and Mdmx with transcription factors p53, p63 and p73.

scientific article published on 15 November 2010

Interpain A, a cysteine proteinase from Prevotella intermedia, inhibits complement by degrading complement factor C3.

scientific article published on 27 February 2009

Intracellular Staphylococcus aureus employs the cysteine protease staphopain A to induce host cell death in epithelial cells

scientific article published in September 2021

Introduction to 'gums and joints' special issue. Introduction

scientific article published in December 2014

Investigations into sigmaB-modulated regulatory pathways governing extracellular virulence determinant production in Staphylococcus aureus

scientific article

Isolation and properties of an elastase-like proteinase from horse blood leucocytes

scientific article published on 01 January 1982

Isolation and properties of extracellular proteinases of Penicillium marneffei

scientific article published on July 2006

Isolation of Nine Human Plasma Proteinase Inhibitors by Sequential Affinity Chromatography ⬇️

scientific article published on January 1, 1990

KLIKK proteases of Tannerella forsythia: putative virulence factors with a unique domain structure

scientific article published on 21 April 2015

Kallikrein 13 serves as a priming protease during infection by the human coronavirus HKU1

scientific article published on 24 November 2020

Kallikrein 13: a new player in coronaviral infections

scientific article (preprint)

Kallikrein-Related Peptidase 14 Activates Zymogens of Membrane Type Matrix Metalloproteinases (MT-MMPs)-A CleavEx Based Analysis

scientific article published on 19 June 2020

Kallikreins - The melting pot of activity and function

scientific article published on 23 September 2015

Karilysin, metalloproteinase present in majority of Tannerella forsythia isolates inhibits all pathways of the complement system

scholarly article by J.M. Jusko et al published August 2011 in Molecular Immunology

Kinin danger signals proteolytically released by gingipain induce Fimbriae-specific IFN-gamma- and IL-17-producing T cells in mice infected intramucosally with Porphyromonas gingivalis.

scientific article published on 17 August 2009

Lack of cathelicidin processing in Papillon-Lefèvre syndrome patients reveals essential role of LL-37 in periodontal homeostasis

scientific article

Latency period of urogenital tuberculosis

scientific article published on March 1, 1973

Latency, thermal stability, and identification of an inhibitory compound of mirolysin, a secretory protease of the human periodontopathogen

scientific article published in December 2021

Loss of clumping factor B fibrinogen binding activity by Staphylococcus aureus involves cessation of transcription, shedding and cleavage by metalloprotease

scientific article published on 8 June 2001

Lysine- and arginine-specific proteinases from Porphyromonas gingivalis. Isolation, characterization, and evidence for the existence of complexes with hemagglutinins

scientific article

Lysine-specific gingipain promotes lipopolysaccharide- and active-vitamin D3-induced osteoclast differentiation by degrading osteoprotegerin

scientific article

MCPIP-1, Alias Regnase-1, Controls Epithelial Inflammation by Posttranscriptional Regulation of IL-8 Production.

scientific article

Malignant hypertension in irreparable kidney failure and bilateral nephrectomy

scientific article published on November 10, 1972

Mammalian-like type II glutaminyl cyclases in Porphyromonas gingivalis and other oral pathogenic bacteria as targets for treatment of periodontitis

scientific article published on 05 January 2021

Manipulation of Neutrophils by Porphyromonas gingivalis in the Development of Periodontitis

scientific article

Mechanism of methaemoglobin breakdown by the lysine-specific gingipain of the periodontal pathogen Porphyromonas gingivalis

scientific article published on September 2008

Mechanisms mediating Porphyromonas gingivalis gingipain RgpA-induced oral mucosa inflammation in vivo

scientific article

Mechanisms of vascular damage by systemic dissemination of the oral pathogen Porphyromonas gingivalis

scientific article published on 18 July 2020

Meprin β induces activities of A disintegrin and metalloproteinases 9, 10, and 17 by specific prodomain cleavage

scientific article published on 09 August 2019

Metabolomic Status of The Oral Cavity in Chronic Periodontitis

scientific article published on 01 July 2019

Mirolase, a novel subtilisin-like serine protease from the periodontopathogen Tannerella forsythia

scientific article

Mirolysin, a LysargiNase from Tannerella forsythia, proteolytically inactivates the human cathelicidin, LL-37.

scientific article published on 20 December 2016

Miropin, a novel bacterial serpin from the periodontopathogen Tannerella forsythia, inhibits a broad range of proteases by using different peptide bonds within the reactive center loop

scientific article

Modification of cystatin C activity by bacterial proteinases and neutrophil elastase in periodontitis ⬇️

scientific article published on December 1, 1997

Modulation of interleukin-8 activity by gingipains from Porphyromonas gingivalis: implications for pathogenicity of periodontal disease

scientific article published on 01 December 1998

Molecular cloning and characterization of Porphyromonas gingivalis lysine-specific gingipain. A new member of an emerging family of pathogenic bacterial cysteine proteinases

scientific article published in January 1997

Molecular cloning and structural characterization of the Arg-gingipain proteinase of Porphyromonas gingivalis. Biosynthesis as a proteinase-adhesin polyprotein

scientific article

Molecular diversity of a putative virulence factor: purification and characterization of isoforms of an extracellular serine glutamyl endopeptidase of Enterococcus faecalis with different enzymatic activities

scientific article

Molecular genetics and nomenclature of proteases of Porphyromonas gingivalis

scientific article

Mucus Detachment by Host Metalloprotease Meprin β Requires Shedding of Its Inactive Pro-form, which Is Abrogated by the Pathogenic Protease RgpB.

scientific article published in November 2017

Murine myeloid cell MCPIP1 suppresses autoimmunity by regulating B-cell expansion and differentiation

scientific article published on 18 March 2021

Neuropeptide release from dental pulp cells by RgpB via proteinase-activated receptor-2 signaling

scientific article

Neutrophil proteinases. Caution signs in designing inhibitors against enzymes with possible multiple functions

scientific article published on January 1991

Neutrophils in chronic and aggressive periodontitis in interaction with Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans

scientific article

New method for typing Staphylococcus aureus strains: multiple-locus variable-number tandem repeat analysis of polymorphism and genetic relationships of clinical isolates

scientific article

Noncanonical activation of β-catenin by Porphyromonas gingivalis

scientific article published in June 2015

Noncatalytic protein component of elastase from horse leucocytes. A protein with regulatory function

scientific article published on 01 January 1988

Novel polymeric inhibitors of HCoV-NL63.

scientific article published on 29 November 2012

NsaRS is a cell-envelope-stress-sensing two-component system of Staphylococcus aureus

scientific article

On the transcriptional regulation of methicillin resistance: MecI repressor in complex with its operator

scientific article

Oncostatin M stimulates the expression and release of the IL-6 receptor in human hepatoma HepG2 cells

Optimal time for treating cryptorchism (author's transl) ⬇️

scientific article published on March 28, 1975

Organ-preserving surgical therapy of the transverse rupture of the kidney

scientific article published on 01 November 1967

Origin of circulating acute phase cytokines: modified proteins may trigger IL-6 production by macrophages. Preliminary report.

scientific article

PATHOGENESIS AND CLINICAL ASPECTS OF BLADDER ENDOMETRIOSIS

scientific article published on 01 September 1963

PPAD remains a credible candidate for inducing autoimmunity in rheumatoid arthritis: comment on the article by Konig et al.

scientific article

Papain-like proteases of Staphylococcus aureus

scientific article published on January 2011

Pathogenesis of periodontitis: a major arginine-specific cysteine proteinase from Porphyromonas gingivalis induces vascular permeability enhancement through activation of the kallikrein/kinin pathway

scientific article

Peptidyl arginine deiminase from Porphyromonas gingivalis abolishes anaphylatoxin C5a activity

scientific article

Peptidylarginine Deiminase of Porphyromonas gingivalis Modulates the Interactions between Candida albicans Biofilm and Human Plasminogen and High-Molecular-Mass Kininogen

scientific article published on 03 April 2020

Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and α-enolase: implications for autoimmunity in rheumatoid arthritis

scientific article

Peptidylarginine deiminase from Porphyromonas gingivalis contributes to infection of gingival fibroblasts and induction of prostaglandin E2 -signaling pathway.

scientific article

Periodontal Pathogens and Associated Intrathecal Antibodies in Early Stages of Alzheimer's Disease

scientific article published on 01 January 2018

Periodontal pathogens affect the level of protease inhibitors in gingival crevicular fluid.

scientific article published on 7 December 2011

Phagocytosis of Staphylococcus aureus by macrophages exerts cytoprotective effects manifested by the upregulation of antiapoptotic factors

scientific article

Pharmacokinetics of sulbactam and ampicillin intravenously applied in combination to healthy volunteers and patients. Determination of the ratio of the two drugs in serum and in various tissues

scientific article published on 01 November 1988

Plasmin inhibition by bacterial serpin: Implications in gum disease

scientific article published on 26 November 2019

Poison-antidote systems in bacteria: the co-evolution of functional counterparts.

scientific article published on 31 December 2006

Porphyromonas gingivalis DPP-7 represents a novel type of dipeptidylpeptidase

scientific article

Porphyromonas gingivalis HmuY and HmuR: further characterization of a novel mechanism of heme utilization

scientific article published on 06 October 2007

Porphyromonas gingivalis Peptidyl Arginine Deiminase Can Modulate Neutrophil Activity via Infection of Human Dental Stem Cells

scientific article published on 01 June 2018

Porphyromonas gingivalis Virulence Factor Gingipain RgpB Shows a Unique Zymogenic Mechanism for Cysteine Peptidases

scientific article

Porphyromonas gingivalis enzymes enhance infection with human metapneumovirus in vitro

scientific article published on 29 June 2011

Porphyromonas gingivalis facilitates the development and progression of destructive arthritis through its unique bacterial peptidylarginine deiminase (PAD)

scientific article published in September 2013

Porphyromonas gingivalis fimbriae dampen P2X7-dependent interleukin-1β secretion.

scientific article

Porphyromonas gingivalis genes conferring fitness in a tobacco-rich environment

scientific article published on 18 December 2019

Porphyromonas gingivalis gingipains selectively reduce CD14 expression, leading to macrophage hyporesponsiveness to bacterial infection

scientific article

Porphyromonas gingivalis in Alzheimer's disease brains: Evidence for disease causation and treatment with small-molecule inhibitors.

scientific article published on 23 January 2019

Porphyromonas gingivalis induce apoptosis in human gingival epithelial cells through a gingipain-dependent mechanism

scientific article

Porphyromonas gingivalis proteinases as virulence factors in the development of periodontitis

scientific article published on January 1997

Porphyromonas gingivalis proteinases in periodontitis, a review

scientific article

Porphyromonas gingivalis-derived lysine gingipain enhances osteoclast differentiation induced by tumor necrosis factor-α and interleukin-1β but suppresses that by interleukin-17A: importance of proteolytic degradation of osteoprotegerin by lysine gi

scientific article

Porphyromonas gingivalis: a proteinase/gene accounting audit

scientific article published on November 1995

Posttranslational Modifications in Innate Immunity ⬇️

scientific article published on January 27, 2012

Presence of Porphyromonas gingivalis in esophagus and its association with the clinicopathological characteristics and survival in patients with esophageal cancer

scientific article

Prevalence of genes encoding extracellular proteases in Staphylococcus aureus - important targets triggering immune response in vivo.

scientific article

Preventive medical check up for rectal and prostatic carcinoma

scientific article published on 01 July 1972

Prokaryote-derived protein inhibitors of peptidases: A sketchy occurrence and mostly unknown function

scientific article

Prolyl tripeptidyl peptidase from Porphyromonas gingivalis. A novel enzyme with possible pathological implications for the development of periodontitis

scientific article

Prostaphopain B structure: a comparison of proregion-mediated and staphostatin-mediated protease inhibition

scientific article published on November 2004

Protease-armed bacteria in the skin

scientific article

Protease-dependent mechanisms of complement evasion by bacterial pathogens ⬇️

scientific article published on September 1, 2012

Proteases of periodontal pathogens Porphyromonas gingivalis, Tannerella forsythia and Prevotella intermedia target all pathways of the complement system

scholarly article by Monika Jusko et al published August 2010 in Molecular Immunology

Proteinase-mediated release of epithelial cell-associated CD44. Extracellular CD44 complexes with components of cellular matrices

scientific article published on 10 September 2002

Proteolysis of CD14 on human gingival fibroblasts by arginine-specific cysteine proteinases from Porphyromonas gingivalis leading to down-regulation of lipopolysaccharide-induced interleukin-8 production

scientific article published on June 2002

Proteolysis of Gingival Keratinocyte Cell Surface Proteins by Gingipains Secreted From Porphyromonas gingivalis - Proteomic Insights Into Mechanisms Behind Tissue Damage in the Diseased Gingiva

scientific article published on 28 April 2020

Proteolysis of ICAM-1 on Human Oral Epithelial Cells by Gingipains ⬇️

scientific article published on October 1, 2003

Proteolysis of interleukin-6 receptor (IL-6R) by Porphyromonas gingivalis cysteine proteinases (gingipains) inhibits interleukin-6-mediated cell activation

scientific article

Proteolytic effects of gingipains on trefoil factor family peptides

scientific article published on 19 July 2017

Proteolytic inactivation of LL-37 by karilysin, a novel virulence mechanism of Tannerella forsythia

scientific article

Proteolytic inactivation of alpha-1-anti-chymotrypsin. Sites of cleavage and generation of chemotactic activity ⬇️

scientific article published on November 15, 1991

Proteolytic inactivation of the leukocyte C5a receptor by proteinases derived from Porphyromonas gingivalis

scientific article

Proteolytic processing and activation of gingipain zymogens secreted by T9SS of Porphyromonas gingivalis

scientific article published on 15 June 2019

Purification and Characterization of an Arginine-specific Peptidase from Ragweed (Ambrosia artemisiifolia) Pollen ⬇️

scientific article published on March 1, 1998

Purification and characterisation of recombinant His-tagged RgpB gingipain from Porphymonas gingivalis

scientific article

Purification and characterization of a 50-kDa cysteine proteinase (gingipain) from Porphyromonas gingivalis ⬇️

scientific article published on September 15, 1992

Purification and characterization of a novel cysteine proteinase (periodontain) from Porphyromonas gingivalis. Evidence for a role in the inactivation of human alpha1-proteinase inhibitor

scientific article published on 01 April 1999

Purification and characterization of a novel endopeptidase in ragweed (Ambrosia artemisiifolia) pollen

scientific article published on October 1996

Purification and characterization of gingipains

scientific article published on August 2007

Purification, characterization, and sequence analysis of a potential virulence factor from Porphyromonas gingivalis, peptidylarginine deiminase

scientific article

Pyocyanina contributory factor in haem acquisition and virulence enhancement of Porphyromonas gingivalis in the lung [corrected]

scientific article

Rapid and efficient inactivation of IL-6 gingipains, lysine- and arginine-specific proteinases from Porphyromonas gingivalis

scientific article published on 01 August 1999

Regulation of alpha 1-antichymotrypsin synthesis in cells of epithelial origin

scientific article published on 01 February 1995

Regulation of chemerin chemoattractant and antibacterial activity by human cysteine cathepsins

scientific article published on 29 June 2011

Relationship between past myocardial infarction, periodontal disease and Porphyromonas gingivalis serum antibodies: A case-control study

scientific article

Release of a new vascular permeability enhancing peptide from kininogens by human neutrophil elastase

scientific article published in June 2002

Ribonucleotide reductase class III, an essential enzyme for the anaerobic growth of Staphylococcus aureus, is a virulence determinant in septic arthritis

scientific article published on 25 May 2007

Role of OmpA2 surface regions of Porphyromonas gingivalis in host-pathogen interactions with oral epithelial cells.

scientific article

Role of bacterial proteinases in matrix destruction and modulation of host responses

scientific article

Role of gingipains R in the pathogenesis of Porphyromonas gingivalis-mediated periodontal disease

scientific article

Role of rubrerythrin in the oxidative stress response of Porphyromonas gingivalis

scientific article

Role of the cysteine protease interpain A of Prevotella intermedia in breakdown and release of haem from haemoglobin

scientific article

Roles of the host oxidative immune response and bacterial antioxidant rubrerythrin during Porphyromonas gingivalis infection.

scientific article

Salivary histatin 5 is an inhibitor of both host and bacterial enzymes implicated in periodontal disease

scientific article

Secretory leukocyte proteinase inhibitor-competent DNA deposits are potent stimulators of plasmacytoid dendritic cells: implication for psoriasis

scientific article published on 11 July 2012

Selective inhibition of Porphyromonas gingivalis growth by a factor Xa inhibitor, DX-9065a

scientific article published on 01 June 2006

Sequence-independent processing site of the C-terminal domain (CTD) influences maturation of the RgpB protease from Porphyromonas gingivalis

scientific article published on 19 July 2013

Sequential action of R- and K-specific gingipains of Porphyromonas gingivalis in the generation of the haem-containing pigment from oxyhaemoglobin

scientific article published on 04 June 2007

Sequential autolytic processing activates the zymogen of Arg-gingipain

scientific article published on 17 January 2003

Serpin alpha 1proteinase inhibitor probed by intrinsic tryptophan fluorescence spectroscopy

scientific article

Serpins: structure and mechanism of action

scientific article published on May 1990

Site-specific O-glycosylation on the MUC2 mucin protein inhibits cleavage by the Porphyromonas gingivalis secreted cysteine protease (RgpB).

scientific article published on April 2013

Smoking, Porphyromonas gingivalis and the immune response to citrullinated autoantigens before the clinical onset of rheumatoid arthritis in a Southern European nested case-control study

scientific article published on 4 November 2015

Spontaneous inactivation of human lung tryptase as probed by size-exclusion chromatography and chemical cross-linking: dissociation of active tetrameric enzyme into inactive monomers is the primary event of the entire process ⬇️

scientific article published on June 11, 1998

Stability of infectious human coronavirus NL63.

scientific article published on 18 April 2014

Stabilization vs. degradation of Staphylococcus aureus metalloproteinase

scientific article

Staphopain A

Staphostatins resemble lipocalins, not cystatins in fold

scientific article

Staphostatins: an expanding new group of proteinase inhibitors with a unique specificity for the regulation of staphopains, Staphylococcus spp. cysteine proteinases

scientific article

Staphylococcal SplB Serine Protease Utilizes a Novel Molecular Mechanism of Activation

scientific article

Staphylococcal cysteine protease staphopain B (SspB) induces rapid engulfment of human neutrophils and monocytes by macrophages

scientific article published in April 2009

Staphylococcal proteases aid in evasion of the human complement system

scientific article

Staphylococcus aureus infection triggers production of neutralizing, V8 protease-specific antibodies

scientific article published on 16 January 2008

Staphylococcus aureus proteases degrade lung surfactant protein A potentially impairing innate immunity of the lung

scientific article published on 11 December 2012

Staphylococcus aureus-derived staphopain B, a potent cysteine protease activator of plasma chemerin.

scientific article published in March 2007

Stimulation of proteinase and amidase activities in Porphyromonas (Bacteroides) gingivalis by amino acids and dipeptides

scientific article published on August 1991

Stimulatory effect of inflammatory cytokines on alpha 1-antichymotrypsin expression in human lung-derived epithelial cells

scientific article published on June 1995

Strategies for the inhibition of gingipains for the potential treatment of periodontitis and associated systemic diseases

scientific article published on 18 August 2014

Structural and functional characterization of SplA, an exclusively specific protease of Staphylococcus aureus

scientific article

Structural and functional characterization of elastases from horse neutrophils

scientific article published on June 1994

Structural and functional insights into oligopeptide acquisition by the RagAB transporter from Porphyromonas gingivalis

scientific article published on 11 May 2020

Structural and functional probing of PorZ, an essential bacterial surface component of the type-IX secretion system of human oral-microbiomic Porphyromonas gingivalis.

scientific article

Structural basis for ADP-dependent glucokinase inhibition by 8-bromo-substituted adenosine nucleotide

scientific article published on 21 May 2018

Structural determinants of inhibition of Porphyromonas gingivalis gingipain K by KYT-36, a potent, selective, and bioavailable peptidase inhibitor.

scientific article

Structural insights unravel the zymogenic mechanism of the virulence factor gingipain K from Porphyromonas gingivalis, a causative agent of gum disease from the human oral microbiome

scientific article

Structure and mechanism of a bacterial host-protein citrullinating virulence factor, Porphyromonas gingivalis peptidylarginine deiminase

scientific article published on July 2015

Structure and mechanism of cysteine peptidase gingipain K (Kgp), a major virulence factor of Porphyromonas gingivalis in periodontitis.

scientific article

Structure of RagB, a major immunodominant outer-membrane surface receptor antigen of Porphyromonas gingivalis

scientific article

Structure of the catalytic domain of theTannerella forsythiamatrix metallopeptidase karilysin in complex with a tetrapeptidic inhibitor

scientific article

Structure, function, and inhibition of a genomic/clinical variant of Porphyromonas gingivalis peptidylarginine deiminase

scientific article published on 30 January 2019

Structure-based mechanism of cysteine-switch latency and of catalysis by pappalysin-family metallopeptidases

scientific article published on 01 January 2020

Substrate specificity of Staphylococcus aureus cysteine proteases--Staphopains A, B and C.

scientific article

Subversion of Lipopolysaccharide Signaling in Gingival Keratinocytes via MCPIP-1 Degradation as a Novel Pathogenic Strategy of Inflammophilic Pathobionts

scientific article published on 29 June 2021

TIMP-1 association with collagen type I overproduction in hereditary gingival fibromatosis

scientific article published on 14 August 2018

Tethering soluble meprin α in an enzyme complex to the cell surface affects IBD-associated genes

scientific article published on 27 March 2019

The 1.8 A crystal structure of human cathepsin G in complex with Suc-Val-Pro-PheP-(OPh)2: a Janus-faced proteinase with two opposite specificities

scientific article

The Bactericidal Activity of Temporin Analogues Against Methicillin Resistant Staphylococcus aureus

scientific article published on 25 September 2019

The Bacteroidetes Q-Rule: Pyroglutamate in Signal Peptidase I Substrates

scientific article published in March 2018

The C-terminal domains of the gingipain K polyprotein are necessary for assembly of the active enzyme and expression of associated activities

scientific article published in December 2004

The Clostridium ramosum IgA proteinase represents a novel type of metalloendopeptidase

scientific article published on 28 January 2002

The HA2 haemagglutinin domain of the lysine-specific gingipain (Kgp) of Porphyromonas gingivalis promotes micro-oxo bishaem formation from monomeric iron(III) protoporphyrin IX

scientific article published on 01 June 2006

The Janus face of α-toxin: a potent mediator of cytoprotection in staphylococci-infected macrophages

scientific article

The S-layer proteins of Tannerella forsythia are secreted via a type IX secretion system that is decoupled from protein O-glycosylation.

scientific article

The Staphostatin-staphopain complex: a forward binding inhibitor in complex with its target cysteine protease

scientific article

The Staphylococcus aureus leucine aminopeptidase is localized to the bacterial cytosol and demonstrates a broad substrate range that extends beyond leucine

scientific article published on June 2013

The Type IX Secretion System (T9SS): Highlights and Recent Insights into Its Structure and Function.

scientific article

The activity of bacterial peptidylarginine deiminase is important during formation of dual-species biofilm by periodontal pathogen Porphyromonas gingivalis and opportunistic fungus Candida albicans.

scientific article

The biphasic virulence activities of gingipains: activation and inactivation of host proteins

scientific article published on December 2003

The case for periodontitis in the pathogenesis of rheumatoid arthritis

scientific article published on 24 August 2017

The fluorescence quenching resolved spectra and red-edge excitation fluorescence measurements of human alpha 1-proteinase inhibitor

scientific article published on 01 April 1991

The functional role of acute phase plasma proteinase inhibitors

scientific article published on December 1988

The gingipains from Porphyromonas gingivalis do not directly induce osteoclast differentiation in primary mouse bone marrow cultures.

scientific article

The human fibrinolytic system is a target for the staphylococcal metalloprotease aureolysin

scientific article published on February 2008

The inactivation of human plasma alpha 1-proteinase inhibitor by proteinases from Staphylococcus aureus.

scientific article

The interaction between some serine proteinases and horse leucocyte inhibitor

scientific article published on 01 January 1986

The intrinsic enzymatic activity of procarboxypeptidase U (TAFI) does not significantly influence the fibrinolytic rate: reply to a rebuttal

scientific article published on 01 June 2007

The link between periodontal disease and rheumatoid arthritis: an updated review.

scientific article published in March 2014

The lysine-specific gingipain of Porphyromonas gingivalis : importance to pathogenicity and potential strategies for inhibition

scientific article published on January 2011

The multiple forms of trypsin-like activity present in various strains of Porphyromonas gingivalis are due to the presence of either Arg-gingipain or Lys-gingipain ⬇️

scientific article

The nucleocapsid protein of human coronavirus NL63

scientific article

The operative technic in organ-preserving surgical therapy in transverse rupture of the kidney

scientific article published in December 1968

The outer-membrane export signal of Porphyromonas gingivalis type IX secretion system (T9SS) is a conserved C-terminal β-sandwich domain

scientific article published on 23 March 2016

The potential role of alpha 2-macroglobulin in the control of cysteine proteinases (gingipains) from Porphyromonas gingivalis

scientific article published on 01 January 1997

The presence of apoptotic neutrophils in contents of neck lateral cysts

scientific article published on 01 January 2010

The primary elastase inhibitor (elastasin) and trypsin inhibitor (contrapsin) in the goat are serpins related to human alpha 1-anti-chymotrypsin

scientific article published on February 1995

The role and regulation of the extracellular proteases of Staphylococcus aureus

scientific article

The role of Mcl-1 in S. aureus-induced cytoprotection of infected macrophages

scientific article published on 28 January 2013

The role of bacterial and host proteinases in periodontal disease

scientific article

The role of proteolytic enzymes in the development of pulmonary emphysema and periodontal disease

scientific article published on 01 December 1994

The serpin superfamily of proteinase inhibitors: structure, function, and regulation

scientific article

The staphostatin family of cysteine protease inhibitors in the genus Staphylococcus as an example of parallel evolution of protease and inhibitor specificity.

scientific article published in February 2007

The structure of the catalytic domain of Tannerella forsythia karilysin reveals it is a bacterial xenologue of animal matrix metalloproteinases

scientific article

The use of alpha 2-antiplasmin as a model for the demonstration of complex reversibility in serpins

scientific article published on 01 August 1989

Three-dimensional structure of MecI. Molecular basis for transcriptional regulation of staphylococcal methicillin resistance

scientific article

Thrombin-activable fibrinolysis inhibitor (TAFI) zymogen is an active carboxypeptidase

scientific article

Titration and mapping of the active site of cysteine proteinases from Porphyromonas gingivalis (gingipains) using peptidyl chloromethanes

scientific article

Transposition of the endogenous insertion sequence element IS1126 modulates gingipain expression in Porphyromonas gingivalis

scientific article

Treatment of severe periodontitis may improve clinical disease activity in otherwise treatment-refractory rheumatoid arthritis patients

scientific article published on 01 January 2020

Triggering NETosis via protease-activated receptor (PAR)-2 signaling as a mechanism of hijacking neutrophils function for pathogen benefits

scientific article published on 20 May 2019

Two allelic forms of the aureolysin gene (aur) within Staphylococcus aureus

scientific article

Unaltered expression of the major protease genes in a non-virulent recA-defective mutant of Porphyromonas gingivalis W83.

scientific article published in February 2000

Unique Structure and Stability of HmuY, a Novel Heme-Binding Protein of Porphyromonas gingivalis

scientific article

Unique Substrate Specificity of SplE Serine Protease from Staphylococcus aureus

scientific article published in March 2018

Urethrotomy technique in urethral strictures: 6-year results

scientific article published in May 1983

Use of sensitive, broad-spectrum molecular assays and human airway epithelium cultures for detection of respiratory pathogens

scientific article

Vaccination with recombinant RgpA peptide protects against Porphyromonas gingivalis-induced bone loss

scientific article published on 10 June 2016

Verification of a topology model of PorT as an integral outer-membrane protein in Porphyromonas gingivalis

scientific article published in February 2009

Visualization of kallikreins in thyroid epithelial and carcinoma cells

scholarly article by Eileen Kroll et al published 13 May 2016 in Endocrine Abstracts

Zebrafish as a new model to study effects of periodontal pathogens on cardiovascular diseases.

scientific article published on 25 October 2016

[Etiology of hematuria from the urologic viewpoint]

scientific article published on 01 March 1982

[Evaluation of the method of introduction of intracardiac electrode through the brachiocephalic trunk in the venous angle]

scientific article published on 01 November 1980

[Evolution of the structure and function of serine proteolytic enzymes]

scientific article published on 01 January 1985

[Fertility after orchidopexy]

scientific article published on 01 January 1974

[Forms of administration of ethyl-methyl-propyl thiobarbiturate (inactin) anesthesia in urology]

scientific article published on 01 August 1955

[Histology and diagnosis of vessel-deficient kidney tumors (author's transl)]

scientific article published on 01 January 1974

[Infusion therapy during transurethral prostatectomy]

scientific article published on 01 June 1980

[Prostatic hypertrophy and its treatment]

scientific article published on 01 December 1966

[Results of intravenous Terramycin treatment in urology.]

scientific article published on 01 March 1961

[The ultra-short term anesthetic citoeunarcon in urological practice]

scientific article published on 01 April 1957

[Treatment of prostatic hypertrophy in persons over 70]

scientific article published on 01 October 1966

pH-regulated secretion of a glyceraldehyde-3-phosphate dehydrogenase from Streptococcus gordonii FSS2: purification, characterization, and cloning of the gene encoding this enzyme

scientific article

Paulina is supported by:

About Paulina

Help