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List of works by David R Crosslin

A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects

scientific article published on 12 September 2013

A phenome-wide association study to discover pleiotropic effects of , , and

A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers

scientific article published in Nature Communications

Association of Arrhythmia-Related Genetic Variants With Phenotypes Documented in Electronic Medical Records

scientific article published on January 2016

Association of Genetic Risk of Obesity with Postoperative Complications Using Mendelian Randomization

scientific article published on 01 January 2020

Complement receptor 1 gene variants are associated with erythrocyte sedimentation rate

scientific article

Defining a Contemporary Ischemic Heart Disease Genetic Risk Profile Using Historical Data

scientific article

Detecting potential pleiotropy across cardiovascular and neurological diseases using univariate, bivariate, and multivariate methods on 43,870 individuals from the eMERGE network

Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals

scientific article published on 24 July 2017

Electronic medical records and genomics (eMERGE) network exploration in cataract: several new potential susceptibility loci.

scientific article

Enhancing the power of genetic association studies through the use of silver standard cases derived from electronic medical records

scientific article

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

scientific article

Generalization of variants identified by genome-wide association studies for electrocardiographic traits in African Americans

scientific article published on 28 March 2013

Genetic variants associated with serum thyroid stimulating hormone (TSH) levels in European Americans and African Americans from the eMERGE Network

scientific article

Genetic variation associated with circulating monocyte count in the eMERGE Network

scientific article published on 12 January 2013

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

scientific article published on February 2016

High density GWAS for LDL cholesterol in African Americans using electronic medical records reveals a strong protective variant in APOE

scientific article

Identifying gene-gene interactions that are highly associated with Body Mass Index using Quantitative Multifactor Dimensionality Reduction (QMDR)

scientific article

Imputation and quality control steps for combining multiple genome-wide datasets

scientific article

Investigating the Genetic Architecture of the PR Interval Using Clinical Phenotypes

scientific article published on April 2017

LPA Variants Are Associated With Residual Cardiovascular Risk in Patients Receiving Statins

Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases

scientific article

Loss-of-function mutations in APOC3, triglycerides, and coronary disease

scientific article published on 18 June 2014

Mechanistic phenotypes: an aggregative phenotyping strategy to identify disease mechanisms using GWAS data

scientific article

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci ⬇️

scientific article

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

scientific article published on 28 November 2016

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Penetrance of Hemochromatosis in HFE Genotypes Resulting in p.Cys282Tyr and p.[Cys282Tyr];[His63Asp] in the eMERGE Network

scientific article

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

scientific article published on 29 October 2019

Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index

scientific article

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

scientific article

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 22 December 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 16 March 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 01 July 2019

Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms

scientific article published on 14 July 2016

Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

scientific article

The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future ⬇️

scientific article (publication date: October 2013)

The phenotypic legacy of admixture between modern humans and Neandertals

scientific article

The polygenic architecture of left ventricular mass mirrors the clinical epidemiology

scientific article published on 05 May 2020

Use of diverse electronic medical record systems to identify genetic risk for type 2 diabetes within a genome-wide association study

scientific article published on 19 November 2011

Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol

scientific article

eMERGE Phenome-Wide Association Study (PheWAS) identifies clinical associations and pleiotropy for stop-gain variants

scientific article

eMERGEing progress in genomics-the first seven years

scientific article

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