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List of works by Kobkul Laoteng

3D Structure Modeling of a Transmembrane Protein, Fatty Acid Elongase

A Mucor rouxii mutant with high accumulation of an unusual trans-linoleic acid (9c,12t-C18:2).

scientific article

Alterations in growth and fatty acid profiles under stress conditions of Hansenula polymorpha defective in polyunsaturated fatty acid synthesis

scientific article published on 6 May 2013

Alternative metabolic routes in channeling xylose to cordycepin production of Cordyceps militaris identified by comparative transcriptome analysis

scientific article published on 22 April 2019

Alternative routes of acetyl-CoA synthesis identified by comparative genomic analysis: involvement in the lipid production of oleaginous yeast and fungi

scientific article published on 20 October 2011

Biosynthesis of xyrrolin, a new cytotoxic hybrid polyketide/non-ribosomal peptide pyrroline with anticancer potential, in Xylaria sp. BCC 1067.

scientific article

Comparative fatty acid profiling of Mucor rouxii under different stress conditions

scientific article published in June 2006

Diacylglycerol acyltransferase 2 of Mortierella alpina with specificity on long-chain polyunsaturated fatty acids: A potential tool for reconstituting lipids with nutritional value

scientific article published on 16 October 2017

Dissecting metabolic behavior of lipid over-producing strain of Mucor circinelloides through genome-scale metabolic network and multi-level data integration

scientific article published on 23 May 2018

Elongation of C16:0 to C18:0 fatty acids in methylotrophic yeast Hansenula polymorpha CBS 1976 and fatty acid auxotrophic mutants.

scientific article

Enhancing Genome-Scale Model by Integrative Exometabolome and Transcriptome: Unveiling Carbon Assimilation towards Sphingolipid Biosynthetic Capability of Cordyceps militaris

scientific article published in 2022

Ethanol-induced changes in expression profiles of cell growth, fatty acid and desaturase genes of Mucor rouxii

scientific article published on 4 May 2007

Exploring differential traits of lipid-producing stages of the wild type and morphologically engineered strain of Aspergillus oryzae by comparative kinetic modeling

scientific article published on 12 November 2020

Fermentation process development of recombinant Hansenula polymorpha for gamma-linolenic acid production.

scientific article published on November 2010

Functional Characterization of Novel U6 RNA Polymerase III Promoters: Their Implication for CRISPR-Cas9-Mediated Gene Editing in Aspergillus oryzae

scientific article published on 20 September 2019

Genetic modification of essential fatty acids biosynthesis in Hansenula polymorpha

scientific article published in April 2005

Genome Characterization of Oleaginous Aspergillus oryzae BCC7051: A Potential Fungal-Based Platform for Lipid Production

scientific article published in September 2017

Genome mining of fungal lipid-degrading enzymes for industrial applications

scientific article published in August 2015

Genome-scale analysis of the metabolic networks of oleaginous Zygomycete fungi

scientific article published on 27 March 2013

Genome-scale metabolic modeling of Mucor circinelloides and comparative analysis with other oleaginous species

scientific article

Genome-scale metabolic network of Cordyceps militaris useful for comparative analysis of entomopathogenic fungi

scientific article

Heterologous production of polyunsaturated fatty acids in Saccharomyces cerevisiae causes a global transcriptional response resulting in reduced proteasomal activity and increased oxidative stress

scientific article published on 23 December 2010

Identification of flux regulation coefficients from elementary flux modes: A systems biology tool for analysis of metabolic networks

scientific article published in August 2007

Integrative computational approach for genome-based study of microbial lipid-degrading enzymes

scientific article

Lanostane triterpenoids from cultivated fruiting bodies of the basidiomycete Ganoderma australe

scientific article

Metabolic Responses of Carotenoid and Cordycepin Biosynthetic Pathways in Cordyceps militaris under Light-Programming Exposure through Genome-Wide Transcriptional Analysis

scientific article published on 21 August 2020

Metabolic engineering of long chain-polyunsaturated fatty acid biosynthetic pathway in oleaginous fungus for dihomo-gamma linolenic acid production

scientific article published on 10 December 2015

Metabolic traits specific for lipid-overproducing strain of Mucor circinelloides WJ11 identified by genome-scale modeling approach

scientific article published on 07 June 2019

Morphologically engineered strain of Aspergillus oryzae as a cell chassis for production development of functional lipids

scientific article published on 22 August 2019

Novel elongase of Pythium sp. with high specificity on Δ(6)-18C desaturated fatty acids

scientific article published on 09 June 2014

Overexpression of acetyl-CoA carboxylase gene of Mucor rouxii enhanced fatty acid content in Hansenula polymorpha

scientific article published on 5 March 2009

Oxygen-induced expression of Delta(6)-, Delta(9)- and Delta(12)-desaturase genes modulates fatty acid composition in Mucor rouxii

scientific article published in March 2010

Probing Carbon Utilization of Cordyceps militaris by Sugar Transportome and Protein Structural Analysis

scientific article published on 10 February 2020

Promoter analysis of Mucor rouxii delta9-desaturase: its implication for transcriptional regulation in Saccharomyces cerevisiae

scientific article published in September 2005

Reengineering lipid biosynthetic pathways of Aspergillus oryzae for enhanced production of γ-linolenic acid and dihomo-γ-linolenic acid

scientific article published on 27 April 2019

Repertoire of malic enzymes in yeast and fungi: insight into their evolutionary functional and structural significance

scientific article

Sequence- and Structure-Based Functional Annotation and Assessment of Metabolic Transporters in Aspergillus oryzae: A Representative Case Study

scientific article published on 4 May 2016

Significance of fatty acid supplementation on profiles of cell growth, fatty acid, and gene expression of three desaturases in Mucor rouxii

scientific article published on 5 July 2008

Substrate specificity and preference of Delta6-desaturase of Mucor rouxii

scientific article published on 20 April 2005

Systematic development of biomass overproducing Scheffersomyces stipitis for high-cell-density fermentations

scientific article published on 5 February 2016

Systematic genome analysis of a novel arachidonic acid-producing strain uncovered unique metabolic traits in the production of acetyl-CoA-derived products in Mortierellale fungi

scientific article published on 10 March 2020

Systematic optimization of fed-batch simultaneous saccharification and fermentation at high-solid loading based on enzymatic hydrolysis and dynamic metabolic modeling of Saccharomyces cerevisiae.

scientific article published on 27 November 2015

Targeted mutagenesis of a fatty acid Delta6-desaturase from Mucor rouxii: role of amino acid residues adjacent to histidine-rich motif II.

scientific article

The codon-optimized Δ(6)-desaturase gene of Pythium sp. as an empowering tool for engineering n3/n6 polyunsaturated fatty acid biosynthesis

scientific article published on 15 September 2015

The genome-scale metabolic model iIN800 of Saccharomyces cerevisiae and its validation: a scaffold to query lipid metabolism

scientific article

Uncovering global metabolic response to cordycepin production in Cordyceps militaris through transcriptome and genome-scale network-driven analysis.

scientific article

Up-regulated expression of desaturase genes of Mucor rouxii in response to low temperature associates with pre-existing cellular fatty acid constituents ⬇️

scientific article published on November 23, 2010

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